Possible Causes for wheelchair bound Duchenne Muscular Dystrophy Children suffering from this disease eventually become wheelchair bound and die in their late teens. [ncbi.nlm.nih.gov] Patients become wheelchair bound and develop respiratory muscle weakness. [stanfordhealthcare.org] Progressive muscle weakness often causes Duchenne patients to become wheelchair bound before the age of 12. [biomarin.com] Becker Muscular Dystrophy Two patients became wheelchair bound in their 40s or beyond, while the other 2 (aged 73 and 69, respectively) were still able to walk at the time of examination. [ncbi.nlm.nih.gov] The early clinical course in BMD is milder than that in DMD, and patients become wheelchair-bound at age sixteen or older. [clinicaladvisor.com] However, following the honeymoon period, clinical deterioration is noted, and the patient is usually wheelchair-bound by age thirteen. [clinicaladvisor.com] Paraplegia Patients with progressive HSP are often wheelchair-bound by the age of 70 years. Patients with HSP have a normal life-expectancy. [amboss.com] ‘For example, a person with paraplegia who is wheelchair-bound may be working successfully on a full-time basis as an accountant and therefore not meet the Social Security [lexico.com] […] a man with paraplegia who had multiple Stage IV ulcers and flap repairs in the past, verbalized his feelings about stereotypical terms used in relationship to people in wheelchairs [lexico.com] Quadriplegia It isn't the way the able-bodied and the wheelchair-bound normally interact. "Sometimes I won't even notice what's being done," he says of his morning manoeuvres. [theguardian.com] Spiral-bound format enables the book to lay flat for easy reference in the clinical setting or classroom. [elsevier.com] Excellent coverage of wheelchairs and wheelchair management is included. Table of Contents Spinal Cord Injury 2. Physiological Effects and Their Initial Management 3. [elsevier.com] Fibrodysplasia Ossificans Progressiva bound by the age of 30. [ncbi.nlm.nih.gov] This leads to progressive immobility; patients are usually wheelchair-bound by the second decade of life and die of thoracic insufficiency by the fourth decade of life. [ncbi.nlm.nih.gov] Most patients are wheelchair-bound by the end of the second decade of life and commonly die of complications of thoracic insufficiency syndrome. [ncbi.nlm.nih.gov] Unverricht-Lundborg Syndrome After a mean duration of disease of 29.9 years (range: 21-37 years), four patients were walking with aids while another four were wheelchair bound. [hanyang.elsevierpure.com] An estimated one-third of the patients eventually become wheelchair-bound. This study is a part of Finnish EPM1 clinical and molecular genetics consortium research. [uef.fi] bound. [karger.com] Muscular Dystrophy Case 2 became wheelchair-bound at the age of 60. No cognitive or behavioral symptoms were noted. [ncbi.nlm.nih.gov] A small percentage of people become wheelchair-bound. Hearing loss and abnormal heart rhythms may occur, but are rare. [web.archive.org] Patients become wheelchair bound and develop respiratory muscle weakness. [stanfordhealthcare.org] Limb-Girdle Muscular Dystrophy Type 2B The age at the onset of disease ranged from 9 yr to 33 yr, and none of the patients was wheelchair bound at the neurological examination. [ncbi.nlm.nih.gov] Patients are usually wheelchair-bound about 25 years after diagnosis, and life expectancy may be shorter than a natural life-span. [sema4genomics.com] bound LGMD2H 8–27 years Wheelchair bound LGMD2I 1.5–27 years Wheelchair bound LGMD1A 18–35 years Proximal leg and arm weakness Distal weakness Tight Achilles tendon Problems [encyclopedia.com] Limb-Girdle Muscular Dystrophy Type 2C Progression is rapid, and patients are usually wheelchair-bound in adolescence. [sema4genomics.com] Most individuals affected with limb-girdle muscular dystrophy type 2C (LGMD2C) start symptoms in early childhood and are wheelchair bound by about 12 years of age. [geneaware.clinical.bcm.edu] bound LGMD2H 8–27 years Wheelchair bound LGMD2I 1.5–27 years Wheelchair bound LGMD1A 18–35 years Proximal leg and arm weakness Distal weakness Tight Achilles tendon Problems [encyclopedia.com] Early-Onset Cerebellar Ataxia The latency until becoming wheelchair-bound, however, was significantly longer in EOCA than in FA. The segregation ratio in EOCA was significantly lower than 0.25. [ncbi.nlm.nih.gov] Prognosis The period of latency before becoming wheelchair-bound is significantly longer in EOCARR than