Thick Lips: Causes & Reasons

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Possible Causes for Thick Lips

Mucopolysaccharidosis Type 2

Signs and symptoms of MPS 2A include: Macrocephaly Coarse facies Large rounded cheeks Thick lips Hypertrophic adenoids and tonsils Macroglossia Hoarse voice Short neck Retinal [symptoma.com]

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Umbilical hernia 0001537 5%-29% of people have these symptoms Abnormal [rarediseases.info.nih.gov]

[…] paying attention [ more ] 0000736 Sleep apnea Pauses in breathing while sleeping 0010535 Sleep-wake cycle disturbance 0006979 Splenomegaly Increased spleen size 0001744 Thick [rarediseases.info.nih.gov]

Atkin Syndrome

[…] supraorbital ridges Thick lower lip vermilion Mental retardation Coarse face Prominent/Broad forehead Supraorbital ridges Wide-set eyes Broad nose tip Anteverted nostrils [checkorphan.org]

[…] vermilion border 58 31 hallmark (90%) Very frequent (99-80%) HP:0012471 7 short stature 58 31 hallmark (90%) Very frequent (99-80%) HP:0004322 8 everted lower lip vermilion [malacards.org]

lips. [whonamedit.com]

Donohue Syndrome

The patient showed typical "elfin-like" face with wide nostrils and thick lips, large and low-set ears, and dysplastic nails. [ncbi.nlm.nih.gov]

lips), reduced subcutaneous fat, distended abdomen, and enlarged external genitalia and nipples. [ncbi.nlm.nih.gov]

The patient is a Japanese boy with acanthosis nigricans, lack of subcutaneous fat, hirsutism, thick lips, gum hypertrophy and extremely high insulin levels (6702 mU/mL). [ncbi.nlm.nih.gov]

Costello Syndrome

Ultrasonographic morphological fetal face analysis found abnormal thickness of the skin in the prefrontal area, thick dysplastic ears, thick lips and deep-set creases in the [ncbi.nlm.nih.gov]

Major Features Dysphagia / Feeding difficulty / Gastrostomy tube (g-tube) (95%) Postnatal short stature (97%) Characteristic facial features (98%) Thick lips (95%) Loose skin [web.archive.org]

lips, thick lobes, ears set low and large head), mental retardation, dry and thick leg, arm, feet and hand skin, and excessively flexible finger joints. [ic.steadyhealth.com]

Mucopolysaccharidosis Type 1

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

These symptoms may include kyphosis (curvature of the spine causing a “lump on the back”), joint stiffness, coarse facial features (flattened nose bridge, thick lips and an [luriechildrens.org]

Some of the signs and symptoms of MPS I are: Coarsening of facial features (usually the first abnormality detected at 3-6 months of age) Enlarged mouth with thick lips Enlarged [medicinenet.com]

Hypertrichotic Osteochondrodysplasia

[…] eyebrow Bushy eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Thick vermilion border Full lips Increased volume of lip Plump lips [rarediseases.info.nih.gov]

lips; Gingival hypertrophy; [Neck]; Short neck CARDIOVASCULAR: [Heart]; Cardiomegaly; Pericardial effusions; Congenital hypertrophy of left ventricle; Bicuspid aortic valve [genome.jp]

The facial gestalt included: macrocephaly, thick and bushy eyebrows, epicanthal folds, a broad nasal bridge, a bulbus nose, a long philtrum, thick lips (particularly the lower [karger.com]

Acromegaly

The facial aspect is characteristic and includes a widened and thickened nose, prominent cheekbones, forehead bulges, thick lips and marked facial lines. [orpha.net]

A person with acromegaly usually has large hands and feet, thick lips, coarse facial features, a jutting forehead and jaw, and widely spaced teeth. [hormone.org]

Aspartylglucosaminuria

lips and a square shape of face, was found to be present long before the coarsening begins. [ncbi.nlm.nih.gov]

[…] consistent dysmorphic gestalt with hypertelorism, a short and broad nose with round nares, simple often small ears with small or missing lobule and modest folding of helices, thick [ncbi.nlm.nih.gov]

Mucopolysaccharidosis

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

Some of the signs and symptoms of MPS I are: Coarsening of facial features (usually the first abnormality detected at 3-6 months of age) Enlarged mouth with thick lips Enlarged [medicinenet.com]

Kanzaki Disease

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Tinnitus Ringing in ears Ringing in the ears [ more ] 0000360 Percent [rarediseases.info.nih.gov]

Individuals with Schindler disease type II may also develop distinctive facial features including mildly coarse features, thick lips, a depressed nasal bridge and an enlarged [rarediseases.org]

