Variable-severity: Causes & Reasons

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Possible Causes for variable severity

Common Cold

After accounting for possible confounding variables, cold severity and duration were significantly lower in those reporting perfect CARE scores. [ncbi.nlm.nih.gov]

After accounting for possible confounding variables, cold severity and duration were significantly lower in those reporting perfect CARE scores (p 0.037 and p 0.017 respectively [ncbi.nlm.nih.gov]

In those with perfect CARE scores, cold duration was shorter (mean 7.10 days versus 8.01 days), and there was a trend toward reduced severity (mean area under receiver-operator [ncbi.nlm.nih.gov]

Acute Gastroenteritis

The aim of the present report is to describe haemoglobin concentration, a key variable of the ABP, during acute gastroenteritis in athletes. 5 athletes with severe gastroenteritis [ncbi.nlm.nih.gov]

[…] a clear algorithm for searching dehydration markers and techniquesfor proper replacement of fluid losses depending on the severity. [kremlin-medicine.ru]

[…] contributing to risk included age ( 12 months), frequent stools ( eight/day), vomiting ( twice/day), and severe undernutrition. [adc.bmj.com]

Hand-Foot-Genital Syndrome

severity. [ncbi.nlm.nih.gov]

Affected males may have penile hypospadias of variable severity with or without chordee, short penis, or bifid scrotum. [link.springer.com]

[…] include a displaced urethral opening and malposition of ureteral orifices in the bladder wall; affected males may have hypospadias (ventrally misplaced urethral opening) of variable [ncbi.nlm.nih.gov]

Acute Bronchitis

Other efficacy variables were percentage BSS systemic sign efficacy after treatment and change in individual BSS parameters after treatment. [ncbi.nlm.nih.gov]

The results for the concomitant variables of efficacy support the high superiority of the verum medication compared to placebo. [ncbi.nlm.nih.gov]

[…] another condition that impairs lung function) Sore throat Runny or stuffy nose Headache Muscle aches Extreme fatigue Physical examination findings in acute bronchitis are variable [emedicine.medscape.com]

Bronchitis

[…] and may include the following: Diffuse wheezes, high-pitched continuous sounds, and the use of accessory muscles (in severe cases) Diffuse diminution of air intake or inspiratory [emedicine.medscape.com]

Oculootoradial Syndrome

Upper limbs may be severely malformed. Extraocular motor disturbances and hearing loss of variable severity have also been reported. [malacards.org]

[…] tissues include eye, ovary and testis, and related phenotypes are hearing impairment and joint stiffness Disease Ontology : 12 A syndrome characterized by radial ray defect of variable [malacards.org]

severity, mixed congenital hearing loss, mild thrombocytopenia, and external ophthalmoplegia that has material basis in heterozygous mutation in SALL4 on chromosome 20q13.2 [malacards.org]

Insect Bite

LOCAL REACTIONS TO BUG BITES AND STINGS: Redness, swelling, and itching Variable severities - usually worse on the hands and face NOT an allergy (unless it spreads beyond [jeffersandmann.com]

Viral Upper Respiratory Tract Infection

Several viruses, from variable families, cause upper respiratory infections which, although generally underestimated due to their typically self-limiting nature, underlie [link.springer.com]

It can be caused by members of several families of viruses; the most common are the more than 100 serotypes of rhinoviruses. 3. [slideshare.net]

DEFINITION Acute, self-limiting viral infection of the upper respiratory tract, involving, to variable degrees, sneezing, nasal congestion and discharge (rhinorrhea), sore [slideshare.net]

Vitamin D Deficiency

All 4 diets were rachitogenic after a variable period of exposure. Rickets was severe and developed easily in dogs that grew well on the rachitic diets. [doi.org]

However, nowadays, several studies have reported conflicting results on its biological variability during the natural cycle of a woman. [pulsus.com]

Several sources of variability have been identified, including body mass index (BMI), which is inversely associated with change in 25OHD. [doi.org]

