Thick Lips: Causes & Reasons

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Possible Causes for Thick Lips

Atkin Syndrome

[…] supraorbital ridges Thick lower lip vermilion Mental retardation Coarse face Prominent/Broad forehead Supraorbital ridges Wide-set eyes Broad nose tip Anteverted nostrils [checkorphan.org]

[…] vermilion border 58 31 hallmark (90%) Very frequent (99-80%) HP:0012471 7 short stature 58 31 hallmark (90%) Very frequent (99-80%) HP:0004322 8 everted lower lip vermilion [malacards.org]

lips. [whonamedit.com]

Donohue Syndrome

The patient showed typical "elfin-like" face with wide nostrils and thick lips, large and low-set ears, and dysplastic nails. [ncbi.nlm.nih.gov]

lips), reduced subcutaneous fat, distended abdomen, and enlarged external genitalia and nipples. [ncbi.nlm.nih.gov]

The patient is a Japanese boy with acanthosis nigricans, lack of subcutaneous fat, hirsutism, thick lips, gum hypertrophy and extremely high insulin levels (6702 mU/mL). [ncbi.nlm.nih.gov]

Mucopolysaccharidosis Type 2

Signs and symptoms of MPS 2A include: Macrocephaly Coarse facies Large rounded cheeks Thick lips Hypertrophic adenoids and tonsils Macroglossia Hoarse voice Short neck Retinal [symptoma.com]

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Umbilical hernia 0001537 5%-29% of people have these symptoms Abnormal [rarediseases.info.nih.gov]

[…] paying attention [ more ] 0000736 Sleep apnea Pauses in breathing while sleeping 0010535 Sleep-wake cycle disturbance 0006979 Splenomegaly Increased spleen size 0001744 Thick [rarediseases.info.nih.gov]

Costello Syndrome

Ultrasonographic morphological fetal face analysis found abnormal thickness of the skin in the prefrontal area, thick dysplastic ears, thick lips and deep-set creases in the [ncbi.nlm.nih.gov]

Major Features Dysphagia / Feeding difficulty / Gastrostomy tube (g-tube) (95%) Postnatal short stature (97%) Characteristic facial features (98%) Thick lips (95%) Loose skin [web.archive.org]

lips, thick lobes, ears set low and large head), mental retardation, dry and thick leg, arm, feet and hand skin, and excessively flexible finger joints. [ic.steadyhealth.com]

Mucopolysaccharidosis Type 1

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Thickened skin Thick skin 0001072 Tracheal stenosis Narrowing of [rarediseases.info.nih.gov]

Some of the signs and symptoms of MPS I are: Coarsening of facial features (usually the first abnormality detected at 3-6 months of age) Enlarged mouth with thick lips Enlarged [medicinenet.com]

Hypertrichotic Osteochondrodysplasia

[…] eyebrow Bushy eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Thick vermilion border Full lips Increased volume of lip Plump lips [rarediseases.info.nih.gov]

lips; Gingival hypertrophy; [Neck]; Short neck CARDIOVASCULAR: [Heart]; Cardiomegaly; Pericardial effusions; Congenital hypertrophy of left ventricle; Bicuspid aortic valve [genome.jp]

[…] nares, long and large philtrum, prominent mouth with full lips and macroglossia. [orpha.net]

Acromegaly

The facial aspect is characteristic and includes a widened and thickened nose, prominent cheekbones, forehead bulges, thick lips and marked facial lines. [orpha.net]

A person with acromegaly usually has large hands and feet, thick lips, coarse facial features, a jutting forehead and jaw, and widely spaced teeth. [hormone.org]

Aspartylglucosaminuria

lips and a square shape of face, was found to be present long before the coarsening begins. [ncbi.nlm.nih.gov]

[…] consistent dysmorphic gestalt with hypertelorism, a short and broad nose with round nares, simple often small ears with small or missing lobule and modest folding of helices, thick [ncbi.nlm.nih.gov]

Mucopolysaccharidosis

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

These symptoms may include kyphosis (curvature of the spine causing a “lump on the back”), joint stiffness, coarse facial features (flattened nose bridge, thick lips and an [luriechildrens.org]

Some of the signs and symptoms of MPS I are: Coarsening of facial features (usually the first abnormality detected at 3-6 months of age) Enlarged mouth with thick lips Enlarged [medicinenet.com]

Kanzaki Disease

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Tinnitus Ringing in ears Ringing in the ears [ more ] 0000360 Percent [rarediseases.info.nih.gov]

Individuals with Schindler disease type II may also develop distinctive facial features including mildly coarse features, thick lips, a depressed nasal bridge and an enlarged [rarediseases.org]

