Valvular Defects: Causes & Reasons

Possible Causes for Valvular Defects

Eur J Paediatr Neurol 2015 Nov 4;19(6):711-5. Epub 2015 Aug 4. Sackler Faculty of Medicine, Tel-Aviv University, P.O. 39040, Ramat-Aviv, Tel-Aviv, 69978, Israel; Raphael Recanati Genetic Institute, Rabin Medical Center Beilinson Campus and Schneider Children's Medical Center of Israel, Derech Ze'ev Jabotinsky 39, Petah[…] [pubfacts.com]

Noonan Syndrome 3

Note low set, posteriorly rotated, and abnormally formed ear. [6] Heart [ edit ] Up to 85% of people with NS have one of these heart defects: Pulmonary valvular stenosis [en.wikipedia.org]

valvular pulmonary stenosis, often had a characteristic physical appearance, with short stature, webbed neck, wide spaced eyes, and low-set ears. [en.wikipedia.org]

50–60%) Septal defects: atrial (10–25%) or ventricular (5–20%) Hypertrophic cardiomyopathy (12–35%) Lungs [ edit ] Restrictive lung function has been reported in some patients [en.wikipedia.org]

Carbon Monoxide -- Teratogenic Agent

[…] diethylstilbestrol Serious genital malformation Testicular atrophy in male Fetal masculinization in female Vaginal carcinoma of female offspring Lithium Cardiovascular anomalies mainly valvular [slideplayer.com]

[…] heart defect involving tricuspid valve Ebstein's anomaly ACE inhibitors captopril, enalapril Fetal & neonatal anurnia Renal damage Fetal hypotension, hypoperfusion - growth [slideplayer.com]

[…] malformation Finasteride Used in prostatic hypertrophy Abnormal development of genitalia of male fetuses 21 Teratogenesis of drugs Valproic acid Antiepileptic drug Neural tube defect [slideplayer.com]

Immune Hydrops Fetalis

Defect AR 99.98 4 of 4 PMM2 Congenital Disorder Of Glycosylation Type Ia AR 100 127 of 129 PPP1CB Noonan Syndrome-like Disorder With Loose Anagen Hair AD 99.87 12 of 12 PRKCD [igenomix.es]

NA of NA PKLR Elevated Adenosine Triphosphate Of Erythrocytes, Hemolytic Anemia Due To Red Cell Pyruvate Kinase Deficiency AD,AR 100 283 of 285 PLD1 Developmental Cardiac Valvular [igenomix.es]

Ehlers-Danlos Syndrome Cardiac-Valvular Type

defects comprising mitral and/or aortic valve insufficiency.Visit the Orphanet disease page for more resources. [malacards.org]

easy bruisability, atrophic scar formation, joint hypermobility and cardiac valvular defects comprising mitral and/or aortic valve insufficiency. [rarediseases.info.nih.gov]

Congenital heart defects included bicuspid aortic valve (two), pulmonary valvular stenosis (one), ventricular septal defect (two), and an atrial septal defect (one). [annals.org]

FLNB-Related Disorder

Defect AR 99.98 4 of 4 PMM2 Congenital Disorder Of Glycosylation Type Ia AR 100 127 of 129 PPP1CB Noonan Syndrome-like Disorder With Loose Anagen Hair AD 99.87 12 of 12 PRKCD [igenomix.es]

NA of NA PKLR Elevated Adenosine Triphosphate Of Erythrocytes, Hemolytic Anemia Due To Red Cell Pyruvate Kinase Deficiency AD,AR 100 283 of 285 PLD1 Developmental Cardiac Valvular [igenomix.es]

Terminal 4q Deletion Syndrome

defects, piebaldism, genitourinary malformations, adnexal tumors and other anomalies. [ncbi.nlm.nih.gov]

[…] hypertelorism, cleft palate, short nose with broad bridge, small eyes), mental retardation and anomaly of fifth finger with hooked/volar nail.[7–15] Sometimes, there may be cardiac (valvular [ncbi.nlm.nih.gov]

[…] cleft palate, short nose with broad bridge, small eyes), mental retardation and anomaly of fifth finger with hooked/volar nail.[ 7 – 15 ] Sometimes, there may be cardiac (valvular [ncbi.nlm.nih.gov]

Congenital Pulmonary Valve Stenosis

Physiologic and anatomic considerations in congenital tricuspid valvular defects. Circulation 26:723–724, 1962 Google Scholar 6. [link.springer.com]

Pulmonic valvular stenosis may occur in as many as 30% of all patients who have other congenital heart defects. [emedicine.medscape.com]

Valvular pulmonary stenosis means that the leaflets, or "flaps," of the pulmonary valve are abnormal. [pted.org]

