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30 Possible Causes for Two-Three Toe Syndactyly

  • Dubowitz Syndrome

    Skeletal issues can be delayed bone age, fifth finger clinodactyly , two/three toe syndactyly , and pes planus . Some are very prone to eczema or have severe allergies.[dubowitzsyndrome.net] Skeletal issues can be delayed bone age, fifth finger clinodactyly , two/three toe syndactyly, and pes planus. Some are very prone to eczema or have severe allergies.[ric.edu]

  • Young Adult-Onset Distal Hereditary Motor Neuropathy

    […] to three toe syndactyly, and hypogenitalism.[frontiersin.org] […] with characteristic peculiar facial appearance, cleft palate, microcephaly, hypotonia, cardiac defects, prenatal and postnatal growth retardation, postaxial polydactyly, two[frontiersin.org]

  • Cardiodysrhythmic Potassium-Sensitive Periodic Paralysis

    Skeletal findings include mild syndactyly of toes two and three as well as fifth-digit clinodactyly.[ncbi.nlm.nih.gov] […] of the following: Low-set ears Widely spaced eyes Small mandible Fifth-digit clinodactyly Syndactyly of toes 2 and 3 B.[ncbi.nlm.nih.gov] One of the above three criteria AND at least one other family member who meets two of the three criteria [ Statland et al 2018 ] Supportive Findings Individuals with either[ncbi.nlm.nih.gov]

  • Long QT Syndrome 8

    syndactyly of toes two and three.[ncbi.nlm.nih.gov] Syndactyly. Cutaneous syndactyly of the fingers and cutaneous syndactyly of toes two and three can both be seen in numerous disorders.[ncbi.nlm.nih.gov] […] or bilateral cutaneous syndactyly variably involving fingers two (index), three (middle), four (ring), and five (little) and bilateral cutaneous syndactyly of toes two and[ncbi.nlm.nih.gov]

  • Smith Lemli Opitz Syndrome

    (two-to-three toe syndactyly).[doi.org] […] of toes two-three bilaterally suggested SLOS.[ncbi.nlm.nih.gov] Clinical manifestations include dysmorphic facial features, mental retardation and limb defects including cutaneous two to three toe syndactyly ( 3, 4 ).[doi.org]

  • Congenital Malformation of the Tricuspid Valve

    - to three-toe syndactyly, cleft palate, lung anomalies, genital anomalies X-linked Recessive Simpson-Golabi-Behmel syndrome 25 ASD; VSD; rare, variable cardiomyopathy Macrosomia[pedsinreview.aappublications.org] […] distal digital hypoplasia Keutel syndrome 70 (P)PS Short digits, mixed hearing loss, cartilage calcification Smith-Lemli-Opitz syndrome 45 ASD, VSD, complete AVSD, TAPVC Two[pedsinreview.aappublications.org]

  • Micrognathism

    toe syndactyly; Pes planusSKIN, NAILS, HAIR: [Skin]; Eczema (face and flexural areas); Sacral dimple; [Hair]; Sparse scalp hairNEUROLOGIC: [Central nervous system]; Mental[findzebra.com] External genitalia, male]; Hypospadias; Inguinal hernia; [Internal genitalia, male]; CryptorchidismSKELETAL: Delayed bone age; [Hands]; Fifth finger clinodactyly; [Feet]; Two-three[findzebra.com]

  • Syndactyly

    […] involving three adjacent toes.[podiatrytoday.com] There are two distinct forms. The most common form is duplication of the distal phalanx of the fifth toe and syndactyly with the fourth toe.[podiatrytoday.com] It is also important to keep in mind that the surgeon should never attempt desyndactyly or any intervention on both sides of a toe in those cases of syndactyly and polysyndactyly[podiatrytoday.com]

  • Congenital Heart Disease

    - to three-toe syndactyly, cleft palate, lung anomalies, genital anomalies X-linked Recessive Simpson-Golabi-Behmel syndrome 25 ASD; VSD; rare, variable cardiomyopathy Macrosomia[pedsinreview.aappublications.org] […] distal digital hypoplasia Keutel syndrome 70 (P)PS Short digits, mixed hearing loss, cartilage calcification Smith-Lemli-Opitz syndrome 45 ASD, VSD, complete AVSD, TAPVC Two[pedsinreview.aappublications.org]

  • Kleiner Holmes Syndrome

    […] involving three adjacent toes.[podiatrytoday.com] There are two distinct forms. The most common form is duplication of the distal phalanx of the fifth toe and syndactyly with the fourth toe.[podiatrytoday.com] It is also important to keep in mind that the surgeon should never attempt desyndactyly or any intervention on both sides of a toe in those cases of syndactyly and polysyndactyly[podiatrytoday.com]

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