Namely, mutations of FGF23, regardless of the underlying cause, lead to reduced activity of NaPi2a and NaPi2c, causing increased phosphate wasting through urine as they are
[symptoma.com]
Phosphate levels in the blood are low as phosphate is abnormally processed in kidneys, which causes a loss of phosphate in urine and leads to soft and weak bones.
[medgadget.com]
The growing prevalence of X-linked hypophosphatemia, increasing healthcare expenditure, and rising prevalence of genetic diseases are anticipated to drive the growth of the
[medgadget.com]
Acromegaly is characterized by excessive secretion of growth hormone, usually caused by a somatotroph pituitary adenoma. The diagnosis of acromegaly is frequently delayed due to the slow progression of signs and symptoms. Patients with large tumors may experience symptoms due to the local mass effects of the[…]
[symptoma.com]
[Article in French] Affiliations PMID: 33058640 [Schimmelpenning-Feuerstein-Mims syndrome] [Article in French] Sabah Bazouti et al. Rev Prat. 2020 May. No abstract available Keywords: Jadassohn's Sebaceous Nevus. Conflict of interest statement Les auteurs déclarent n’avoir aucun lien d’intérêts. Similar articles[…]
[pubmed.ncbi.nlm.nih.gov]
(hypophosphatemia) Increased urine phosphate (phosphaturia) Glucose in the urine (glycosuria) Excess serum protein in urine (proteinuria) Excess uric acid in the urea (hyperuricosuria
[news-medical.net]
Signs and symptoms of Fanconi Syndrome are: Dehydration due to increased urination; increased thirst Presence of glucose, phosphates, and protein, in urine Adults suffer from
[dovemed.com]
[…] hypokalemia) High blood chloride (hyperchloremia) Symptoms of the generalized proximal renal tubule dysfunction seen in Fanconi syndrome include the following: Low blood phosphate
[news-medical.net]
(hypophosphatemia) Increased urine phosphate (phosphaturia) Glucose in the urine (glycosuria) Excess serum protein in urine (proteinuria) Excess uric acid in the urea (hyperuricosuria
[news-medical.net]
[…] hypokalemia) High blood chloride (hyperchloremia) Symptoms of the generalized proximal renal tubule dysfunction seen in Fanconi syndrome include the following: Low blood phosphate
[news-medical.net]
Considerably increased renal elimination of phosphates in diabetics manifested by elevated values of the phosphate clearance. — 2.
[link.springer.com]
[…] levels in the serum and urine of 106 diabetic patients and 25 controls, the following has been established: 1.
[link.springer.com]
[…] mellitus und einigen seiner Komplikationen Diabetologia volume 2, pages 198–201 (1966)Cite this article 136 Accesses 7 Citations Metrics details Summary From a study of the phosphate
[link.springer.com]
(hypophosphatemia) Increased urine phosphate (phosphaturia) Glucose in the urine (glycosuria) Excess serum protein in urine (proteinuria) Excess uric acid in the urea (hyperuricosuria
[news-medical.net]
A 24-hour urine collection revealed increased Phosphate, and Potassium levels ( Table 1 ).
[ncbi.nlm.nih.gov]
[…] hypokalemia) High blood chloride (hyperchloremia) Symptoms of the generalized proximal renal tubule dysfunction seen in Fanconi syndrome include the following: Low blood phosphate
[news-medical.net]
[…] of calcium plus increased pH levels in your urine (calcium phosphate).
[mykidneystone.com]
The most important risk factor for uric acid crystallization and stone formation is a low urine pH (below 5.5) rather than an increased urinary uric acid excretion.
[ncbi.nlm.nih.gov]
The major causes include those associated with an increase in urinary levels of calcium, oxalate and phosphate.
[ncbi.nlm.nih.gov]
Under these conditions, urine concentration and supersaturation leads to calcium crystal precipitation, which may be an intratubular event or initiate within the renal interstitium
[ncbi.nlm.nih.gov]
(hypophosphatemia) Increased urine phosphate (phosphaturia) Glucose in the urine (glycosuria) Excess serum protein in urine (proteinuria) Excess uric acid in the urea (hyperuricosuria
[news-medical.net]
[…] hypokalemia) High blood chloride (hyperchloremia) Symptoms of the generalized proximal renal tubule dysfunction seen in Fanconi syndrome include the following: Low blood phosphate
[news-medical.net]
Other Laboratory Findings Increased urine phosphate due to decreased renal tubular reabsorption Increased urine calcium due to increased intestinal absorption, increased renal
[hoslink.com]
Increased secretion of hydroxyproline and phosphate in urine is possible.
