Trophoblastic Cells: Causes & Reasons

Possible Causes for Trophoblastic Cells

These results suggest that these cells exhibit characteristics of trophoblastic cells, especially cytotrophoblastic cells. [ncbi.nlm.nih.gov]

Hydatidiform mole (molar pregnancy) is a benign tumor of placental trophoblastic cells, which release human chorionic gonadotropin (hCG). [ncbi.nlm.nih.gov]

Furthermore, we discovered miR-21 was significantly increased in JAR and JEG-3 cells compared with normal primary human trophoblastic cells. [ncbi.nlm.nih.gov]

Choriocarcinoma

cell lines. [ncbi.nlm.nih.gov]

Furthermore, we discovered miR-21 was significantly increased in JAR and JEG-3 cells compared with normal primary human trophoblastic cells. [ncbi.nlm.nih.gov]

Cell apoptosis serves a role in the progression from hydatidiform mole to persistent gestational trophoblastic disease. [ncbi.nlm.nih.gov]

Invasive Hydatidiform Mole

(βhCG) Rare Epithelioid trophoblastic tumor (ETT) Chorionic-type extravillous trophoblastic cells in the chorion laeve Variant of PSTT – clinical behavior similar to PSTT [arupconsult.com]

Sheets of anaplastic trophoblastic cells are noted without the maintenance of the pattern of the villi. Extensive necrosis is evident. Back to Top [glowm.com]

General Information About Gestational Trophoblastic Disease Gestational trophoblastic disease (GTD) is a group of rare diseases in which abnormal trophoblast cells grow inside [northshore.org]

Testicular Embryonal Carcinoma

Abstract Hyperglycosylated human chorionic gonadotropin (hCG-H), a variant of hCG, has been shown to promote the growth and invasion of trophoblast cells in early pregnancy [digitalrepository.unm.edu]

[…] teratoma (91023) Embryonal carcinoma (90703; also called embryonal cell carcinoma—poorer prognosis) Teratocarcinoma (90813; a combination of teratoma and embryonal carcinoma [training.seer.cancer.gov]

Trophoblastic Tumor (e.g. [fpnotebook.com]

Chorioamnionitis

DC-SIGN-positive cells were increased in the chorioamniotic mesodermal layer of CCA cases. [ncbi.nlm.nih.gov]

[…] disease/Gebelikte trofoblastik hastalık249Giant cell tumor/Dev hücreli tümör76Gonadotropin/Gonadotropin143Gynecologic oncology/Jinekolojik onkoloji255Gynecologic tumor/Jinekolojik [tjoddergisi.org]

Macrophages in the chorionic trophoblastic layer of CCA cases were characterized by CD68 positivity. [ncbi.nlm.nih.gov]

Therapeutic Abortion

Of 180 women who underwent therapeutic abortion in a certain period in 1977, 71.7% were unmarried and 63.9% were unmarried primigravidas. At the first follow-up visit 3 to 6 weeks postabortion 55.0% of the unmarried primigravidas chose oral contraceptives and 43.2% chose intrauterine devices (IUDs). Of the unmarried[…] [ncbi.nlm.nih.gov]

Testicular Choriocarcinoma

Choriocarcinoma is a malignant growth of trophoblastic cells characterized by secretion of human chorionic gonadotropin. [ncbi.nlm.nih.gov]

Choriocarcinoma, a malignancy of trophoblastic cells, is characterized by the secretion of human chorionic gonadotropin (hCG). [ncbi.nlm.nih.gov]

cells Syncytio-trophoblastic cells Abundant syncytio-trophoblasts Syncytio-trophoblasts hCG+ Molecular / cytogenetics description Board review question #1 Which biomarker [pathologyoutlines.com]

Gestational Trophoblastic Neoplasm

Gestational trophoblastic disease (GTD) is an umbrella term for a group of rare diseases in which abnormal trophoblast cells grow inside the uterus after conception. [cancercenter.com]

A gestational disorder characterized by an abnormal placenta with marked enlargement of the chorionic villi and hyperplasia of the villous trophoblastic cells. [icd9data.com]

Both types of IT cells develop from a population of trophoblastic cells in the trophoblastic columns that we have tentatively termed "villous IT cells." [pathology.jhu.edu]

Malignant Placental Neoplasm

NKH-1, a monoclonal antibody to natural killer cells, reacted with both molar and placental villous trophoblast and with two choriocarcinoma cell lines. [ncbi.nlm.nih.gov]

cells. [codes.iarc.fr]

Choriocarcinoma is a highly malignant neoplasm resulting from the malignant transformation of proliferating trophoblastic cells and the molecular mechanisms leading to this [ncbi.nlm.nih.gov]

