Thick Lips: Causes & Reasons

Possible Causes for Thick Lips

[…] supraorbital ridges Thick lower lip vermilion Mental retardation Coarse face Prominent/Broad forehead Supraorbital ridges Wide-set eyes Broad nose tip Anteverted nostrils [checkorphan.org]

lips. [whonamedit.com]

[…] vermilion border 58 31 hallmark (90%) Very frequent (99-80%) HP:0012471 7 short stature 58 31 hallmark (90%) Very frequent (99-80%) HP:0004322 8 everted lower lip vermilion [malacards.org]

Donohue Syndrome

[…] extreme insulin resistance that is characterized especially by intrauterine and postnatal growth retardation, skin abnormalities, hirsutism, emaciation, widely spaced eyes, thick [merriam-webster.com]

lips, low-set ears, enlarged breasts and clitoromegaly. [indianpediatrics.net]

Almost no cases survive beyond early infancy (under 3 years). elfin facial features enlarged ears which are set low a flattened nose thick lips orbital hypertelorism endocrine [radiopaedia.org]

Costello Syndrome

The characteristic facial profile includes low set ears, thick lips, macrocephaly, depressed nasal bridge and widening of nostrils. [radiopaedia.org]

Ultrasonographic morphological fetal face analysis found abnormal thickness of the skin in the prefrontal area, thick dysplastic ears, thick lips and deep-set creases in the [ncbi.nlm.nih.gov]

His face had coarse features with low-set ears, mild ptosis and a minimally depressed nasal bridge with wide nostrils, thick lips and low frontal hairline [Figure - 2]. [ijdvl.com]

Mucopolysaccharidosis Type 2

Signs and symptoms of MPS 2A include: Macrocephaly Coarse facies Large rounded cheeks Thick lips Hypertrophic adenoids and tonsils Macroglossia Hoarse voice Short neck Retinal [symptoma.com]

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Umbilical hernia 0001537 5%-29% of people have these symptoms Abnormal [rarediseases.info.nih.gov]

[…] paying attention [ more ] 0000736 Sleep apnea Pauses in breathing while sleeping 0010535 Sleep-wake cycle disturbance 0006979 Splenomegaly Increased spleen size 0001744 Thick [rarediseases.info.nih.gov]

Mucopolysaccharidosis Type 1

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Thickened skin Thick skin 0001072 Tracheal stenosis Narrowing of [rarediseases.info.nih.gov]

Some of the signs and symptoms of MPS I are: Coarsening of facial features (usually the first abnormality detected at 3-6 months of age) Enlarged mouth with thick lips Enlarged [medicinenet.com]

Hypertrichotic Osteochondrodysplasia

[…] eyebrow Bushy eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Thick vermilion border Full lips Increased volume of lip Plump lips [rarediseases.info.nih.gov]

lips; Gingival hypertrophy; [Neck]; Short neck CARDIOVASCULAR: [Heart]; Cardiomegaly; Pericardial effusions; Congenital hypertrophy of left ventricle; Bicuspid aortic valve [genome.jp]

The facial gestalt included: macrocephaly, thick and bushy eyebrows, epicanthal folds, a broad nasal bridge, a bulbus nose, a long philtrum, thick lips (particularly the lower [karger.com]

Acromegaly

The facial aspect is characteristic and includes a widened and thickened nose, prominent cheekbones, forehead bulges, thick lips and marked facial lines. [orpha.net]

A person with acromegaly usually has large hands and feet, thick lips, coarse facial features, a jutting forehead and jaw, and widely spaced teeth. [hormone.org]

Aspartylglucosaminuria

lips and a square shape of face, was found to be present long before the coarsening begins. [ncbi.nlm.nih.gov]

[…] consistent dysmorphic gestalt with hypertelorism, a short and broad nose with round nares, simple often small ears with small or missing lobule and modest folding of helices, thick [ncbi.nlm.nih.gov]

Mucopolysaccharidosis

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

Physical symptoms generally include coarse or rough facial features, thick lips, an enlarged mouth and tongue, short stature with a disproportionately short trunk (dwarfism [ninds.nih.gov]

These symptoms may include kyphosis (curvature of the spine causing a “lump on the back”), joint stiffness, coarse facial features (flattened nose bridge, thick lips and an [luriechildrens.org]

Incontinentia Pigmenti Achromians

Other of her symptoms--thick lips and myopia--have been reported earlier. [pubmed.ncbi.nlm.nih.gov]

[…] lower lip vermilion Increased volume of lower lip Plump lower lip Prominent lower lip [ more ] 0000179 Showing of 58 | Last updated: 7/1/2019 Neurological problems are found [rarediseases.info.nih.gov]

