Create issue ticket

356 Possible Causes for Upslanting Palpebral Fissures

  • Kaufman Oculocerebrofacial Syndrome

    palpebral fissures, depressed nasal bridge. and anteverted nares.[] palpebral fissures, eye abnormalities (microcornea, strabismus, myopia, optic atrophy), high-arched palate, preauricular skin tags and micrognathia with respiratory distress[] palpebral fissures / mongoloid slanting palpebral fissures Frequent - Absent / decreased / thin eyebrows - Blepharophimosis / short palpebral fissures - Complete / partial[]

  • Wolcott-Rallison Syndrome

    Libyan J Med. 2013 Jan;8(1):21137. doi: 10.3402/ljm.v8i0.21137. Author information 1 a Endocrine and Diabetes Unit , Maternity and Children Hospital , Al-Madinah , Saudi Arabia. Abstract Background Wolcott-Rallison syndrome (WRS) is caused by recessive EIF2AK3 gene mutations and characterized by permanent neonatal[…][]

  • Down Syndrome

    Typical facies with upslanting palpebral fissures is the characteristic feature of this syndrome (hence the offensive designations "mongoloid idiocy" and "mongolism").[] Morphological features (upslanting palpebral fissures, epicanthus, flat neck, round face, small nose, bilateral single palmar crease) can be mild and do not constitute a hallmark[] In addition to ocular features related to DS such as epicanthal folds, narrowed or slanted palpebral fissures (the mongoloid slant) and Brushfield spots (38–85%)(Fig. 4 ),[]

  • Renpenning Syndrome 1

    The craniofacies tends to be narrow and tall with upslanting palpebral fissures, abnormal nasal configuration, cupped ears, and short philtrum.[] Characteristic craniofacial features include long triangular faces with upslanting palpebral fissures, half-depilated eyebrows, large ridged or bulbous nose with overhanging[] Facial features characteristic of this disorder include a long, narrow face; outside corners of the eyes that point upward (upslanting palpebral fissures); a long, bulbous[]

  • Zellweger Syndrome

    palpebral fissures, epicanthal folds, and broad nasal bridge), profound hypotonia and seizures.[] Infants with Zellweger syndrome present with flattened facies, large anterior fontanel, split sutures, a prominent high forehead, a flattened occiput, upslanting palpebral[] Typical Facies epicanthal folds high forehead hypoplastic supraorital ridges upslanting palpebral fissures 2.[]

  • Blepharofacioskeletal Syndrome

    Upslanted palpebral fissure MedGen UID: 98390 • Concept ID: C0423109 • Finding The palpebral fissure inclination is more than two standard deviations above the mean for age[] Other anomalies are blepharophimosis, upslant of palpebral fissures, and a tendency to cutaneous syndactyly of 3rd and 4th fingers as well as 2nd and 3rd toes.[]

  • Miller Dieker Syndrome

    palpebral fissures, protuberant upper lip, thin vermilion border of upper lip, and micrognathia (Figure 47.1 [B]).[] Dysmorphic features may include everted lips, deep-set eyes, upslanting palpebral fissures, hypertelorism, synophris, prominent philtrum and hypotonic facies.[] […] facial features: microcephaly with bitemporal narrowing, vertical ridging and furrowing in the central forehead (especially when crying), small nose with antiverted nostrils, upslanting[]

  • Spondyloepiphyseal Dysplasia, Cantu Type

    palpebral fissures curly eyebrows Skeletal: small epiphyses spondyloepiphyseal dysplasia mild joint contractures generalized epiphyseal ossification delay Respiratory Lung[] […] brachydactyly short hands small carpals short, tapered phalanges single interphalangeal crease of fifth finger more Head And Neck Eyes: blepharophimosis curly eyelashes upslanting[]

  • Pallister-Killian Syndrome

    palpebral fissures, hypertelorism, flat and broad nasal bridge, short nose with upturned nares, large mouth with downturned corners and prominent upper lip.[] Craniofacial manifestations include a coarse'' face with flat profile, high forehead with temporo-frontal balding, sparseness of eyebrows and lashes, shallow supraorbital ridges, upslanting[]

  • Trigonocephaly

    The girl was the first-born child of consanguineous parents and had trigonocephaly, apparent hypertelorism, upslanted palpebral fissures, strabismus, small nose with broad[] The proband was initially diagnosed with Opitz trigonocephaly syndrome on the basis of metopic craniosynostosis, upslanting palpebral fissures, high arched palate, redundant[] Both children showed the pattern of abnormal findings characteristic of this syndrome, including trigonocephaly, upslanted palpebral fissures, inner epicanthic folds, broad[]

Further symptoms

Similar symptoms