Create issue ticket

101 Possible Causes for Thickened Aortic Valve, Thickening of the Mitral Valve Leaflets

  • Mucopolysaccharidosis

    Autopsy showed thickened and stenotic aortic valve leaflets as well as marked concentric intimal thickening of the aorta and muscular arteries.[] After 4 months of treatment, partial inhibition of CtsB activity in treated mice reduced aortic dilatation, as well as heart valve thickening, and led to improvements in cardiac[] Left-sided valve leaflet thickening occurred in 26 patients (five with valve disease).[]

  • Mucopolysaccharidosis 1 H-S

    […] disease with thickening and leaking of valves most commonly the mitral and aortic valves.[] Progressive thickening and stiffening of the valve leaflets can lead to mitral and aortic regurgitation, which may become hemodynamically significant in the later stages of[] Aortic regurgitation is when the aortic valve becomes thickened and allows blood to flow backward from the aorta (which is the main artery of the body) into the left ventricle[]

  • Mitral Valve Prolapse

    Similar changes were seen in the tricuspid valve. The pulmonary and aortic valves also showed myxomatous degeneration of their cusps.[] Two groups of patients were compared: those with thickening of the mitral-valve leaflets and redundancy (designated the classic form; n 319) and those without leaflet thickening[] The aortic valves were irregularly thickened along the length of the cusps primarily due to substantial expansion of the spongiosa.[]

  • Mitral Valve Stenosis

    Aortic sclerosis and stenosis: One in three elderly people have a heart murmur because of the scarring, thickening, or stiffening of their aortic valve.[] Mitral stenosis is characterized by thickening and immobility of the mitral valve leaflets.[] It is a useful non-invasive tool, which helps doctors diagnose aortic valve disease. An echocardiogram can show a thickened, calcified aortic valve which opens poorly.[]

  • Aortic Valve Disorder

    Aortic Valve, Mild Aortic Stenosis, Concentric LV Hypertrophy.[] The inflammed leaflets thicken, fuse at the edges and calcify. The resulting mitral stenosis causes pressure in the left atrium to increase.[] In people over 70, the most common cause is thickening of the valve cusps (aortic sclerosis). People may have chest tightness, feel short of breath, or faint.[]

  • Libman-Sacks Disease

    The anterior leaflet of the mitral valve was thickened.[] The 2D echo showed a decrease in aortic valve thickening and a reduction in the transvalvar doppler peak gradient to 52 mm Hg.[] Intraoperative inspection revealed thickened and fibrotic mitral valve leaflets with focal vegetations (Fig 3D,E ).[]

  • Rheumatic Aortic Valve Obstruction

    […] surface of the valve which, subsequent to aortic valvular osteoblast differentiation, calcifies. [1] Early in the disease process, the thickened aortic valve is said to be[] On two-dimensional echocardiography, rheumatic aortic valve stenosis is characterized by commissural fusion and thickening along leaflet edges.[] valves The symptoms of aortic stenosis include: Fainting Coughing Severe chest pain Heart palpitations Shortness of breath Aortic valve sclerosis is defined as the thickening[]

  • Subvalvular Aortic Stenosis

    Transthoracic echocardiography revealed a thickened aortic valve with pressure gradients and an estimated aortic valve area suggestive of mild aortic stenosis.[] In this case, the fibrous membrane adhered to the aortic valve and extended to the anterior leaflet of the mitral valve at one side.[] In both cases, the aortic valves of were thickened and also markedly narrowed on one of them.[]

  • Heart Valve Disease

    This results in generalized inflammation in the heart, this manifests in the mitral valve as vegetations, and thickening or fusion of the leaflets, leading to a severely compromised[] Parasternal long-axis echocardiogram in a patient with severe aortic stenosis. The heavily thickened aortic valve is marked with a red arrow.[] The aortic valve is the most frequently affected. This build-up hardens and thickens the valve and can cause aortic stenosis, or narrowing of the aortic valve.[]

  • Hypertrophic Cardiomyopathy

    This problem also occurs with aortic valve stenosis, in which the aortic valve becomes thickened and fails to open normally.[] […] of an anomalous papillary muscle [arrow] onto the ventricular surface of the anterior mitral leaflet).[] Other possible causes of such thickening (e.g., aortic valve stenosis, high blood pressure, among others) should be ruled out. Another option is genetic testing.[]

Further symptoms