0002808 Macular hypopigmented whorls, streaks, and patches 0005593 Radial deviation of finger 0009466 Somatic mosaicism 0001442 Syndactyly Webbed fingers or toes 0001159 Thick [rarediseases.info.nih.gov]

Kanzaki Disease

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Tinnitus Ringing in ears Ringing in the ears [ more ] 0000360 Percent [rarediseases.info.nih.gov]

Individuals with Schindler disease type II may also develop distinctive facial features including mildly coarse features, thick lips, a depressed nasal bridge and an enlarged [rarediseases.org]

Another patient had lymphedema, cardiomegaly, corneal opacity and slight facial coarsening including thick lips, a depressed nasal bridge and an enlarged tip of the nose. [rarediseases.info.nih.gov]

Congenital Disorder of Glycosylation Type 2M

[…] eyebrows, broad nasal bridge, thick lips, inverted nipples), variable ocular defects and brain morphological abnormalities on brain MRI (cerebral atrophy, thin corpus callosum [rarediseases.info.nih.gov]

lips, prominent cupid’s bow, protruding tongue, fused tooth, enamel hypoplasia, high-arched palate, maxillary prognathism, and retrognathia (Kodera et al., 2013; Dörre et [frontiersin.org]

[…] of glycosylation characterized by severe or profound global developmental delay, early epileptic encephalopathy, muscular hypotonia, dysmorphic features (coarse facies, thick [rarediseases.info.nih.gov]

Kahrizi Syndrome

lips. [en.wikipedia.org]

[…] syndrome characterized by severe mental retardation, cataracts with onset in late adolescence, kyphosis, contractures of large joints, bulbous nose with broad nasal bridge, and thick [mips.helmholtz-muenchen.de]

Thick lower lip vermilion MedGen UID: 326567 •Concept ID: C1839739 • Finding Increased thickness of the lower lip, leading to a prominent appearance of the lower lip. [ncbi.nlm.nih.gov]

Mucopolysaccharidosis Type 1 H/S

The early signs usually are coarsening of facial features with enlarged mouth, thick lips, and eye problems that progressively become worse. [medicinenet.com]

They also tend to look similar: Shorter than average, with stocky build Large head, bulging forehead Thick lips, widely spaced teeth, and large tongue Short, flat nose with [webmd.com]

Some of the signs and symptoms of MPS I are: Coarsening of facial features (usually the first abnormality detected at 3-6 months of age) Enlarged mouth with thick lips Enlarged [medicinenet.com]

Clark-Baraitser Syndrome

Facial manifestations include prominent supraorbital ridges, large ears, broad nasal tip, thick lower lip, and small upper lateral incisors. (Courtesy of Dr. [oxfordmedicine.com]

[…] lower lip, and microdontia of upper lateral incisors, and the mother was moderately obese. [findzebra.com]

[…] lower lip. [ghr.nlm.nih.gov]

Autosomal Recessive Hypohidrotic Ectodermal Dysplasia Type 10B

21 102100 Acromegaloid changes, cutis vertcis gyrata, and corneal leukoma (Rosenthal-Kloepfer syndrome) 22 102150 Acromegaloid facial appearance syndrome (AFA syndrome) (Thick [becomerich.lab.u-ryukyu.ac.jp]

Some people with hypohidrotic ectodermal dysplasia have distinctive facial features, including a prominent forehead, thick lips, and a flattened bridge of the nose. [ghr.nlm.nih.gov]

Palmoplantar hyperkeratosis Plantar hyperkeratosis Dysphagia Abnormality of the skeletal system Narrow forehead Hyperpigmentation of the skin Poor suck Thickened helices Thick [mendelian.co]

Dermatosparaxis

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Umbilical hernia 0001537 Wide anterior fontanel Wider-than-typical [rarediseases.info.nih.gov]

Characteristic facial appearance, sometimes called the 'Madonna face', including lobeless ears, thick nose and lips, and prominent eyes. Spontaneous pneumothorax. [patient.info]

Decreased body height Small stature [ more ] 0004322 Short toe Short toes Stubby toes [ more ] 0001831 Soft, doughy skin 0001027 Spontaneous neonatal pneumothorax 0004876 Thick [rarediseases.info.nih.gov]

Williams-Beuren Syndrome

lips, small jaw, dental anomalies, hoarse voice, strabismus, stellate iris pattern, supravalvular aortic stenosis (SVAS), pulmonary artery stenosis, mitral valve prolapse [scielo.br]

The patient had symmetric pulses, a peculiar facies, excessive periorbital subcutaneous cellular tissue, hypertelorism, saddle nose, thick lips, and wide and half-open mouth [scielo.br]

Such characteristic facial features may include a round face, full cheeks, thick lips, a large mouth that is usually held open, and a broad nasal bridge with nostrils that [rarediseases.org]

