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59 Possible Causes for Vacuolated Monocytes

  • Common Cold

    , acts as a chemoattractant for neutrophils and monocytes, and has a defined vitamin D–dependent mechanism. 39 , 40 Pathogenic antigens interact with toll-like receptors on[dx.doi.org] […] mechanism for the inverse association between serum 25(OH)D level and URTI. 14 The only known human cathelicidin, hCAP-18 (LL-37), enhances microbial killing in phagocytic vacuoles[dx.doi.org]

  • Alcohol Abuse

    […] also due to copper deficiency, hematogones, lipid storage diseases, lipid granulomas, monocytes, Mott cells Back to top[pathologyoutlines.com] […] other servers : Marrow plasma cell has dense aggregate of iron Iron laden organelle in upper cell may correspond to microscopic plaque Differential diagnosis Cytoplasmic vacuoles[pathologyoutlines.com]

  • Pediatric Crohn's Disease

    Neutrophil-mediated clearance of mucosal microbes would prevent activation and recruitment of monocytes/macrophages.[web.archive.org] Neutrophil function in CD Neutrophils act as a first line defense at the mucosal-microbial interface by killing and digesting bacteria within phagocytic vacuoles.[web.archive.org]

  • Meningoencephalitis

    E. chaffeensis , the pathogen that causes human monocytic ehrlichiosis, predominantly infects monocytes and tissue macrophages ( Figure 27 ).[doi.org] The organisms multiply in cytoplasmic membrane-bound vacuoles, forming tightly packed clusters of bacteria called morulae.[doi.org]

  • Leukemia

    Small vacuoles are occasionally found in the cytoplasm, which does not necessarily indicate a monocytic change.[web.archive.org]

  • Crohn's Disease

    Neutrophil-mediated clearance of mucosal microbes would prevent activation and recruitment of monocytes/macrophages.[web.archive.org] Neutrophil function in CD Neutrophils act as a first line defense at the mucosal-microbial interface by killing and digesting bacteria within phagocytic vacuoles.[web.archive.org]

  • Kostmann Syndrome

    Myelogram is characteristic: only fissile neutrophil cells, promyelocytes and / or myelocytes are retained, the number of eosinophils and monocytes is increased.[m.iliveok.com] In promyelocytes, there are atypical nuclei, large azurophilic granules and vacuoles in the cytoplasm. Without special treatment, patients died before 2-3 years.[m.iliveok.com]

  • Myelodysplasia

    , duplication of nuclear membrane and nuclear blebs Maturing neutrophils show decreased primary and secondary granules of abnormal size and shape Monocytes show increased[pathologyoutlines.com] […] granulocytic lineage ( Am J Clin Path 2003;120:854 ) Electron microscopy description Same findings as AML Erythroid cells show unusual shapes, redundant cell membranes, large vacuoles[pathologyoutlines.com]

  • Chronic Myelomonocytic Leukemia

    A - Presence of blastic cells in peripheral blood; B and C - Vacuolated monocytes with lobular or nuclear chromatin alterations and the presence of young cells of monocytic[ncbi.nlm.nih.gov] […] cytoplasmic vacuoles Promonocytes and monocytes, neutrophils and erythroid precursors Stains: Alpha naphthyl acetate and methyl green stains (nonspecific esterase) Images[pathologyoutlines.com] As previously demonstrated, the patient presented granulocytes with dysplastic characteristics, such as hypogranular neutrophils and hypersegmented nuclei; vacuolated monocytes[ncbi.nlm.nih.gov]

  • Reactive Arthritis

    Replicated bacteria in HLA-B27 monocytic cells were located within unique vacuoles rather than disturbing host endocytosis.[ncbi.nlm.nih.gov]

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