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3,220 Possible Causes for transmembrane

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  • Influenza

    Recent studies suggested, the rs12252 T   C polymorphism in the interferon-inducible transmembrane protein 3 (IFITM3) gene might be associated with susceptibility to severe[]

  • Otitis Media

    Chemokine CXC receptor 4 (CXCR4) is a 352-amino acid seven-span transmembrane G-protein coupled receptor, essential for inflammatory response.[] KEYWORDS: aquaporin; human middle ear; otitis media; transmembrane permeability; water channel[]

  • Tuberculosis

    Polymorphisms in some genes, for example in NRAMP1 gene which encodes the NRAMP1 transmembrane protein that pumps divalent ions out of lysosomes, may result in ineffectual[]

  • Hendra Virus

    Hendra virus F transmembrane domain (TMD) residues S490 and Y498 were found to be important for correct Hendra virus F recycling, with the hydroxyl group of S490 and the aromatic[] Abstract While work with viral fusion proteins has demonstrated that the transmembrane domain (TMD) can affect protein folding, stability, and membrane fusion promotion, the[] Mutations to the F protein transmembrane domain or cytoplasmic tail that disrupted endocytic trafficking led to failure of F to function with M for VLP assembly.[]

  • Urticarial Vasculitis

    Rituximab is a monoclonal antibody against CD20 transmembrane protein on the surface of mature and malignant B cells.[]

  • Pelizaeus-Merzbacher Disease

    In mouse oligodendroglial cells, mutant isoforms of PLP/DM20 with fewer than all four transmembrane (TM) domains are fully ER retained.[] As this change results in a Thr-to-Pro change at amino acid 181 in a region of the gene predicted to be part of a transmembrane segment, it was concluded that this was the[] Exclusion of exon 6 does not alter the reading frame but leads to absence of amino acids 232-253 that constitute a main part of the fourth transmembrane helix of the PLP protein[]

  • Ranitidine

    It is postulated that GPCR activation involves the movement of transmembrane helices.[] […] that many residues, which have been shown to be critical for receptor activation and are highly conserved among different GPCRs, are clustered in particular positions of transmembrane[]

  • Essential Tremor

    The aim of this study was to determine the frequency and spectrum of variations in teneurin transmembrane protein 4 in a cohort of Canadian essential tremor cases.[] METHODS: The coding portion of teneurin transmembrane protein 4 was sequenced in 269 unrelated essential tremor cases and 288 matched control individuals using a targeted[] CONCLUSIONS: Our results do not support a positive association between teneurin transmembrane protein 4 and the Canadian population. 2017 International Parkinson and Movement[]

  • Chronic Bronchitis

    KEYWORDS: chronic bronchitis; chronic obstructive pulmonary disease; cystic fibrosis transmembrane conductance regulator[] Abstract Cigarette smoking causes acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction and is associated with delayed mucociliary clearance and[] There is growing evidence that these diseases may have parallels in disease pathogenesis as well, including cystic fibrosis transmembrane conductance regulator dysfunction[]

  • Antiarrhythmic Agent

    We recorded transmembrane action potential (TAP) characteristics at different stimulation frequencies (0.5, 1, 1.5, and 2 Hz) and with different dosages of ambasilide (1,[] Using transmembrane microelectrode recording techniques, we demonstrated that H 234/09 markedly prolonged the action potential duration (APD) without affecting the maximal[]

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