Upper Respiratory Infection

Symptom severity and viral load (log viral copies/mL) were compared by t -test. [bmcinfectdis.biomedcentral.com]

However, firm recommendations regarding routine use in healthy individuals are difficult to make, due to variability inherent in the course of URIs; the variability in dosing [emedicine.medscape.com]

The measures of 'severity' that have been used in the included trials are variable. [doi.org]

Urinary Tract Infection

Several challenges exist in the evaluation of urinary symptoms in the elderly patient. [ncbi.nlm.nih.gov]

Results of adherence monitoring were highly variable and several studies reported participants withdrawing because of the unpalatable or intolerable nature of the cranberry [doi.org]

Symptoms of UTI are variable; problems are encountered in the collection, testing, and interpretation of urine specimens; and results of urinalysis are often misinterpreted [ncbi.nlm.nih.gov]

Vaginitis

Like the Nugent scoring system used for grading BV, the AV score may indicate normal, intermediate, or severe AV ( 27 ). Table 2. [frontiersin.org]

Lactobacillary grades are the basis for a composite score to which the following four variables have been added: (a) proportional number of lactobacilli; (b) the presence [frontiersin.org]

Acute Alcohol Intoxication

Genetic predisposition and personal history of severe withdrawal appear to be major contributors to the development of alcohol withdrawal symptoms. 35 Clinical Pesentation [emsreference.com]

The mortality of ethylene glycol intoxication is variable, ranging from 1 to 22% ( 8, 10, 78 ). [cjasn.asnjournals.org]

Several randomised controlled trials have investigated early laparoscopic cholecystectomy versus delayed laparoscopic cholecystectomy [74–82]. [wjes.biomedcentral.com]

Vitamin B12 Deficiency

However, the rate at which B12 levels may change when dietary intake is low depends on the balance between several variables. [en.wikipedia.org]

After therapy, recovery was variable, with some children remaining moderately or severely retarded [ 13, 17 – 19 ]. [ncbi.nlm.nih.gov]

Spurious associations may be seen with variables related to the utilization of medical services, and case-control studies may not be able to completely control for such confounding [doi.org]

Cystitis

Outlook IC is a condition with a variable course. For many people, the severity of symptoms fluctuates. For some, the condition goes into periods of remission. [emedicinehealth.com]

Acute Cystitis

Results of adherence monitoring were highly variable and several studies reported participants withdrawing because of the unpalatable or intolerable nature of the cranberry [dx.doi.org]

Constipation

including tropical sprue, parasitic infection, common variable immunodeficiency, human immunodeficiency virus (HIV) enteropathy, and drug and enteropathy induced by food [worldgastroenterology.org]

While the histological changes seen in celiac disease are considered to be characteristic, they are not pathognomonic, as similar changes can be seen in several other conditions [worldgastroenterology.org]

Rosacea

The primary outcome variable for this study (Investigator Global Assessment of Rosacea Severity Score) was assessed by investigators who were blinded to randomisation throughout [doi.org]

They are usually prescribed for 6–12 weeks, and this can be variable, depending on the severity of the rosacea. [racgp.org.au]

[…] in severity of rosacea, for example, a change from ‘severe’ to ‘moderate’, or from ‘moderate’ to ‘mild’. [doi.org]

Hypersensitivity

CD CD is an immune-mediated chronic enteropathy with a wide range of presenting manifestations of variable severity. [web.archive.org]

It covers many different clinical phenotypes with variable onset and severity. [waojournal.biomedcentral.com]

It covers many different phenotypes and the major symptoms (sneezing, running nose, and stuffy nose) with variable intensity according to the triggers/causes. [waojournal.biomedcentral.com]

Anemia

[…] is an important variable limiting the otherwise favorable natural history of patients with lower risk disease. [doi.org]

The prevalence of anemia among adolescent girls is 47.9%, of which 47.7% have mild anemia, 51.7% have moderate anemia, and 5.7% have severe anemia, which reveals that anemia [hindawi.com]