in FRDA, resulting in a better prognosis in patients with EOCARR than [orpha.net] Annual progression rate and the percentage of patients who were wheelchair-bound was lower in EOCA as compared with FA, although the difference did not reach statistical significance [ncbi.nlm.nih.gov] Limb-Girdle Muscular Dystrophy Case 2 became wheelchair-bound at the age of 60. No cognitive or behavioral symptoms were noted. [ncbi.nlm.nih.gov] The age at the onset of disease ranged from 9 yr to 33 yr, and none of the patients was wheelchair bound at the neurological examination. [ncbi.nlm.nih.gov] She was wheelchair-bound by age 12. [ncbi.nlm.nih.gov] Congenital Hypothyroidism without Goiter Many people with Allan–Herndon–Dudley syndrome are unable to walk independently and become wheelchair-bound by adulthood. [en.wikipedia.org] As a result, many people with Allan-Herndon-Dudley syndrome are unable to walk independently and become wheelchair-bound by adulthood. [hellodoktor.com] Autosomal Recessive Spinocerebellar Ataxia Joint contractures sometimes develop and patients can be wheelchair-bound by the second decade. Dysarthric speech is common. No dysmorphic facial features are present. [disorders.eyes.arizona.edu] Gradually, patients usually develop a slurred speech with distal amyotrophy and are wheelchair-bounded by 40 year-old. [radiopaedia.org] bound. [centogene.com] CANOMAD Syndrome Significant disability is the rule, with only 3 of 18 able to walk unaided, and 5 of 18 wheelchair bound. [reliasmedia.com] All 11 patients had sensory ataxia and gait disorders ranged from mild (ambulating independently) to severe (wheelchair bound). [neurology.org] Muscular Dystrophy-Dystroglycanopathy Type C14 bound LGMD2H 8–27 years Wheelchair bound LGMD2I 1.5–27 years Wheelchair bound LGMD1A 18–35 years Proximal leg and arm weakness Distal weakness Tight Achilles tendon Problems [encyclopedia.com] Progression is rapid, and patients are usually wheelchair-bound in adolescence. [sema4genomics.com] Patients can become wheelchair bound in their early teens and die from respiratory complications in their late teens. [emedicine.medscape.com] Limb-Girdle Muscular Dystrophy Type 2Q bound LGMD2H 8–27 years Wheelchair bound LGMD2I 1.5–27 years Wheelchair bound LGMD1A 18–35 years Proximal leg and arm weakness Distal weakness Tight Achilles tendon Problems [encyclopedia.com] Patients are usually wheelchair-bound about 25 years after diagnosis, and life expectancy may be shorter than a natural life-span. [sema4genomics.com] Most individuals affected with limb-girdle muscular dystrophy type 2A (LGMD2A) start showing signs of muscle weakness in childhood and are wheelchair bound in 11-28 years [geneaware.clinical.bcm.edu] Autosomal Recessive Spastic Paraplegia Type 35 It has a rapid progression and many patients become wheelchair-bound as young adults. Patients manifest cognitive decline associated with leukodystrophy. [uniprot.org] He walked with a stick from the age of 25 years and became wheelchair bound aged 39. [journals.plos.org] She became wheelchair bound from the age of 43 years. Examination at the age of 63 years showed severe cerebellar ataxia in truncus and extremities. [journals.plos.org] Infantile-Onset Ascending Hereditary Spastic Paralysis bound by late childhood or early adolescence Treatment - Hereditary spastic paralysis- infantile onset ascending Not supplied. [checkorphan.org] All the patients were wheelchair-bound by the age of 10 years. In the second decade, the disease progressed to tetraplegia, anarthria, dysphagia, and slow eye movements. [ncbi.nlm.nih.gov] At examination 35 patients used a walking aid, 15 patients were wheelchair-bound. [ojrd.biomedcentral.com] Autosomal Recessive Spastic Paraplegia Type 27 They had become wheelchair bound after 2–18 years of gait impairment. [nature.com] He walked with a stick from the age of 25 years and became wheelchair bound aged 39. [journals.plos.org] bound after 1 or 2 decades of the disease. [demneuropsy.com.br] Viral Upper Respiratory Tract Infection Most patients in the infection group had severe muscle weakness and were either wheelchair- or bed-bound. [atsjournals.org] 7 Myotonic dystrophy 11 F Walks 8 Myotonic dystrophy 8 M Walks 9 Duchenne's disease 13 M Wheelchair 10 Werdnig-Hoffman disease 29 M Bed-bound Table 2. [atsjournals.org] CLINICAL FEATURES OF NEUROMUSCULAR PATIENTS WITHOUT URI Case Disease Type Age Sex Functional Status* 1 Spinal muscular atrophy 38 M Wheelchair 2 Limb-girdle dystrophy 22 [atsjournals.org] Limb-Girdle