Truncal Ataxia: Causes & Reasons

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Possible Causes for Truncal Ataxia

Opsoclonus-Myoclonus Syndrome

Opsoclonus, myoclonus, and truncal ataxia were noted. [ncbi.nlm.nih.gov]

A 69 year-old man developed sudden-onset multidirectional, constant, involuntary ocular movements associated with vertigo, truncal ataxia and involuntary movements of the [ncbi.nlm.nih.gov]

Two weeks after treatment with intravenous immunoglobulin and corticosteroids, her opsoclonus, myoclonus, and truncal ataxia disappeared. [ncbi.nlm.nih.gov]

Cerebellar Ataxia

Midline lesions can produce severe gait and truncal ataxia. [patient.info]

hypotonia and cerebellar dysfunction (nystagmus, ataxic gait, truncal ataxia, dysarthric speech and intention tremor), associated with cerebellar hypoplasia. [orpha.net]

For instance, damage to the midline cerebellar structures induces gait and truncal ataxia, while damage to the unilateral cerebellar hemisphere causes ipsilateral limb cerebellar [frontiersin.org]

Spinocerebellar Ataxia Type 1

Neurological examination 5 years after onset revealed slow eye movement with nystagmus as well as limb and truncal ataxia. [ncbi.nlm.nih.gov]

They may fall to the side of the lesion NOTE: patients with disease of the vermis and flocculonodular lobe will be unable to stand at all as they will have truncal ataxia–they [stanfordmedicine25.stanford.edu]

ataxia Instability or lack of coordination of central trunk muscles 0002078 Urinary bladder sphincter dysfunction 0002839 Showing of 65 | Last updated: 6/1/2019 Making a [rarediseases.info.nih.gov]

Dandy-Walker Syndrome

ataxia. [slideshare.net]

ataxia Instability or lack of coordination of central trunk muscles 0002078 Showing of 19 | Last updated: 1/1/2020 In most cases, the exact cause of Dandy-Walker complex [rarediseases.info.nih.gov]

[…] and ataxia, truncal. [malacards.org]

Friedreich Ataxia

The clinical picture consisted of progressive spastic gait, truncal and limb ataxia, dysarthria, nystagmus, hyperreflexia with knee and ankle clonus and extensor plantar response [ncbi.nlm.nih.gov]

Ataxia (truncal and limb), lower extremity weakness, and sensory loss is progressive and gradually extends from distal to proximal [6] [8]. [physio-pedia.com]

Truncal ataxia results in swaying on sitting and may necessitate back support. [medcraveonline.com]

Subacute Sclerosing Panencephalitis

He had varicella-like illness with vesicular, itchy truncal rash erupting one month prior to the onset of these symptoms. [ncbi.nlm.nih.gov]

A 5-year-old boy presented with acute-onset cerebellar ataxia without associated encephalopathy, focal motor deficits, seizures or cognitive decline. [ncbi.nlm.nih.gov]

Progressive Myoclonic Epilepsy Type 3

ataxia * Loss of fine finger movement Causes * Dysarthria * Mental retardation * Truncal ataxia. [checkorphan.org]

ataxia * Loss of fine finger movement Causes - Epilepsy progressive myoclonic type 3 * Dysarthria * Mental retardation * Truncal ataxia. [checkorphan.org]

Other features include mental retardation, dysarthria, truncal ataxia, and loss of fine finger movements. [malacards.org]

Olivopontocerebellar Atrophy

This report concerns an unusual form of olivopontocerebellar atrophy (OPCA) of adult onset, inherited as an autosomal dominant. We examined 5 patients in one generation and performed neuropathological investigations in 3 of these. The clinical and pathological features were different from those of OPCA types I to[…] [ncbi.nlm.nih.gov]

Acute Cerebellar Ataxia

This patient developed symptoms of ACA, including nausea, vertigo, severe limb and truncal ataxia, and bilateral spontaneous continuous horizontal nystagmus with irregular [ncbi.nlm.nih.gov]

In addition to his marked truncal ataxia and wide-based, staggering gait, he had slowness of speech, which is not commonly reported with this condition in the literature. [ncbi.nlm.nih.gov]

Abstract Acute Cerebellar Ataxia (ACA) is not infrequent disorder in childhood characterized by sudden onset of such cerebellar signs as truncal ataxia, dysmetria, tremors [ncbi.nlm.nih.gov]

Alcoholic Cerebellar Degeneration

ataxia Unsteady gait Nystagmus May be clinically asymptomatic in some individuals Laboratory No specific laboratory abnormalities Radiology description Atrophy of the anterior [pathologyoutlines.com]

Midline lesions can produce severe gait and truncal ataxia. [patient.info]

A 41 yo female with slow progressive ataxia, slurred speech since last 15 years. Truncal ataxia on neurological examination. [neuroradiologycases.com]

Primary Torsion Dystonia

Abstract A GAG deletion in the DYT1 gene accounts for most early, limb onset primary torsion dystonia (PTD). The genetic bases for the more common adult onset and focal PTD are less well delineated. Genetic loci for an "intermediate dystonia" phenotype and for torticollis, named DYT6 and DYT7 respectively, have[…] [ncbi.nlm.nih.gov]

