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5 Possible Causes for Thickened Sternal Ends of Ribs

  • Pyle's Disease

    Pyle's disease is rare skeletal dysplasia in which a defect in metaphyseal remodeling leads to grossly widened metaphyses of long bones. Genu valgum, one of the few clinical findings in this disease, may warrant surgical intervention. Postoperative healing is documented only in Pyle's original patient. A case is presented[…][ncbi.nlm.nih.gov]

  • Mucolipidosis

    , irregular Ribs: narrow at vertebral ends, flat and broad at sternal ends Phalanges: shortened, trapezoidal in shape, widened diaphyses What is happening to the bones of[ismrd.org] Spine: anterior hypoplasia of lumber vertebrae, kyphosis Long bones: shortened, wide diaphyses, irregular metaphyses, poorly developed epiphyseal centres Clavicles: short, thickened[ismrd.org]

  • Mucolipidosis Type 4

    , irregular Ribs: narrow at vertebral ends, flat and broad at sternal ends Phalanges: shortened, trapezoidal in shape, widened diaphyses What is happening to the bones of[ismrd.org] Spine: anterior hypoplasia of lumber vertebrae, kyphosis Long bones: shortened, wide diaphyses, irregular metaphyses, poorly developed epiphyseal centres Clavicles: short, thickened[ismrd.org]

  • SAPHO Syndrome

    Ossification of the costoclavicular ligament and hyperostosis at the sternal end of the first ribs are important early findings ( Figure 1 ).[ncbi.nlm.nih.gov] Radiographs On radiographs, there is bone expansion and medullary canal stenosis, which results in diffuse thickening of the periosteum, cortex and endosteum.[ncbi.nlm.nih.gov]

  • Mucolipidosis Type 2

    , irregular Ribs: narrow at vertebral ends, flat and broad at sternal ends Phalanges: shortened, trapezoidal in shape, widened diaphyses What is happening to the bones of[ismrd.org] Spine: anterior hypoplasia of lumber vertebrae, kyphosis Long bones: shortened, wide diaphyses, irregular metaphyses, poorly developed epiphyseal centres Clavicles: short, thickened[ismrd.org]

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