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6 Possible Causes for Urine Succinic Acid Increased

  • Tyrosinemia Type 1

    Subsequent urine organic acid analysis showed increased urinary excretion of 4-hydroxyphenyllactate, 4-hydroxyphenylpyruvate, succinate, and succinylacetone.[ncbi.nlm.nih.gov] The patient's newborn screening test revealed increased concentrations of methionine and tyrosine.[ncbi.nlm.nih.gov]

  • Tyrosinemia

    Subsequent urine organic acid analysis showed increased urinary excretion of 4-hydroxyphenyllactate, 4-hydroxyphenylpyruvate, succinate, and succinylacetone.[ncbi.nlm.nih.gov] The patient's newborn screening test revealed increased concentrations of methionine and tyrosine.[ncbi.nlm.nih.gov]

  • Ketoadipicaciduria

    […] may be converted into succinic acid (PMID: 3980660) Specimen Normal Abnormal Severity Associated with diseases urine 0.00-2.00 mmol/mol creatinine 50.00-220.00 mmol/mol creatinine[metagene.de] 2-KETOADIPIC ACIDEMIA urine - 0.00-0.00 increased 2-AMINOADIPIC ACIDURIA (AMOCAD) Associated Dissorders based on hmdb Please note: the following summary based on Human Metabolic[metagene.de] […] consists of at least 95% of the L-enantiomer This finding supports the hypothesis that dicarboxylic acids are degraded by ordinary beta-oxidation, and indicates that adipic acid[metagene.de]

  • Deficiency of Sulfite Oxidase

    […] samples as reflected by increased levels of compounds such as succinic acid, benzoic acid, 2-hydroxyglutaric acid, and uracil [ Sass et al 2010 ].[ncbi.nlm.nih.gov] […] mucolite drug 2-mercaptoethane sulfonate; Certain antibiotics such as cefotaxime, cefuroxime, ampicillin, and benzylpenicillin [ Tan et al 2005 ]; and Bacterial degradation of urine[ncbi.nlm.nih.gov]

  • Hawkinsinuria

    The drug valproic acid may lead to increased excretion of 3-hydroxyisovalerate, 5-hydroxyhexanoate, 7-hydroxyoctanoate, p -hydroxyphenylpyruvate, dicarboxylic acids, and to[clinchem.aaccjnls.org] Of possible exogenous origin (bacterial growth in urine) are d -lactate, 2-ketoglutarate, d -2-hydroxyglutarate, succinate, 3-hydroxypropionate, and phenol derivatives (phenol[clinchem.aaccjnls.org]

  • Pyroglutamate Hydrolase Deficiency

    The drug valproic acid may lead to increased excretion of 3-hydroxyisovalerate, 5-hydroxyhexanoate, 7-hydroxyoctanoate, p -hydroxyphenylpyruvate, dicarboxylic acids, and to[clinchem.aaccjnls.org] The drug valproic acid may lead to increased excretion of 3-hydroxyisovalerate, 5-hydroxyhexanoate, 7-hydroxyoctanoate, p-hydroxyphenylpyruvate, dicarboxylic acids, and to[thefreelibrary.com] Of possible exogenous origin (bacterial growth in urine) are d -lactate, 2-ketoglutarate, d -2-hydroxyglutarate, succinate, 3-hydroxypropionate, and phenol derivatives (phenol[clinchem.aaccjnls.org]

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