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74 Possible Causes for Uric Acid Increased, Vitamin B12 Increased

  • Polycythemia Vera

    Polycythemia Vera Laboratory findings Elevated Hct – often 60% Increased WBCs and platelets Serum EPO levels are low Decreased iron stores (Ferritin) Increased Vitamin B12[] B12 level Plethora, a ruddy complexion of face, palms, nail beds, mucosa, and conjunctiva, due to the increased total red blood cell count.[] […] there and uric acid is just a metabolyte of deoxyribonucleic acid, or DNA, and so increased DNA breakdown will result in increased uric acid being built up in the body.[]

  • Acute Myelocytic Leukemia

    Vitamin B12 deficiency May have a family history consistent with pernicious anemia. Paresthesia is an early symptom.[] Hyperleukocytosis also increases the odds of spontaneous TLS and the number of blasts contributing to the uric acid load.[] acid; in late stages, leukocytes infiltrate the kidneys - Enlarged organs (spleen,liver)- Caused by increased number of white blood cells accumulating within liver and spleen[]

  • Chronic Phase of Chronic Myeloid Leukemia

    acid – gout/uropathy Histamine increase with basophil 90% In normal cells, two red and two green signals indicate the location of the normal ABL and BCR genes, respectively[] […] turnover of glucocerebrocide* Collagen type III – correlates with spleen size and megakaryocytosis* Angiogenetic marrow – reduces with treatment B12 – immature cell leak Uric[] […] face *Massive - and in almost all patients Sternal tenderness – lower part – patient can detect Neutrophil alkaline phosphatase activity is low or absent (90%) - Activity increases[]

  • Acute Erythroblastic Leukemia

    B12 and folate deficiency.[] Features associated with pernicious anemia are hemolysis with increased mean corpuscular volume (MCV), hypersegmented neutrophils, leukopenia and thrombocytopenia increased[] […] erythroid lineage with no evidence of a significant myeloid component The most common reactive process that can mimic acute erythroid leukemia is megaloblastic anemia caused by vitamin[]

  • Non-Hodgkin Lymphoma

    acid.[] acid and LDH are at increased risk of tumor lysis syndrome resulting in metabolic derangements such as hyperuricemia, hyperkalemia, hyperphosphatemia, hypocalcemia, and subsequent[] […] better predict survival after standard chemotherapy.[ 33 , 34 ] Treatment of tumor lysis syndrome Patients with bulky and extensive lymphadenopathy and elevations of serum uric[]

  • Acute Monocytic Leukemia

    Hyperleukocytosis also increases the odds of spontaneous TLS and the number of blasts contributing to the uric acid load.[] TLS consists of a combination of high potassium and phosphate with low calcium as well as high uric acid and increased creatinine.[]

  • Myeloproliferative Disease

    -Total protein, BUN, creatinine, uric acid elevated -Hypercalcemia in 1/3 of patients -40% Bence Jones proteinuria * need sulfosalicylic acid urine test to detect.[] -Serum protein electrophoresis SPELP: * increased monoclonal Ig protein, or "M protein" in 80% Plasma Cell Dyscrasias (PCDs) -Waldenstrom's Macroglobulinemia * Definition[]

  • Pernicious Anemia

    However, his vitamin B12 levels were increased due to vitamin B12 supplementation therapy, which was initiated earlier.[] Shots usually are given in a muscle every day or every week until the level of vitamin B12 in your blood increases.[] Dietary deficiency of vitamin B12 due to vegetarianism is increasing and causes hyperhomocysteinemia.[]

  • Chronic Alcoholism

    Folic acid and vitamins B6 and B12 deficiency may lead to hyperhomocysteinemia, as they participate in its metabolism.[] Gout Gout is a type of arthritis caused by the formation of uric acid crystals in the joints. It can be very painful.[] DISCUSSION: An increase in homocysteine levels is common in alcoholics, and it has been considered a vascular risk factor.[]

  • Diabetes Mellitus

    False elevations of HbA1C may occur with low RBC turnover (as occurs with iron, folate, or vitamin B12 deficiency anemia), high-dose aspirin , and high blood alcohol concentrations[] […] lowering uric acid levels prevented the increase in mean arterial blood pressure ( 40 ).[] […] whereas uric acid (HR per 1 mmol/L increase, 2.05) and physical inactivity during leisure time (HR, 1.80) were associated with diabetes development in women only.[]

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