Villous Atrophy: Causes & Reasons

Possible Causes for Villous Atrophy

However, a subset of patients with common variable immunodeficiency (CVID) experience a severe norovirus-associated enteropathy leading to intestinal villous atrophy and malabsorption [ncbi.nlm.nih.gov]

atrophy Villous atrophy may be mild to severe Prominent crypt destruction Crypt destruction not prominent Anti-enterocyte antibody All antibodies generally depressed; humoral [surgpathcriteria.stanford.edu]

Ileal biopsies showed villous atrophy, presence of eosinophils, polymorphonuclear cells, and NLH, which was also found in biopsies of the right colon. Figure 2. [acgcasereports.gi.org]

Syndromic Diarrhea

The amount of villous atrophy does not explain the severity of the diarrhea. [checkorphan.org]

Histopathological analysis of small intestine biopsy shows non-specific villous atrophy with low or no mononuclear cell infiltration of the lamina propria, and no specific [doi.org]

Diagnosis - Tricho-hepato-enteric syndrome Microscopic examination of a biopsy of the small bowel in these patients shows villous atrophy with low or no mononuclear cell infiltration [checkorphan.org]

Congenital Tufting Enteropathy

The differential diagnoses for diseases with persistent diarrhea and villous atrophy that should be ruled out include congenital chloride diarrhea, congenital sodium diarrhea [revistas.unal.edu.co]

Congenital Disorder of Glycosylation Type 1B

He subsequently developed an enteropathy with subtotal villous atrophy on biopsy. [ncbi.nlm.nih.gov]

atrophy, abnormal intestinal permeability and enterocyte lipid transport, associated with abnormal glycosylation of intestinal glycoproteins, diarrhea, vomiting), and kidneys [accessanesthesiology.mhmedical.com]

atrophy 0011473 Vomiting Throwing up 0002013 Showing of 24 | Last updated: 7/1/2019 Making a diagnosis for a genetic or rare disease can often be challenging. [rarediseases.info.nih.gov]

Neonatal Inflammatory Skin and Bowel Disease Type 1

atrophy Abnormality of the cardiovascular system Erythema Hematochezia Abnormality of ... ... [familydiagnosis.com]

Ontology (HPO) Abnormality of blood and blood-forming tissues Eosinophilia Hematochezia Abnormality of head or neck Blepharitis Abnormality of the abdomen Diarrhea Hematochezia Villous [familydiagnosis.com]

Celiac Disease

atrophy. [ncbi.nlm.nih.gov]

Material and methods Forty-one adults suspected of coeliac disease owing to increased density of mucosal γδ+ intraepithelial lymphocytes but normal villous morphology were [doi.org]

The degree of villous atrophy was inversely correlated with age (P < 0.001). Classic symptoms were also associated with more severe villous atrophy. [ncbi.nlm.nih.gov]

Diabetic Enteropathy

This leads to the characteristic villous atrophy of coeliac disease. [nps.org.au]

The diagnosis of celiac disease required histologic evidence of villous atrophy and crypt hyperplasia and a positive antiendomysial antibody test result. [annals.org]

In some there may be persistent villous atrophy, although this is usually mild and improved compared with the pre-treatment appearance. [nps.org.au]

Lymphocytic Gastritis

Fifteen of these 29 cases (52%) showed villous atrophy; all were graded as moderate or severe. [ncbi.nlm.nih.gov]

Four patients with LG, all with villous atrophy, were seropositive for IgA endomysial antibody. [ncbi.nlm.nih.gov]

A proximal small bowel biopsy showed villous atrophy and lymphoplasmacytic infiltration consistent with celiac sprue. [ncbi.nlm.nih.gov]

Malabsorption Syndrome

Sixteen patients had histologically confirmed villous atrophy. [ncbi.nlm.nih.gov]

A statistically significant decrease of lactose and alkaline phosphatase < 3rd percentile was found which coresponded to the degree of intestinal villous atrophy. [ncbi.nlm.nih.gov]

Abdominal lymphoma was suspected, but exploratory laparotomy was normal except for partial villous atrophy of small intestine and slightly enlarged mesenteric lymphnodes which [ncbi.nlm.nih.gov]

Celiac Disease with Diffuse Intestinal Ulceration

In addition, villous atrophy in general is associated with pancreatic insufficiency. [omicsonline.org]

atrophy, crypt hyperplasia, lamina propria lymphoplasmacytic infiltrate, intraepithelial lymphocytosis Monomorphic variant (type II EATL) : medium sized, round, dark nuclei [pathologyoutlines.com]

Severe villous atrophy is seen (A) without any increase in intraepithelial lymphocytes (B). [journals.plos.org]

Childhood Celiac Disease

By contrast, 96 (84%) of 114 children with other malabsorptive disorders and a normal mucosa or with partial villous atrophy had no gliadin antibodies, 14 (12%) had a low [ncbi.nlm.nih.gov]

