Thin Eyebrows: Causes & Reasons

Possible Causes for Thin Eyebrows

Limited hair on end of eyebrow 0005338 Swelling of proximal interphalangeal joints Swelling of innermost hinge joints 0006253 Thin eyebrow Thin eyebrows 0045074 Thin nail [rarediseases.info.nih.gov]

Spoon shaped White spots Hair Sparse Thin Slow growing Thin eyebrows Neurological Low muscle tone in infancy (hypotonia) Normal intelligence Voice Deep Diagnosing Trichorhinophalangeal [nfed.org]

Spoon shaped White spots Hair Sparse Thin Slow growing Thin eyebrows Neurological Low muscle tone in infancy (hypotonia) Normal intelligence Voice Deep Diagnosing TRPS1 is [nfed.org]

Kaufman Oculocerebrofacial Syndrome

eyebrow Thin eyebrows 0045074 Thin vermilion border Decreased volume of lip Thin lips [ more ] 0000233 Wide mouth Broad mouth Large mouth [ more ] 0000154 5%-29% of people [rarediseases.info.nih.gov]

eyebrows - Blepharophimosis / short palpebral fissures - Complete / partial microdontia - Epicanthic folds - Failure to thrive / difficulties for feeding in infancy / growth [csbg.cnb.csic.es]

eyebrow Not very common - Between 30% and 50% cases Fine hair Commonly - More than 50% cases Thin skin Not very common - Between 30% and 50% cases Short palpebral fissure [mendelian.co]

Hypergonadotropic Hypogonadism - Partial Alopecia

eyebrow 33 frequent (33%) HP:0000535 32 hearing impairment 60 33 occasional (7.5%) Occasional (29-5%) HP:0000365 33 triphalangeal thumb 60 33 occasional (7.5%) Occasional [malacards.org]

absence of breast tissue, absent ovaries, mild-moderate dorsal kyphosis, thin upper lip and unilateral sensorioneural deafness in one of them. [ncbi.nlm.nih.gov]

mineralization defects of the skull, thin dysplastic clavicles, pulmonary hypoplasia, multiple joint contractures and an early neonatal lethal course. [ab-y-ss.com]

Cornelia De Lange Syndrome

Typical facial features include: Thin eyebrows that meet in the middle Long eyelashes A short upturned nose Thin downturned lips Learn more about the physical characteristics [gemssforschools.org]

Secondary Characteristics of CdLS Facial Features Prominent facial features include thin eyebrows that often meet at the midline (synophrys), long eyelashes, short upturned [cdlsusa.org]

[…] nose, thin downturned lips, low-set ears, and high-arched palate or cleft palate. [cdlsusa.org]

Odonto-Onycho-Dermal Dysplasia

Hypotrichosis / atrichia / atrichiasis / scalp hairlessness - Palmoplantar hyperkeratosis / keratoderma - Tooth shape anomaly - Urticaria Frequent - Absent / decreased / thin [csbg.cnb.csic.es]

eyebrow Thin, sparse eyebrows 0000535 Sparse body hair 0002231 Sparse scalp hair Scalp hair, thinning Sparse, thin scalp hair sparse-absent scalp hair [ more ] 0002209 Percent [rarediseases.info.nih.gov]

Some patients may have dry, thin hair and sparse eyebrows, and may have a smooth tongue with missing taste buds. [sema4.com]

Hidrotic Ectodermal Dysplasia

eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 5%-29% of people have these symptoms Abnormal nasolacrimal [rarediseases.info.nih.gov]

Physical examination revealed severely dystrophic nails and thin scalp hair, fine eyebrows and eyelashes and thin body hair. [panafrican-med-journal.com]

Eyebrows are thin or absent. Teeth are usually normal. Treatment: Genetic counseling is indicated. [skincareguide.ca]

Nestor-Guillermo Progeria Syndrome

eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Spotty hyperpigmentation Spotty increased pigmentation [rarediseases.info.nih.gov]

eyebrow ; Sparse eyelashes ; Spotty hyperpigmentation ; Wide cranial sutures Associated Genes BANF1 (Withdrawn symbols: BAF ) Mouse Orthologs Banf1 (Withdrawn symbols: C78287 [mousephenotype.org]

eyebrow Very Common - Between 80% and 100% cases Insulin resistance Very Common - Between 80% and 100% cases Other less frequent symptoms Patients with BANF1 gene alterations [mendelian.co]

