Possible Causes for Walking Delay Congenital Merosin-Positive Muscular Dystrophy Some children will walk, but sometimes this can be delayed until the age of five or older. → Leg splints are often used to assist a child to walk. [mobilephysiotherapyclinic.in] Delayed ability to roll over Delayed ability to stand with support Delayed ability to sit alone Delayed ability to walk alone (nearly half walk after 4 years) Mild facial [checkorphan.org] […] inward) thumbs. [2] a rare form of CMD causing permanent shortening of the toe joints and lack of muscle tone which can delay walking due to the individual being weak. [ipfs.io] Duchenne Muscular Dystrophy Early signs include delay in walking, frequent falling, and difficulty getting up from a sitting or lying position. [web.archive.org] Physical Exam Symptoms progressive weakness affecting proximal muscles first (begins with gluteal muscle weakness) gait abnormalities delayed walking toe walking clumsy, waddling [orthobullets.com] Muscle weakness typically affects the hips, pelvic area, and thighs first, usually causing difficulty with standing and walking. [pfizer.com] Autosomal Recessive Spastic Paraplegia Type 18 They all presented in the first 2 years of life with developmental delay, delayed walking, abnormal gait, and mild to severe mental retardation. [cags.org.ae] […] motor development Delayed motor skills 0002194 Difficulty walking Difficulty in walking 0002355 Elbow flexion contracture Contractures of elbows Elbow contracture Elbow contractures [rarediseases.info.nih.gov] If they learn to walk they tend to lose it during adolescence (occasionally adulthood). [patient.info] Congenital Neuropathy with Arthrogryposis Multiplex […] lower limbs areflexia, lower limbs no sensory defects Skeletal Limbs: limited joint flexion Neurologic Central Nervous System: wide-based gait extensor plantar responses delayed [malacards.org] 0002136 Calcaneovalgus deformity 0001848 Congenital onset Symptoms present at birth 0003577 Congenital peripheral neuropathy 0006903 Delayed ability to walk 0031936 Distal [rarediseases.info.nih.gov] Ambulation: Walking is often delayed until to 2-5 years old. 3. Scoliosis: Can be rapidly progressive if detected before 1 year of age. 4. [now.aapmr.org] Joubert Syndrome Type 3 […] the eyes and thus require regular monitoring. [4] Prognosis [ edit ] In a sample of 19 children, a 1997 study found that 3 died before the age of 3, and 2 never learned to walk [en.wikipedia.org] The children had various levels of delayed development with developmental quotients from 60 to 85. [11] Research [ edit ] Research has revealed that a number of genetic disorders [en.wikipedia.org] Charcot-Marie-Tooth Disease Type 2R Definición: A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition[…] [hon.ch] Baker-Gordon Syndrome Walking and speech are delayed and moderate to profound intellectual impairment is virtually always present. [disorders.eyes.arizona.edu] The patients, who ranged from 3 to 21 years of age, had global developmental delay from infancy, including hypotonia and delayed walking or inability to walk (7 patients), [findzebra.com] There is general developmental delay with impaired intellectual development, delayed or absent walking, and behavioral psychiatric manifestations such as stereotypic and unpredictable [disorders.eyes.arizona.edu] MED13L Haploinsufficiency Syndrome […] independently (delayed motor skills). [rarediseases.org] Weak muscle tone (hypotonia) and delayed development of motor skills, such as sitting, standing, and walking, are early symptoms of the condition. [medlineplus.gov] At the last evaluation, the girl was 4 years and 5 months old, and she could not yet sit or stand without support, let alone walk. [ijponline.biomedcentral.com] X-Linked Mental Retardation Type Lubs […] ability to roll over Delayed ability to sit Delayed ability to walk Depression Developmental regression Generalized non-motor (absence) seizure Global developmental delay [ncbi.nlm.nih.gov] Hostility Inability to walk Intellectual disability, severe Lower limb spasticity Motor stereotypy Pain insensitivity Poor eye contact Progressive spasticity Repetitive compulsive [ncbi.nlm.nih.gov] […] behavior Seizure Severe global developmental delay Sleep disturbance Status epilepticus Tonic seizure Abnormality of the respiratory system Recurrent respiratory infections [ncbi.nlm.nih.gov] Ehlers-Danlos Syndrom Classic Type 1 Symptoms Symptoms of the syndrome are usually