Cardio-Facio-Cutaneous Syndrome Type 4

The most commonly observed cardiac anomalies are pulmonic stenosis and other valvular defects, septal defects, hypertrophic cardiomyopathy, and arrhythmia. [invitae.com]

Adams-Oliver Syndrome Type 1

Cardiopulmonary complications such as valvular defects, stenotic lesions of left heart, cardiomyopathy, heart block, malformation of pulmonary vessels, and progressive pulmonary [advbiores.net]

[…] associated with valvular pulmonary stenosis. [malacards.org]

56 Fryns JP...van den Berghe H 1424238 1992 23 Congenital heart defect in a Japanese girl with Adams-Oliver syndrome: one of the most important complications. 56 Ishikiriyama [malacards.org]

Adams-Oliver Syndrome Type 6

Cardiopulmonary complications such as valvular defects, stenotic lesions of left heart, cardiomyopathy, heart block, malformation of pulmonary vessels, and progressive pulmonary [advbiores.net]

Shone Syndrome

supravalvular mitralring, valvular mitral stenosis by a parachute mitral valve, subaortic stenosis and aortic coarctation.This entity commonly curses with its incomplete [doaj.org]

including supravalvular mitral membrane, valvular mitral stenosis (MS) by a parachute mitral valve, subaortic stenosis, and aortic coarctation. [rcvmonline.com]

Shone’s Complex (also known as Shone’s Syndrome, Disorder, or Anomaly) is a rare congenital heart disease consisting of multiple left heart obstructive defects: 1. [pted.org]

Disproportionate Short Stature - Ptosis - Valvular Heart Lesions

Pulmonary stenosis Right ventricular outflow tract obstruction is valvular in 90% of cases and suprvalvar or subvalvar in 10%. [pharmaexpress.net]

Note low set, posteriorly rotated, and abnormally formed ear. [6] Heart [ edit ] Up to 85% of people with NS have one of these heart defects: Pulmonary valvular stenosis [en.wikipedia.org]

[…] have also been described. [2] Frequently associated are pulmonary valvular stenosis, secundum atrial septal defects (ASD), hypertrophic cardiomyopathy (HCM) and partial atrio [heartindia.net]

Karandikar-Maria-Kamble Syndrome

[…] congenital sucrase-isomaltase deficiency congenital syphilis + congenital toxoplasmosis cryptophthalmia + Deafness, Nephritis, Anorectal Malformation developmental cardiac valvular [rgd.mcw.edu]

defect epidermolysis bullosa with congenital localized absence of skin and deformity of nails fibroepithelial polyp of the anus gastroschisis + gonorrhea + hemorrhoid + hypospadias [rgd.mcw.edu]

Cohen Syndrome

Cardiac Cardiac defects reported in Cohen syndrome include decreased left ventricular function with advancing age, valvular defects (such as a floppy mitral valve and mitral [cureus.com]

Tetrasomy X

[…] or valvular cardiac defects. [en.wikipedia.org]

Several cardiac defects have also been reported, including ventricular/atrial septal defects, atresia, hypoplastic right heart syndrome, patent ductus arteriosus, and conotruncal [en.wikipedia.org]

Platelet-Type Bleeding Disorder 18

or increased shear stress due to valvular defects or mechanical vascular devices (Tiede et al... [readbyqxmd.com]

Both qualitative and quantitative defects occur, due to antibody-mediated clearance or functional interference, increased proteolysis, absorption to malignant cells or platelets [readbyqxmd.com]

Mitral Atresia

These include patent ductus arteriosus, coarctation of the aorta, transposition of the great arteries, pulmonary stenosis, shunt defects, cor triatriatum, chamber, and valvular [ncbi.nlm.nih.gov]

cor triatriatum, chamber, and valvular anomalies. [ncbi.nlm.nih.gov]

[…] often associated with other cardiac malformation such as patent ductus arteriosus, coarctation of the aorta, transposition of the great arteries, pulmonary stenosis, shunt defects [ncbi.nlm.nih.gov]

Atrial Septal Defect - Atrioventricular Conduction Defects Syndrome

valvular defects (mitral and tricuspid). [doctortipster.com]

[…] of the aorta, 13.3% for valvular aortic stenosis, and 2.8% for primum atrial septal defect [11]. [wikigenes.org]

In several patients, ASD may be isolated or associated with other cardiac diseases such as valvular stenosis, conduction defects, or atrial arrhythmia, and may require additional [file.scirp.org]

Acute Rheumatic Endocarditis

Mitral = because bacterial vegetation embolizes into systemic circulation - can obstruct cerebral vasculature or splenic vasculature Valvular defect produced by acute vs. [quizlet.com]

Patients with prior valvular defects or those with an artificial heart valve are more likely to develop endocarditis following lip or tongue piercing. [atsu.edu]

