Vertical Gaze Palsy: Causes & Reasons

Possible Causes for Vertical Gaze Palsy

Supranuclear vertical gaze palsy and increased age at symptom-onset distinguished PSP from MSA. [doi.org]

We describe a woman with a 13-year history of postural instability, vertical gaze palsy and dopa-responsive parkinsonism - a clinical profile that corresponds to progressive [ncbi.nlm.nih.gov]

Supranuclear vertical gaze palsy, gait instability and the absence of delusions distinguished PSP from diffuse Lewy body disease. [doi.org]

Neurologic Manifestation of Whipple Disease

In our case after the confirmation of possible CNS WD (fever of unknown origin, chronic migratory arthralgias, unexplained lymphadenopathy, supranuclear vertical gaze palsy [benthamopen.com]

gaze palsy, and occasionally, rhythmic movements of the limbs (see video in Media below). [eyewiki.aao.org]

She still suffered from vertical gaze palsy and sixth cranial nerve paresis on the left side. [dovepress.com]

Parinaud Syndrome

Vertical gaze palsy. Neurology Medlink. released July 19, 2001; last updated March 5, 2014. ↑ Kato Isao, et al. [eyewiki.aao.org]

Only 65.0% patients had the classical triad of vertical gaze palsy, convergence-retraction nystagmus and light-near dissociation. [ncbi.nlm.nih.gov]

Vertical gaze palsy may thus result from lesions to the medial longitudinal fasciculus, the posterior commissure or the midbrain itself. [symptoma.com]

Pineal Gland Neoplasm

Other features relating to these tumours include: [ 3 ] Parinaud's syndrome - vertical gaze palsy ± pupillary or oculomotor nerve paresis. [patient.info]

Oculomotor Nerve Paralysis

Vertical gaze palsy is the inability to look up or down. It affects both eyes. Pupils are often unequal but fixed and there is usually no diplopia. [patient.info]

Signs of CN IV palsy 2 • acute onset of vertical diplopia in the absence of ptosis • characterised by a head posture • features of nuclear, fascicular and peripheral CN IV [cmej.org.za]

More rostral spread may affect prenuclear structures for vertical gaze. [neuroophthalmology.ca]

Intracranial Hypertension

Vertical gaze palsy is the result of pressure on the roof midbrain, where vertical gaze centers are located. [clinicaladvisor.com]

Gaze abnormalities, including an inability to move the eyes vertically up and evidence of bilateral lateral gaze palsy. 3. [clinicaladvisor.com]

Bilateral horizontal gaze palsy is the result of stretch-related VIth nerve injury from increased ICP. [clinicaladvisor.com]

Suprasellar Tumor

This phenomenon is caused by involvement of midbrain structures adjacent to the pineal GCT and is characterised by vertical gaze palsy, nystagmus on convergence and pupillary [tandfonline.com]

Pineal Gland Dysfunction

[…] eye movements Problems with the visual pathways in pineal tumors: Accommodation deficiency Oculomotor nerve palsy Failure of downward gaze Visual field disturbance (mass [pedsoncologyeducation.com]

[…] pretectum - eye symptoms are common The pretectum: Includes the ocular motor centre and pupillary control centre Between the thalamus and the midbrain Responsible for mediating vertical [pedsoncologyeducation.com]

Primary Progressive Multiple Sclerosis

We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…] [ncbi.nlm.nih.gov]

Intracerebral Hematoma

Stroke. 2016 Feb;47(2):350-5. doi: 10.1161/STROKEAHA.115.011295. Epub 2015 Dec 22. Rodriguez-Luna D 1, Stewart T 1, Dowlatshahi D 1, Kosior JC 1, Aviv RI 1, Molina CA 1, Silva Y 1, Dzialowski I 1, Lum C 1, Czlonkowska A 1, Boulanger JM 1, Kase CS 1, Gubitz G 1, Bhatia R 1, Padma V 1, Roy J 1, Subramaniam S 1, Hill MD 1, Demchuk AM 2 ;[…] [ncbi.nlm.nih.gov]