Another patient had lymphedema, cardiomegaly, corneal opacity and slight facial coarsening including thick lips, a depressed nasal bridge and an enlarged tip of the nose. [rarediseases.info.nih.gov]

Clark-Baraitser Syndrome

Facial manifestations include prominent supraorbital ridges, large ears, broad nasal tip, thick lower lip, and small upper lateral incisors. (Courtesy of Dr. [oxfordmedicine.com]

[…] lower lip, and microdontia of upper lateral incisors, and the mother was moderately obese. [findzebra.com]

[…] lower lip. [ghr.nlm.nih.gov]

Mucopolysaccharidosis Type 1 H/S

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

They also tend to look similar: Shorter than average, with stocky build Large head, bulging forehead Thick lips, widely spaced teeth, and large tongue Short, flat nose with [webmd.com]

Some of the signs and symptoms of MPS I are: Coarsening of facial features (usually the first abnormality detected at 3-6 months of age) Enlarged mouth with thick lips Enlarged [medicinenet.com]

Incontinentia Pigmenti Achromians

Other of her symptoms--thick lips and myopia--have been reported earlier. [ncbi.nlm.nih.gov]

[…] lower lip vermilion Increased volume of lower lip Plump lower lip Prominent lower lip [ more ] 0000179 Showing of 58 | Last updated: 7/1/2019 Neurological problems are found [rarediseases.info.nih.gov]

0002808 Macular hypopigmented whorls, streaks, and patches 0005593 Radial deviation of finger 0009466 Somatic mosaicism 0001442 Syndactyly Webbed fingers or toes 0001159 Thick [rarediseases.info.nih.gov]

Autosomal Recessive Hypohidrotic Ectodermal Dysplasia Type 10B

21 102100 Acromegaloid changes, cutis vertcis gyrata, and corneal leukoma (Rosenthal-Kloepfer syndrome) 22 102150 Acromegaloid facial appearance syndrome (AFA syndrome) (Thick [becomerich.lab.u-ryukyu.ac.jp]

Some people with hypohidrotic ectodermal dysplasia have distinctive facial features, including a prominent forehead, thick lips, and a flattened bridge of the nose. [ghr.nlm.nih.gov]

Palmoplantar hyperkeratosis Plantar hyperkeratosis Dysphagia Abnormality of the skeletal system Narrow forehead Hyperpigmentation of the skin Poor suck Thickened helices Thick [mendelian.co]

Kahrizi Syndrome

Diseases related with Cataract and Thick lower lip vermilion In the following list you will find some of the most common rare diseases related to Cataract and Thick lower [mendelian.co]

lips. [omim.org]

lip vermilion that can help you solving undiagnosed cases. [mendelian.co]

3M Syndrome

lips, raised eyebrows, severe maxillary hypoplasia, melancholic facies, delayed severe dental eruption, lack of facial mass growth. [scielo.org.co]

At birth he presented with a broad, fleshy nose with anteverted nostrils, thick and patulous lips, a square chin, curvilinear shaped eyebrows without synophrys, short thorax [ijponline.biomedcentral.com]

[…] characteristic are; delayed prenatal growth, severe postnatal growth, facial dysmorphia, radiological abnormalities, presence of dolichocephaly, frontal bulging, triangular face, thick [scielo.org.co]

Dermatosparaxis

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Umbilical hernia 0001537 Wide anterior fontanel Wider-than-typical [rarediseases.info.nih.gov]

Characteristic facial appearance, sometimes called the "Madonna face", including lobeless ears, thick nose and lips, and prominent eyes. Spontaneous pneumothorax. [patient.info]

Decreased body height Small stature [ more ] 0004322 Short toe Short toes Stubby toes [ more ] 0001831 Soft, doughy skin 0001027 Spontaneous neonatal pneumothorax 0004876 Thick [rarediseases.info.nih.gov]

Williams-Beuren Syndrome

lips, small jaw, dental anomalies, hoarse voice, strabismus, stellate iris pattern, supravalvular aortic stenosis (SVAS), pulmonary artery stenosis, mitral valve prolapse [scielo.br]

Such characteristic facial features may include a round face, full cheeks, thick lips, a large mouth that is usually held open, and a broad nasal bridge with nostrils that [rarediseases.org]

lips, and long nasolabial philtrum [1, 2, 5]. [hindawi.com]

Fucosidosis

[…] eyebrow Bushy eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Thick lower lip vermilion Increased volume of lower lip Plump lower [rarediseases.info.nih.gov]

Abnormal curving of the spine 0002650 Shield chest 0000914 Short stature Decreased body height Small stature [ more ] 0004322 Splenomegaly Increased spleen size 0001744 Thick [rarediseases.info.nih.gov]

