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421 Possible Causes for Vertical Gaze Palsy

  • Primary Progressive Multiple Sclerosis

    We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…][]

  • Suprasellar Tumor

    This phenomenon is caused by involvement of midbrain structures adjacent to the pineal GCT and is characterised by vertical gaze palsy, nystagmus on convergence and pupillary[]

  • Progressive Supranuclear Palsy

    Supranuclear vertical gaze palsy and increased age at symptom-onset distinguished PSP from MSA.[] On examination supranuclear vertical gaze palsy with slow horizontal saccades, axial rigidity and bradykinesia were present.[] Supranuclear vertical gaze palsy, gait instability and the absence of delusions distinguished PSP from diffuse Lewy body disease.[]

  • Intracerebral Hematoma

    Abstract An 80-year-old male presented with a chronic encapsulated intracerebral hematoma (CEIH) with surrounding edema under the right frontal lobe manifesting as slow exacerbation of disturbance of orientation and gait. He had a history of cerebral infarction with an asymptomatic cavernous angioma in the right[…][]

  • Intracranial Hypertension

    Vertical gaze palsy is the result of pressure on the roof midbrain, where vertical gaze centers are located.[] Gaze abnormalities, including an inability to move the eyes vertically up and evidence of bilateral lateral gaze palsy. 3.[] Bilateral horizontal gaze palsy is the result of stretch-related VIth nerve injury from increased ICP.[]

  • Meningioma

    Meningioma refers to one oR many tumors that arise in very close contact to the meninges. The meninges are the membranous layers that cover the brain and spinal cord. Symptoms of meningioma are produced via different mechanisms. By irritating the underlying cortex, they can cause seizures. Headaches, weakness,[…][]

  • Neurologic Manifestation of Whipple Disease

    In our case after the confirmation of possible CNS WD (fever of unknown origin, chronic migratory arthralgias, unexplained lymphadenopathy, supranuclear vertical gaze palsy[] gaze palsy, and occasionally, rhythmic movements of the limbs (see video in Media below).[] She still suffered from vertical gaze palsy and sixth cranial nerve paresis on the left side.[]

  • Oculomotor Nerve Paralysis

    Vertical gaze palsy is the inability to look up or down. It affects both eyes. Pupils are often unequal but fixed and there is usually no diplopia.[] More rostral spread may affect prenuclear structures for vertical gaze.[] Signs of CN IV palsy 2 • acute onset of vertical diplopia in the absence of ptosis • characterised by a head posture • features of nuclear, fascicular and peripheral CN IV[]

  • Multiple Sclerosis

    Multiple sclerosis (MS, disseminated sclerosis, encephalomyelitis disseminata) is an inflammatory demyelinating disease of the central nervous system. Multiple sclerosis is divided into the following categories: Relapsing-remitting MS, Secondary progressive MS, Primary progressive MS and Progressive-relapsing MS. Individuals[…][]

  • Parinaud Syndrome

    Only 65.0% patients had the classical triad of vertical gaze palsy, convergence-retraction nystagmus and light-near dissociation.[] Vertical gaze palsy may thus result from lesions to the medial longitudinal fasciculus, the posterior commissure or the midbrain itself.[] Vertical gaze palsy. Neurology Medlink. released July 19, 2001; last updated March 5, 2014. Kato Isao, et al.[]

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