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191 Possible Causes for Vacuolar Degeneration

  • Insect Bite

    The lichenoid reaction is often accompanied by vacuolar degeneration of the basal keratinocytes and the presence of apoptotic bodies (colloid or Civatte bodies).[doi.org]

  • Vitamin B12 Deficiency

    Secondary axonal degeneration occurs as the disease advances leading to fixed neurological deficits.[ispub.com] The myelopathy of vitamin B-12 deficiency is virtually indistinguishable from the vacuolar myelopathy of AIDS.[ispub.com]

  • Actinic Lichen Planus

    The prominent histopathologic features consisted of an interface dermatitis characterized by coarse vacuolar degeneration of the basal cell layer, a mid-dermal perivascular[ncbi.nlm.nih.gov] Histologic findings reveal an interface dermatitis, mostly in the form of mild vacuolar degeneration of the basal layer, perivascular lymphocytic infiltration of the mid-dermis[slideshare.net] Histologically, the epidermis is atrophic along with vacuolar degeneration of basal cell layer.[e-ijd.org]

  • Familial Visceral Myopathy

    The characteristic pathological abnormality was vacuolar degeneration predominantly affecting the longitudinal muscle.[ncbi.nlm.nih.gov] […] of Cajal in small and large bowel ( Am J Surg Pathol 2003;27:228 ) Treatment Diet, octreotide, surgery, transplant Microscopic (histologic) description Visceral myopathy: vacuolar[pathologyoutlines.com] The atrophy is variable but described as a marked vacuolar degeneration of myocytes, loss of muscle fibers, and with or without a highly characteristic honeycomb fibrosis.[ghrnet.org]

  • Chronic Alcoholism

    Muscle biopsy showed atrophic, necrotic, and regenerating fibers, endomysial macrophages, and vacuolar degeneration, interpreted as hypokalemic myopathy.[ncbi.nlm.nih.gov]

  • Ichthyosis Vulgaris

    degeneration of suprabasal keratinocytes and coarse keratohyalin granules in thickened granular layer in keratinopathic ichthyosis What problems does ichthyosis cause?[dermnetnz.org] Biopsy reveals: Thick, hyperkeratotic stratum corneum Reduced or absent granular cell layer and filaggrin in ichthyosis vulgaris Lamellar body ‘ghosts’ in lamellar ichthyosis Vacuolar[dermnetnz.org]

  • Intestinal Pseudo-Obstruction

    […] of Cajal in small and large bowel ( Am J Surg Pathol 2003;27:228 ) Treatment Diet, octreotide, surgery, transplant Microscopic (histologic) description Visceral myopathy: vacuolar[pathologyoutlines.com] degeneration and a degree of secondary subvillous atrophy.[gut.bmj.com] degeneration with swelling and loss of muscle cells, fibrosis of outer longitudinal muscle layer; other cases show cytoplasmic vacuoles, marked nuclear enlargement and irregularity[pathologyoutlines.com]

  • Rare Cutaneous Lichen Planus

    Basal cell vacuolar degeneration was also seen (H and E, 40) Click here to view Vulvovaginal involvement is seen in approximately 57% of women with oral lichen planus while[ijdvl.com] degeneration of the basal cell layer and scarce dermal perivascular or lichenoid infiltrate.[pigmentinternational.com] degeneration of the basal cell layer.[ijpmonline.org]

  • Sick Sinus Syndrome

    Light microscopic analysis of right ventricular endomyocardial biopsies showed vacuolar degeneration and nuclear deformity of cardiomyocytes in all cases and endocardial and[ncbi.nlm.nih.gov]

  • Pityriasis Circinata

    degeneration.[karger.com] Differently from CPR, histopathology reveals necrotic keratinocytes within the epidermis, dermal eosinophil infiltrate, perivascular infiltrate, and signs of junctional vacuolar[karger.com]

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