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118 Possible Causes for Thickening of Tubular Membranes

  • Orchitis

    The "membranous orchitis" is characterized by thickening of tubular basement membranes, acc-mulation of macrophages and a few polymorphonuclear leukocytes, and destruction[] […] vasectomized rabbits with high levels of antibodies to sperm antigens frequently develop an orchitis associated with granular deposits of rabbit IgG and C3 in the basement membranes[]

  • Renal Impairment

    Histological findings (including glomerular and tubular basement membrane thickening, mesangial enlargement and epithelial and interstitial cell inclusions) have all been[]

  • Proteus

    Additionally, renal biopsy in hypothyroid patients showed thickening of the GBM and tubular basement membrane, increased meningeal matrix, as well as cytoplasmic inclusions[]

  • Diabetic Nephropathy

    […] intercapillary glomerulosclerosis, arteriolosclerosis, and tubular atrophy with marked tubular basement membrane thickening characteristic of advanced diabetic nephropathy[] […] of tubular basement membrane, tubular atrophy and interstitial fibrosis Isolated thickened glomerular basement membrane and proteinuria may be an early predictor of diabetic[] Pathology  Thickening of the glomerular basement membrane (GBM) is the first change that can be quantitated  Thickening of tubular basement membranes parallels this GBM[]

  • Chronic Pyelonephritis

    Alpha-antitrypsin (alpha 1AT) was always found in the sclerotic glomerular tuft (GT) and along the thickened Bowman's capsule (BC) as well as the thickened tubular basement[] membrane (TBM) in every atrophic nephron of CPN.[] Antithrombin III (AT III) was always found along the inside of thickened TBM in every atrophic nephron, but not found in the sclerotic GT nor along the thickened BC.[]

  • Acute Interstitial Nephritis

    A subsequent kidney biopsy showed irregular thickening of glomerular basement membranes (GBMs) with C4d deposition by immunohistochemistry, thickening of tubular basement[] membranes (TBMs) and diffuse interstitial inflammatory infiltrates disrupting normal kidney architecture.[]

  • Paralytic Ileus

    tubular basement membranes and inclusions in cell cytoplasm)[ 8 ].[] Primary glomerular and tubular dysfunction in hypothyroidism has also been observed with supportive histological evidence from biopsy specimens (thickening of glomerular and[]

  • Glomerulonephritis

    […] with thickening and shrinking of the tubular basal membrane, and fibrosis on 40% of the interstitial space.[] Kidney biopsy Light microscopic analysis of a specimen containing 5 glomeruli showed mesangial hypercellularity, an epithelial crescent in 1 glomerulus, tubular focal atrophy[]

  • IgG4-Related Retroperitoneal Fibrosis

    .  Tubular atrophy with thickened tubular basement membrane (TBM) and disappearance of tubules are prominent in the lesions 16.[]

  • Microangiopathy

    Histologically, DN manifests as diffuse or nodular mesangial expansion, tubular and glomerular basement membrane thickening, and interstitial fibrosis [ 3 ].[]

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