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2 Possible Causes for tillonen

  • Metronidazole

    PubChem Compound 4173 PDB ID 2MN ChEBI ID 6909 ReferencesSynthesis Reference Not Available Material Safety Data Sheet (MSDS) Download (PDF) General References Visapaa JP, Tillonen[] Ann Pharmacother. 2000 Feb;34(2):255-7. [ PubMed:10676835 ] Visapaa JP, Tillonen JS, Kaihovaara PS, Salaspuro MP: Lack of disulfiram-like reaction with metronidazole and ethanol[]

  • Disulfiram-like Reaction

    Tillonen J, Vakevainen S, Salaspuro V, et al. Metronidazole increases intracolonic but not peripheral blood acetaldehyde in chronic ethanol-treated rats.[] Tillonen et al conducted a study indicating that this reaction might involve ADH inhibition in the gastrointestinal (GI) tract, instead of in the liver as previously thought[]

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