Marshall Syndrome

[…] lower lip vermilion Increased volume of lower lip Plump lower lip Prominent lower lip [ more ] 0000179 Thick upper lip vermilion Full upper lip Increased volume of upper [rarediseases.info.nih.gov]

lip Plump upper lip Prominent upper lip Thick upper lip [ more ] 0000215 Wide nasal bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of [rarediseases.info.nih.gov]

Sensorineural hearing impairment 0000407 Short nose Decreased length of nose Shortened nose [ more ] 0003196 Short stature Decreased body height Small stature [ more ] 0004322 Thick [rarediseases.info.nih.gov]

Nakajo Syndrome

The eye lids can appear rather thick or swollen with a reddish purple colour and the lips can look swollen. [printo.it]

Coffin-Lowry Syndrome

lips, a thick nasal septum with anteverted nares, and irregular or missing teeth. [ncbi.nlm.nih.gov]

[…] everted lips, and a thick nasal septum with anteverted nares. [orpha.net]

Cof·fin-Low·ry syn·drome ( kof'ĭn low'rē ), [MIM*303600] characterized by coarse facial features with bulbous nose, large ears, and thick lips; short stature; tapered fingers [medical-dictionary.thefreedictionary.com]

Immunodeficiency Type 23

Drs. Robert Kotloff and Francis McCormack have assembled an expert team of authors on the topic of Rare and Orphan Lung Diseases. Articles include: Lymphangioleiomyomatosis, Pulmonary Lymphangiomatosis, Langerhans Cell Histiocytosis and other Histiocytic Diseases of the Lung, Pulmonary Alveolar Proteinosis,[…] [books.google.com]

Patterson Pseudoleprechaunism Syndrome

lips ... [ibis-birthdefects.org]

lips; an abnormally large mouth (macrostomia); and widely spaced eyes (hyptertelorism). [rarediseases.org]

Apostematous Glandular Cheilitis

which secrete thick saliva. [longdom.org]

[…] of a clear, thick mucus; and variable inflammation. [2] Enlargement and chronic exposure of the mucous membrane on the lower lip becomes affected by the environment, leading [rarediseases.info.nih.gov]

Thick mucoid material can be obtained by manual compression of the lip and the same can be dried on the lip surface. Rarely, this mucoid material can be purulent. [longdom.org]

Spondyloepimetaphyseal Dysplasia Type SPONASTRIME

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 5%-29% of people have these symptoms Cataract Clouding of the lens [rarediseases.info.nih.gov]

[…] range of motion 0005692 Kyphosis Hunched back Round back [ more ] 0002808 Muscular hypotonia Low or weak muscle tone 0001252 Scoliosis Abnormal curving of the spine 0002650 Thick [rarediseases.info.nih.gov]

Lenz-Majewski Syndrome

lips, micrognathia), failure to thrive, mental retardation, sparse hair, enamel hypoplasia, loose skin, and skeletal abnormalities. [accessanesthesiology.mhmedical.com]

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Wide mouth Broad mouth Large mouth [ more ] 0000154 5%-29% of people [rarediseases.info.nih.gov]

Lenz-Majewski-Like Syndrome: Mesoectodermal dysplasia with macrocephaly, specific facial features (exophthalmos, broad nasal root, anteverted nostrils, large auricles, thick [accessanesthesiology.mhmedical.com]

3M Syndrome Type 1

All have long triangular faces with pointed chins, but other features may be present such as thick lips, large ears, fleshy upturned nose, or prominent mouth. [wiki.ggc.edu]

Prominent premaxilla, hypoplastic maxilla, thick patulous lips, high-arched palate, median fissured tongue, delayed eruption of teeth with enamel hypocalcification and malocclusion [ncbi.nlm.nih.gov]

BOD Syndrome

Coarse facial features are mainly consistent with wide nose with anteverted nostrils and flat nasal bridge, wide mouth with thick lips, thick eyebrows, synophrys. [bredagenetics.com]

This includes a flat nasal bridge, broad nose, wide mouth, thick lips, and in some cases, thick eyebrows, long eyelashes, palate malformations, a large tongue (macroglossia [encyclopedia.com]

Colpocephaly

[…] alae (HP:0009928); short philtrum (HP:0000322), wide philtrum (HP:0000289); wide mouth (HP:0000154); thick lower lip vermillion (HP:0000179), thick upper lip vermillion [databases.lovd.nl]

[…] alae (HP:0009928); normal philtrum (-HP:0000288); wide mouth (HP:0000154); thick lower lip vermillion (HP:0000179), thick upper lip vermillion (HP:0000215); no cleft palate [databases.lovd.nl]

[…] lower lip vermillion (HP:0000179), thick upper lip vermillion (HP:0000215); no cleft palate (-HP:0000175); normal ears (-HP:0000598), no ear tags (-HP:0000384); hypertrichosis [databases.lovd.nl]