[lecturio.com]
[…] tubular reabsorption, and increased mobilisation from bone Increased urine volume due to increased urinary phosphate and calcium Decreased and fixed urine specific gravity
[hoslink.com]
Evaluation: Normal Renal Function Check Urinary phosphate excretion (Urine pHosphate) Increased Urine pHosphate: over 1500 mg/dl Endogenous source Cytotoxins Rhabdomyolysis
[fpnotebook.com]
Evaluation: Normal Renal Function Check Urinary phosphate excretion ( Urine pH osphate) Increased Urine pH osphate: over 1500 mg/dl Endogenous source Cytotoxins Rhabdomyolysis
[fpnotebook.com]
PTH works by increasing calcium reabsorption from the urine back into circulation by the kidneys. PTH also causes decreased reabsorption of phosphate at the kidneys.
[prognosisquestions.com]
(hypophosphatemia) Increased urine phosphate (phosphaturia) Glucose in the urine (glycosuria) Excess serum protein in urine (proteinuria) Excess uric acid in the urea (hyperuricosuria
[news-medical.net]
urine is then acidified by the intercalated cells in collecting tubule Diagnostic criteria no specific criteria but these findings could suggest Fanconi syndrome increased
[step2.medbullets.com]
urine is then acidified by the intercalated cells in collecting tubule Diagnostic criteria no specific criteria, but these findings could suggest Fanconi syndrome increased
[medbullets.com]
Twenty four hour urine demonstrated a low renal fractional tubular reabsorption of phosphate, increased fractional excretion of uric acid and generalized aminoaciduria.
[keio.pure.elsevier.com]
urine is then acidified by the intercalated cells in collecting tubule Diagnostic criteria no specific criteria but these findings could suggest Fanconi syndrome increased
[medbullets.com]
Symptoms: Excess amounts of the following substances in the urine: amino acids, glucose, phosphate, magnesium, potassium, bicarbonate and sodium.
[sinoemedicalassociation.org]
Dietary phosphate restriction, if severe, increases urine calcium excretion.
[emedicine.com]
Significant increases in urine citrate (MD = 0.85 mmol, 95% CI: 0.01-1.68, P = 0.046), magnesium (MD = 0.69 mmol, 95% CI: 0.13-1.25, P = 0.016) and phosphate (MD = 2.28 mmol
[ncbi.nlm.nih.gov]
In general, urinary calcium increases with dietary calcium intake (see Hypercalciuria ). Urinary calcium increases in patients with high sodium chloride intake.
[emedicine.com]
Struvite stone formation can be sustained only when ammonia production is increased and the urine pH is elevated to decrease the solubility of phosphate.
[emedicine.medscape.com]
Struvite stones are composed of a combination of magnesium ammonium phosphate (struvite) and calcium carbonate-apatite.
[emedicine.medscape.com]
The major causes include those associated with an increase in urinary levels of calcium, oxalate and phosphate.
[ncbi.nlm.nih.gov]
Under these conditions, urine concentration and supersaturation leads to calcium crystal precipitation, which may be an intratubular event or initiate within the renal interstitium
[ncbi.nlm.nih.gov]
[…] in FGF-23 General features of renal phosphate wasting, normal serum calcium, low/normal urine calcium, and high alkaline phosphatase Rickets/osteomalacia, short stature,
[merckmanuals.com]
Albright observed that the correction of hypocalcemia increased urine phosphate excretion.
[revistanefrologia.com]
[…] phosphatonin (FGF-23) production Renal phosphate wasting with normal serum calcium, normal or low urine calcium, high alkaline phosphatase, normal or paradoxically high intact
[merckmanuals.com]
By increasing intravascular volume and urine output, it increases the renal excretion of uric acid and phosphate.
[healio.com]
Urine alkalinization is somewhat controversial. If urine is too alkaline, calcium phosphate crystal formation may occur, increasing the likelihood of renal failure.
[encyclopedia.com]
This causes an increased serum concentration of calcium, phosphate, magnesium, urine substances, and uric acid.
[oncolex.org]
This infant demonstrated an increased urine excretion of glycerol-3-phosphate during episodes of hypoglycaemia.
[ncbi.nlm.nih.gov]
Urinary organic acid analysis during crises revealed markedly increased excretion of lactate, ketone bodies, glycerol and glycerol-3-phosphate.
