There Are Several Subtypes: Causes & Reasons

Possible Causes for There Are Several Subtypes

Epidermolysis Bullosa Simplex Type Cockayne-Touraine

Mutations in the genes that encode KERATIN-5 and KERATIN-14 have been associated with several subtypes of epidermolysis bullosa simplex [idref.fr]

The most severe subtype of DEB is Hallopeau-Siemens, it is Autosomal recessive. [kissesforkatie.org]

Mutations in the genes that encode KERATIN-5 and KERATIN-14 have been associated with several subtypes of epidermolysis bullosa simplex. [profiles.uchicago.edu]

Epidermolysis Bullosa Simplex

Several subtypes exist based on the intraepidermal localization of blisters. [orpha.net]

Epidermolysis bullosa simplex type Dowling-Meara (EBS-DM) is one of the most severe subtypes of EBS. [clinicaltrials.gov]

Mutations in the genes that encode keratin-5 and keratin-14 have been associated with several subtypes of epidermolysis bullosa simplex. [icd10data.com]

Epidermolysis Bullosa

A severe, generalized subtype causes blistering of the trunk, arms, and neck, and the oral mucosa may be involved. [msdmanuals.com]

People who have a mild subtype develop blisters on the palms of the hands and soles of the feet. In other more severe subtypes, the blisters occur over the entire body. [niams.nih.gov]

Several subtypes exist based on the intraepidermal localization of blisters. [orpha.net]

Epidermolysis Bullosa Simplex Type Kobner

Mutations in the genes that encode KERATIN-5 and KERATIN-14 have been associated with several subtypes of epidermolysis bullosa simplex. [profiles.uchicago.edu]

Dystrophic Epidermolysis Bullosa

The most severe subtype of DEB is Hallopeau-Siemens, it is Autosomal recessive. [kissesforkatie.org]

Unfortunately, Rafi has the most severe subtype of Recessive Dystrophic EB, generalized severe, what they used to call Hallopeau-Siemens. [rafisrun.com]

We report herein a Chinese patient with the severe generalized subtype of RDEB (RDEB-sev gen) complicated by SCC. [ncbi.nlm.nih.gov]

Myosinopathy

Most of Enterobacterales isolates (79%) harbored several types of beta-lactamases genes and 4.1% isolates carried two subtypes of blaCTX-M. [agris.fao.org]

Conclusions.Among the ESBL-producing Enterobacterales isolates blaCTX-M genes were most common (82.6%), the majority of them belonged to the blaCTX-M-1 subtypes (88.8%). [agris.fao.org]

Pagon Stephan Syndrome

Usher Syndrome Type II is less severe. Patients with this subtype have moderate-to-severe congenital hearing loss, RP, and normal vestibular function. [eyewiki.aao.org]

Usher Syndrome Type I is the most severe subtype. It is characterized by profound congenital hearing loss, RP, and absent vestibular function. [eyewiki.aao.org]

It is classified into three subtypes (I, II, and III) according to onset and severity of symptoms. Type II does not have vestibular dysfunction. [eyewiki.aao.org]

Epithelioid Mesothelioma

Epithelial Mesothelioma Subtypes Under epithelioid mesothelioma, there are several subtypes that vary based on cellular structure, location and symptoms. [mesotheliomadiagnosis.com]

Staging: Symptoms tend to be more severe in the later stages of diagnosis. [mesotheliomadiagnosis.com]

Typically epithelioid mesothelioma cells are flat or cube-shaped, but when they become cancerous they can take a variety of shapes, depending on subtype. [mesotheliomadiagnosis.com]

Holoprosencephaly Type 7

For more details, see the article on semilobar holoprosencephaly Lobar holoprosencephaly This is the least severe subtype. [radiopaedia.org]

The three main subtypes, in order of decreasing severity are: alobar holoprosencephaly semilobar holoprosencephaly lobar holoprosencephaly Other entities include: syntelencephaly [radiopaedia.org]

Classically three subtypes have been recognized, however additional entities are now included in the spectrum of the disease. [radiopaedia.org]

Collagenopathy Type 2 - Collagenopathy Type 11

subtypes of Ehlers-Danlos syndrome (EDS), depending on the location of variant (Kuivaniemi et al., 1988; Byers et al., 1997; Raff et al., 2000). [frontiersin.org]

[…] splice-site mutations, multiexon duplication or deletion in COL1A2 has less been reported in classic OI cases but it may be linked to a wide array of clinical OI phenotypes or several [frontiersin.org]

Sclerosing Liposarcoma

[…] recognizable morphologic subtypes Essential features Low grade lipogenic tumor with multiple morphologic subtypes and significant histologic variability Molecularly characterized [pathologyoutlines.com]

[…] by ring or giant marker / rod chromosomes composed of material from 12q13-15 Results in localized amplification of several neighboring genes, including MDM2 Behavior is dependent [pathologyoutlines.com]

[…] composed of mature adipocytes and stromal cells with at least focal cytologic atypia Adipocytic component and background cellular constituents vary in concentration and lead to several [pathologyoutlines.com]

Holoprosencephaly Type 4

For more details, see the article on semilobar holoprosencephaly Lobar holoprosencephaly This is the least severe subtype. [radiopaedia.org]

Classically three subtypes have been recognized, however additional entities are now included in the spectrum of the disease. [radiopaedia.org]

Holoprosencephaly Type 8

For more details, see the article on semilobar holoprosencephaly Lobar holoprosencephaly This is the least severe subtype. [radiopaedia.org]

Classically three subtypes have been recognized, however additional entities are now included in the spectrum of the disease. [radiopaedia.org]