Autosomal Recessive Spinocerebellar Ataxia 18

truncal. [malacards.org]

ataxia. [synapse.koreamed.org]

On neurological examination, the child had moderate truncal ataxia, dysarthria but no tremor and pyramidal signs in the lower limbs. [ojrd.biomedcentral.com]

Spastic Ataxia with Congenital Miosis

Midline lesions can produce severe gait and truncal ataxia. [patient.info]

Clinical features from OMIM: 108650 UMLS symptoms related to Spastic Ataxia 7, Autosomal Dominant: ataxia, gait ataxia, dysdiadochokinesis, ataxia, truncal, muscle spasticity [malacards.org]

Clinical examination at age 13 years showed truncal and gait ataxia, small-amplitude... [findzebra.com]

Cerebellar Mass Lesion

[…] cord — > gait abnormalities Truncal Ataxia versus Appendicular Ataxia Truncal Ataxia Caused by lesions confined to the cerebellar vermis Affect primarily the medial motor [brainaacn.org]

This will be due to ataxia involving the lower extremities (not the truncal ataxia with vermis lesions (see below). [casemed.case.edu]

Diagnosis Case: Spinocerebellar ataxia = slowed degeneration of the nerves Chronic Localize: 1) Dysmetria bilateral -> bilateral cerebellar hemispheres 2) Truncal ataxia - [quizlet.com]

X-Linked Spinocerebellar Ataxia Type 5

The ataxia initialy begins as purely truncal but later on, within several years peripheral coordination also get involved. [explainmedicine.com]

A degenerative process in the midline cerebellum can thus result in the following findings: Gait ataxia (especially difficulty with tandem gait) Imbalance Truncal ataxia Dysmetria [clinicaladvisor.com]

Typical clinical signs and symptoms of autosomal dominant ataxias (ADCA) include the following: Limb and truncal ataxia Hyperreflexia and spasticity (pyramidal signs) are [centogene.com]

Subacute Cerebellar Degeneration

Midline lesions can produce severe gait and truncal ataxia. [patient.info]

Marked truncal ataxia with inability to stand without support was observed. Gait however was narrow based with reeling to either side. [annalsofian.org]

The typical clinical features include subacute (weeks to few months) cerebellar ataxia, though rarely, the course can be acute or insidious. [3], [4] Gait and truncal ataxia [neurologyindia.com]

Dysequilibrium Syndrome

Dysequilibrium syndrome (DES) is a non-progressive congenital ataxia characterized by severe intellectual deficit, truncal ataxia and markedly delayed, quadrupedal or absent [ncbi.nlm.nih.gov]

ataxia was used to identify the mutation. [ncbi.nlm.nih.gov]

An 18-month-old girl presented with significant hypotonia, global developmental delay, and truncal and peripheral ataxia. [ncbi.nlm.nih.gov]

Muscular Dystrophy-Dystroglycanopathy Type C7

ataxia syndrome autosomal recessive limb-girdle muscular dystrophy type 2e muscular dystrophy, limb-girdle, type 2y muscular dystrophy, limb-girdle, type 2w autosomal recessive [genecards.org]

ataxia syndrome Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome Intellectual disability-hypotonia-spasticity-sleep disorder syndrome Intellectual [se-atlas.de]

[…] limb-girdle, type 2y muscular dystrophy, limb-girdle, type 2e muscular dystrophy, limb-girdle, type 2a calpainopathy 26322222 intellectual disability-hyperkinetic movement-truncal [genecards.org]

Cerebellar Ataxia with Peripheral Neuropathy Type 2

The vermis is concerned with midline and truncal position and receives input from the spinal cord. Dysfunction is noted by postural instability and gait ataxia. [medexam.net]

ATAXIA “errors in the RATE, RANGE, FORCE & DIRECTION of movement” •GAIT ATAXIA •TRUNCAL ATAXIA •LIMB ATAXIA 16. [slideshare.net]

Ataxia-Oculomotor Apraxia Syndrome

Subsequently, he suffered from arms dysmetria, truncal ataxia and cerebellar dysarthric speech. He was wheelchair bound by the age of 23-years. [cags.org.ae]

Other signs include: Truncal ataxia Oculomotor apraxia Decreased tendon reflexes Pulmonary infections Sinus infections Bulbar dysfunction Recurrent aspiration Gonadal atrophy [patient.info]

Infantile-onset autosomal recessive nonprogressive cerebellar ataxia Intellectual disability-hyperkinetic movement-truncal ataxia syndrome Isolated dystonia Joubert syndrome [se-atlas.de]

Hereditary Cerebellar Degeneration

This is another indication of appendicular ataxia. Tests for Truncal Ataxia Truncal ataxia presents as an unsteady gait. [kenhub.com]

Though truncal ataxia and gait speed on SARA were sustained at 12 weeks, there was no continued decrease in the number of falls. [movementdisorders.org]