identified during childhood and may include any of the following: Delayed walking accompanied by joint hypermobility (highly [fdna.health] PHIP-Related Disorder Young children often have feeding difficulties and delayed developmental milestones like rolling, crawling, standing straight and walking. [chungjansensyndrome.eu] Delayed motor development is partly related to the low muscle tone (hypotonia). [chungjansensyndrome.eu] X-linked Mental Retardation Type Cabezas Speech and language difficulties Speech delay [ more ] 0000750 Distal lower limb amyotrophy 0008944 Gait ataxia Inability to coordinate movements when walking 0002066 Gynecomastia [rarediseases.info.nih.gov] Enlarged male breast 0000771 Motor delay 0001270 Pes planus Flat feet Flat foot [ more ] 0001763 Percent of people who have these symptoms is not available through HPO Abnormality [rarediseases.info.nih.gov] […] development Impaired speech development Language delay Language delayed Language development deficit Late-onset speech development Poor language development Speech and language delay [rarediseases.info.nih.gov] NKX2-1-Related Disorders The mutations were not detected in parents, despite the known history of walking delay in the paternal line. [ijponline.biomedcentral.com] The family history reported two cases of walking delay in the paternal line and several cases of autoimmune thyroid diseases in the maternal line. [ijponline.biomedcentral.com] […] independent walking. [ijponline.biomedcentral.com] Yuan-Harel-Lupski Syndrome Most patients had feeding difficulties, hypotonia, and failure to thrive in infancy, and all had global developmental delay with delayed walking, speech delay, and behavioral [findzebra.com] Delayed ability to walk MedGen UID: 66034 •Concept ID: C0241726 • Finding A failure to achieve the ability to walk at an appropriate developmental stage. [ncbi.nlm.nih.gov] Babies and children with YUHAL syndrome have delayed development, including delayed speech and language skills and motor skills such as walking. [encyclopedia.pub] Shashi-Pena Syndrome The early hypotonia can evolve into subsequent delays in gross motor skills that manifest as delayed walking. [rarediseases.org] There is also a delay in speech and behavioral problems that can include attention deficit and autistic features. [rarediseases.org] Lissencephaly Type 8 Delayed ability to walk MedGen UID: 66034 •Concept ID: C0241726 • Finding A failure to achieve the ability to walk at an appropriate developmental stage. [ncbi.nlm.nih.gov] […] ability to walk Delayed fine motor development Delayed gross motor development Delayed social development Delayed speech and language development Global developmental delay [ncbi.nlm.nih.gov] […] muscles of the body for walking, running, sitting, and crawling. [ncbi.nlm.nih.gov] Usher Syndrome Type 1E walking (>18 months); and the onset of RP by the age of ten (Keats and Lentz, 2006). [usher-syndrome.org] Babies may show delays in sitting and walking, and experience disorientation throughout their life, particularly as their sight changes. [sense.org.uk] […] syndrome type I is the most severe form of Usher syndrome and is characterized by congenital, profound, sensorineural hearing loss; vestibular dysfunction, often manifested as delayed [usher-syndrome.org] Snijders Blok-Campeau Syndrome Delayed ability to walk MedGen UID: 66034 •Concept ID: C0241726 • Finding A failure to achieve the ability to walk at an appropriate developmental stage. [ncbi.nlm.nih.gov] Many children have feeding difficulties, and sitting, standing, and walking are often delayed. Quick Facts [chd3.org] She also had hypotonia and was not able to stand or walk independently. She can say "ma ma" unconsciously. [x-mol.com] Galloway-Mowat Syndrome Type 6 […] skeletal maturation Microcephaly Abnormality of the nervous system Cerebellar atrophy Cerebellar vermis atrophy Delayed ability to walk Delayed speech and language development [ncbi.nlm.nih.gov] Delayed ability to walk MedGen UID: 66034 •Concept ID: C0241726 • Finding A failure to achieve the ability to walk at an appropriate developmental stage. [ncbi.nlm.nih.gov] and other developmental milestones) and a profound delay in the attainment of skills requiring the coordination of muscular and mental activity (psychomotor retardation) [rarediseases.org] Ververi-Brady Syndrome The third patient was a 13-year-old Chinese girl who showed delayed walking and delayed speech acquisition in early childhood, but was able