There Are Several Subtypes: Causes & Reasons

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Possible Causes for There Are Several Subtypes

Epidermolysis Bullosa Simplex Type Cockayne-Touraine

The most severe subtype of DEB is Hallopeau-Siemens, it is Autosomal recessive. [kissesforkatie.org]

Mutations in the genes that encode KERATIN-5 and KERATIN-14 have been associated with several subtypes of epidermolysis bullosa simplex. [profiles.uchicago.edu]

The esophagus and anus can be severely involved. Generalized JEB The most severe subtype of generalized JEB is Herlitz or Gravis. [kissesforkatie.org]

Epidermolysis Bullosa Simplex

Several subtypes exist based on the intraepidermal localization of blisters. [orpha.net]

Epidermolysis bullosa simplex type Dowling-Meara (EBS-DM) is one of the most severe subtypes of EBS. [clinicaltrials.gov]

Mutations in the genes that encode keratin-5 and keratin-14 have been associated with several subtypes of epidermolysis bullosa simplex. [icd10data.com]

Epidermolysis Bullosa Simplex Type Kobner

Mutations in the genes that encode KERATIN-5 and KERATIN-14 have been associated with several subtypes of epidermolysis bullosa simplex. [profiles.uchicago.edu]

Epidermolysis Bullosa

Several subtypes exist based on the intraepidermal localization of blisters. [orpha.net]

Unfortunately, Rafi has the most severe subtype of Recessive Dystrophic EB, generalized severe, what they used to call Hallopeau-Siemens. [rafisrun.com]

A severe, generalized subtype causes blistering of the trunk, arms, and neck, and the oral mucosa may be involved. [merckmanuals.com]

Dystrophic Epidermolysis Bullosa

The most severe subtype of DEB is Hallopeau-Siemens, it is Autosomal recessive. [kissesforkatie.org]

Unfortunately, Rafi has the most severe subtype of Recessive Dystrophic EB, generalized severe, what they used to call Hallopeau-Siemens. [rafisrun.com]

We report herein a Chinese patient with the severe generalized subtype of RDEB (RDEB-sev gen) complicated by SCC. [ncbi.nlm.nih.gov]

Junctional Epidermolysis Bullosa

The clinical picture comprises severe subtypes with lethal outcome in the first years of life as well as milder subtypes with localised blistering or minimal symptoms confined [ncbi.nlm.nih.gov]

Another part of this thesis focuses on the less severe subtype JEB, type non-Herlitz (JEB-nH), in which patients do survive to adulthood. [rug.nl]

The Non-Herlitz type includes several subtypes that cause mild to severe blistering of the skin present at birth or shortly thereafter. [2] [3] JEB is inherited in an autosomal [rarediseases.info.nih.gov]

Hereditary Renal Cell Carcinoma

Several JEB subtypes have been described based on clinical features. [orpha.net]

Referral for psychological support should also be considered for children with EB and their family, especially for the more severe subtypes. [dermnetnz.org]

Each type has several subtypes. So far, medical experts have identified over 30 subtypes of EB. [medicalnewstoday.com]

Pretibial Dystrophic Epidermolysis Bullosa

Mutations in the genes that encode KERATIN-5 and KERATIN-14 have been associated with several subtypes of epidermolysis bullosa simplex. [bioportfolio.com]

Referral for psychological support should also be considered for children with EB and their family, especially for the more severe subtypes. [dermnetnz.org]

severe symptoms; presents at birth and involves all skin surfaces with exuberant granulation tissue of skin and possibly upper airway Recessive dystrophic EB: subtypes are [pathologyoutlines.com]

Mucopolysaccharidosis Type 3

However, MPS IIIA is usually the most severe subtype, characterized by earliest onset, rapid clinical progression with severe symptoms, and short survival. [4] The median [en.wikipedia.org]

Type IIIA is the most severe subtype; most patients with type IIIA die during their teenage years. Race The mucopolysaccharidoses are pan-racial. [emedicine.medscape.com]

Mucopolysaccharidosis Type 1

Currently, since no biochemical differences between these subtypes have been identified and their clinical findings overlap, MPS I is now divided into two subtypes: severe [emedicine.medscape.com]

