Thickened Palms: Causes & Reasons

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Possible Causes for Thickened Palms

CHIME Syndrome

Entry H01487 Disease Name CHIME syndrome; Coloboma, congenital heart disease, ichthyosiform dermatosis, mental retardation, and ear anomalies syndrome; Zunich neuroectodermal syndrome Supergrp Inherited glycosylphosphatidylinositol deficiencies [DS:H01489] Description CHIME syndrome (coloboma, congenital heart[…] [genome.jp]

Dupuytren Contracture

Dupuytren's Contracture is a hand condition where thickening of the underlying fibrous tissues of the palm cause the fingers to bend inward. [newyorkhandsurgery.com]

Dupuytren’s Contracture is a hand condition where thickening of the underlying fibrous tissues of the palm cause the fingers to bend inward. [ypo.education]

Dupuytren’s Contracture web based movie Dupuytren’s Contracture is a hand condition where thickening of the underlying fibrous tissues of the palm cause the fingers to bend [bocacareorthopedics.com]

Diffuse Palmoplantar Keratoderma

[…] skin on palms * Thickened skin on soles Causes - Diffuse palmoplantar keratoderma- Bothnian type * Thickened skin on palms * Thickened skin on soles Prevention - Diffuse [checkorphan.org]

Abstract Palmoplantar keratoderma (PPK) is a congenital or acquired disorder characterized by the abnormal thickening of the skin of the palms and soles. [ncbi.nlm.nih.gov]

A 12-year-old female presented to the Dermatology Outpatient Department with thickening of palms and soles. [indianpediatrics.net]

Palmoplantar Keratosis

From Wikidata Jump to navigation Jump to search keratosis characterized by abnormal thickening of the palms and the soles Pajero's hand Keratosis palmaris et plantaris Palmoplantar [wikidata.org]

[…] skin on palms * Thickened skin on soles Causes - Keratosis palmoplantaris adenocarcinoma of the colon Not supplied. [checkorphan.org]

Keratoderma edit English palmoplantar keratosis keratosis characterized by abnormal thickening of the palms and the soles Pajero's hand Keratosis palmaris et plantaris Palmoplantar [wikidata.org]

Pityriasis Rubra Pilaris

[…] of the palms and soles, and opaque thickening of the nails. pityriasis rubra pilaris Etymology: Gk, pityron, bran; L, ruber red, pilus, hair a chronic inflammatory cutaneous [medical-dictionary.thefreedictionary.com]

The palms and soles thicken and have an orange colour. The nails may thicken and may be discoloured and sometimes shed. [britishskinfoundation.org.uk]

The features of the ‘circumscribed juvenile type’ are well-defined red patches with hair follicle plugs on the fronts of the knees and a yellowish thickening of the palms [skinsupport.org.uk]

Hidrotic Ectodermal Dysplasia

The phenotype in this family ranged from atrichosis to hypotrichosis, sparsity or absence of eyebrows, and thickening of palms and soles. [ncbi.nlm.nih.gov]

— A 53-year-old woman presented in our clinic with a thickening of palms and soles, hypotrichosis, and defects of the nails that had been present since infancy. [jamanetwork.com]

Pachyonychia Congenita Type 1

Overview A rare, inherited disorder characterized by thickening of nails, white patches on mouth and anus(leukoplakia) and thickened hard skin on soles and palms Symptoms [checkorphan.org]

Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles (palmoplantar hyperkeratosis or keratoderma, particularly [dermnetnz.org]

[…] that can mimic onychomycosis. 1 Our patient was referred for treatment of painful, debilitating thickenings on the palms and selected nail beds of both hands and feet that [journals.lww.com]

Pachyonychia Congenita

All nails were affected and fingernails were more thickened than toenails. Her palms and soles were normal. [ncbi.nlm.nih.gov]

Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles ( palmoplantar hyperkeratosis or keratoderma, particularly [dermnetnz.org]

A 42-year-old woman presented with complaints of rapidly progressing thickening and yellowish discoloration of the nails for the past 24 months. [ncbi.nlm.nih.gov]

Fitzsimmons-McLachlan-Gilbert Syndrome

Overview Fitzsimmons-McLachlan-Gilbert syndrome: A very rare syndrome characterized mainly by mental retardation paraplegia and thickened coarse skin on palms and soles Symptoms [checkorphan.org]

[…] coarse skin on palms and soles Symptoms * Mental retardation * Leg spasticity * High foot arch * Abnormal walk * Thickened coarse skin on palms [checkorphan.org]

Preferred Label : keratoderma, palmoplantar; MeSH definition : Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive [chu-rouen.fr]