Meningioma

Meningioma (Frontal). (Left) T1-weighted with gadolinium parasagittal MRI; (Middle) T1-weighted axial MRI; (Right) T1-weighted with gadolinium axial MRI. Note the large, well demarcated mass that is dural based and compresses the adjacent frontal lobe. The mass is isointense on T1-weighted images but strongly enhances[…] [casemed.case.edu]

Multiple Sclerosis

Dr. Carla Rossotti (left), a general practitioner, and her health care team leave the home of the their patient, 37-year-old Osvaldo Daniel Martinez. He has the symptoms of a degenerative disease, Rossotti says, but he needs a neurologist's evaluation before he can get proper treatment. Sarah Varney/Kaiser Health[…] [npr.org]

Colloid Cyst of the Third Ventricle

Giant or huge colloid cysts of the third ventricle up to of more than 3 cm in diameter are extremely rare. The patient presented with symptoms of increased intracranial pressure, including headache, vomiting, and papilledema. Computerized tomographic (CT) scan revealed a hypodense, huge colloid cyst of the third[…] [ncbi.nlm.nih.gov]

Nothnagel Syndrome

Vertical gaze palsy, ataxia, sleepiness and even coma, impaired attention and memory. [neurovascularmedicine.com]

Amnestic syndrome and vertical gaze palsy: early detection of bilateral thalamic infarction by CT and NMR. Swanson RA, Schmidley JW. Swanson RA, et al. [pubmed.ncbi.nlm.nih.gov]

Parinaud's Syndrome, also known as dorsal midbrain syndrome, vertical gaze palsy, and Sunset Sign, is an inability to move the eyes up. [ipfs.io]

Classic Progressive Supranuclear Palsy Syndrome

However, muscle atrophy, weakness, evidence of denervation on electromyography, vertical gaze palsy, parkinsonism, gait freezing, aphasia, speech apraxia, or dementia was [okayama.pure.elsevier.com]

Clifford Richardson identified patients in Toronto with a syndrome of supranuclear vertical gaze palsy, pseudobulbar palsy, axial rigidity-in-extension, and cognitive impairment [discovery.ucl.ac.uk]

Vertical gaze palsy is the most distinctive single clinical feature. [patient.info]

Huntington Disease

To save this word, you'll need to log in. Hun·ting·ton's disease | \ ˈhən-tiŋ-tənz- \ variants: or less commonly Huntington disease or Huntington's chorea : a hereditary brain disorder that is a progressive, neurodegenerative condition marked especially by impairments in thinking and reasoning, disturbances of[…] [merriam-webster.com]

Olfactory Groove Meningioma

Loss of olfaction has been considered inevitable in endoscopic endonasal resection of olfactory groove meningiomas. Olfaction preservation may be feasible through an endonasal unilateral transcribriform approach, with the option for expansion using septal transposition and contralateral preservation of the[…] [ncbi.nlm.nih.gov]

Niemann-Pick Disease Type C

The second developed progressive ataxia, accompanied by a vertical gaze palsy, when she was 13. [ncbi.nlm.nih.gov]

Clinical features of this disease include vertical supranuclear gaze palsy, seizures and cataplexy. [ncbi.nlm.nih.gov]

Neurological examination revealed a broad-based ataxic gait, limb dysmetria, downward vertical gaze palsy, brisk lower limb reflexes and ankle clonus, while neuropsychological [ncbi.nlm.nih.gov]

Sellar Tumor with Suprasellar Extension

A truly comprehensive reference for the management of patients with endocrine cancer The new edition of Clinical Endocrine Oncology has been fully revised and extended making it the most comprehensive and up-to-date reference available. Written and edited by leading international experts in the field, it sets the[…] [books.google.com]

Niemann-Pick Disease

Examination showed ataxia, moderate cognitive impairment, and vertical gaze palsy. EEG revealed diffuse slowing and disorganization of background rhythms. [ncbi.nlm.nih.gov]

Classically, children with NPC demonstrate neurological dysfunction with cerebellar ataxia, dysarthria, seizures, vertical gaze palsy, motor impairment, dysphagia, psychotic [clinicaltrials.gov]