On the basis of the AMA, 138 (87.9%) of 157 patients were mildly, moderately, or severely malnourished (mean, 24.41 9.86 cm 2). [ncbi.nlm.nih.gov]

Musculoskeletal Lower Back Pain

Cut-off points for mild, moderate, and severe pain on the numeric rating scale for pain in patients with chronic musculoskeletal pain: variability and influence of sex and [scielo.br]

Cases of MAT complicated by severe cardiorespiratory failure are rare and require medical treatment which relies mainly on amiodarone and other class anti-arrhythmic drugs [latunisiemedicale.com]

Clinical tolerability of MAT is variable depending on the ventricular rhythm and its clinical manifestations in children vary from a benign asymptomatic arrhythmia to sudden [latunisiemedicale.com]

Iron Deficiency

Age at presentation, disease severity, and response to iron supplementation are highly variable, even within families, with a few patients responding to oral iron but most [emedicine.com]

Gingivitis

[…] are higher in more severe gingivitis and periodontitis. [aem.asm.org]

Ordinal regression models were used to assess the association of the outcome (gingivitis severity ranging from gingival index score zero to score 3) with the explanatory variables [emro.who.int]

(e.g., disease severity) as inputs, which allowed the identification of differentially abundant species. [aem.asm.org]

Adenovirus Infection

As mentioned, although ribavirin has been used as treatment of adenoviral infections, its clinical success has been variable. [infectiousdiseaseadvisor.com]

In addition, ribavirin is inactive against several serotypes of adenovirus, and its use is, therefore, not generally recommended for adenoviral infections. [infectiousdiseaseadvisor.com]

Insomnia

There were no significant associations between spindle density and changes in the Insomnia Severity Index or polysomnography variables over time. [ncbi.nlm.nih.gov]

RESULTS: Moderate to severe NRS was the first-level predictor of all 3 daytime variables. [ncbi.nlm.nih.gov]

The outcome measure was the Insomnia Severity Index (ISI). [ncbi.nlm.nih.gov]

Autosomal Dominant Optic Atrophy and Cataract

severity, followed by a late anterior and/or posterior cortical cataract. [orpha.net]

[…] cataract (ADOAC) is a form of autosomal dominant optic atrophy (ADOA; see this term) characterized by an early and bilateral optic atrophy leading to insidious visual loss of variable [orpha.net]

Menopause

Some women experience only minimal symptoms, while others may have severe and troublesome symptoms associated with menopause. [medicinenet.com]

Women are very variable in their tolerance of discomfort, often tolerating quite severe symptoms before they will even consider treatments. [menopause.org.au]

Some of the most common symptoms are hot flashes, vaginal dryness, and mood swings, but the extent to which women suffer from all of these is variable. [medicinenet.com]

Ovarian Cyst

Physical findings associated with endometriosis are variable and are dependent on the severity and location of the disease. [emedicine.medscape.com]

This may be intermittent, or can be severe, sudden, and sharp. [emedicinehealth.com]

This may be intermittent, or can be severe, sudden, and sharp Irregular menstrual periods A feeling of lower abdominal or pelvic pressure or fullness Chronic pelvic pain or [emedicinehealth.com]

Acne Vulgaris

The analysis evaluated the link between a moderate to severe acne and anthropometric variables, family history and dietetic factors. [ncbi.nlm.nih.gov]

Objective To assess the complex interconnection between dietetic variables and acne. [doi.org]

The course of acne vulgaris is variable, persistence being ordinarily directly related to the severity of the lesions, although changes of climate and emotional stress may [britannica.com]

Depression

Results Brooding (p .005) was positively associated with the severity of problem gambling after adjusting for reflection, depressive symptoms, and sociodemographic variables [ncbi.nlm.nih.gov]

The course of the disorder is extremely variable from person to person; it may be mild or severe, acute or chronic. [britannica.com]

Several antidepressant drugs are available for use under the supervision of a physician. [nationalmssociety.org]