Another patient had lymphedema, cardiomegaly, corneal opacity and slight facial coarsening including thick lips, a depressed nasal bridge and an enlarged tip of the nose. [rarediseases.info.nih.gov]

Clark-Baraitser Syndrome

Facial manifestations include prominent supraorbital ridges, large ears, broad nasal tip, thick lower lip, and small upper lateral incisors. (Courtesy of Dr. [oxfordmedicine.com]

[…] lower lip, and microdontia of upper lateral incisors, and the mother was moderately obese. [findzebra.com]

[…] lower lip. [ghr.nlm.nih.gov]

Autosomal Recessive Hypohidrotic Ectodermal Dysplasia Type 10B

21 102100 Acromegaloid changes, cutis vertcis gyrata, and corneal leukoma (Rosenthal-Kloepfer syndrome) 22 102150 Acromegaloid facial appearance syndrome (AFA syndrome) (Thick [becomerich.lab.u-ryukyu.ac.jp]

Some people with hypohidrotic ectodermal dysplasia have distinctive facial features, including a prominent forehead, thick lips, and a flattened bridge of the nose. [ghr.nlm.nih.gov]

Palmoplantar hyperkeratosis Plantar hyperkeratosis Dysphagia Abnormality of the skeletal system Narrow forehead Hyperpigmentation of the skin Poor suck Thickened helices Thick [mendelian.co]

Kahrizi Syndrome

lips. [omim.org]

Related phenotypes are thick lower lip vermilion and bulbous nose Disease Ontology : 12 An autosomal recessive disease that is characterized by mental retardation, cataracts [malacards.org]

[…] syndrome characterized by severe mental retardation, cataracts with onset in late adolescence, kyphosis, contractures of large joints, bulbous nose with broad nasal bridge, and thick [omim.org]

3M Syndrome

lips, raised eyebrows, severe maxillary hypoplasia, melancholic facies, delayed severe dental eruption, lack of facial mass growth. [scielo.org.co]

At birth he presented with a broad, fleshy nose with anteverted nostrils, thick and patulous lips, a square chin, curvilinear shaped eyebrows without synophrys, short thorax [ijponline.biomedcentral.com]

[…] characteristic are; delayed prenatal growth, severe postnatal growth, facial dysmorphia, radiological abnormalities, presence of dolichocephaly, frontal bulging, triangular face, thick [scielo.org.co]

Mucopolysaccharidosis Type 1 H/S

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

They also tend to look similar: Shorter than average, with stocky build Large head, bulging forehead Thick lips, widely spaced teeth, and large tongue Short, flat nose with [webmd.com]

Some of the signs and symptoms of MPS I are: Coarsening of facial features (usually the first abnormality detected at 3-6 months of age) Enlarged mouth with thick lips Enlarged [medicinenet.com]

Incontinentia Pigmenti Achromians

Other of her symptoms--thick lips and myopia--have been reported earlier. [ncbi.nlm.nih.gov]

[…] lower lip vermilion Increased volume of lower lip Plump lower lip Prominent lower lip [ more ] 0000179 Showing of 58 | Last updated: 7/1/2019 Neurological problems are found [rarediseases.info.nih.gov]

0002808 Macular hypopigmented whorls, streaks, and patches 0005593 Radial deviation of finger 0009466 Somatic mosaicism 0001442 Syndactyly Webbed fingers or toes 0001159 Thick [rarediseases.info.nih.gov]

Dermatosparaxis

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Umbilical hernia 0001537 Wide anterior fontanel Wider-than-typical [rarediseases.info.nih.gov]

Characteristic facial appearance, sometimes called the "Madonna face", including lobeless ears, thick nose and lips, and prominent eyes. Spontaneous pneumothorax. [patient.info]

Decreased body height Small stature [ more ] 0004322 Short toe Short toes Stubby toes [ more ] 0001831 Soft, doughy skin 0001027 Spontaneous neonatal pneumothorax 0004876 Thick [rarediseases.info.nih.gov]

Williams-Beuren Syndrome

lips, small jaw, dental anomalies, hoarse voice, strabismus, stellate iris pattern, supravalvular aortic stenosis (SVAS), pulmonary artery stenosis, mitral valve prolapse [scielo.br]

Such characteristic facial features may include a round face, full cheeks, thick lips, a large mouth that is usually held open, and a broad nasal bridge with nostrils that [rarediseases.org]

lips, and long nasolabial philtrum [1, 2, 5]. [hindawi.com]

Fucosidosis

[…] eyebrow Bushy eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Thick lower lip vermilion Increased volume of lower lip Plump lower [rarediseases.info.nih.gov]

Abnormal curving of the spine 0002650 Shield chest 0000914 Short stature Decreased body height Small stature [ more ] 0004322 Splenomegaly Increased spleen size 0001744 Thick [rarediseases.info.nih.gov]