Title Other Names: MPS 1; Attenuated MPS I (subtype, includes Hurler-Scheie and Scheie syndrome); Severe MPS I (subtype, also known as Hurler syndrome); MPS 1; Attenuated [rarediseases.info.nih.gov]

Historically, the most-to-least severe subtypes of MPS I were as follows: Hurler syndrome (MPS IH, OMIM #607014), Hurler-Scheie syndrome (MPS I-HS, OMIM #607015), and Scheie [emedicine.medscape.com]

Epithelioid Mesothelioma

Epithelial Mesothelioma Subtypes Under epithelioid mesothelioma, there are several subtypes that vary based on cellular structure, location and symptoms. [mesotheliomadiagnosis.com]

Staging: Symptoms tend to be more severe in the later stages of diagnosis. [mesotheliomadiagnosis.com]

Typically epithelioid mesothelioma cells are flat or cube-shaped, but when they become cancerous they can take a variety of shapes, depending on subtype. [mesotheliomadiagnosis.com]

Delusional Disorder

Several subtypes of delusional disorder are recognized: Erotomanic: Patients believe that another person is in love with them. [merckmanuals.com]

There are several subtypes of delusional disorder: Erotomanic: People believe that another person is in love with them. [merckmanuals.com]

Holoprosencephaly Type 9

The three main subtypes, in order of decreasing severity are: alobar holoprosencephaly semilobar holoprosencephaly lobar holoprosencephaly Other entities include: syntelencephaly [radiopaedia.org]

Classically three subtypes have been recognized, however additional entities are now included in the spectrum of the disease. [radiopaedia.org]

Connatal Pelizaeus-Merzbacher Disease

Transitional and adult subtypes have a later onset and less severe symptomatology. [hon.ch]

Phenotypic severities of PMD depend on the clinical subtypes of PLP1 abnormalities, deletions/duplications of the entire region and various nucleotide alterations. [nature.com]

Autosomal Recessive Cutis Laxa Type 1C

Autosomal Recessive Cutis Laxa (ARCL) Autosomal Recessive Cutis Laxa (ARCL) ARCL is divided into several subtypes, based both on specific symptoms and the gene which causes [cutislaxa.org]

[…] then further divided into additional subtypes. [cutislaxa.org]

ARCL is divided into ARCL1 (often associated with severe diseases of lung and blood vessels), ARCL2 (characterised by growth or developmental delay), and ARCL3, which are [cutislaxa.org]

Syngnathia - Cleft Palate

The remaining lethal subtypes exhibit more severe and diffuse involvement and are distinguished by the gestational stage of onset and degree of bony fusions [Hall, 19841. [dokumen.tips]

Hallucinogen Persisting Perception Disorder

A large variety of medications may be utilized to alleviate this condition, but with differential results suggesting several subtypes. [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 4A

The symptoms vary from mild to severe. Some subtypes of CMT4 exhibit severe symptoms with early-onset and are classified as Dejerine-Sottas disease. [charcot-marie-toothnews.com]

Genetic Heterogeneity of Charcot-Marie-Tooth Disease Type 4 Several different subtypes of autosomal recessive demyelinating CMT (CMT4) have been identified, each with particular [ncbi.nlm.nih.gov]

Homepage Rare diseases Search Search for a rare disease Charcot-Marie-Tooth disease type 4A Disease definition Charcot-Marie-Tooth disease type 4A (CMT4A) is a subtype of [orpha.net]

Hypomyelinating Leukodystrophy Type 4

Transitional and adult subtypes have a later onset and less severe symptomatology. [hon.ch]

Subtypes Traditionally Pelizaeus-Merzbacher disease has divided into two subtypes: classic connatal: more rare and severe 5 CT CT features, as is the case with many leukodystrophies [radiopaedia.org]

Perisylvian Polymicrogyria with Cerebellar Hypoplasia and Arthrogryposis

BPP is a subtype of a broader condition known as polymicrogyria. The cerebral cortex of the brain normally consists of several deep folds and grooves. [rarediseases.info.nih.gov]