Acute phase: a. primary rheumocarditis without valvular involvement. b. recurrent rheumocarditis with cardiac defect c. rheumatic fever without obvious cardiac involvement [intranet.tdmu.edu.ua]

X-linked Cardiac Valvular Dysplasia

Congenital tricuspid incompetence due to valvular dysplasia is a defect involving the leaflets (normally inserted on the ring) the cordae tendinae and papillary muscles of [ncbi.nlm.nih.gov]

Approximately 3 percent of the population has a heart valve defect, only a small fraction of which are associated with X-linked cardiac valvular dysplasia. [ghr.nlm.nih.gov]

(Medical Encyclopedia) [ Read More ] Heart Valve Diseases Also called: Valvular heart disease Your heart has four valves. [icdlist.com]

Endocardial Cushion Defect

Additional findings in complete endocardial cushion defects relate to the ventricular septal defect and valvular insufficiency. [chdbabies.com]

Patients with septal defects and mitral valve insufficiency develop CHF early in life, with high rates of morbidity and mortality if the valvular insufficiency is pronounced [emedicine.com]

When a complete endocardial cushion defect is present, a large ventricular septal defect as well as valvular insufficiency may develop, resulting in volume overload of both [chdbabies.com]

Congenital Pulmonary Valve Insufficiency

Physiologic and anatomic considerations in congenital tricuspid valvular defects. Circulation 26:723–724, 1962 Google Scholar 6. [link.springer.com]

Surgery and procedures: Balloon dilatation Minimally – Invasive Atrial Septal defect closure. Minimally – Invasive valve repair and replacement. [nursingexercise.com]

[…] pulmonic regurgitation is rare and most often results from an isolated congenital defect involving dilation of the pulmonary artery and pulmonary valve annulus. [msdmanuals.com]

Ebstein Malformation

A large ventricular septal defect below the single valvular structure leads to a mixture of blood from both sides being taken into systemic circulation. [pinterest.it]

In the first one, the ventricular septal defect was corrected with a valvular patch, a pleat of the atrialized portion, and a tricuspid valvuloplasty. [pesquisa.bvsalud.org]

However, a right-to-left shunt was still present across the atrial septal defect. [eplabdigest.com]

Congenital Mitral Stenosis

defects ) Diastolic murmur typically heard best at the 5 th left intercostal space at the mid-clavicular line (the apex) Loud first heart sound (S 1 ) Opening snap of the [amboss.com]

1] This malformation is characterized by progressive worsening of valvular defect, which could be regurgitation, stenosis or both. [jcecho.org]

(Medical Encyclopedia) [ Read More ] Heart Valve Diseases Also called: Valvular heart disease Your heart has four valves. [icdlist.com]

Branch Pulmonary Artery Stenosis

The most common form of PS is valvular which is congenital in origin and usually occurs as an isolated sporadic defect. [heartdiseaseandpregnancy.com]

PPS may be associated with other congenital heart anomalies such as valvular PS, atrial septal defect (ASD), VSD, or patent ductus arteriosus (PDA); 20% of the patients with [emedicine.medscape.com]

PPS may be associated with other congenital heart anomalies such as valvular PS, atrial septal defect, ventricular septal defect, or patent ductus arteriosus. 20% of the patients [medicina-interventionala.ro]

Mosaic Trisomy 18

Frequent congenital heart anomalies in trisomy 18 include valvular defects, patent foramen ovale and ventricular septal defect. [wjpch.com]

X-Linked Neurodegenerative Syndrome Type Hamel

Cardiac involvement can also include atrial septal defect, valvular insufficiency, and pre-excitation syndrome. [zenodo.org]

Rare myopathic or neurologic involvement has been reported, but these features are not consistently part of the disorder and may be related to other genetic defects. [zenodo.org]

Ehlers-Danlos Syndrome Type 4

defects and tissue fragility. [path.upmc.edu]

Form Joint hypermobility, skin hyperextensibility, cardiac valvular defects Recessive COL1A2 Comprehensive EDS Panel Periodontal (EDS type VIII) Periodontitis, gingival recession [uwcpdx.org]

defects. [nature.com]

Chronic Right-Sided Congestive Heart Failure

defects, wall motion abnormalities Coronary angiography (left heart catheterization): indicated to detect/confirm CHD and possible percutaneous coronary intervention Right [amboss.com]

Congenital heart defects. Some people who develop heart failure were born with structural heart defects. Valvular heart disease. [mayoclinic.org]

Valvular heart disease Viruses Alcohol use Tobacco use Obesity Irregular heartbeats ( 5 ) Life Expectancy After Heart Failure Your life expectancy after heart failure depends [everydayhealth.com]