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38 Possible Causes for Thickening of the Mitral Valve Leaflets, Vision Disorder

  • Mucopolysaccharidosis

    Children with the disorder may have coarse facial features, thick nostrils and lips, dwarfism, and hand deformities.[bmt.umn.edu] This disorder tends to have three main stages. During the first stage, early mental and motor skill development may be somewhat delayed.[en.wikipedia.org] Patients often have vision problems (due to clouded corneas), and severe heart problems (as the coronary artery narrows and the heart valves thicken).[bmt.umn.edu]

  • Streptococcal Infection

    Chronic rheumatic heart disease mostly affects the mitral valve, which can become thickened with calcification of the leaflets, often causing fusion of the commissures and[en.wikipedia.org] Further endocarditis can develop with aseptic vegetations along the valve closure lines, in particular the mitral valve.[en.wikipedia.org]

  • Mucopolysaccharidosis 1

    […] or hearing loss Depression Chronic Pain Shortened lifespan Prevalence / Incidence MPS I and MPS II are rare, genetic lysosomal storage disorders.[sangamo.com] Progressive thickening and stiffening of the valve leaflets can lead to mitral and aortic regurgitation, which may become hemodynamically significant in the later stages of[ncbi.nlm.nih.gov] Enzyme replacement therapy with Aldurazyme (laronidase) is designed to target the underlying cause of the disorder by replacing the missing human enzyme, alpha-L-iduronidase[biomarin.com]

  • Essential Thrombocythemia

    Echocardiography may reveal aortic and mitral valvular lesions, including leaflet thickening and vegetations, similar to those described in nonbacterial thrombotic endocarditis[medtextfree.wordpress.com] .39 The relationship of cardiac valve lesions to thromboembolic complications in essential thrombocythemia is unclear.[medtextfree.wordpress.com]

  • Mucopolysaccharidosis 1 H-S

    Corneal transplantation is possible for people with significantly reduced vision yet transplants may not always result in improved vision in the long term.[encyclopedia.com] Progressive thickening and stiffening of the valve leaflets can lead to mitral and aortic regurgitation, which may become hemodynamically significant in the later stages of[ncbi.nlm.nih.gov] Hearing, vision, breathing, heart function, joint mobility, and mental capacity may also be affected. As of 2003, seven types of MPS have been classified.[encyclopedia.com]

  • Libman-Sacks Disease

    TTE), is the best antemortum diagnostic modality for LSE established so far. 7, 8 It should be implemented when there is a high suspicion for an underlying rheumatological disorder[academic.oup.com] The anterior leaflet of the mitral valve was thickened.[ahajournals.org] Intraoperative inspection revealed thickened and fibrotic mitral valve leaflets with focal vegetations (Fig 3D,E ).[cardiothoracicsurgery.biomedcentral.com]

  • Myxoid Transformation of the Mitral Valve

    Albinos have blond hair, poor vision and severe photophobia. They are highly sensitive to sunlight.[slideshare.net] […] orifice (disorder) Systolic anterior movement of mitral valve Systolic anterior movement of mitral valve (disorder) Thickened mitral leaflet Thickened mitral leaflet (disorder[averbis.com] Mitral valve prolapse ( MVP ; a.k.a. floppy mitral valve syndrome , systolic click murmur syndrome or billowing mitral leaflet ) is a valvular heart disease characterized[en.wikipedia.org]

  • Arterial Embolism

    This results in very severe loss of vision, often resulting in no light perception. Control of modifiable risk factors is the primary prevention of this disorder.[eyewiki.aao.org] Mitral stenosis occurs due to the thickening and immobility of the mitral valve leaflets, which cause blood flow obstruction from the left atrium to the left ventricle.[dovemed.com] Primary prevention Control of modifiable risk factors is the primary prevention of this disorder.[eyewiki.aao.org]

  • Parkinson's Disease

    Olfaction and color vision identify impending neurodegeneration in rapid eye movement sleep behavior disorder. Ann Neurol. 2011;69:811–8.[doi.org] leaflets and in the mitral subvalvular apparatus, causing thickening, retraction, and stiffening of valves and resulting in incomplete leaflet coaptation and valve regurgitation[content.nejm.org] Irene Dall’Antonia, Karel Šonka and Petr Dušek, Olfaction and Colour Vision: What Can They Tell Us about Parkinson’s Disease?[doi.org]

  • Chorea

    Chorea and its disorders. Neurol Clin 2001 ; 19 : 707 –22. Lasker AG , Zee DS. Ocular motor abnormalities in Huntington’s disease. Vision Res 1997 ; 37 : 3639 –45.[pmj.bmj.com] Echocardiography evaluation showed thickened aortic and mitral valve leaflets with mild to moderate degree of mitral regurgitation.[ncbi.nlm.nih.gov]

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