Placental Cyst

Subsequent histological and biochemical examinations seem to prove their origin from the trophoblastic «X-cells» and confirm their frequent benign nature. [moh-it.pure.elsevier.com]

cells Back to top [pathologyoutlines.com]

Ashley Moffett and colleagues describe the generation of long-term, genetically stable organoid cultures of specialist trophoblast cells derived from first trimester human [natureasia.com]

Gestational Trophoblastic Disease

Ultrasound may be helpful in differentiating epithelioid trophoblastic tumor from placental-site trophoblastic tumor, another tumor of intermediate trophoblastic cells, which [ncbi.nlm.nih.gov]

The trophoblastic cells were generally bland. However, a subset of trophoblastic cells showed large, hyperchromatic nuclei in some areas. [ncbi.nlm.nih.gov]

During fertilization, trophoblastic cells invade the endometrium, blood vessels and myometrium to establish fetomaternal circulation. [oncolex.org]

Complete Hydatidiform Mole

These results suggest that these cells exhibit characteristics of trophoblastic cells, especially cytotrophoblastic cells. [ncbi.nlm.nih.gov]

A gestational disorder characterized by an abnormal placenta with marked enlargement of the chorionic villi and hyperplasia of the villous trophoblastic cells. [icd9data.com]

Microscopic examination demonstrated hydropic degeneration of all the chorionic villi with trophoblastic cell proliferation consistent with a complete hydatidiform mole. [ncbi.nlm.nih.gov]

Placental-Site Trophoblastic Tumor

This case illustrates that tumor cells resembling intermediate trophoblastic cells may metastasize to regional retroperitoneal lymph nodes. [ncbi.nlm.nih.gov]

Samples collected from uterus at the autopsy revealed large trophoblastic cells with eosinophilic cytoplasm. [ncbi.nlm.nih.gov]

IST-2 cells were highly motile and invasive in culture as compared to choriocarcinoma JEG-3 cells and normal extravillous trophoblastic cells. [ncbi.nlm.nih.gov]

Epithelioid Trophoblastic Tumor

Immunostaining showed that these tumor cells had a lower Ki67 index than choriocarcinoma, and epithelioid trophoblastic cell tumor although they exhibited an epithelioid trophoblastic [ncbi.nlm.nih.gov]

ETT originates from the intermediate trophoblastic cells of chorion laeve. [ncbi.nlm.nih.gov]

Trophoblastic Neoplasm

OBJECTIVE: To evaluate the role of p27Kip1 in tumorigenesis and the development of trophoblastic cell disease. [ncbi.nlm.nih.gov]

PSTT develops from neoplastic transformation of presumable trophoblastic stem cell and assumes a differentiation toward a specific type of trophoblastic cells, called intermediate [link.springer.com]

The cells resemble the trophoblastic cells in the chorion laeve, and we have therefore designated them "chorionic-type intermediate trophoblast." [ncbi.nlm.nih.gov]

Placenta Succenturiata

These two functions are fulfilled by different specialized trophoblast cell subtypes, and my laboratory has been studying how their formation and functions are regulated during [ncbi.nlm.nih.gov]

[…] by the trophoblastic cells. [intechopen.com]

syncytiotrophoblast cells, extravillous trophoblast cells, decidual cells and blood vessels. [web.archive.org]

Placental Disorder

Considering the key function of activin A on trophoblast cell behaviors and placenta development, we proposed miR-195 may affect trophoblast cell invasion by repressing the [journals.lww.com]

PHDs were mainly expressed in syncytiotrophoblast leaf cells and trophoblast cells with PHD-1 mRNA specifically highly expressing in extravillous trophoblast cells (Figure [ijbs.com]

The decidua, the most superficial layer from the maternal side (top), comprises maternal uterine and immune cells, as well as specialized glycogen-storing cells from the trophoblast [nature.com]

Leaking Abdominal Aortic Aneurysm

[…] and trophoblast cells. [scholar.google.com.cu]

Todeschini, E Fulcheri, PL Venturini Gynecologic oncology 84 (2), 280-284, 2002 100 2002 Regulatory role of NKp44, NKp46, DNAM-1 and NKG2D receptors in the interaction between NK cells [scholar.google.com.cu]

Adhesion of Amnion to Fetus

Instead, the blood comes into direct contact with the embryonic trophoblast cells. [study.com]

[…] mononuclear cells) ⑦ Trophoblast cells further differentiate into villous and extravillous trophoblast Villous trophoblast cells give rise to chorionic villi and are responsible [pathophys.org]

Trophoblast cells are an exception, producing instead their own unique histocompatibility antigen. [education.med.nyu.edu]

Intratubular Embryonal Carcinoma

Expression for p63 is seen in mononucleated trophoblast cells in choriocarcinoma. p63 is negative in embryonal carcinoma. [pathologyoutlines.com]

