Thin Extremities: Causes & Reasons

Possible Causes for Thin Extremities

The characteristic long thin extremities and arachnodactyly usually appear during late in childhood or adolescence. [apicareonline.com]

An extremely thin or tall child is more likely to have the condition. [healthline.com]

Pituitary Cushing Syndrome

Depression (50 to 80%)1 Round face; moon face (80%)1 Thick neck (80%)1 Thin extremities (80%)1 Atrophy of skin and dermal connective tissue (70%)1 Easy bruising (50%)1 Muscle [accessphysiotherapy.mhmedical.com]

Note if the extremities are thin with atrophied muscles. [medical-dictionary.thefreedictionary.com]

The skin is thin and atrophic, with poor wound healing and easy bruising. Purple striae may appear on the abdomen. [merckmanuals.com]

Keratoglobus

[…] within the cornea cause it to become extremely thin and change to a more globular shape than its normal gradual curve Statements Identifiers Sitelinks Wikipedia (9 entries [wikidata.org]

The patient is at risk for globe perforation because the thinned out cornea is extremely weak. [ipfs.io]

Surgical treatment Further progression of the disease usually leads to a need for surgery because of extreme thinning of the cornea. [wikidoc.org]

Brittle Cornea Syndrome Type 1

Abstract Brittle cornea syndrome (BCS) is an autosomal recessive disorder characterised by extreme corneal thinning and fragility. [ncbi.nlm.nih.gov]

It is characterized by extreme thinning and fragility of the cornea that may rupture in the absence of significant trauma leading to blindness. [ncbi.nlm.nih.gov]

Penetrating keratoplasty a few months after epikeratoplasty can be performed for cases of extreme corneal thinning, and additional surgical procedures for extreme corneal [xpertdox.com]

Brittle Cornea Syndrome Type 2

Clinical Characteristics Ocular Features: Corneal thinning and extreme fragility are characteristic of BCS2. [disorders.eyes.arizona.edu]

[…] corneal thinning and fragility with rupture in the absence of significant trauma, and progression to blindness. [orpha.net]

thinning of the cornea and sclera, caused by mutations in ZNF469. [discovery.ucl.ac.uk]

Uhl Anomaly

Electrocardiographic gated multislice computed tomography (CT) showed an extremely thin walled right ventricle with almost complete absence of right ventricular free wall [heart.bmj.com]

Magnetic resonance imaging (MRI) at the age of 12-years showed an extremely dilated thin-walled right ventricle with almost complete absence of right ventricular myocardium [jstage.jst.go.jp]

Reconstructed multislice CT images in sagittal (A) and axial (B) views show the extremely thin walled right ventricle (thick arrows), normal interventricular septum (arrowheads [heart.bmj.com]

Overactive Bladder

Acupuncture practitioners treat you using extremely thin, disposable needles. [mayoclinic.org]

Spastic Tetraplegia - Thin Corpus Callosum - Progressive Postnatal Microcephaly

seizures, and brain MRI findings including thin corpus callosum, delayed myelination and cerebral atrophy. [orpha.net]

[…] global developmental delay, postnatal microcephaly and intellectual disability, which may be associated with slowly progressive spastic tetraplegia mainly affecting the lower extremities [orpha.net]

Umbilical Cord Knot

The only notable intraoperative finding was a macroscopically extremely thin umbilical cord. [ncbi.nlm.nih.gov]

Die Smulders Vles Fryns Syndrome

[…] lips and microstomia), ectomorphic habitus with extremely long, thin fingers and toes, and hypoplastic external genitalia This group of congenital disorders is extremely [dovemed.com]

[…] by extremely long, thin fingers and toes, as well as hypoplastic external genitalia. [accesspediatrics.mhmedical.com]

[…] lips and microstomia), ectomorphic habitus with extremely long, thin fingers and toes, and hypoplastic external genitalia. [dovemed.com]