[ncbi.nlm.nih.gov]
We newly identified other glycolytic intermediates, glyceraldehyde, 3-phosphoglycerate and fructose-1,6-diphosphate, in the urine during hypoglycaemic attacks or after fructose
[ncbi.nlm.nih.gov]
(hypophosphatemia) Increased urine phosphate (phosphaturia) Glucose in the urine (glycosuria) Excess serum protein in urine (proteinuria) Excess uric acid in the urea (hyperuricosuria
[news-medical.net]
Calcium and phosphate release from bone causes hypercalciuria. Secondly, persistent alkaline urine promotes calcium phosphate stone formation.
[clinicaladvisor.com]
There may be increased or normal excretion of calcium, citrate, or phosphate in urine, while there may be decreased or normal excretion of NH 4 + in the urine.
[lecturio.com]
Development of the stones is related to decreased urine volume or increased excretion of stone-forming components such as calcium, oxalate, urate, cystine, xanthine, and phosphate
[medicinenet.com]
These organisms produce urea-splitting enzymes, resulting in increased concentration of ammonia and bicarbonate in the urine, thereby predisposing patients to an increased
[radiologykey.com]
Acidic urine (low pH) predisposes to the formation of uric acid and cystine stones, whereas alkaline urine (high pH) favors calcium phosphate stones.
[mdedge.com]
Development of the stones is related to decreased urine volume or increased excretion of stone-forming components such as calcium, oxalate, urate, cystine, xanthine, and phosphate
[medicinenet.com]
Diagnostic methods Diagnosis is usually based on clinical features, plasma and urine electrolytes showing hypophosphatemia, hyperphosphaturia, hypercalciuria and increased
[orpha.net]
Urine (24 hours): creatinine, uric acid, calcium, phosphate, oxalate or cystine increases. 3.
[duniamayadokter.blogspot.com]
Dietary factors, high doses of vitamin D, intestinal bypass surgery and several metabolic disorders can increase the concentration of calcium or oxalate in urine.
[mayoclinic.org]
[…] glycerol 3 phosphate increase, and a deletion, not previously described, in the glycerol kinase gene.
[scielo.isciii.es]
He was diagnosed of hyperglycerolemia due to glycerol kinase deficiency (GKD) based on: transparent non-lipemic serum, with glycerol increase in plasma and urine, without
[scielo.isciii.es]
[…] calcium excretion in urine Nephrocalcinosis, or increased calcium in the kidneys Hyperphosphatemia (elevated phosphate levels in blood) Hypermagnesuria (increased magnesium
[dovemed.com]
[…] calcium in blood [ more ] 0003072 Hypermagnesemia High blood magnesium levels 0002918 Hypocalciuria Low urine calcium levels 0003127 Hypophosphatemia Low blood phosphate
[rarediseases.info.nih.gov]
[…] in urine) Hypomagnesemia (low levels of magnesium in blood) Kidney stones Kidney malfunction Many individuals with Autosomal Dominant Hypocalcemia may remain asymptomatic
[dovemed.com]
Urine sample T he most important measure of excessive cadmium exposure is increased cadmium excretion in the urine, and this finding reflects the concentration.
[pathopedia-india.com]
The effects of cadmium proximal renal function are characterized by increased cadmium in the urine, proteinuria (primarily Beta-2-microglobulin), aminoaciduria, glycosuria
[pathopedia-india.com]
and decreased renal tubular reabsorption of phosphate.
[pathopedia-india.com]
PTH also increases urinary excretion of phosphate.
[usmleforum.com]
[…] the urine (hypercalciuria).
[usmleforum.com]
The excess calcium in the urine predisposes to renal stone formation, especially calcium oxalate or calcium phosphate stones.
[usmleforum.com]
Phosphate urine, Creatinine urine, with calculation of fractional excretion of phosphate.
[rcpa.edu.au]
This is turn causes an increase in renal excretion of phosphate and reduced loss of calcium in the urine.
[pathology.leedsth.nhs.uk]
[…] and phosphate.
[n.neurology.org]
It leads to urine alkalinity and increased ammonia concentration. Accompanied with phosphate and magnesium in the urine, these enable crystallization of struvite stones.
[kidneystonespassed.com]
Urease hydrolyzes (or splits) urea into ammonium and hydroxyl ions resulting in an increase in ammonium and phosphate concentrations leading to an alkaline urine.
[sharecare.com]
These organisms produce urea-splitting enzymes, resulting in increased concentration of ammonia and bicarbonate in the urine, thereby predisposing patients to an increased
[radiologykey.com]