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1,380 Possible Causes for taus

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  • Dementia

    The pathogenesis of AD is complex, involving specific disease-linked proteins (amyloid-beta [Aβ] and tau), inflammation, and neurotransmitter dysregulation.[ncbi.nlm.nih.gov] KEYWORDS: Amyotrophic lateral sclerosis; Positron emission tomography; Tau[ncbi.nlm.nih.gov] The pathogenesis of AD is complex, involving specific disease-linked proteins (amyloid-beta [Aß] and tau), inflammation, and neurotransmitter dysregulation.[doi.org]

  • Otitis Media

    Removing this potential outlier resulted in homogeneity between the remaining studies ( Lambert 1986 ) (Tau² 0.00; Chi² 2.86, df 3 (P 0.41); I² 0%) and an increase in the[doi.org]

  • Pneumonia

    We presented results as the average treatment effect with 95% CI and Tau² and I² estimates.[doi.org]

  • Meningitis

    Proof that it is CSF has rested for many years on the presence of glucose but β-2 (tau) transferrin is a more specific CSF marker.[jnnp.bmj.com]

  • Tauopathy

    These data support investigation of a tau-lowering therapy in human patients who have tau-positive inclusions even after pathological tau deposition has begun.[ncbi.nlm.nih.gov] Administration of anti-tau antibody to tau transgenic mice that had decreased brain soluble tau and interstitial fluid tau resulted in an increase in plasma tau, but this[ncbi.nlm.nih.gov] […] associated with seeded tau pathology in tau transgenic mouse brain.[ncbi.nlm.nih.gov]

  • Progressive Supranuclear Palsy

    APOE ɛ4 carriers had more severe amyloid pathology, but total tau burden and a global cognitive impairment index did not differ from APOE ɛ4 noncarriers.[ncbi.nlm.nih.gov] Comparative biochemistry of tau aggregates shows that they differ in both phosphorylation and content of tau isoforms.[ncbi.nlm.nih.gov] […] diagnosis of neurodegenerative disorders associated with tau protein. 2016 EAN.[ncbi.nlm.nih.gov]

  • Classic Progressive Supranuclear Palsy Syndrome

    Etiology PSP is a 4R tauopathy composed of a preponderance of four-repeat tau isoforms and a characteristic biochemical profile (doublet tau 64 and tau 69).[orpha.net] “It is puzzling why the wasting doesn’t closely relate to the formation of tau pathology.[neura.edu.au] The differences in the rate and areas of accumulation of phosphorylated tau protein correlate with the clinical variants of PSP-tau pathology.[orpha.net]

  • Frontotemporal Dementia

    […] in a 3-repeat G55R tau versus 3-repeat wild-type tau comparison.[ncbi.nlm.nih.gov] Postmortem neuropathological and biochemical data indicate a Pick-like tau pathology but with phosphoserine 262-positive immunoreactivity.[ncbi.nlm.nih.gov] […] protein tau ( MAPT) mutation.[ncbi.nlm.nih.gov]

  • Alzheimer Disease

    The hyperphosphorylation of tau results both from an imbalance between the activities of tau kinases and tau phosphatases and as well as changes in tau's conformation which[ncbi.nlm.nih.gov] This truncated tau can catalyse the conversion of normal soluble tau into aggregated oligomeric and fibrillar tau which, in turn, can spread to neighbouring neurons.[ncbi.nlm.nih.gov] […] of tau was higher than that of Aβ.[ncbi.nlm.nih.gov]

  • Gaucher Disease Type 3

    In the patient's brain, generalized astrogliosis, and enhanced LC3, ubiquitin, and Tau signals were identified in the regions surrounding macrophage clusters, indicating proinflammation[ncbi.nlm.nih.gov]

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