Carbon Monoxide -- Teratogenic Agent

The movement of drugs across the placenta is limited by a single layer of cell called trophoblasts. 3 Factors controlling placental drug transfer 1. [slideplayer.com]

Hydatidiform Mole 2

After fertilisation, some cells from the fertilised ovum (called the trophoblast cells) develop into the placenta and membranes that form around the developing baby. [patient.info]

cells. [icd10data.com]

The trophoblast cells grow and develop as a disorganised mass of tissue but the embryo does not develop. This is a complete hydatidiform mole. [patient.info]

Preeclampsia

The MHC status of trophoblast cells is a crucial factor to be considered, as these molecules can act as ligands for uterine immune cells, including T cells, NK cells and myelomonocytic [ncbi.nlm.nih.gov]

These findings obtained suggest that preeclampsia develops upon increased macrophage activity, leading to destruction of the placenta trophoblast cells. [ncbi.nlm.nih.gov]

Herein we summarize the current findings regarding the expression of placental miRNAs and their function, especially in the trophoblast cells. [ncbi.nlm.nih.gov]

Glandular-Alveolar Pattern Testicular Yolk Sac Tumor

cells, formed by the abnormal proliferation of cuboidal and syncytial cells of the placental epithelium, without the production of chorionic villi. 1, record 96, English, [btb.termiumplus.gc.ca]

[…] chorioepithelioma 1, record 96, English, chorioepithelioma Record 96, Textual support, English Record number: 96, Textual support number: 1 DEF An epithelial malignancy of trophoblastic [btb.termiumplus.gc.ca]

SALL4-Related Disorders

In a trophoblastic component of a testicular germ cell tumor, small trophoblasts are positive but the larger cells including syncytiotrophoblasts are negative. D. [pubmed.ncbi.nlm.nih.gov]

SALL4 was consistently expressed in all germ cell tumors except some trophoblastic tumors and mature components of teratomas, in which it was selectively expressed in intestinal-like [pubmed.ncbi.nlm.nih.gov]

In adult tissues, it was only detected in germ cells. [pubmed.ncbi.nlm.nih.gov]

Placentitis

Extravillous trophoblast cells migrate into the decidua and remodel uterine arteries. [ncbi.nlm.nih.gov]

To investigate the expression of ICAM-1 by villous trophoblasts, its relationship with rupture of the trophoblastic barrier and influx of immune cells into the villi, we analysed [ncbi.nlm.nih.gov]

Cytomegalovirus infection of trophoblast cells elicits an inflammatory response: a possible mechanism of placental dysfunction. Am J Obstet Gynecol 2006;194:535-41. [medigraphic.com]

Placental Infarction

Total numbers of cells were also seen to be markedly decreased, placental membrane showed 51% decrease in trophoblastic mass or cellular content. [oapublishinglondon.com]

The positive cytoplasmic immunohistochemical staining for human placental lactogen identified these cells as trophoblasts and the whole necrotic tissue fragment as a placental [circ.ahajournals.org]

transforms to the trophoblastic cell mass that intermixes with endometrial cells (10th postovulatory day). [radiologykey.com]

DNMT1-Related Disorder

Therefore, changes in DNAm measured in com-and term (n = 19) human placental samples of four cell populations: trophoblasts, Hofbauer cells, endothelial cells,and stromal [open.library.ubc.ca]

Single-cell RNA-seqreveals the diversity of trophoblast subtypes and patterns of differentiationin the human placenta. Cell Res. 2018:819–32.34. [open.library.ubc.ca]

Here, we present the first methylome-wide analysis of first trimester (n = 9) and term (n = 19) human placental samples of four cell populations: trophoblasts, Hofbauer cells [open.library.ubc.ca]

Mosaic Trisomy 21

In mitotic CPM the trisomic cell line arises from postzygotic mitotic duplication of one chromosome in the progenitors of a placental cell lineage (either trophoblast or extra [fn.bmj.com]

Additionally, both placental cell lineages, trophoblast as well as chorionic stroma, should be analysed before excluding a diagnosis of CPM. [fn.bmj.com]

(A) Mitotic CPM arises from a diploid zygote when a postzygotic error occurs in one of the placental cell lineages (trophoblast or mesenchymal stroma). [fn.bmj.com]

Uterine Corpus Adenomatoid Tumor

cell invasion with the occurrence of tubal pregnancy. [search.bvsalud.org]

The expression of Talin1 in the fallopian tube and chorionic villi is significantly increased in women with tubal pregnancy, suggesting the association of Talin1-regulated trophoblast [search.bvsalud.org]

[…] cell invasion (P < 0.01) and migration (P < 0.05), down-regulated the expression of N-cadherin, MMP-2 and Snail (P < 0.05), and up-regulated the expression of MMP-9 in the cells [search.bvsalud.org]