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43 Possible Causes for Vortex Keratopathy

  • Fabry Disease

    Keratopathy may be the presenting feature in asymptomatic patients, and must be differentiated from other causes of vortex keratopathy (e.g. drug deposition in the cornea)[en.wikipedia.org] keratopathy), i.e. clouding of the corneas.[en.wikipedia.org] -like symptoms with neuropathy (in particular, burning extremity pain). [ citation needed ] Ocular involvement may be present showing cornea verticillata (also known as vortex[en.wikipedia.org]

  • Suramin

    Vortex keratopathy occurred in six patients given high-dose intravenous suramin for adrenocortical carcinoma. The corneal findings were bilateral and symmetric.[ncbi.nlm.nih.gov] Toxicity included proteinuria (14 patients), reversible liver function test abnormalities (eight), vortex keratopathy (five), adrenal insufficiency (three), coagulopathy secondary[ncbi.nlm.nih.gov]

  • Keratopathy

    Vortex keratopathy describes a unique presentation of corneal deposition in a classic arborizing or whorl-shaped pattern.[reviewdiseasehandbook.com] Vortex keratopathy is a common side effect of amiodarone.[nejm.org] Corneal manifestations include vortex keratopathy and decreased corneal sensation.[reviewofcontactlenses.com]

  • Optic Neuropathy

    The most common ocular adverse effect of amiodarone, found in almost all patients on long-term therapy, is a reversible verticillate keratopathy, also called vortex keratopathy[emedicine.medscape.com]

  • Heat Ray Cataract

    keratopathy, spoke-like cataract Steroid responders can form Glutathione - GSH does what to the lens change in intergrity of protein of lens contributing to color changes[quizlet.com] […] galactose utilization, "oil droplet" cataract AR, the first enzyme in metabolic pathway of galactose use, lamellar cataract X-linked, deficiency in alpha-galactosidase, vortex[quizlet.com]

  • Nitrofurantoin Toxicity

    Signs Ocular signs cornea – vortex keratopathy - consists of grayish or golden brown corneal epithelial deposits.[eyewiki.aao.org] Symptoms – decreased VA & color vision Ocular signs – Anterior segment - vortex keratopathy Fundus – bilateral multiple, yellow, crystalline, ring like deposits in the maculae[eyewiki.aao.org]

  • Sclerosing Keratitis

    keratopathy, cataract ( usually of no visual consequence) and bull eye maculopathy.[mrcophth.com] […] keratolysis sclerosing keratitis acute stromal keratitis peripheral guttering drug-induced steroid causing glaucoma and posterior subcapsular cataract hydroxychloroquine causing vortex[mrcophth.com]

  • Amiodarone

    Vortex keratopathy is a common side effect of amiodarone.[nejm.org] To report a case of amiodarone-induced vortex keratopathy-associated anatomical findings and subjective visual perception before and after treatment with topical heparin eye[ncbi.nlm.nih.gov] […] or whorl keratopathy) are almost universally present (over 90%) in individuals taking amiodarone longer than 6 months, especially doses greater than 400 mg/day.[en.wikipedia.org]

  • Arcus Juvenilis

    The most common ocular finding in Fabry disease is cornea verticillata, also known as vortex keratopathy .[consultant360.com]

  • Heparin

    To report a case of amiodarone-induced vortex keratopathy-associated anatomical findings and subjective visual perception before and after treatment with topical heparin eye[ncbi.nlm.nih.gov]

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