Tricho-Rhino-Phalangeal Syndrome

Spoon shaped White spots Hair Sparse Thin Slow growing Thin eyebrows Neurological Low muscle tone in infancy (hypotonia) Normal intelligence Voice Deep Diagnosing TRPS1 is [nfed.org]

He has alopecia and thin lateral eyebrows. Typical bone deformities include short, deformed fingers (right, here shown in the mother). [movementdisorders.org]

Chromosome 19q13.11 Deletion Syndrome

eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Sporadic No previous family history 0003745 Wide nasal [rarediseases.info.nih.gov]

Dysmorphologic evaluation revealed: narrow face, thick medially sparse eyebrows, hypertelorism, columella below alae nasi, thin lips, retrognathia, low set ears with large [nature.com]

/dry skin + + + + + - - + 6/8 Thin-sparse hair + + + + + - + - - + 7/10 Thin-sparse eyebrows/eyelashes + + + + + + + + - - + 9/11 Teeth abnormalities + g + h - + i + j - + [molecularcytogenetics.biomedcentral.com]

Rothmund-Thomson Syndrome

Associated symptoms are alterations in the teeth, sparse hair, thin eyebrows, lack of eyelashes, low stature, bone abnormalities, hematological illnesses, gastrointestinal [cun.es]

[…] and soles 0000972 Scoliosis 0002650 Short philtrum 0000322 Small for gestational age Birth weight less than 10th percentile Low birth weight [ more ] 0001518 Sparse and thin [rarediseases.info.nih.gov]

Ehlers-Danlos Syndrome Spondylodysplastic Type 1

eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Sparse scalp hair Reduced/lack of hair on scalp Scalp [rarediseases.info.nih.gov]

Features that are unique to this type include short stature ; bowing of the legs; weak muscle tone; sparse scalp hair and eyebrows; soft, doughy skin; and thin, translucent [rarediseases.info.nih.gov]

curly hair; sparse eyebrows and eyelashes Joint contractures and hypermobility Loose, elastic skin on the face The former name for spondylodysplastic Ehlers-Danlos syndrome [rarediseases.info.nih.gov]

Spondyloepiphyseal Dysplasia with Congenital Joint Dislocations

Fixed elbow flexion MedGen UID: 870595 •Concept ID: C4025044 • Finding Sparse and thin eyebrow MedGen UID: 924309 •Concept ID: C4282407 • Finding Decreased density/number [ncbi.nlm.nih.gov]

KID Syndrome

eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Squamous cell carcinoma 0002860 Trichiasis Ingrown [rarediseases.info.nih.gov]

[…] dystrophy Poor nail formation 0008404 Pes cavus High-arched foot 0001761 Recurrent corneal erosions Recurrent breakdown of clear protective layer of eye 0000495 Sparse and thin [rarediseases.info.nih.gov]

Tricho-Rhino-Phalangeal Syndrome Type 3

eyebrow, Sparse hair 115,604,739(-) C/T coding_sequence_variant, stop_gained rs1057518972 syndrome 3 (TRPS3) [MIM:190351], likely-pathogenic, pathogenic, Alopecia areata, [genecards.org]

Protruding ear ; Scoliosis ; Short distal phalanx of finger ; Short metacarpal ; Short metatarsal ; Short stature ; Shortening of all phalanges of fingers ; Sparse and thin [mousephenotype.org]

Zlotogora-Ogur Syndrome

[…] palm - Syndactyly of toes Frequent - Abnormal dentition / dental position / implantation / unerupted / dental ankylosis - Abnormally placed nipples - Absent / decreased / thin [csbg.cnb.csic.es]

eyebrow Hypohidrosis Wide intermamillary distance Oral cleft Cleft upper lip Finger syndactyly Hyperlordosis Cleft lip Hypogonadotrophic hypogonadism Toe syndactyly Peripheral [mendelian.co]

eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Showing of 52 | Last updated: 2/1/2021 Find a Specialist [rarediseases.info.nih.gov]

