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283 Possible Causes for Vacuolated Macrophages

  • Common Cold

    […] mechanism for the inverse association between serum 25(OH)D level and URTI. 14 The only known human cathelicidin, hCAP-18 (LL-37), enhances microbial killing in phagocytic vacuoles[dx.doi.org] […] acts as a chemoattractant for neutrophils and monocytes, and has a defined vitamin D–dependent mechanism. 39, 40 Pathogenic antigens interact with toll-like receptors on macrophages[dx.doi.org]

  • Vitamin B12 Deficiency

    Abundant macrophage activity leads to breakdown of the myelin sheaths.[ispub.com] The swollen individual myelinated fibers give a vacuolated sieve-like appearance to stained cross-sections of the spinal cord.[ispub.com]

  • Anemia

    […] by macrophage infiltration.[web.archive.org] As demyelination and vacuolation increase, axons degenerate. Gliosis may be present in older lesions.[web.archive.org] Myelin breakdown, foamy macrophages, and occasional lymphocytes are characteristic, predominantly in a perivascular location.[web.archive.org]

  • Goiter

    Fluid colloid, bland epithelial cells and histiocytes - Pigmented and vacuolated macrophages admixed with bland epithelial cells and bare nuclei.[eurocytology.eu] Pigmented and vacuolated macrophages, bland follicular cells - Pigmented macrophages with bland follicular cells and bare nuclei in the background.[eurocytology.eu] Pigmented macrophages and few small epithelial cells which appear hypofuctioning (small, hyperchromatic nuclei with scanty, denser cytoplasm.[eurocytology.eu]

  • Puerperium

    AF macrophages of fetal origin invade the maternal uterus near term. ( A ) AF macrophages are fetal in origin. β-gal staining was detected in cytoplasmic vacuoles of macrophages[ncbi.nlm.nih.gov]

  • Birth

    AF macrophages of fetal origin invade the maternal uterus near term. ( A ) AF macrophages are fetal in origin. β-gal staining was detected in cytoplasmic vacuoles of macrophages[ncbi.nlm.nih.gov]

  • Toxoplasmosis

    CD40 induces macrophage anti- Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes. J. Clin.[dx.doi.org] macrophages.[dx.doi.org] Virulent Toxoplasma gondii evade immunity-related GTPas-mediated parasite vacuole disruption within primed macrophages. J. Immunol. 182, 3775–3781 (2009).[dx.doi.org]

  • Pulmonary Edema

    There were several degranulated vacuoles in the cytoplasm of the neutrophil.[ncbi.nlm.nih.gov] In another case, infiltration of neutrophils and macrophages, proliferation of type II pneumocytes, and numerous red blood cells were also observed in alveolar air space.[ncbi.nlm.nih.gov]

  • Infectious Colitis

    Bacteria enter membrane-bound vacuoles (phagosomes) inside epithelial cells and macrophages where they replicate ( 235 ).[abdominalkey.com]

  • Carpal Tunnel Syndrome

    On electron microscopy, macrophages with membrano-vacuolated inclusion zebra bodies were seen. Both patients had an uneventful recovery with symptomatic improvement.[ncbi.nlm.nih.gov]

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