Unilateral Proptosis: Causes & Reasons

Possible Causes for Unilateral Proptosis

A 44-year-old man presented with unilateral proptosis and progressively deteriorating vision of his left eye over a 2-week period. [ncbi.nlm.nih.gov]

An otherwise asymptomatic 63-year-old woman with a history of a carcinoid tumor of the ileum and a cutaneous melanoma of the shoulder developed unilateral proptosis. [ncbi.nlm.nih.gov]

Four patients presented with recent onset of unilateral proptosis, 1 patient presented with inflammatory manifestations, and 1 patient presented with unilateral ptosis. [ncbi.nlm.nih.gov]

Orbital Neoplasm

Symptoms Orbital tumors typically present with early unilateral proptosis of the globe and may adversely affect visual and extraocular muscle function. [skullbaseinstitute.com]

Orbital metastases may be unilateral/bilateral and usually present with abrupt proptosis associated with a superior orbital mass. Prognosis is very poor. [patient.info]

An aching discomfort, typically associated with unilateral proptosis, is an important part of the clinical presentation. [aao.org]

Congenital Exophthalmos

CLASSIFICATION Proptosis can be divided into following clinical groups: Unilateral proptosis Bilateral proptosis Acute proptosis Intermittent proptosis Pulsating proptosis [ikeyes.blogspot.com]

It presents with acute, usually unilateral proptosis with severe pain. [oculoplastic-eyelid-orbit-surgery.com]

Unilateral proptosis in adults is also most frequently caused by TED. [aao.org]

Orbital Rhabdomyosarcoma

Orbital rhabdomyosarcoma is the most common orbital malignancy of childhood with the common presentation of rapidly evolving unilateral proptosis. [ncbi.nlm.nih.gov]

Abstract A 68-year-old female who had undergone treatment several years previously for breast cancer presented with diplopia and unilateral proptosis and exposure keratopathy [ncbi.nlm.nih.gov]

Material and methods A total of 148 cases of unilateral proptosis of neoplastic origin were examined. [ijo.in]

Exophthalmos

In our study, we found 13% of patients presenting unilateral TED with the appearance of unilateral proptosis. [bmcophthalmol.biomedcentral.com]

Acute unilateral proptosis suggests infection or vascular disorder (eg, hemorrhage, fistula, cavernous sinus thrombosis). Chronic unilateral proptosis suggests tumor. [merckmanuals.com]

CT or MRI of the orbits is often useful to confirm the diagnosis and to identify structural causes of unilateral proptosis. [msdmanuals.com]

Orbital Lymphoma

proptosis and diverse features due to diffuse involvement of cranial vault and brain parenchyma. [3] Our present case had unilateral proptosis and diffuse involvement of [cancerjournal.net]

Signs and symptoms of Graves' ophthalmopathy, such as unilateral or bilateral proptosis, double vision, limitation of movement of the extraocular muscles, are not specific [ncbi.nlm.nih.gov]

proptosis in adults) References Hasegawa M, Kojima M, Shioya M, Tamaki Y, Saitoh J, Sakurai H, Kitamoto Y, Suzuki Y, Niibe H, Nakano T. [webeye.ophth.uiowa.edu]

Ethmoid Sinusitis

This article presents a case of bilateral ethmoid sinusitis with unilateral proptosis as a presenting sign of an unsuspected prostate carcinoma. [ncbi.nlm.nih.gov]

proptosis as an initial manifestation of metastatic prostate carcinoma. ( 7861473 ) Fortson J.K....Moseley D.L. 1994 15 Radiological case of the month. [malacards.org]

1998 13 Cerebral venous thrombosis associated with maxillary and ethmoid sinusitis--a case report. ( 8750066 ) Lee T.G....Roh J.K. 1995 14 Bilateral ethmoid sinusitis with unilateral [malacards.org]

Pulsating Exophthalmos

[…] or bilateral proptosis were the subjects for the study. [ijri.org]

Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). [icd.codes]

Orbital Burkitt's Lymphoma

Symptoms Orbital tumors typically present with early unilateral proptosis of the globe and may adversely affect visual and extraocular muscle function. [skullbaseinstitute.com]

This report describes the case of a 14-year-old boy who presented with rapidly progressive unilateral proptosis which was found to be round cell tumor on histopathology. [ccij-online.org]

