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235 Possible Causes for Thick Philtrum

  • Blepharophimosis

    […] alae nasi (in younger similar to SBBYS t.) mutations in MED12 (X-linked recessive) Note blepharophimosis, swollen aspect of periorbital tissues, thick philtrum folds, thick[healthdocbox.com] Brunner) Type in contrast to the others, is characterized by X-linked inheritance and facial coarsening at older age: triangular face and the increasingly bulbous nose with thick[healthdocbox.com]

  • Goldberg-Shprintzen Syndrome

    Goldberg–Shprintzen is a condition associated with mutations in KIAA1279 gene which encodes KIF-binding protein (KBP), a protein that may interact with microtubules and actin filament. KBP may play a key role in cytoskeleton formation and neurite growth. Hirschsprung's disease may be part of the presentation.[…][en.wikipedia.org]

  • Fissured Tongue

    Tarjan et al . reported wide mouth, thick lips, long philtrum, and 90% fan-shaped positioning of anterior teeth. [7] We also found similar features in our case.[jofs.in] […] lips, long philtrum, short stature, grey hairs, telecanthus, poor in studies, hypersociable nature [Figure 1] .[jofs.in] […] hypertension of 170/70 mm of Hg, pulse rate 80/min, serum alk.phosphates-69 KAV, Cl -109 mEq/L, Ca -10.5 mg%, mild pallor, anemia with Hb-9.6 g%, typical elf-like face, wide mouth, thick[jofs.in]

  • Rabson Mendenhall Syndrome

    He had coarse facies with a short hirsute forehead, synophrys, flared nares, short philtrum, thick lips, and irregular teeth with caries.[cags.org.ae]

  • Posterior Subcapsular Cataract

    His disease was further characterized by physical underdevelopment and distinct features of hypertelorism, a wide-based nose, long philtrum, relatively large mouth with thick[ncbi.nlm.nih.gov]

  • DiGeorge Syndrome

    In the orofacial area, hypertelorism, a short philtrum, thick and reflected lips, and hypoplasia of the nasopharynx were also observed.[ncbi.nlm.nih.gov] ), blue coloring under the eyes, small outer ears, thick outer rims of the ear, two different sized ears and nasal sounding speech secondary to cleft palate.[rarediseases.org] […] fingers, small head circumference (microcephaly), recessed jaw (retrognathia), tubular nose, flat cheeks, long upper jaw, long vertical groove in the middle of the upper lip (philtrum[rarediseases.org]

  • Autosomal-Recessive Robinow Syndrome

    […] dislocation - Epicanthic folds - Euryblepharon / wide palpebral fissures - Frontal bossing / prominent forehead - Hearing loss / hypoacusia / deafness - Kyphosis - Long philtrum[csbg.cnb.csic.es] […] relapsing otitis - Cleft / notched / bifid tongue - Clitoris / labia majora / labia minora / female external genitalia hypoplasia - Depressed nasal bridge - Dysplastic / thick[csbg.cnb.csic.es] - Long / thick / curved lashes / trichomegaly / polytrichia - Low set ears / posteriorly rotated ears - Macrocephaly / macrocrania / megalocephaly / megacephaly - Micrognathia[csbg.cnb.csic.es]

  • Radioulnar Synostosis-Microcephaly-Scoliosis Syndrome

    Thick eyebrow Synophrys Pectus carinatum Abnormality of the ribs Intellectual disability Global developmental delay Premature birth Scoliosis Delayed skeletal maturation[familydiagnosis.com] […] palpebral fissure X-linked dominant inheritance Postnatal microcephaly Obsessive-compulsive behavior Nevus Abnormal cerebellum morphology Abnormal nasal morphology Short philtrum[mendelian.co] […] features may include: 2 Clinical Features of Radioulnar synostosis-microcephaly-scoliosis syndrome : Abnormality of the dentition Microcephaly Epicanthus Abnormality of the philtrum[familydiagnosis.com]

  • Trisomy 4p

    0000319 Thick eyebrow Bushy eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Wide intermamillary distance Wide-spaced nipples Widely[rarediseases.info.nih.gov] […] facial appearance Round facial shape [ more ] 0000311 Short neck Decreased length of neck 0000470 Short stature Decreased body height Small stature [ more ] 0004322 Smooth philtrum[rarediseases.info.nih.gov]

  • Fetal Disorder

    The guide reflects the full range of lip thickness and philtrum depth observed among Caucasians with Rank 3 representing the population mean.[pediatrics.aappublications.org] The guide reflects the full range of lip thickness and philtrum depth observed among African Americans with Rank 3 representing the population mean.[pediatrics.aappublications.org] The philtrum is the vertical groove between the nose and upper lip.[pediatrics.aappublications.org]

Further symptoms