Vertical supranuclear gaze palsy may be present. [patient.info]

Myasthenia Gravis

What is myasthenia gravis? Myasthenia gravis is a chronic autoimmune neuromuscular disease that causes weakness in the skeletal muscles, which are responsible for breathing and moving parts of the body, including the arms and legs. The name myasthenia gravis, which is Latin and Greek in origin, means "grave, or[…] [ninds.nih.gov]

Creutzfeldt Jakob Disease

News A urine test for Creutzfeldt-Jakob Disease may be possible Contact the Press Office MRC Talks podcast Network magazine Insight blog Back to listing 3 Oct 2016 Researchers at the MRC Prion Unit at UCL have found that it may be possible to determine whether or not a person has sporadic Creutzfeldt-Jakob[…] [mrc.ukri.org]

Familial Congenital Palsy of Trochlear Nerve

Parinaud's syndrome Parinaud's syndrome, also known as dorsal midbrain syndrome, vertical gaze palsy, and sunset sign, is an inability to move the eyes up and down. [howlingpixel.com]

Parinaud's syndrome (vertical gaze palsy caused by a pineal tumour ). Giant cell arteritis. [patient.info]

The most common ocular motor pattern (Pattern 1, n = 17, 43%) was bilateral horizontal gaze palsy with intact vertical range. [academic.oup.com]

Freeman-Sheldon Syndrome

Homepage Rare diseases Search Search for a rare disease Freeman-Sheldon syndrome Disease definition Freeman-Sheldon syndrome (FSS) is a very rare, multiple congenital contractures syndrome characterized by a microstomia with a whistling appearance of the mouth, distinctive facies, club foot and joint[…] [orpha.net]

Craniofrontonasal Dysplasia

Craniofrontonasal dysplasia X-linked dominant inheritance works differently depending upon whether the mother (left image) or father (right image) is the carrier of a gene that causes a disease or disorder This condition is inherited differently from each parent Specialty Medical genetics Craniofrontonasal[…] [maria-online.com]

Rubinstein-Taybi Syndrome

Reference work entry DOI: https://doi.org/ 10.1007/978-3-540-29676-8_3220 Synonyms Broad thumbs and great toes; Characteristic facies, and mental retardation; Broad thumb-hallux syndrome; RSTS Definition and Characteristics Rubinstein-Taybi syndrome (OMIM #180849) 1 is a rare congenital disorder characterized by[…] [link.springer.com]

Niemann-Pick Disease Type B

[…] supranuclear gaze palsy (VSPG), dysarthria, dysphagia, dystonia, seizures, gelastic cataplexy, and psychiatric disorders. [orpha.net]

Vertical supranuclear gaze palsy may be present. [patient.info]

[…] unexplained neonatal jaundice or cholestasis, isolated unexplained splenomegaly, and progressive, often severe neurological symptoms such as cognitive decline, cerebellar ataxia, vertical [orpha.net]

Kernicterus

Kernicterus (Bilirubin encephalopathy) is an acquired metabolic encephalopathy of the neonatal period. Its etiology and pathogenesis overlap to some extent with HIE. Kernicterus is caused by unconjugated hyperbilirubinemia that develops either as a result of hemolytic disease (Rh incompatibility, hereditary[…] [neuropathology-web.org]

Horizontal Gaze Palsy with Progressive Scoliosis

Neurological examinations revealed remarkable conjugate horizontal but not vertical gaze palsy. [ncbi.nlm.nih.gov]

[…] in one direction. [13] Classification [ edit ] Conjugate gaze palsies can be classified into palsies affecting horizontal gaze and vertical gaze. [en.wikipedia.org]

An even more fundamental distinction is between vertical and horizontal gaze palsies. [medlink.com]

Botulism

Botulinum toxin ingestion leads to a clinical syndrome characterised by cranial nerve palsies, oculobulbar weakness, and descending, symmetrical flaccid paralysis in the absence of fever. Affected patients do not complain of sensory deficits. The diagnosis of botulism is a clinical one, confirmed by the detection of[…] [bestpractice.bmj.com]