However, our case showed the rare unilateral presentation. The clinical presentation (site and age) has some association with the molecular lesion. [ccij-online.org]

Orbital Disease

Orbital metastases may be unilateral/bilateral and usually present with abrupt proptosis associated with a superior orbital mass. Prognosis is very poor. [patient.info]

A 40 year-old male presented after one year of unilateral, progressive, steroid-responsive, orbital inflammatory disease causing proptosis, extraocular muscle (EOM) restriction [ncbi.nlm.nih.gov]

Signs and Symptoms Sudden onset of unilateral proptosis. Eyelid swelling, injection, ecchymosis. Pain and decreased vision are uncommon. [entokey.com]

Orbital Infection

Signs include unilateral ptosis, proptosis, visual loss, internal and external ophthalmoplegia (ie, palsy of the pupillary and extraocular muscles), and CN V1 (forehead) anesthesia [emedicine.medscape.com]

(2) upper respiratory tract or middle ear Is Preseptal cellulitis unilateral? is there proptosis or EOM restriction? can the eye always open? are VA's affected? [brainscape.com]

Clinically, all patients presented with unilateral proptosis, periorbital edema and tenderness, and restriction of ocular motility. [joii-journal.springeropen.com]

Orbital Floor Fracture

Abstract Three patients developed unilateral proptosis 13, 16, and 20 years after repair of blow-out fracture with orbital floor Teflon implants. [ncbi.nlm.nih.gov]

Cavernous Sinus Thrombosis

Various combinations of these symptoms may occur, which generally are unilateral but may be bilateral with neoplastic processes. [emedicine.com]

Early signs like unilateral facial edema, orbital chemosis, edema, and proptosis should raise high index suspicion of cavernous 1. Ogundiya DA, Keith DA, Mirowski J. [degruyter.com]

To report a rare case of unilateral cavernous sinus thrombosis caused by contralateral sphenoid sinusitis. [ncbi.nlm.nih.gov]

Sellar Tumor with Suprasellar Extension

Ewing's sarcoma of the orbit with intracranial extension: A rare cause of unilateral proptosis. J Pediatr Neurosci 2011;6:36-9. [Full text] 3. Weins AL, Hattab EM. [ruralneuropractice.com]

Surgical excision can be only achieved in unilateral tumors with no visual acuity. [pediatricneurosciences.com]

Therefore, contemporary indications for surgery include single nerve involvement causing progressive, disfiguring proptosis, blindness, or both, or exophytic chiasm tumors [pediatricneurosciences.com]

Orbital Cellulitis

proptosis. [ncbi.nlm.nih.gov]

Clinically, all patients presented with unilateral proptosis, periorbital edema and tenderness, and restriction of ocular motility. [joii-journal.springeropen.com]

Pseudotumor/Idiopathic orbital inflammatory disease/ Non-specific orbital inflammatory disease  Presents as proptosis,pain, diplopia, lid swelling and redness  Usually unilateral [slideshare.net]

Graves Disease

Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy, orbital inflammation and pain which may mimic ophthalmic [ncbi.nlm.nih.gov]

proptosis, asymmetric ophthalmopathy, or visual loss, orbital imaging is advised (CT scan or MRI).2,5 In patients with tachyarrhythmias, an electrocardiogram should evaluate [the-hospitalist.org]

[…] large goiters, when there are signs or symptoms of upper airway or thoracic outlet obstruction, imaging with a neck and upper-chest CT scan is recommended.2 In patients with unilateral [the-hospitalist.org]

Suprasellar Tumor

Ewing's sarcoma of the orbit with intracranial extension: A rare cause of unilateral proptosis. J Pediatr Neurosci 2011;6:36-9. [Full text] 3. Weins AL, Hattab EM. [ruralneuropractice.com]

Surgical excision can be only achieved in unilateral tumors with no visual acuity. [ncbi.nlm.nih.gov]

Therefore, contemporary indications for surgery include single nerve involvement causing progressive, disfiguring proptosis, blindness, or both, or exophytic chiasm tumors [ncbi.nlm.nih.gov]

Langerhans-Cell Histiocytosis

Orbital psuedotumor represents the second most common inflammatory disorder of the orbit in childhood and may present with unilateral or bilateral proptosis of explosive onset [eyewiki.aao.org]

[…] antigen presenting function of the dendritic cells would remain unknown for more than a century. [13] Differential diagnosis Orbital cellulitis is the most common cause of proptosis [eyewiki.aao.org]

