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305 Possible Causes for Vacuolated Neurons

  • Neuropathy

    Bortezomib-induced changes were also observed in dorsal root ganglia (DRG) neurons, being represented by satellite cell intracytoplasmatic vacuolization due to mitochondrial[bloodjournal.org] Bortezomib-induced changes were also observed in dorsal root ganglia (DRG) neurons and they were represented by satellite cell intracytoplasmatic vacuolization due to mitochondrial[haematologica.org]

  • Alzheimer Disease

    Some cells contained RER and neurosecretory vesicles, suggesting a neuronal origin.[doi.org] However, in cells with extensive vacuolization it was not possible to identify ultrastructural markers indicative of cellular origin.[doi.org] Neurons of PDAPP tg mice that were not associated with plaques showed no neurofibrillary tangles (NFT) or evidence of intraneuronal PHF formation. Fig. 11.[doi.org]

  • Stroke

    Microscopic evaluation during the first 24 to 48 hours discloses anoxic neurons, vacuolization of the white matter due to disentanglement of swellings of myelin and axon.[symptoma.com]

  • Epulis

    Histological analysis showed that the tumor consisted of spindle-shaped and polygonal cells with hyperchromatic nuclei, and intracytoplasmic vacuoles and mitotic figures were[ncbi.nlm.nih.gov] Immunohistochemical staining revealed that the tumor cells were positive for factor VIII-related antigen, CD31, αSMA, and vimentin, but negative for pancytokeratins, S100 protein, neuron-specific[ncbi.nlm.nih.gov]

  • Skin Cancer

    At autopsy, the brains of the 44 yr XP-A and the 45 yr XP-D patients were profoundly atrophic and characterized microscopically by diffuse neuronal loss, myelin pallor and[ncbi.nlm.nih.gov] Unlike the XP-A patient, the XP-D patient had a thickened calvarium, and the brain showed vacuolization of the neuropil in the cerebrum, cerebellum and brainstem, and patchy[ncbi.nlm.nih.gov]

  • Intestinal Pseudo-Obstruction

    […] swelling, vacuolation, and clubbing in the myenteric plexus on silver staining.[gut.bmj.com] […] were interpreted as being secondary to the more prominent neural abnormality as described in 1985. 40 Patient 10 had gross changes of nerve cell loss and degeneration, with neuronal[gut.bmj.com]

  • Angiocentric Glioma

    neuronal tumors subcortical cluster of cystic-like lesions[radiopaedia.org] […] signal on FLAIR minimal surrounding edema perivascular spaces total nulling on the FLAIR sequence ganglioglioma / gangliocytoma usually enhance well defined multinodular and vacuolating[radiopaedia.org]

  • Frontal Lobe Neoplasm

    neuronal tumors (MVNT) which are however in the juxtacortical white matter, rather than in the cortex 7.[radiopaedia.org] […] astrocytomas and ganglioglioma young children dural involvement prominent large often multiple lesions Importantly the 'bubbly' appearance can be seen also in multinodular and vacuolating[radiopaedia.org]

  • Brain Stem Infarction

    Microscopical examination in the first 24 to 48 hours reveals anoxic neurons , pallor of staining and vacuolization of the white matter due to unraveling of myelin, and axonal[neuropathology-web.org]

  • Waisman Syndrome

    , alopecia, and sclerosing cholangitis 607626 CLDN19 1p34.2 Hypomagnesemia 5, renal, with ocular involvement 248190 CLN3 16p11.2 Ceroid lipofuscinosis, neuronal, 3 204200[institutobernabeu.com] […] hypercalciuric nephrocalcinosis 308990 CLCN7 16p13.3 Osteopetrosis, autosomal dominant 2 166600 Osteopetrosis, autosomal recessive 4 611490 CLDN1 3q28 Ichthyosis, leukocyte vacuoles[institutobernabeu.com]

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