Fucosidosis

[…] eyebrow Bushy eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Thick lower lip vermilion Increased volume of lower lip Plump lower [rarediseases.info.nih.gov]

Abnormal curving of the spine 0002650 Shield chest 0000914 Short stature Decreased body height Small stature [ more ] 0004322 Splenomegaly Increased spleen size 0001744 Thick [rarediseases.info.nih.gov]

Marshall Syndrome

[…] lower lip vermilion Increased volume of lower lip Plump lower lip Prominent lower lip [ more ] 0000179 Thick upper lip vermilion Full upper lip Increased volume of upper [rarediseases.info.nih.gov]

lip Plump upper lip Prominent upper lip Thick upper lip [ more ] 0000215 Wide nasal bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of [rarediseases.info.nih.gov]

Sensorineural hearing impairment 0000407 Short nose Decreased length of nose Shortened nose [ more ] 0003196 Short stature Decreased body height Small stature [ more ] 0004322 Thick [rarediseases.info.nih.gov]

Nakajo Syndrome

The eye lids can appear rather thick or swollen with a reddish purple colour and the lips can look swollen. [printo.it]

3M Syndrome Type 2

Infants with three M syndrome have a relatively large head, triangular face, midface retrusion, thick eyebrows, fleshy nose tip, long philtrum, thick lips, and pointed chin [ncbi.nlm.nih.gov]

Relatively large head, dolichocephaly, triangular face, midface retrusion, thick eyebrows, fleshy nasal tip, long philtrum, full lips, and pointed chin. [ncbi.nlm.nih.gov]

Molybdenum Cofactor Deficiency Type B

[…] vermilion of the upper and lower lips. [ncbi.nlm.nih.gov]

[…] facial features, bitemporal narrowing, long face, prominent cheeks, widely spaced eyes, enopthalmos, frontal bossing, long palpebral fissures, long philtrum, small nose, and thick [ncbi.nlm.nih.gov]

Coffin-Lowry Syndrome

lips, a thick nasal septum with anteverted nares, and irregular or missing teeth. [ncbi.nlm.nih.gov]

[…] everted lips, and a thick nasal septum with anteverted nares. [orpha.net]

Cof·fin-Low·ry syn·drome ( kof'ĭn low'rē ), [MIM*303600] characterized by coarse facial features with bulbous nose, large ears, and thick lips; short stature; tapered fingers [medical-dictionary.thefreedictionary.com]

Immunodeficiency Type 23

Referencias Adams N, Hoehndorf R, Gkoutos G V., Hansen G, Hennig C. PIDO: the primary immunodeficiency disease ontology. Bioinformatics. 2011;27(22):3193-3199. DOI: http://dx.doi.org/10.1093/bioinformatics/btr531 [ Links ] Ameratunga R, Woon ST, Gillis D, Koopmans W, Steele R. New diagnostic criteria for common variable[…] [scielo.org.mx]

Lenz-Majewski Syndrome

lips, micrognathia), failure to thrive, mental retardation, sparse hair, enamel hypoplasia, loose skin, and skeletal abnormalities. [accessanesthesiology.mhmedical.com]

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Wide mouth Broad mouth Large mouth [ more ] 0000154 5%-29% of people [rarediseases.info.nih.gov]

Lenz-Majewski-Like Syndrome: Mesoectodermal dysplasia with macrocephaly, specific facial features (exophthalmos, broad nasal root, anteverted nostrils, large auricles, thick [accessanesthesiology.mhmedical.com]

Spondyloepimetaphyseal Dysplasia Type SPONASTRIME

[…] vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 5%-29% of people have these symptoms Cataract Clouding of the lens [rarediseases.info.nih.gov]

[…] range of motion 0005692 Kyphosis Hunched back Round back [ more ] 0002808 Muscular hypotonia Low or weak muscle tone 0001252 Scoliosis Abnormal curving of the spine 0002650 Thick [rarediseases.info.nih.gov]

Patterson Pseudoleprechaunism Syndrome

lips ... [ibis-birthdefects.org]

lips; an abnormally large mouth (macrostomia); and widely spaced eyes (hyptertelorism). [rarediseases.org]

Apostematous Glandular Cheilitis

which secrete thick saliva. [longdom.org]

[…] of a clear, thick mucus; and variable inflammation. [2] Enlargement and chronic exposure of the mucous membrane on the lower lip becomes affected by the environment, leading [rarediseases.info.nih.gov]

Thick mucoid material can be obtained by manual compression of the lip and the same can be dried on the lip surface. Rarely, this mucoid material can be purulent. [longdom.org]

Schindler Disease Type 3

Individuals with Schindler disease type II may also develop distinctive facial features including mildly coarse features, thick lips, a depressed nasal bridge and an enlarged [rarediseases.org]