Granulomatosis with Polyangiitis

Note prominent proptosis. Most orbital pseudotumors are unilateral and either extraconal or transspatial (both extra- and intraconal) in distribution. [doi.org]

Rhinocerebral Mucormycosis

[…] periorbital facial pain, orbital inflammation, eyelid edema, blepharoptosis, proptosis, acute ocular motility changes, internal or external ophthalmoplegia, headache or acute [consultant360.com]

V1 and V2 branches of trigeminal nerve, facial nerve paralysis, proptosis, blindness due to optic nerve involvement, nasal obstruction, nasal discharge and aural fullness [hindawi.com]

As the infection spreads, ptosis, proptosis, loss of extraocular muscle function, and vision disturbance may occur. [cdc.gov]

Non-Hodgkin Lymphoma

You are here Home Types of Cancer Lymphoma - Non-Hodgkin Lymphoma - Non-Hodgkin This is Cancer.Net’s Guide to Lymphoma - Non-Hodgkin. Use the menu below to choose the Introduction section to get started. Or, you can choose another section to learn more about a specific question you have. Each guide is[…] [cancer.net]

Meningioma

Meningioma (Frontal). (Left) T1-weighted with gadolinium parasagittal MRI; (Middle) T1-weighted axial MRI; (Right) T1-weighted with gadolinium axial MRI. Note the large, well demarcated mass that is dural based and compresses the adjacent frontal lobe. The mass is isointense on T1-weighted images but strongly enhances[…] [casemed.case.edu]

Hodgkin Lymphoma

The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a[…] [ncbi.nlm.nih.gov]

Endophthalmitis

Endophthalmitis is a severe inflammation of the interior of the eye caused by the introduction of contaminating micro-organisms following trauma, surgery, or hematogenous spread from a distant infection site. It may be categorized by clinical course (acute versus chronic), by etiology (infectious versus[…] [touchophthalmology.com]

Orbital Varix

The authors report a case of a 74-year-old male with progressively painful unilateral proptosis. [scholarworks.utrgv.edu]

Orbital varix thrombosis: a rare cause of unilateral proptosis Summary Orbital varices are thin walled, low flow, distensible veins which may rarely present with periorbital [casereports.bmj.com]

A patient presented with unilateral proptosis which was compressible and increases on bending forward. No thrill or bruit was present. [pgblazer.com]

Pilocytic Astrocytoma

Juvenile pilocytic astrocytoma, the most common pediatric central nervous system (CNS) neoplasm, characteristically displays an indolent growth pattern and rarely demonstrates metastatic dissemination. Reports of infections mimicking CNS metastatic disease are also rare and can impact treatment. We report the[…] [ncbi.nlm.nih.gov]

Melkersson-Rosenthal Syndrome

IN 1928, Melkersson 1 wrote of a 35-year-old female patient afflicted with facial paralysis and facial edema. In 1931, Rosenthal 2 described two families who displayed three cases of lingua plicata associated with the facial paralyses and facial edema. Prior to these descriptions, Hubschmann, 3 in 1894, and Rossolimo, 4 in[…] [jamanetwork.com]

Cervicofacial Actinomycosis

Cervicofacial actinomycosis in children is a rare disorder. This article reports a case in a 7-year-old-girl. The importance of cervicofacial actinomycosis in the differential diagnosis of cervical masses in young patients is emphasized. [ncbi.nlm.nih.gov]

Infantile Cortical Hyperostosis

Infantile cortical hyperostosis manifesting as congenital unilateral proptosis. [pubfacts.com]

PubMed Google Scholar, Iliff and Ossofsky described the case of an infant presenting with unilateral proptosis at 4 weeks of age. [canadianjournalofophthalmology.ca]

Infantile cortical hyperostosis manifesting as congenital unilateral proptosis. Can J Ophthalmol. 2018 Dec. 53 (6):e249-e252. [QxMD MEDLINE Link]. [Full Text]. [emedicine.medscape.com]

Orbital Pseudotumor

Both unilateral proptosis (2 cases) and radiological evidence of orbital inflammatory pseudotumor in the absence of exophthalmos (1 case) have been separately described as [ncbi.nlm.nih.gov]

We describe two patients with unilateral proptosis, diplopia, palpable orbital masses, ocular discomfort, and sinus problems of short duration. [ncbi.nlm.nih.gov]