Gaucher Disease Type 3

There are several subtypes based on the presence and severity of neurological involvement. [hon.ch]

Bartter Syndrome

There are several subtypes including ones due to mutations in the renal specific SODIUM-POTASSIUM-CHLORIDE SYMPORTERS. [profiles.umassmed.edu]

There are several subtypes including ones due to mutations in the renal specific sodium-potassium-chloride symporters. [icd10data.com]

It is characterized by severe salt-wasting, HYPOKALEMIA; HYPERCALCIURIA; metabolic ALKALOSIS, and hyper-reninemic HYPERALDOSTERONISM without HYPERTENSION. [profiles.umassmed.edu]

Generalized Dominant Dystrophic Epidermolysis bullosa

severe symptoms; presents at birth and involves all skin surfaces with exuberant granulation tissue of skin and possibly upper airway Recessive dystrophic EB: subtypes are [pathologyoutlines.com]

The Herlitz (also known as Gravis) subtype is the most severe of the subtypes and patients usually do not live past infancy. [aocd.org]

There are several subtypes of more generalized EBS. [ojrd.biomedcentral.com]

Long QT Syndrome 5

subtypes of long QT syndrome. [en.wikipedia.org]

[…] marked QT prolongation, congenital sensorineural deafness, and a greater risk of arrhythmias. [19] The LQT2 subtype is the second-most common form of Romano-Ward syndrome [en.wikipedia.org]

When two copies of the variant are inherited (homozygous, autosomal recessive inheritance) the more severe Jervell and Lange-Nielsen syndrome is found, associated with more [en.wikipedia.org]

Von Willebrand Disease Type 2B

Each subtype is treated differently. Type 3 VWD is the rarest and most severe form. [hemaware.org]

Type 2 has several subtypes. Each of these is described below. It is important for a person with VWD to know which type he or she has. [hog.org]

In this type, which has several subtypes, the von Willebrand factor you do have doesn't function properly. Signs and symptoms tend to be more significant. Type 3. [mayoclinic.org]

Von Willebrand Disease Type 2N

Each subtype is treated differently. Type 3 VWD is the rarest and most severe form. [hemaware.org]

Type 2 has several subtypes. Each of these is described below. It is important for a person with VWD to know which type he or she has. [hog.org]

Within this type are several subtypes: Type 2A: the building blocks that make up the factor (called multimers) are smaller than usual or break down too easily Type 2B: the [kidshealth.org]

Somatic Delusional Disorder

Several subtypes of delusional disorder are recognized and listed below. [healthyplace.com]

There are several subtypes of delusional disorders and some of these include: Persecutory delusion This is the most common form of delusional disorder. [news-medical.net]

There are several different subtypes of delusional disorder. [dualdiagnosis.org]

Polyarticular Juvenile Idiopathic Arthritis

Polyarticular JIA (Poly-JIA) is a severe subtype that can cause joint damage, poor growth and development, limited mobility, and pain. [chop.edu]

Juvenile idiopathic arthritis (JIA) is the umbrella term for several subtypes of arthritis seen in children and adolescents under the age of 16. [childrenshospital.org]

There are several subtypes of JIA 7,8: oligoarticular JIA affected ≤4 joints in the first six months of illness peak age: 1-6 years mainly affects medium and large joints [radiopaedia.org]

Bartholin's Gland Carcinoma

[…] rare to exceedingly rare histological subtypes have been described, such as transitional cell carcinoma, neuroendocrine carcinoma, epithelial myoepithelial carcinoma, Merkel [pathologyoutlines.com]

[…] approximately 10% adenocarcinomas and < 5% adenoid cystic carcinomas (Gynecol Oncol 2001;82:247, Int J Gynecol Cancer 2016;26:785, Int J Gynecol Pathol 2019;38:189) Additionally, several [pathologyoutlines.com]

JC Virus Infection

Type 2 has several variants: subtype 2A is found mainly in the Japanese population and Native Americans (excluding Inuit ); 2B is found in Eurasians; 2D is found in Indians [en.wikipedia.org]