Dentinogenesis Imperfecta Type 3

However, upon examination their teeth have only an extremely thin ivory layer and an enlarged pulp chamber (shell teeth). [rarediseases.org]

15q11.2 Microdeletion Syndrome

Her appearance was prominent for a narrow-shaped face with thin, brittle hair, short stature, an extremely thin habitus, deep-set eyes, and diffuse muscular atrophy. [cureus.com]

Macular Hole

It may also be preceded by a foveal detachmentcausing the fovea to become extremely thin. [touchophthalmology.com]

Fibrosis - Neurodegeneration - Cerebral Angiomatosis

Biopsy showed increased thin-walled, small dermal blood vessels with focal inter-anastamosis. [pesquisa.bvsalud.org]

Over a period of months, her findings progressed to erythematous to violaceous plaques with admixed hypopigmented stellate scarring of the bilateral lower extremities, forearms [pesquisa.bvsalud.org]

Hair Tourniquet Syndrome of Penis

Human hair which is one of the causes of PHTS is extremely thin and therefore easily coiled, especially in the presence of foreign body reaction and swelling. [sites.kowsarpub.com]

Acquired Colloid Milium

Each of these zones is extremely thin (approximately 100 μm in diameter) and 400 to 700 μm deep, producing a column of thermal damage that results in collagen denaturation [jamanetwork.com]

Thin Ribs - Tubular Bones - Dysmorphism Syndrome

The diagnosis in the fourth newborn, which showed thin long bones and clavicles and extremely thin, poorly ossified ribs, is uncertain. [link.springer.com]

extremities with reduced muscle mass, and fusions of the long tubular bones Type IV (Herva syndrome): Multiple pterygia, degeneration of the anterior horn cells of the spinal [emedicine.medscape.com]

[…] vertebrae, polyhydramnios, hypoplastic lungs and heart, and diaphragmatic hernia Type III (van Regemorter syndrome): Multiple pterygia, pulmonary hypoplasia, facial anomalies, thin [emedicine.medscape.com]

Conn's Adenoma

Physical Examination Findings Cushing's syndrome Physical exam should include body morphology, as central obesity with thin extremities is common. [cancertherapyadvisor.com]

Patients with Cushing’s syndrome caused by a hypersecretory adenoma usually have central obesity with thin extremities and weight gain is almost always present. [cancertherapyadvisor.com]

Patients with lipodystrophy (i.e., patients receiving antiretroviral therapy) may have thin extremities and central obesity but should lack the biochemical abnormalities. [cancertherapyadvisor.com]

Acrogeria

It's not so much wrinkling, as I do not see that feature, but the extremely thin skin on the hands (tops and palms) and feet (tops). [inspire.com]

It is thin and extremely fragile. Veins are prominent and distinctive under the skin of the affected children because of the lack of fat tissue. [epainassist.com]

The skin over the distal third of all four extremities was extremely thin and wrinkled with loss of subcutaneous fat and prominent dilated veins [Figs. 3 and 4]. [ncbi.nlm.nih.gov]

ACTH-Independent Cushing Syndrome

In addition to the unique patterns of fat deposition, Cushing syndrome patients have thin extremities (spider appearance) that are due to the effects of cortisol on protein [themedicalbiochemistrypage.org]

extremities, decreased bone density (especially spine), kyphosis and back pain (secondary to bone loss), easy bruising and poor wound healing due to thin and atrophic skin [physio-pedia.com]

extremities and central obesity, buffalo hump. [aippg.net]

Glycogen Storage Disease Type 1C

Affected children typically have doll-like faces with fat cheeks, relatively thin extremities, short stature, and protuberant abdomen. [ncbi.nlm.nih.gov]

In addition, patients have thin extremities, a short stature, and protuberant abdomens (due to the severe hepatomegaly). [themedicalbiochemistrypage.org]

ACTH-Dependent Cushing Syndrome

There’s increased breakdown of most types of tissue leads to muscle wasting and thin extremities, skin thinning, easy bruising and abdominal striae or lines, bone thinning [osmosis.org]