to attend a mainstream school with [findzebra.com] Unsteady gait MedGen UID: 68544 •Concept ID: C0231686 • Finding A shaky or wobbly manner of walking. [ncbi.nlm.nih.gov] She also has Ververi-Brady Syndrome, which causes developmental delay Florence Swaffield has child dementia A girl aged three is losing the ability to walk because of the [mirror.co.uk] Chromosome 22q13.3 Deletion Syndrome Development Developmental delays, such as delayed sitting up, rolling over, walking or talking Delayed or absent speech Autism spectrum disorder (ASD, or a condition that [massgeneral.org] Children also experience a significant delay in reaching early developmental milestones, such as rolling over, sitting, crawling and walking; this delay is likely associated [rarediseases.org] Symptoms your child may have include: Developmental delay (not hitting milestones at expected times, such as rolling over, sitting up or walking). High pain tolerance. [my.clevelandclinic.org] Jaberi-Elahi Syndrome All had delayed psychomotor development with mildly delayed walking, delayed speech, intellectual disability (IQ of 40 to 50), and behavioral abnormalities. [findzebra.com] Globus pallidus hypointensity on susceptibility-weighted imaging Hypoplasia of the corpus callosum Inability to walk Intellectual disability Motor delay Severe global developmental [ncbi.nlm.nih.gov] Broad-based gait MedGen UID: 167799 •Concept ID: C0856863 • Finding An abnormal gait pattern in which persons stand and walk with their feet spaced widely apart. [ncbi.nlm.nih.gov] Autosomal Dominant Mental Retardation Type 1 Symptoms may include seizures, moderate to severe learning problems, speech delays, behavior problems, trouble sleeping, and developmental delays (learn to crawl, sit or walk [rarediseases.org] Gillespie Syndrome This abnormality can cause delayed development of motor skills such as walking. [rarediseases.oscar.ncsu.edu] This abnormality can cause hypotonia and delayed development of motor skills such as walking. [medlineplus.gov] She started walking unaided by 9 years with a significantly unsteady gait and her speech was similarly delayed. Physical examination revealed multiple cerebellar signs. [bmcpediatr.biomedcentral.com] Distal Trisomy 2p He was noted to have gross motor delay with hypotonia and walked at 22 months. Speech development was severely delayed necessitating Makaton from the age of 2 years. [jmg.bmj.com] Mitochondrial DNA-Related Leigh Syndrome and NARP […] in attaining development milestones such as sitting up, crawling, or walking (developmental delays). [rarediseases.org] Common symptoms associated with NARP syndrome include an impaired ability to coordinate voluntary movements (ataxia), migraines, seizures, learning disabilities, and delays [rarediseases.org] Charcot-Marie-Tooth Disease Type 2E Children often present within the first two years of life with delayed walking. [cmtausa.org] Symptoms affect both lower and upper limbs, including muscle wasting and contractures, and delayed milestones such as sitting and walking. [cmtausa.org] About 40 percent of people with CMT1B have an infantile onset with delayed walking (after 15 months), and development of symptoms before 5 years of age. [cmtausa.org] Muscular Dystrophy (delayed walking) Intellectual disability is present in some types of muscular dystrophy. [nlm.nih.gov] […] using one or more muscle groups Drooling Eyelid drooping (ptosis) Frequent falls Loss of strength in a muscle or group of muscles as an adult Loss in muscle size Problems walking [medlineplus.gov] […] balance Decrease in muscle size Difficulty walking or delay in starting to walk How Is Muscular Dystrophy Diagnosed? [nationwidechildrens.org] Infantile Hypotonia with Psychomotor Retardation - Characteristic Facies Type 2 The main symptoms of the syndrome include delayed development, limited speech development, and usually an inability to walk unaided. [fdna.health] The main symptoms of the syndrome are delayed global development, limited to zero speech development, and limited ability to walk. [fdna.health] Infantile, with Psychomotor Retardation and Characteristic Facies 3; IHPRF3 was created to help geneticists get a better analysis This rare disease is a neurodevelopmental delay [fdna.health] SOX2-Related Eye Disorders Individuals with SOX2 anophthalmia syndrome may also have seizures, brain abnormalities, slow growth, delayed development of motor skills (such as walking), and mild to severe [medlineplus.gov]