Muscular Dystrophy Type 2A Most individuals affected with limb-girdle muscular dystrophy type 2A (LGMD2A) start showing signs of muscle weakness in childhood and are wheelchair bound in 11-28 years [geneaware.clinical.bcm.edu] Patients are usually wheelchair-bound about 20 years after diagnosis, and death usually occurs in middle age. [sema4genomics.com] A patient typically becomes wheelchair bound 20 - 30 years after disease onset. [impact.ref.ac.uk] Autosomal Dominant Spastic Paraplegia Type 8 The disorder has an adult-onset and some affected individuals become wheelchair-bound as the disease progresses. [cags.org.ae] Some patients may become wheelchair-bound after several decades. [diseaseinfosearch.org] Disease severity was highly variable both within and among families: we observed asymptomatic mutation carriers 70 years old as well as severely affected patients who were wheelchair-bound [academic.oup.com] Constipation […] fibre versus another type of diet or fibre One crossover study ( Dahl 2005 ) compared an inulin‐fortified beverage with a standard modified starch‐thickened beverage in wheelchair‐bound [dx.doi.org] bound institutionalised adults with MS (7), cerebral palsy (4), SCI (2) and brain injury (2) ( Dahl 2005 ). [dx.doi.org] Oral laxatives Three trials evaluated oral laxatives, two in individuals with Parkinson's disease ( Ashraf 1997 ; Zangaglia 2007 ) and one in a mixed sample including 15 wheelchair [dx.doi.org] Progressive Myoclonic Epilepsy Type 8 […] myoclonus Mild action myoclonus Moderate action myoclonus Ataxia Not described Not described Not described Not described Truncal and appendicular ataxia Gait impairement Wheelchair‐bound [onlinelibrary.wiley.com] Hypomyelinating Leukodystrophy Type 5 Most patients become wheelchair-bound late in the first decade of life and some do not survive beyond childhood. [disorders.eyes.arizona.edu] Most individuals become wheelchair bound between ages eight and nine years [ Biancheri et al 2007 ]. Cognitive skills. [ncbi.nlm.nih.gov] The patients showed no severe clinical worsening, but most of them gradually lost their ability to walk, becoming wheelchair-bound. [ajnr.org] Oculomotor Apraxia He was wheelchair bound by the age of 23-years. [cags.org.ae] Prognosis AOA1 is a progressive neurodegenerative disorder and most patients usually become wheelchair bound from seven to ten years after onset of the disease. [orpha.net] Patients may hence become wheelchair-bound by the third or fourth decade of life. AOA3 has so far been diagnosed in only a single Saudi Arab family. [cags.org.ae] Diomedi-Bernardi-Placidi Syndrome Patients with progressive HSP are often wheelchair-bound by the age of 70 years. Patients with HSP have a normal life-expectancy. [amboss.com] Many become wheelchair-bound before their teens. Others can walk with a waddling gait. [childrenshospital.org] Friedreich Ataxia Trinucleotide expansion length was determined and lymphocyte frataxin levels measured. p.R165P mutation carriers became wheelchair bound early, but had retained reflexes, [ncbi.nlm.nih.gov] […] that treatment with idebenone might ameliorate hypertrophic cardiomyopathy; a well-designed phase II trial suggested concentration-dependent functional improvements in non-wheelchair-bound [ncbi.nlm.nih.gov] One patient is wheelchair-bound but the other two are able to walk with support. Leaving OD aside, skeletal anomalies are not prominent. [ncbi.nlm.nih.gov] Facioscapulohumeral Muscular Dystrophy However, the clinical spectrum of facioscapulohumeral muscular dystrophy (FSHD) ranges from asymptomatic individuals with minimal clinical signs to patients who are wheelchair-bound [ncbi.nlm.nih.gov] Symmetrical limb muscle weakness appeared at 15 years of age, which progressed such that she was wheelchair-bound at 18 years of age. [ncbi.nlm.nih.gov] From the age of 10 years, weakness of the lower limbs progressed and she became wheelchair-bound at the age of 14 years and 8 months. [ncbi.nlm.nih.gov] Autosomal Recessive Limb-Girdle Muscular Dystrophy bound LGMD2H 8–27 years Wheelchair bound LGMD2I 1.5–27 years Wheelchair bound LGMD1A 18–35 years Proximal leg and arm weakness Distal weakness Tight Achilles tendon Problems [encyclopedia.com] Most individuals affected with limb-girdle muscular dystrophy type 2D (LGMD2D) start showing signs of muscle weakness in early childhood and are wheelchair bound in about [geneaware.clinical.bcm.edu] She was never wheelchair bound and had no cranio-bulbar symptoms. [aeronline.org]