Cerebellar Stroke

Midline lesions can produce severe gait and truncal ataxia. [patient.info]

The following symptoms are roughly in descending order of incidence: Headache of abrupt onset Nausea and vomiting Inability to walk (reflecting truncal ataxia) Dizziness, [emedicine.medscape.com]

Ask the patient to sit up with arms crossed - looking for truncal ataxia. Ask the patient to walk heel-to-toe (to elicit any gait ataxia). [patient.info]

Autosomal Recessive Spinocerebellar Ataxia Type 17

[…] the extremities, truncal ataxia, increased reflexes in the lower extremities, and intellectual disability. [malacards.org]

TGM6 gene Spinocerebellar ataxia (SCA36) OMIM #614153 Truncal instability Dysarthria Dysdiadochokinesis Hyperreflexia Impaired smooth pursuit and horizontal gaze nystagmus [emedicine.medscape.com]

Limb and truncal ataxia and seizures may be present. [movementdisorders.org]

Wiedemann-Rautenstrauch Syndrome

Clinical features can involve the central nervous system (CNS) (psychomotor development deficiency, hypotonia, truncal ataxia, intention tremor, and nystagmus), head and neck [accesspediatrics.mhmedical.com]

truncal. [malacards.org]

Progeroid Syndrome, Neonatal, also known as wiedemann-rautenstrauch syndrome, is related to marfan lipodystrophy syndrome, and has symptoms including action tremor and ataxia [malacards.org]

Diomedi-Bernardi-Placidi Syndrome

May have ocular or genital abnormalities PQBP1, Xp11.3 Rett syndrome XLMR in girls, cessation and regression of development in early childhood, truncal ataxia, autistic features [pediatrics.aappublications.org]

Older patients have limb and truncal ataxia and experience frequent falls. [disorders.eyes.arizona.edu]

ataxia, ophthalmoplegia, mutism, incontinence, hypoplasia of the cerebellum, and brain stem SLC9A6, Xq26 Coffin–Lowry syndrome Short stature, distinctive facies, large soft [pediatrics.aappublications.org]

Autosomal Recessive Spinocerebellar Ataxia

SCAR16 is characterized by truncal and limb ataxia resulting in gait instability. [uniprot.org]

Typical clinical signs and symptoms of autosomal dominant ataxias (ADCA) include the following: Limb and truncal ataxia Hyperreflexia and spasticity (pyramidal signs) are [centogene.com]

Ataxia, both truncal and cerebellar, is present. Mobility is impaired from early childhood and eventually requires assistance. [disorders.eyes.arizona.edu]

Parenchymatous Cortical Cerebellar Degeneration

Mild truncal ataxia was observed, but there was no nystagmus. [ajnrblog.org]

21 Older adult: SCA 6, 35, 36 ; 37 Childhood: SCA 2, 7, 13, 27, DRPLA, 25 Anticipation Some SCA: 1, 2, 3, 6, 7, 8, 10, 12, 17, 22, DRPLA More prominent in SCA 7 & DRPLA Ataxia [neuromuscular.wustl.edu]

Truncal: SCA 1 ; 2 ; 6 ; 14 ; 28 ; 31 ; 36 Tremor Head or Hand: SCA 8, 12, 15-16, 19, 27 Palatal: SCA 20 Normal lifespan: SCA 6, 11 Eye 60 Slow saccades Early/prominent: [neuromuscular.wustl.edu]

Usher Syndrome Type 3B

Truncal ataxia Ear malformation Hearing impairment [ncbi.nlm.nih.gov]

[…] motor development Photophobia Truncal ataxia Ear malformation Hearing impairment IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies [ncbi.nlm.nih.gov]

ataxia and wide-based gait Normal peripheral nerve function Charcot-Marie-Tooth disease Progressive peripheral neuropathy (motor and sensory) Variable severity and onset [gene.vision]

Wernicke Encephalopathy

A few days later, her consciousness and limb ataxia began to improve. However, truncal ataxia and polyneuropathy became evident. [ncbi.nlm.nih.gov]

Cerebellar testing in bed with finger-to-nose and heel-to-shin tests may not illicit any notable deficit; thus, it is important to test for truncal ataxia with the patient [emedicine.medscape.com]

Truncal ataxia was present, even though limb coordination was intact. Tone, power, and reflexes were normal. Her laboratory investigations are presented in [Table 1]. [neurologyindia.com]

Progressive Myoclonic Epilepsy Type 8

The patient presented truncal ataxia, tremor in both hands that could be increased voluntarily, dysarthria, and bilateral dysmetria (finger-to-nose test). [elsevier.es]

Neurological exam disclosed dysarthria, truncal and appendicular ataxia, bilateral horizonto‐torsional nystagmus, choreoatethoic movements in his fingers, slight dystonic [onlinelibrary.wiley.com]

Not described Not described Not described Not described Truncal and appendicular ataxia Gait impairement Wheelchair‐bound Unable to walk without support Not described Not [onlinelibrary.wiley.com]