Three children are described with long-standing pica and iron-deficiency anemia and in whom total villous atrophy consistent with celiac disease was found on jejunal biopsy [hero.epa.gov]

This is referred to as villous atrophy. [coeliac.org.au]

Chronic Diarrhea with Villous Atrophy

Villous Atrophy, is also known as chronic diarrhea with villous atrophy. [malacards.org]

An idiopathic, possibly immune-mediated, villous atrophy occurs in dogs. villous pertaining to or emanating from villi. villous atrophy reduction in size of the villi of the [medical-dictionary.thefreedictionary.com]

atrophy (slight, moderate, or severe), and subtotal villous atrophy (22). [acronymfinder.com]

Nodular Lymphoid Hyperplasia of the Intestine

[…] ectasia of colon Vascular ectasia of small intestine Villous atrophy of intestine Visceroptosis ICD-10-CM Diagnosis Codes General Equivalence Mappings (GEMS): ICD-10-CM Code [emedcodes.com]

[…] ectasia of colon Vascular ectasia of small intestine Villous atrophy of intestine Visceroptosis 569.89 Excludes Applies To Enteroptosis Granuloma of intestine Prolapse of [icd9data.com]

Partial villous atrophy was noted in 11 cases and it was well associated with the weight loss and low globulin levels than those without villous atrophy. [medresearch.in]

HIV-Associated Enteropathy

villous atrophy. [hindawi.com]

CONCLUSIONS: Villous atrophy in HIV enteropathy is attributed to crypt hypertrophy and encroachment of crypt cells onto villi. [ncbi.nlm.nih.gov]

atrophy occurs. [semanticscholar.org]

Alpha-Heavy Chain Disease

The small intestine revealed villous atrophy, diminished crypts, and intact surface epithelium. [ncbi.nlm.nih.gov]

There is extensive villous atrophy of the small intestinal mucosa, which is heavily infiltrated by small lymphocytes and plasma cells. [codes.iarc.fr]

Villous atrophy and plasma cell infiltration of the jejunal mucosa are usually present and, sometimes, infiltration of the mesenteric lymph nodes. [merckmanuals.com]

Tropical Sprue

OBJECTIVE: This study describes endoscopic findings associated with villous atrophy during EME. [ncbi.nlm.nih.gov]

In all patients, a distal duodenal biopsy showed partial villous atrophy. [ncbi.nlm.nih.gov]

The changes seen varied from mild to partial villous atrophy. Broad synechia and bridge formation between adjoining villi due to fusion was frequently observed. [ncbi.nlm.nih.gov]

Dermatitis Herpetiformis

At diagnosis, the majority of patients have villous atrophy in the small bowel mucosa. [ncbi.nlm.nih.gov]

Prominent gastrointestinal symptoms are rare, and small-bowel findings range from severe villous atrophy (SVA) and partial villous atrophy (PVA) to normal mucosa with inflammatory [ncbi.nlm.nih.gov]

Gastrointestinal symptoms and the degree of villous atrophy are less obvious in dermatitis herpetiformis than in coeliac disease. [ncbi.nlm.nih.gov]

Enteropathy-Associated T-Cell Lymphoma

Mucosal spreading and intraepithelial invasion by lymphoma with villous atrophy were detected adjacent to the mucosal layer. [ncbi.nlm.nih.gov]

The jejunum was involved by a multifocal large cell lymphoma associated with multiple inflammatory ulcers and villous atrophy with crypt hyperplasia of the intervening mucosa [ncbi.nlm.nih.gov]

atrophy, crypt hyperplasia, lamina propria lymphoplasmacytic infiltrate, intraepithelial lymphocytosis Monomorphic variant (type II EATL) : medium sized, round, dark nuclei [pathologyoutlines.com]

Intestinal Lymphoid Hyperplasia

[…] ectasia of colon Vascular ectasia of small intestine Villous atrophy of intestine Visceroptosis 569.89 Excludes Applies To Enteroptosis Granuloma of intestine Prolapse of [icd9data.com]

Partial villous atrophy was noted in 11 cases and it was well associated with the weight loss and low globulin levels than those without villous atrophy. [medresearch.in]

In small bowel mild villous blunting and atrophy without crypt hyperplasia was seen. The number of intraepithelial lymphocytes was within normal range. [ijpmonline.org]

Intestinal Lymphoma

Abstract Of 18 patients with small-intestinal lymphoma associated with villous atrophy and crypt hyperplasia of uninvolved mucosa, most presented with acute obstruction or [ncbi.nlm.nih.gov]

Pathologically, the following features are characteristic for Middle Eastern lymphoma: partial or total villous atrophy with only mildly abnormal surface epithelium, sparsity [ncbi.nlm.nih.gov]

