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5 Possible Causes for Urine Turns Dark on Standing and Alkalinization

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  • Alkaptonuria

    dark if it is allowed to stand or is alkalinized (a result of formation of polymerization products of homogentisic acid); frequently occurs throughout relatively long periods[medical-dictionary.thefreedictionary.com] 1,2-dioxygenase, which mediates an essential step in the catabolism of phenylalanine and tyrosine; urine turns dark if it is allowed to stand or is alkalinized (a result[medical-dictionary.thefreedictionary.com] Characteristically, the excess homogentisic acid means the patient passes dark urine , which on standing turns black . This is a feature present from birth.[pathopedia-india.com]

  • Ochronosis with Alkaptonuria

    1,2-dioxygenase, which mediates an essential step in the catabolism of phenylalanine and tyrosine; urine turns dark if it is allowed to stand or is alkalinized (a result[medical-dictionary.thefreedictionary.com] Characteristically, the excess homogentisic acid means the patient passes dark urine , which on standing turns black . This is a feature present from birth.[pathopedia-india.com] […] al·cap·ton·u·ri·a , alkaptonuria ( al-kap-ton-yū'rē-ă ), [MIM*203500] Excretion of homogentisic acid (alkapton) in the urine resulting from congenital lack of the enzyme homogentisate[medical-dictionary.thefreedictionary.com]

  • Chronic Progressive External Ophthalmoplegia

    Heart valves calcification Kidneys nephrolithiasis Diagnostics : Urine initially appears normal but turns dark brown or black when left standing or alkalinized .[amboss.com] Confirmed with measurement of homogentisic acid in the urine Homocystinuria Definition : : a group of diseases in which the blood and urine levels of the amino acid homocysteine[amboss.com]

  • Lung Biopsy showing Centrilobular Emphysema

    Heart valves calcification Kidneys nephrolithiasis Diagnostics : Urine initially appears normal but turns dark brown or black when left standing or alkalinized .[amboss.com] Confirmed with measurement of homogentisic acid in the urine Homocystinuria Definition : : a group of diseases in which the blood and urine levels of the amino acid homocysteine[amboss.com]

  • Juvenile Cystinosis

    Heart valves calcification Kidneys nephrolithiasis Diagnostics : Urine initially appears normal but turns dark brown or black when left standing or alkalinized .[amboss.com] Confirmed with measurement of homogentisic acid in the urine Homocystinuria Definition : : a group of diseases in which the blood and urine levels of the amino acid homocysteine[amboss.com]

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