Pitt-Hopkins-Like Syndrome Type 1

Individuals with Pitt-Hopkins syndrome have distinctive facial features that include thin eyebrows, sunken eyes, a prominent nose with a high nasal bridge, a pronounced double [encyclopedia.pub]

PTHS phenotype is described including craniofacial dysmorphism with brachycephaly, biparietal narrowing, wide nasal bridge, thin and linear lateral eyebrows, palpebral edema [mdpi.com]

[…] lateral eyebrows, specific nose conformation with a broad nasal bridge, ridge and a bulbous tip with flared nasal alae, full cheeks/prominent midface, and wide mouth/full [mdpi.com]

Ectodermal Dysplasia with Natal Teeth Type Turnpenny

eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Sparse scalp hair Scalp hair, thinning Sparse, thin [rarediseases.info.nih.gov]

Hemangioma Retinal dystrophy Sparse eyebrow Sparse and thin eyebrow Small nail Carious teeth Carcinoma Nevus Posterior fossa cyst Tubulointerstitial nephritis Scaphocephaly [mendelian.co]

0000677 Relative macrocephaly Relatively large head 0004482 Short stature Decreased body height Small stature [ more ] 0004322 Slow-growing scalp hair 0100038 Sparse and thin [rarediseases.info.nih.gov]

Odonto-Onycho Dysplasia with Alopecia

brittle, slow-growing scalp hair, fair and sparse eyebrows and eyelashes, absent axillary and pubic hair, fragile and brittle fingernails, thick and brittle toenails (both [orpha.net]

[…] syndrome Disease definition Odonto-onycho dysplasia-alopecia syndrome is a rare, genetic ectodermal dysplasia syndrome characterized by almost total alopecia with only sparse, thin [orpha.net]

Fibular Dimelia-Diplopodia Syndrome

[…] anomalies Absent/decreased/thin eyebrows Darker than expected eyebrows Flared eyebrows High arched eyebrows Lateral thinning of eyebrows Synophris/synophrys Thick/bushy eyebrows [readbag.com]

[…] blindness/amblyopia Vitreous anomalies/hyalitis/persistent vitreous vascularisation Xerophthalmia/dry eyes www.orphanet.net/ 4 of 39 Thesaurus of Clinical Signs and Symptoms Eyebrows [readbag.com]

2q37 Microdeletion Syndrome

highly arched eyebrows, depressed nasal bridge, full cheeks, deficient nasal alae and prominent columella, thin upper lip, and various minor anomalies of the pinnae.[4] [en.wikipedia.org]

[…] and upturned eyebrows, posteriorly rotated ears, flat nasal bridge, low hanging columella, thin upper lip, downturned corners of mouth and breast hypertelorism. [bmcpediatr.biomedcentral.com]

She exhibited a flat nasal bridge, deep-set eyes, arched eyebrows, and a thin upper lip as well as abnormalities of both ears. [e-apem.org]

Microphthalmia - Ankyloblepharon - Intellectual Disability Syndrome

eyebrow Lipodystrophy Melanocytic nevus Abnormality of dental enamel Venous thrombosis Small for gestational age Microcornea Small hand Irregular hyperpigmentation Lymphedema [mendelian.co]

eyebrow Fine hair Encephalocele Joint hypermobility Inability to walk Oligohydramnios Congenital visual impairment Hypertonia Atrial septal defect Intellectual disability [mendelian.co]

Narrow face Short phalanx of finger X-linked dominant inheritance Prominent nose Short metacarpal Prominent nasal bridge Visual loss Blindness Visual impairment Sparse and thin [mendelian.co]

Ichthyosis and Male Hypogonadism

[…] fingers Absent eyebrows Sparse eyebrows Glaucoma Undescended testes Small penis Hypothyroidy Small teeth Peripheral retinal pigmentary changes Sparse scalp hair Absent scalp [checkorphan.org]

eyebrow Erysipelas Ventriculomegaly Dermal atrophy Hydrocephalus Hyporeflexia Dilatation Cerebellar hypoplasia Coloboma Severe global developmental delay Corneal opacity [mendelian.co]

[…] hypogonadism includes the 24 symptoms listed below: Scaly skin Pituitary gonadotropic hormone deficiency Secondary hypogonadism Delayed puberty Seizures Short stature Long thin [checkorphan.org]