Dilated Cardiomyopathy with Woolly Hair - Keratoderma

[…] of palms and soles 0000982 Ventricular tachycardia 0004756 Percent of people who have these symptoms is not available through HPO Autosomal recessive inheritance 0000007 [rarediseases.info.nih.gov]

Cardiac failures Heart failure [ more ] 0001635 1%-4% of people have these symptoms Death in adolescence 0011421 Death in early adulthood 0100613 Palmoplantar keratoderma Thickening [rarediseases.info.nih.gov]

Palmoplantar Keratoderma-Spastic Paralysis Syndrome

Overview A very rare syndrome characterized mainly by thickened skin on the palms and soles as well as spastic paralysis. [checkorphan.org]

Abstract Palmoplantar keratoderma (PPK) is a diverse group of disorders, characterized by thickening of the palms and soles, which are subdivided into focal or diffuse; it [degruyter.com]

Presents in infants as a honeycomb-like thickening of the skin on the palms and the soles. [firstskinfoundation.org]

Palmoplantar Keratoderma-Esophageal Carcinoma Syndrome

Palmoplantar keratodermas (PPK) comprise a heterogeneous group of keratinization disorders with hyperkeratotic thickening of palms and soles. [ncbi.nlm.nih.gov]

A 12-year-old female presented to the Dermatology Outpatient Department with thickening of palms and soles. [indianpediatrics.net]

PPK striata/areata type Hereditary painful callosities Autosomal dominant inheritance DOES NOT affect organs other than the skin Small areas of skin thickening on palms and [dermnetnz.org]

Punctate Palmoplantar Keratoderma Type 1

Symptoms include multiple tiny, hard, round bumps of thickened skin on the palms of the hands and soles of the feet. [rarediseases.info.nih.gov]

Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the palms and soles. [en.wikipedia.org]

[…] of the palms and soles. [docksci.com]

Non-Epidermolytic Palmoplantar Keratoderma

Symptoms - Thost-Unna palmoplantar keratoderma * Thickened skin on palms * Thickened skin on soles Causes - Thost-Unna palmoplantar keratoderma Not supplied. [checkorphan.org]

Exam-ination revealed diuse yellowish thickening limited tohis palms and soles, with a clear rim of erythematousdemarcation on the sides. [documents.tips]

A 12-year-old female presented to the Dermatology Outpatient Department with thickening of palms and soles. [indianpediatrics.net]

Focal Non-Epidermolytic Palmoplantar Keratoderma

PPK striata/areata type Hereditary painful callosities Autosomal dominant inheritance DO NOT affect organs other than the skin Small areas of skin thickening on palms and [dermnetnz.org]

the appearance differs to that of keratoderma with thickened velvety palms that have the appearance of tripe. [pcds.org.uk]

[…] the skin on the palms and soles. [malacards.org]

Kindler Syndrome

Other symptoms can include unusual patchy discolorations on the skin, thickened skin on the palms and feet, and atrophied or thin, dry, and wrinkled skin. [epidermolysisbullosanews.com]

In some affected individuals, the skin on the palms of the hands and soles of the feet thickens and hardens (hyperkeratosis). [ghr.nlm.nih.gov]

knees and sometimes around the fingers or toes, become thickened and overgrown and develop a rough, wart-like (verrucous) texture. [rarediseases.org]

Mal de Meleda

There was hyperhidrosis of palms and soles & a history of similar palmoplantar thickening in the paternal grandmother of the children. [ijdvl.com]

[…] of the stratum corneum of the palms and soles, with or without additional dermatologic and extracutaneous manifestations. [the-dermatologist.com]

Case 1 A 15-year-old girl presented with thickening of the skin on palms and soles from 6 months of age. [e-ijd.org]

Papillon Lefevre Disease

Cutaneous examination revealed thickening of palms and soles with fissuring encroaching to the dorsa of toes and feet, with mild localised thickening of elbows and knees. [ijdvl.com]

Presents in infants as a honeycomb-like thickening of the skin on the palms and the soles. [firstskinfoundation.org]

Papillon-Lefèvre Syndrome (PLS) is characterized by two main features: palmoplantar keratoderma (PPK) with thickening (hyperkeratosis) of the skin of palms and soles, and [genedx.com]

Epidermolytic Palmoplantar Keratoderma Type Vörner

[…] of palms and soles of affected individuals. [medicaljournals.se]

A 35-year-old patient, the mother of the patient in Case 1, had had thickening of the palms and soles since the age of 2 years. [ijdvl.com]

PPK: Also known as Vorners PPK with symmetric thickening of palms and soles with dirty snake-like skin appearance [7], [8], [9], [10] Nonepidermolytic PPK: Also known as [ijpd.in]

Pseudoainhum

At presentation, he had generalized erythema over the body with fine silvery scales [ Figure 1 ] and thickening of palms and soles. [ncbi.nlm.nih.gov]

