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4,758 Possible Causes for tyrosine

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  • Idiopathic Pulmonary Fibrosis

    Targeting non-malignant disorders with tyrosine kinase inhibitors. Nat Rev Drug Discov 2010 ;9: 956 - 970 9. Chaudhary NI, Roth GJ, Hilberg F, et al.[doi.org] KEYWORDS: Anti-fibrotic drugs; idiopathic pulmonary fibrosis; nintedanib; tyrosine kinase inhibition[ncbi.nlm.nih.gov] […] previously unrecognized and unreported case of a patient with anti-glomerular basement membrane glomerulonephritis following nintedanib, an orally active small molecule tyrosine[ncbi.nlm.nih.gov]

  • Pneumonia

    We investigated whether a more efficient reduction in oxidative stress, mirrored by a lowering of Tyrosine, and an increase in Tyr-NO2 and the Tyrosine/Tyr-NO2 ratio was associated[ncbi.nlm.nih.gov] RATIONALE: Echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), a distinct molecular entity, is highly sensitive to ALK tyrosine kinase[ncbi.nlm.nih.gov] As an adaptive response, cells catabolize Tyrosine to 3-Nitrotyrosine (Tyr-NO2) by nitrosylation.[ncbi.nlm.nih.gov]

  • Osteoporosis

    PubMed Central PubMed Google Scholar Kim WK, Bae KH, Choi HR, Kim DH, Choi KS, Cho YS, Kim HD, Park SG, Park BC, Ko Y, Lee SC: Leukocyte common antigen-related (LAR) tyrosine[doi.org] […] downregulation of COL4A1, COL4A2, and COL4A4 Focal adhesion signaling [ 79 ] Osteoblast differentiation in MC3T3-E1 preosteoblast cells/ leukocyte common antigen-related tyrosine[doi.org]

  • Infectious Mononucleosis

    The addition of free gp350 to primary B cells leads to CD19 tyrosine phosphorylation and the subsequent recruitment of the phosphatidylinositol 3-kinase ( 41 ).[dx.doi.org]

  • Adrenal Insufficiency

    The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22 gene) predisposes to autoimmune Addison's disease. Clin Endocrinol (Oxf) . 2008 Aug 15.[emedicine.medscape.com]

  • Meningitis

    Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling. Immunol.[ncbi.nlm.nih.gov] Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling. Immunol. Rev. 203 : 200 -215. Lloyd, M.[doi.org] Bruton's tyrosine kinase expression and activity in X-linked agammaglobulinaemia (XLA): the use of protein analysis as a diagnostic indicator of XLA. Clin. Exp.[ncbi.nlm.nih.gov]

  • Tuberculosis

    Imatinib-sensitive tyrosine kinases regulate mycobacterial pathogenesis and represent therapeutic targets gainst tuberculosis.[dx.doi.org] Imatinib-sensitive tyrosine kinases regulate mycobacterial pathogenesis and represent therapeutic targets gainst tuberculosis .[ncbi.nlm.nih.gov] Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H -ATPase to inhibit phagosome acidification. Proc. Natl. Acad. Sci.[doi.org]

  • Tyrosinemia

    RESULTS: All patients presented with high tyrosine concentrations in CSF correlating with increased plasma tyrosine levels and a reduced CSF serotonin turnover.[ncbi.nlm.nih.gov] The disease results from deficiency in hepatic tyrosine aminotransferase (TAT; L-tyrosine:2-oxoglutarate aminotransferase, EC 2.6.1.5), a 454-amino acid protein encoded by[ncbi.nlm.nih.gov] Abstract Tyrosinemia II is an autosomal-recessively inherited condition caused by deficiency in the liver-specific enzyme tyrosine aminotransferase (TAT; EC 2.6.1.5).[ncbi.nlm.nih.gov]

  • Tyrosine Increased

    Solubilization and partial purification of tyrosine hydroxylase from bovine adrenal medulla. J. Biol. ‎ Seite 14 - (1966).[books.google.de] Thus, another phosphatase may be overactive, perhaps dephosphorylating a regulatory (inhibitory) site on a protein tyrosine kinase, accounting for the abnormal PMN tyrosine[ncbi.nlm.nih.gov] Metabolic Disorders and Newborn Screening Invitae Elevated Tyrosine Panel Test description The Invitae Elevated Tyrosine Panel analyzes FAH , TAT , and HPD , three genes that[invitae.com]

  • Chronic Myeloid Leukemia

    Inhibitors of Abl tyrosine kinase are divided into two main groups, namely, ATP-competitive and ATP non-competitive inhibitors.[doi.org] Imatinib mesylate, Abl tyrosine kinase inhibitor, has improved the treatment of Bcr-Abl-positive leukemia such as chronic myeloid leukemia (CML) and Philadelphia chromosome[ncbi.nlm.nih.gov] Tyrosine Kinase Inhibitors Class Summary Tyrosine kinase inhibitors elicit strong inhibition of tyrosine kinase activity of the BCR/ABL abnormality in all phases of CML.[emedicine.medscape.com]

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