Upper Limb Spasticity: Causes & Reasons

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Possible Causes for Upper Limb Spasticity

Autosomal Dominant Spastic Paraplegia Type 8

Other features may include upper limb spasticity, impaired vibration sense in the distal lower limbs, and urinary urgency or incontinence (summary by {1:de Bot et al., 2013 [diseaseinfosearch.org]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

Examination at the age of 67 revealed spastic paraparesis, dysarthria and mild upper limb ataxia. [journals.plos.org]

Autosomal Dominant Spastic Paraplegia Type 29

limbs Not very common - Between 30% and 50% cases Upper limb spasticity Commonly - More than 50% cases Impaired proprioception Not very common - Between 30% and 50% cases [mendelian.co]

[…] paraplegia 0001258 Upper limb spasticity Uncontrollable movement in upper arms 0006986 Urinary hesitancy Difficulty with flow 0000019 Urinary incontinence Loss of bladder [rarediseases.info.nih.gov]

Hand tremor and upper limb spasticity have also been reported. Onset can range from infancy to older adulthood. [flybase.org]

Autosomal Recessive Spastic Paraplegia Type 44

Hand tremor and upper limb spasticity have also been reported. Onset can range from infancy to older adulthood. [flybase.org]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

The pure types involve only the lower limbs, whereas the complex types also involve the upper limbs (to a lesser degree) and the nervous system. [ghr.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 46

limb amyotrophy 0009129 Upper limb muscle weakness Decreased arm strength Weak arm [ more ] 0003484 Upper limb spasticity Uncontrollable movement in upper arms 0006986 Percent [rarediseases.info.nih.gov]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [ghr.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 20

[…] paraplegia 0001258 Upper limb spasticity Uncontrollable movement in upper arms 0006986 Showing of 84 | Last updated: 5/1/2019 Troyer syndrome is caused by mutations in the [rarediseases.info.nih.gov]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [icdlist.com]

Infantile-Onset Ascending Hereditary Spastic Paralysis

is a very rare motor neuron disease characterized by severe spasticity of the lower limbs in early life, progression of spasticity to the upper limbs in late childhood, [amp.pharm.mssm.edu]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

limb spasticity in addition to spastic paraparesis. [ojrd.biomedcentral.com]

Autosomal Dominant Spastic Paraplegia Type 10

limb spasticity Uncontrollable movement in upper arms 0006986 Percent of people who have these symptoms is not available through HPO Autosomal dominant inheritance 0000006 [rarediseases.info.nih.gov]

Orpha Number: 100991 Disease definition A rare type of hereditary spastic paraplegia that can present as either a pure form of spastic paraplegia with lower limb spasticity [rarediseases.info.nih.gov]

limb amyotrophy, moderate intellectual disability and parkinsonism. [rarediseases.info.nih.gov]

Autosomal Dominant Spastic Paraplegia Type 17

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

[…] by progressive spastic paraplegia, upper and lower limb muscle atrophy, hyperreflexia, extensor plantar responses, pes cavus and occasionally impaired vibration sense. [orpha.net]

Focal muscle vibration in the treatment of upper limb spasticity: a pilot randomized controlled trial in patients with chronic stroke. [en.wikipedia.org]

Autosomal Recessive Spastic Paraplegia Type 53

SPG53 is characterized by pronounced early onset spastic paraparesis of upper and lower limbs, mild intellectual disability, kyphosis, pectus carinatum and hypertrichosis. [malacards.org]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

OMIM : 57 SPG53 is an autosomal recessive neurologic disorder characterized by onset in infancy of delayed motor development progressing to upper and lower limb spasticity [malacards.org]

Autosomal Recessive Spastic Paraplegia Type 55

Hand tremor and upper limb spasticity have also been reported. Onset can range from infancy to older adulthood. [flybase.org]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [ghr.nlm.nih.gov]

Autosomal Dominant Spastic Paraplegia Type 37

[…] cases Progressive spasticity Impaired proprioception Lower limb amyotrophy Upper limb spasticity Knee clonus Female sexual dysfunction Male sexual dysfunction Gait disturbance [mendelian.co]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

In SPG56, upper limbs are often also affected. Some SPG56 patients may have a subclinical axonal neuropathy. [malacards.org]

Autosomal Recessive Spastic Paraplegia Type 56

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

In SPG56, upper limbs are often also affected. Some SPG56 patients may have a subclinical axonal neuropathy. [malacards.org]

The pure types involve only the lower limbs, whereas the complex types also involve the upper limbs (to a lesser degree) and the nervous system. [ghr.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 39

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

Examination showed increased reflexes in the lower limbs (LL) and flexor plantar responses. Reflexes were normal in the upper limbs. [academic.oup.com]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [ghr.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 18

[…] paraplegia 0001258 Strabismus Cross-eyed Squint Squint eyes [ more ] 0000486 Upper limb spasticity Uncontrollable movement in upper arms 0006986 Showing of 42 | Last updated [rarediseases.info.nih.gov]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [ghr.nlm.nih.gov]

X-Linked Spastic Paraplegia Type 34

Hand tremor and upper limb spasticity have also been reported. Onset can range from infancy to older adulthood. [flybase.org]

Spasticity of the upper limb in adults. [aetna.com]