Marshall Syndrome

[…] lower lip vermilion Increased volume of lower lip Plump lower lip Prominent lower lip [ more ] 0000179 Thick upper lip vermilion Full upper lip Increased volume of upper [rarediseases.info.nih.gov]

lip Plump upper lip Prominent upper lip Thick upper lip [ more ] 0000215 Wide nasal bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of [rarediseases.info.nih.gov]

Sensorineural hearing impairment 0000407 Short nose Decreased length of nose Shortened nose [ more ] 0003196 Short stature Decreased body height Small stature [ more ] 0004322 Thick [rarediseases.info.nih.gov]

Nakajo Syndrome

The eye lids can appear rather thick or swollen with a reddish purple colour and the lips can look swollen. [printo.it]

Coffin-Lowry Syndrome

lips, a thick nasal septum with anteverted nares, and irregular or missing teeth. [ncbi.nlm.nih.gov]

[…] everted lips, and a thick nasal septum with anteverted nares. [orpha.net]

Cof·fin-Low·ry syn·drome ( kof'ĭn low'rē ), [MIM*303600] characterized by coarse facial features with bulbous nose, large ears, and thick lips; short stature; tapered fingers [medical-dictionary.thefreedictionary.com]

Immunodeficiency Type 23

Drs. Robert Kotloff and Francis McCormack have assembled an expert team of authors on the topic of Rare and Orphan Lung Diseases. Articles include: Lymphangioleiomyomatosis, Pulmonary Lymphangiomatosis, Langerhans Cell Histiocytosis and other Histiocytic Diseases of the Lung, Pulmonary Alveolar Proteinosis,[…] [books.google.com]

Patterson Pseudoleprechaunism Syndrome

lips ... [ibis-birthdefects.org]

lips; an abnormally large mouth (macrostomia); and widely spaced eyes (hyptertelorism). [rarediseases.org]

Apostematous Glandular Cheilitis

which secrete thick saliva. [longdom.org]

[…] of a clear, thick mucus; and variable inflammation. [2] Enlargement and chronic exposure of the mucous membrane on the lower lip becomes affected by the environment, leading [rarediseases.info.nih.gov]

Thick mucoid material can be obtained by manual compression of the lip and the same can be dried on the lip surface. Rarely, this mucoid material can be purulent. [longdom.org]

Lenz-Majewski Syndrome

lips, micrognathia), failure to thrive, mental retardation, sparse hair, enamel hypoplasia, loose skin, and skeletal abnormalities. [accessanesthesiology.mhmedical.com]

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Wide mouth Broad mouth Large mouth [ more ] 0000154 5%-29% of people [rarediseases.info.nih.gov]

Lenz-Majewski-Like Syndrome: Mesoectodermal dysplasia with macrocephaly, specific facial features (exophthalmos, broad nasal root, anteverted nostrils, large auricles, thick [accessanesthesiology.mhmedical.com]

Spondyloepimetaphyseal Dysplasia Type SPONASTRIME

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 5%-29% of people have these symptoms Cataract Clouding of the lens [rarediseases.info.nih.gov]

[…] range of motion 0005692 Kyphosis Hunched back Round back [ more ] 0002808 Muscular hypotonia Low or weak muscle tone 0001252 Scoliosis Abnormal curving of the spine 0002650 Thick [rarediseases.info.nih.gov]

3M Syndrome Type 1

All have long triangular faces with pointed chins, but other features may be present such as thick lips, large ears, fleshy upturned nose, or prominent mouth. [wiki.ggc.edu]

Prominent premaxilla, hypoplastic maxilla, thick patulous lips, high-arched palate, median fissured tongue, delayed eruption of teeth with enamel hypocalcification and malocclusion [ncbi.nlm.nih.gov]

BOD Syndrome

Coarse facial features are mainly consistent with wide nose with anteverted nostrils and flat nasal bridge, wide mouth with thick lips, thick eyebrows, synophrys. [bredagenetics.com]

This includes a flat nasal bridge, broad nose, wide mouth, thick lips, and in some cases, thick eyebrows, long eyelashes, palate malformations, a large tongue (macroglossia [encyclopedia.com]

Bilateral Sensorineural Hearing Loss

Extraoral examination of the father and son showed the presence of thick eyebrows, eyelashes, bulbous nose, floppy ears, and thick lips with prominent maxilla and mandible [jdrntruhs.org]

and thick lips. ( b ) Gingival overgrowth with displacement of maxillary canine. [nature.com]

lips, macroglossia and widely spaced teeth Anderson-Fabry disease[ 29, 30 ] Painful crises on extremities and abdomen, angiokeratomas of skin, labial mucosa and buccal mucosa [wjgnet.com]