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146 Possible Causes for Weakness of the Intrinsic Hand Muscles

  • Monomelic Amyotrophy

    O'Sullivan-McLeod syndrome (see this term), considered to be a variant of MA, presents with weakness in the intrinsic hand muscles.[] […] the intrinsic hand muscles (interossei, thenar, and hypothenar muscle groups) as well as the ulnar side of the forearm.1,3 There is sparing of brachioradialis muscle giving[] ), and the patient had severe weakness of the intrinsic musculature of the hand (0/5).[]

  • Malathion Poisoning

    OPIDN associated signs include foot drop, weakness of the intrinsic hand muscles, absent ankle jerks and weakness of hip and knee flexors.[] The late manifestation which occurred in our patient was sub acutely developed weakness of lower and upper extremity which was diagnosed to be Organophosphate Induced Delayed[]

  • Holt Oram Syndrome

    Physical exam showed bilateral atrophic upper extremities with anatomic disfiguration, and weakness of the intrinsic hand muscles.[]

  • Brown-Vialetto-Van Laere Syndrome

    […] of her intrinsic hand muscles.[] Her motor functions steadily improved over 5 weeks such that at discharge she could walk short distances unaided with ankle–foot orthoses for bilateral foot drop and mild weakness[]

  • Upper Motor Neuron Disease

    O'Sullivan-McLeod syndrome (see this term), considered to be a variant of MA, presents with weakness in the intrinsic hand muscles.[] Patients may also notice a change in the appearance of their hands (due to wasting of the intrinsic muscles).[] Additional rare manifestations include worsening of symptoms with exposure to cold (cold paresis), muscle cramps, cold hands, irregular coarse tremor and/or contraction fasciculations[]

  • Cervical Spondylosis

    We found 19 patients with weakness and atrophy of the intrinsic hand muscles, and 13 patients with weakness proximal to the hand muscles to serve as a control group.[] The main clinical features are localized wasting and weakness of the extrinsic and intrinsic hand muscles, but not accompanied by either sensory loss or spastic quadriparesis[] The clinical and radiological findings were compared to a control group of patients with weakness of the arm or forearm muscles and similar mid-cervical spondylosis.[]

  • Thoracic Outlet Syndrome

    True NTOS manifests slowly with the progressive unilateral atrophic weakness of the intrinsic hand muscles and sensory abnormalities in a T1 distribution due to a lower trunk[] Symptoms related to neurogenic TOS include intrinsic hand muscle and thenar region atrophy and weakness, as well as medial hand and forearm numbness, which are all suggestive[] There was weakness (grade 3-4 on MRC scale) of thenar, hypothenar and intrinsic muscles of the left hand.[]

  • Pronator Syndrome

    […] in the intrinsic muscles of the hand and muscles of the forearm, but usually the weakness is not severe compared to compression at the level of the anterior interosseous[] Distinctive findings are weakness of both the intrinsic muscles of the hand supplied by the median nerve and the muscles proximal to the wrist and in the forearm with tenderness[] […] cases which were effectively treated by Leahy's method of "active release" as described in articles by Leahy and Mock. 4,5 In severe cases of pronator syndrome there may be weakness[]

  • Spondyloepiphyseal Dysplasia Type Byers

    weakness Distal lower limb amyotrophy Axial muscle weakness Limb joint contracture Toe walking Weakness of the intrinsic hand muscles Abnormality of the Achilles tendon Progressive[] […] tall stature Degeneration of anterior horn cells Brisk reflexes Overlapping toe Hip contracture Axonal loss Difficulty running Achilles tendon contracture Shoulder girdle muscle[]

  • Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1H

    […] tremor Distal lower limb amyotrophy Hyperlipoproteinemia Kinetic tremor Acanthocytosis Obsessive-compulsive behavior Gait disturbance Weakness of the intrinsic hand muscles[] […] disorder characterized by onset in young adulthood of distal muscle weakness affecting the upper and lower limbs but sparing the intrinsic hand muscles.[] Retinal degeneration Pigmentary retinopathy Mask-like facies Neck muscle weakness Progressive ptosis Pes cavus Dyspnea Ranula Spinal canal stenosis Loss of ability to walk[]

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