Examination at the age of 67 revealed spastic paraparesis, dysarthria and mild upper limb ataxia. [journals.plos.org]

Autosomal Dominant Spastic Paraplegia Type 13

60 33 occasional (7.5%) Occasional (29-5%) HP:0008075 14 ankle clonus 33 occasional (7.5%) HP:0011448 15 upper limb spasticity 33 occasional (7.5%) HP:0006986 16 muscle spasm [malacards.org]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [ghr.nlm.nih.gov]

Cerebral Palsy with Spastic Diplegia

limbs) G83.0 ICD-10-CM Diagnosis Code G83.0 Diplegia of upper limbs 2016 2017 2018 2019 Billable/Specific Code Applicable To Diplegia (upper) Paralysis of both upper limbs [icd10data.com]

Effect on the upper limbs (arms and hands) If spasticity affects one or both of the arms it can lead to: Flexion at the elbow (the elbow is bent) Flexion at the wrist (the [cerebralpalsy.org.au]

In Spastic diplegia the lower limbs are affected with little to no upper-body spasticity. The most common form of the spastic forms is spastic diplegia. [news-medical.net]

Autosomal Dominant Spastic Paraplegia Type 42

Hand tremor and upper limb spasticity have also been reported. Onset can range from infancy to older adulthood. [flybase.org]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

limb spasticity in addition to spastic paraparesis. [ojrd.biomedcentral.com]

Autosomal Recessive Spastic Paraplegia Type 63

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [ghr.nlm.nih.gov]

[…] paraplegia was earlier and they had additional clinical features including sphincter disturbances, dysarthria, mild cerebellar ataxia of the upper limbs, and further intellectual [jnnp.bmj.com]

Autosomal Recessive Spastic Paraplegia Type 64

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

Examination at the age of 67 revealed spastic paraparesis, dysarthria and mild upper limb ataxia. [journals.plos.org]

There are occasional reports of mild distal muscle atrophy but more marked involvement of the upper limbs with spasticity, weakness, or amyotrophy is not usually seen in pure [jnnp.bmj.com]

Autosomal Dominant Spastic Paraplegia Type 41

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

In SPG56, upper limbs are often also affected. Some SPG56 patients may have a subclinical axonal neuropathy. [malacards.org]

Examination at the age of 67 revealed spastic paraparesis, dysarthria and mild upper limb ataxia. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 26

Some patients have upper limb involvement. [malacards.org]

The progression of the disease has been slow; at age 54, there were marked weakness in the lower limbs and moderate ataxia in the upper limbs. [docplayer.net]

[…] paraplegia characterized by onset in the first 2 decades of life of gait abnormalities due to lower limb spasticity and muscle weakness. [malacards.org]

Spastic Paraparesis-Deafness Syndrome

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [icdlist.com]

Examination at the age of 67 revealed spastic paraparesis, dysarthria and mild upper limb ataxia. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 24

Hand tremor and upper limb spasticity have also been reported. Onset can range from infancy to older adulthood. [flybase.org]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

Examination showed increased reflexes in the lower limbs (LL) and flexor plantar responses. Reflexes were normal in the upper limbs. [academic.oup.com]

Autosomal Recessive Spastic Paraplegia Type 14

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

Examination showed increased reflexes in the lower limbs (LL) and flexor plantar responses. Reflexes were normal in the upper limbs. [academic.oup.com]

The complex types involve the lower limbs and can affect the upper limbs to a lesser degree. [icdlist.com]

Autosomal Recessive Spastic Paraplegia Type 49

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

Examination showed increased reflexes in the lower limbs (LL) and flexor plantar responses. Reflexes were normal in the upper limbs. [academic.oup.com]

She first noticed gait disturbance and spasticity in the lower extremities together with nocturnal leg cramps and pain attacks in the upper limbs at age of 28 years. [omicsonline.org]

Autosomal Recessive Spastic Paraplegia Type 48

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

She first noticed gait disturbance and spasticity in the lower extremities together with nocturnal leg cramps and pain attacks in the upper limbs at age of 28 years. [omicsonline.org]

Examination at the age of 67 revealed spastic paraparesis, dysarthria and mild upper limb ataxia. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 23

[…] presenting with lower limb (followed by upper limb) spasticity with hyperreflexia and extensor plantar responses, with additional manifestations including progressive dysarthria [monarchinitiative.org]

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

She first noticed gait disturbance and spasticity in the lower extremities together with nocturnal leg cramps and pain attacks in the upper limbs at age of 28 years. [omicsonline.org]

Pure Hereditary Spastic Paraplegia

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

CONCLUSIONS: Axonal integrity of projections to the upper limbs is unimpaired in patients with pure HSP. [ncbi.nlm.nih.gov]

The pure types involve only the lower limbs, whereas the complex types also involve the upper limbs (to a lesser degree) and the nervous system. [ghr.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 27

Focalized 100 Hz vibration improves function and reduces upper limb spasticity: a double-blind controlled study. [en.wikipedia.org]

Examination at the age of 67 revealed spastic paraparesis, dysarthria and mild upper limb ataxia. [journals.plos.org]

The latter comprises, in addition to spastic paraplegia, cerebellar symptoms, amyotrophy of the upper limbs, extrapyramidal signs, ophthalmoplegia, optic neuropathy, retinal [ajnr.org]