It causes characteristic symptoms including obesity of the trunk and thinning of the extremities, a thickening at the base of neck called a buffalo hump, a rounding of the [surgery.med.miami.edu]

Ehlers-Danlos Syndrome Arthrochalasia Type 1

Patients with a rare but very serious subtype, vEDS display a range of symptoms such as thin skin with visible blood vessels, especially in chest and lower extremities. [news-medical.net]

Van Allen-Myhre Syndrome

He presented with respiratory distress and an extremely thin abdominal wall with bulged out intra-abdominal organs. [ijdvl.com]

The second case was a 4-month-old female child (born to non-consanguineous parents) who presented with an extremely thin membranous lower abdominal Figure 1: Images of the [cyberleninka.org]

thin membranous lower abdominal wall below the umbilicus. [ijdvl.com]

Adrenal Cushing Syndrome

Symptoms: Moon face (round, red, and full) Weight gain Buffalo hump (a collection of fat between the shoulders) Central obesity with protruding abdomen and thin extremities [uclahealth.org]

It causes characteristic symptoms including obesity of the trunk and thinning of the extremities, a thickening at the base of neck called a buffalo hump, a rounding of the [surgery.med.miami.edu]

Signs and symptoms of Cushing syndrome include: truncal obesity with thin extremities “buffalo hump” edema of the lower extremities (from sodium and fluid retention) osteoporosis [americannursetoday.com]

Nakajo Syndrome

The combination of muscle and fat loss worsens over time, leading to an extremely thin (emaciated) appearance in the face, chest, and arms. [encyclopedia.pub]

This leads to an extremely thin (emaciated) appearance in the face, chest, and arms.[4] Other symptoms of Nakajo-Nishimura syndrome are enlarged liver and spleen (hepatosplenomegaly [en.wikipedia.org]

Anorexia

In a society that lives by sayings like “You can’t be too rich or too thin,” extreme dieting is usually applauded. [futuresofpalmbeach.com]

It's no secret that anorexia causes extreme thinness, but many of the other signs are much more subtle, according to Marisa Sherry, MS, RD, a New York-based nutritionist who [cbsnews.com]

Anorexia nervosa, more commonly known as anorexia, is both an eating disorder and a metabolic condition that results in excessive weight-loss and extreme thinness caused by [psycom.net]

Tricho-Dento-Osseous Syndrome

Enamel alteration in people with TDO ranges from being extremely thin and/or rough and pitted to being of normal color and only slightly decreased thickness. [stjoeslitreview.blogspot.com]

[…] and/or possibly pitted enamel, that is malformed. the teeth can also look normal in color, but also have a physical impression of extreme fragility and thinness in appearance [icd.codes]

[…] curly hair Thin hair Hair fall Premature emergence of teeth Discoloration of teeth Extremely brittle nails The signs and symptoms of Tricho-Dento-Osseous Syndrome-III (TDO-III [dovemed.com]

Mulibrey Nanism Syndrome

It is characterized by pre- and postnatal growth restriction, relative macrocephaly, thin extremities and typical craniofacial features (scaphocephaly, facial triangularity [orpha.net]

In addition, practically all patients were gracile and had thin extremities. [jmg.bmj.com]

Nearly all the patients were gracile with relative macrocephaly, and thin extremities with proximal relative shortness and narrow shoulder (fig 2). [jmg.bmj.com]

Anterior Pituitary Hypofunction

Obese trunk with thin extremities. B. Assess skin—color and texture. Florid facies. Red striae of skin stretched with fat tissue. Fragile skin, easily bruised. C. [brilliantnurse.com]

A truly hypofunctioning anterior pituitary gland can cause many serious disturbances: extreme thinness, growth failure, sexual aberration, and intolerance for normal variations [faqs.org]

Assess for thin extremities. J. Assess for hypertension. K. Evaluate electrolyte imbalance. Potassium depletion. Sodium and water retention. Metabolic alkalosis. L. [brilliantnurse.com]