There was symmetrical thickening of skin over both palms and soles with a yellowish discolouration (PRP sandal) (Figure 4). [jemds.com]

The nails were thickened and dystrophic with subungual hyperkeratosis. [ncbi.nlm.nih.gov]

Autosomal Recessive Pachyonychia Congenita

Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles ( palmoplantar hyperkeratosis or keratoderma, particularly [dermnetnz.org]

[…] and soles 0007410 Palmoplantar hyperkeratosis Thickening of the outer layer of the skin of the palms and soles 0000972 Palmoplantar keratoderma Thickening of palms and soles [rarediseases.info.nih.gov]

X-Linked Keratosis Follicularis Spinulosa Decalvans

[…] of palms and soles 0000982 Perifollicular fibrosis 0030054 Photophobia Extreme sensitivity of the eyes to light Light hypersensitivity [ more ] 0000613 Scarring alopecia [rarediseases.info.nih.gov]

0001041 Follicular hyperkeratosis 0007502 Folliculitis 0025084 Keratitis Corneal inflammation 0000491 Nail dysplasia Atypical nail growth 0002164 Palmoplantar keratoderma Thickening [rarediseases.info.nih.gov]

Congenital Non-Bullous Ichthyosiform Erythroderma ARCI2

[…] of palms, soles and flexures common; may have overlap with ARCI-lamellar ichthyosis type due to shared gene mutations hair: normal or sparse; abnormal-appearing hairs suggest [firstskinfoundation.org]

[…] keratodermic palms and soles, nail dystrophy with subungual hyperkeratosis. [cancertherapyadvisor.com]

Some people with NBCIE have thickening of the skin on the palms of the hands and soles of the feet (palmoplantar keratoderma), decreased or absent sweating (anhidrosis), and [ghr.nlm.nih.gov]

Epidermolysis Bullosa Simplex

In many cases these calluses form complete thickening of the palms and soles. If the thickening is severe enough it may limit the range of motion of a joint. [debra.org]

Keratolytics and softening agents for hyperkeratosis (thickening of the skin) of the palms and soles may prevent tissue from thickening and cracking. [rarediseases.info.nih.gov]

Blisters Keratoderma - Thickened skin on palms of hands and soles of feet. Confluent keratoderma in EBS-DM. [debra.org]

Lamellar Ichthyosis

palms and soles; may be fatal with complications of sepsis, protein, and electrolyte loss in the first year of life; histology shows hyperkeratosis, a prominent granular [medical-dictionary.thefreedictionary.com]

Other symptoms that may accompany this condition include, hair loss, decreased sweating, and thickened skin on the palms and soles of the feet. [patientslikeme.com]

Autosomal Recessive Congenital Ichthyosis Type 4A

[…] of palms and soles 0000982 Showing of 8 | Last updated: 5/1/2019 Making a diagnosis for a genetic or rare disease can often be challenging. [rarediseases.info.nih.gov]

Alopecia, thickening of the skin on palms and soles, and heat intolerance are common. [genedx.com]

Congenital Ichthyosiform Erythroderma

Thickened palms and soles will sometimes become secondarily infected with dermatophytes. [dermatologyadvisor.com]

Other signs and symptoms include redness of the skin (erythroderma); fine, white scales on the skin; and thickening of the skin on the palms and soles of feet (palmoplantar [rarediseases.info.nih.gov]

Acquired Ichthyosis

[…] of palms and soles 0000982 Papule 0200034 Recurrent skin infections Skin infections Skin infections, recurrent [ more ] 0001581 5%-29% of people have these symptoms Autoimmunity [rarediseases.info.nih.gov]

Pruritus Itching Itchy skin Skin itching [ more ] 0000989 30%-79% of people have these symptoms Erythema 0010783 Immunologic hypersensitivity 0100326 Palmoplantar keratoderma Thickening [rarediseases.info.nih.gov]

Knuckle Pads

AB - Epidermolytic PalmoPlantar keratoderma (EPPK) Vömer-type is an autosomal dominantly inherited skin disease, characterized by severe thickening of the palms and soles, [moh-it.pure.elsevier.com]

They may also have thickening of the skin on the palms of the hands and soles of the feet (palmoplantar keratoderma). [malacards.org]

Epidermolytic PalmoPlantar keratoderma (EPPK) Vörner-type is an autosomal dominantly inherited skin disease, characterized by severe thickening of the palms and soles, caused [pubfacts.com]

Pachyonychia Congenita Type 2

Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles ( palmoplantar hyperkeratosis or keratoderma, particularly [dermnetnz.org]

[…] and raising of the nails on the fingers and the toes and thickening of skin on the palms of the hands and the soles of the feet. [medical-dictionary.thefreedictionary.com]