Plasma postheparin DAO (PHD) values have been shown to be significantly lower in patients with malabsorption and villous atrophy, thus suggesting that PHD reflects the mature [ncbi.nlm.nih.gov]

Intestinal Strongyloidiasis

Because the larvae invade the lymph vessels, resulting in lymphangiectasia in edematous enteritis, the appearance of white villi may reflect villous atrophy/destruction and [ncbi.nlm.nih.gov]

Duodenal biopsy showed normal histology in twelve (80%) and partial villous atrophy in one (6.7%) patient. [ncbi.nlm.nih.gov]

Duodenal biopsy showed normal histology in twelve (80%), and partial villous atrophy in one (6.7%) patient. [tropicalgastro.com]

Disaccharidase Deficiency

Subjects classified as “abnormal” usually had varying amounts of villous atrophy or histological mucosal inflammation. [wjgnet.com]

atrophy (brush border excellently decorated by the IHC marker for CD10). [palpath.com]

The prevalence of villous atrophy ranged from 8.7% to 100%. Sixteen studies examined the association of histologic findings with disaccharide activities. [wjgnet.com]

Placenta Membranacea

atrophy during early gestation, and 30% of cases involve some form of placental adherence. [portal.europeana.eu]

Its incidence in humans is estimated to be between 1 in 20,000 to 40,000 pregnancies.[1] Because of failure of villous atrophy in early gestation, functional villi cover the [journals.lww.com]

[…] membranacea percreta Intrapartal resection of the bicornuete uterus for placenta membranacea percreta Placenta membranacea is a rare anomaly characterized by failure of villous [portal.europeana.eu]

Chronic Duodenitis

atrophy Type 3a: mild villous atrophy with V: C < 3:1, and ↑ IELs Type 3b: marked villous atrophy with V: C < 1:1, and ↑ IELs Type 3c: total villous atrophy with completely [wjgnet.com]

atrophy, more neutrophils but fewer plasma cells Gastric metaplasia, Helicobacter pylori may be present Microscopic (histologic) images Images hosted on other servers: Back [pathologyoutlines.com]

atrophy [ 7 ]. [omicsonline.org]

Heavy Chain Disease

Associated with massive infiltration of the lamina propria of the intestine and abdominal lymph nodes by lymphocytes, plasma cell and histiocytes causing villous atrophy and [gpnotebook.co.uk]

Investigations confirmed severe intestinal malab-sorption and a peroral jejunal biopsy showed villous atrophy with marked infiltration of the lamina propria by [jamanetwork.com]

Villous atrophy and plasma cell infiltration of the jejunal mucosa are usually present and, sometimes, infiltration of the mesenteric lymph nodes. [merckmanuals.com]

Eosinophilic Gastritis

Large number of eosinophils may also be present in the muscularis and serosal layer which may produce crypt hyperplasia, epithelial cell necrosis and villous atrophy. tags [medtube.net]

Eosinophilic infiltration may cause epithelial cell necrosis, pit or crypt abscesses, erosions, shallow ulcers, or villous atrophy. [flipper.diff.org]

[…] blunting and atrophy confirming the diagnosis of eosinophilic enteritis. [ncbi.nlm.nih.gov]

Intestinal Disease

The combination of villous atrophy and a predominantly plasma cell infiltration of the lamina propria in jejunal biopsy specimens may indicate lymphoma in adjacent bowel or [ncbi.nlm.nih.gov]

Abstract Chronic tubulointerstitial renal disease and villous atrophy of the small intestine occurred in two first cousins. [ncbi.nlm.nih.gov]

Villous atrophy can also occur with prolonged use of some medications. [scielo.mec.pt]

Cryptogenic Multifocal Ulcerous Stenosing Enteritis

atrophy and malabsorption excluded chronic ulcerative non-granulomatous jejunitis.2 Review of the small-bowel barium study confirmed unusual discrete strictures in the jejunum [ncbi.nlm.nih.gov]

In particular, there was no villous atrophy. A jejunoscopy was carried out in one patient and showed jejunal ulcerous strictures. [gut.bmj.com]

[…] ulceration were absent, making Crohn’s disease unlikely (at a histology meeting none of three pathologists thought the slides consistent with Crohn’s), whilst the absence of villous [ncbi.nlm.nih.gov]

Congenital Diarrhea

Duodenal mucosa with subtotal villous atrophy, without inflammation. Figure 2. CD 10 Immunostaining. [scielo.cl]

Syndrome of intractable diarrhea with persistent villous atrophy in early childhood: A clinicopathological survey of 47 cases. [scielo.cl]

Bruce-Winship Syndrome

Autoimmune enteropathy is primarily diagnosed in children presenting with intractable secretory diarrhea and villous atrophy. [emedicine.medscape.com]

Acrodermatitis enteropathica is an autosomal recessive disease with selective inability to absorb zinc, leading to villous atrophy and acral dermatitis. [emedicine.medscape.com]