Coffin-Siris Syndrome 8

Dysmorphic features may or may not be present and include hypertrichosis or thin scalp hair, thick eyebrows, thin upper vermilion, and upturned nose (Machol et al., 2019). [malacards.org]

Abnormality of head or neck Anteverted nares Sparse scalp hair Thick eyebrow Thick lower lip vermilion Thin upper lip vermilion Abnormality of the digestive system Feeding [ncbi.nlm.nih.gov]

thin upper lip vermilion, and upturned nose. [malacards.org]

Pitt-Hopkins Syndrome

Facial dysmorphism - Enophthalmos, thin eyebrows, a large beaked nose with flared nostrils, broad cup-shaped ears, a fleshy and Cupid's bow appearance of the upper lip, a [symptoma.com]

The distinctive facial features in individuals with Pitt-Hopkins syndrome include the following: Thin eyebrows Sunken eyes Prominent nose with a high nasal bridge Exceptionally [patientworthy.com]

Individuals with Pitt-Hopkins syndrome have distinctive facial features that include thin eyebrows, sunken eyes, a prominent nose with a high nasal bridge, a pronounced double [encyclopedia.pub]

Trichodysplasia - Xeroderma Syndrome

Diseases related with Carcinoma and Sparse and thin eyebrow In the following list you will find some of the most common rare diseases related to Carcinoma and Sparse and thin [mendelian.co]

Symptoms List: Trichodysplasia-xeroderma syndrome Symptoms and clinical features may include: 1 Clinical Features of Trichodysplasia-xeroderma syndrome : Sparse and thin eyebrow [familydiagnosis.com]

eyebrow 33 hallmark (90%) HP:0000535 9 alopecia 60 33 frequent (33%) Frequent (79-30%) HP:0001596 10 sparse body hair 60 33 frequent (33%) Frequent (79-30%) HP:0002231 11 [malacards.org]

PLP1-Related Disorder

PHIP patients show distinct facial features that can be recognizable such as large ears, thick eyebrows, upturned nose and thin lips. [docslib.org]

Calderon Gonzalez Cantu Syndrome

Pili torti Flattened and twisted hair 0003777 Sparse and thin eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more [rarediseases.info.nih.gov]

60 Very frequent (99-80%) 12 pili torti 60 Very frequent (99-80%) 13 sparse and thin eyebrow 33 HP:0000535 Symptoms via clinical synopsis from OMIM: 58 Skin: photosensitivity [malacards.org]

[…] hair shaft Thin hair texture [ more ] 0002213 Intellectual disability Mental deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 [rarediseases.info.nih.gov]

X-Linked Keratosis Follicularis Spinulosa Decalvans

eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 X-linked inheritance 0001417 X-linked recessive inheritance [rarediseases.info.nih.gov]

Perifollicular fibrosis 0030054 Photophobia Extreme sensitivity of the eyes to light Light hypersensitivity [ more ] 0000613 Scarring alopecia of scalp 0004552 Sparse and thin [rarediseases.info.nih.gov]

Bainbridge-Ropers Syndrome

eyebrows, hypertelorism, downslanting palpebral fissures, long, tubular nose with broad tip and prominent nasal bridge and wide mouth with full, everted lower lip. [globalgenes.org]

The facial phenotype included prominent forehead, hypertelorism, high anterior hairline, thin eyebrows, mild synophrys, anteverted nostrils with hypoplastic alae nasi, high-arched [elsevier.es]

Her stature was thin, her fingers long and slender. [nature.com]

Blepharophimosis - Intellectual Disability Syndrome Type Verloes

eyebrow Thin, sparse eyebrows 0000535 Stenosis of the external auditory canal Narrowing of passageway from outer ear to middle ear 0000402 Thin vermilion border Decreased [rarediseases.info.nih.gov]

[…] upper lip vermilion Anxiety Attention deficit hyperactivity disorder Oligodontia Conjunctivitis Thick eyebrow Microphallus Ventriculomegaly Hydrocephalus Agenesis of corpus [mendelian.co]

eyebrow, Telecanthus, Delayed peripheral myelination, Synophrys, Mi... [mousephenotype.org]