Brachydactyly Type C

There are 5 types (A–E) and several subtypes (A1–A4; E1–E3). It has an autosomal dominant pattern of inheritance with variable penetrance. [analesdepediatria.org]

Holoprosencephaly Type 9

Classically three subtypes have been recognized, however additional entities are now included in the spectrum of the disease. [radiopaedia.org]

Joubert Syndrome Type 5

There are several subtypes of Joubert syndrome depending on clinical signs and symptoms. [rarediseases.org]

Rod-cone dystrophy MedGen UID: 1632921 •Concept ID: C4551714 • Disease or Syndrome An inherited retinal disease subtype in which the rod photoreceptors appear to be more severely [ncbi.nlm.nih.gov]

Several mutant genes of JSRD could also exist in other syndromes, such as Meckel syndrome (mutations of RPGRIP1L and CEP290 genes[21]), and share some features with JSRD.[ [journals.lww.com]

Delusional Disorder

Several subtypes of delusional disorder are recognized: Erotomanic: Patients believe that another person is in love with them. [msdmanuals.com]

There are several subtypes of delusional disorder: Erotomanic: People believe that another person is in love with them. [msdmanuals.com]

Mastocytic Enterocolitis

subtypes: Indolent / smoldering SM Advanced Aggressive SM SM with associated hematological neoplasms Mast cell leukemia Irritable bowel syndrome (IBS): Mast cells can be [pathologyoutlines.com]

[…] criterion to diagnose SM is the presence of multifocal clusters of spindled mast cells in the bone marrow, absent in mastocytic colitis (Am J Hematol 2021;96:508) WHO recognizes several [pathologyoutlines.com]

Syngnathia - Cleft Palate

The remaining lethal subtypes exhibit more severe and diffuse involvement and are distinguished by the gestational stage of onset and degree of bony fusions [Hall, 19841. [dokumen.tips]

Apocrine Adenocarcinoma

Yet, among these ER(-) tumors, several teams have identified the molecular apocrine breast cancer (MA) subtype, characterized by AR expression and AR pathway activation on [breast-cancer-research.biomedcentral.com]

Indeed, although sometimes reported to belong to several molecular subtypes of breast cancer [25], morphological apocrine carcinomas are almost always ER(-) tumors [26] and [breast-cancer-research.biomedcentral.com]

Linear Hamartoma Syndrome

subtypes of generalized basaloid follicular hamartoma have been noted: (1) sporadic: multiple lesions without systemic disease; (2) inherited: autosomal dominant disease [ijdvl.com]

[…] is characterized by alopecic patches or unilateral linear lesions which follow the lines of Blaschko.[2],[4] The generalized form is less common tends to be inherited.[2] Several [ijdvl.com]

Onychocytic Matricoma

Several subtypes of OCM have been proposed according to both histological features (acanthotic type, acanthotic and papillomatous type, keratogenous type with retarded maturation [dermsinica.org]

Junctional Epidermolysis Bullosa

The clinical picture comprises severe subtypes with lethal outcome in the first years of life as well as milder subtypes with localised blistering or minimal symptoms confined [ncbi.nlm.nih.gov]

Another part of this thesis focuses on the less severe subtype JEB, type non-Herlitz (JEB-nH), in which patients do survive to adulthood. [rug.nl]

The Non-Herlitz type includes several subtypes that cause mild to severe blistering of the skin present at birth or shortly thereafter. [2] [3] JEB is inherited in an autosomal [rarediseases.info.nih.gov]

Perisylvian Polymicrogyria with Cerebellar Hypoplasia and Arthrogryposis

BPP is a subtype of a broader condition known as polymicrogyria. The cerebral cortex of the brain normally consists of several deep folds and grooves. [rarediseases.info.nih.gov]

Congenital Coxa Valga

subtypes: Congenital coxa vara, which is present at birth and is caused by an embryonic limb bud abnormality. [physio-pedia.com]

[…] as the angle between the neck and shaft of the femur being less than 110 – 120 ° (which is normally between 135 ° - 145 °) in children. [2] Coxa vara is classified into several [physio-pedia.com]

Perioral Dermatitis

Click here for more images Lupoid perioral dermatitis This is a severe subtype of POD. Eruptions are denser and larger with red-brown papules. [dermnetnz.org]

subtype of the disease. [ncbi.nlm.nih.gov]

The immediate peri-vermillion skin is often spared, only rarely is it affected in severe cases. [dermnetnz.org]

Hyper-IgM Syndrome Type 5

Several subtypes of hyper-IgM immunodeficiency syndrome exist depending upon the location of genetic mutation. [profiles.viictr.org]

Cribriform Comedo-Type Adenocarcinoma

It is a heterogeneous disease with several histologic subtypes, and some of them are associated with adverse prognostic factors. [pubmed.ncbi.nlm.nih.gov]

[…] of the tumor Severity of the signs and symptoms Age of the individual Overall health status of the individual The treatment preferences of the individual The staging system [dovemed.com]

The treatment of colorectal cancer may depend upon a consideration of the following set of factors: The histological subtype of the cancer Stage of the cancer Size and location [dovemed.com]

Hereditary Renal Cell Carcinoma

Several JEB subtypes have been described based on clinical features. [orpha.net]

Referral for psychological support should also be considered for children with EB and their family, especially for the more severe subtypes. [dermnetnz.org]

Each type has several subtypes. So far, medical experts have identified over 30 subtypes of EB. [medicalnewstoday.com]

Hallucinogen Persisting Perception Disorder

A large variety of medications may be utilized to alleviate this condition, but with differential results suggesting several subtypes. [ncbi.nlm.nih.gov]