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1,699 Possible Causes for White Matter Lesions

  • Late-onset Depression

    The prevalence of larger subcortical white matter lesions was higher in patients with LOD compared with patients with EOD (47% vs 8%; p 0.002).[] BACKGROUND: Cerebral white matter lesions (WMLs) are more common in individuals with late-onset or late-life depression.[] Some white matter lesions may be vascular in origin.[]

  • Susac Syndrome

    Results: All 27 patients had multifocal supratentorial white matter lesions including the corpus callosum.[] When symptoms recurred, magnetic resonance imaging showed new scattered gray and white matter lesions, many within the corpus callosum.[] Conclusions: The MR scans in SS show a rather distinctive pattern of supratentorial white matter lesions that always involve the corpus callosum.[]

  • Urea Cycle Disorder

    Histopathologically, cortical atrophy, basal ganglia lesions and white matter damage may be observed.[] Symmetric cystic lesions at the gray matter-white matter junction, especially in the sulcal depth of the frontal, parietal, hippocampal, and insular regions, are known early[] […] pathologic lesions resulting from hyperammonemic encephalopathy ( 13 , 14 ).[]

  • Subacute Sclerosing Panencephalitis

    CT or MRI may show cortical atrophy or white matter lesions.[] MRI can reveal multifocal white-matter lesions. Treatment The course of SSPE is variable, but it can last for years. There is no definitive treatment.[]

  • Primary Progressive Multiple Sclerosis

    matter lesions[] Additional diffusion-weighted imaging revealed restricted diffusion in the white matter lesions with a reduced apparent diffusion coefficient.[] Lesion load was negatively correlated with cortical and subcortical grey matter volumes, but not with total white matter volume.[]

  • Binswanger Disease

    Abstract OBJECTIVE: To identify the prevalence of MRI features of Binswanger's disease (BD), specifically MRI with diffuse white matter lesions and scattered multiple lacunes[] The white matter lesions are usually small, commonly grouped around the frontal and occipital horns and in the centrum semiovale.[] […] in the genesis of deep white matter lesions.[]

  • Progressive Multifocal Leukoencephalopathy

    matter lesions on brain magnetic resonance imaging (MRI).[] OBJECTIVE: To analyze SWI hypointensities recently described in U-fibers and cortex adjacent to the white matter lesions of PML.[] All three cases demonstrated the hyper-uptake of MET around the white matter lesions and hypo-uptake of FDG inside the lesions.[]

  • Acute Disseminated Encephalomyelitis

    We found a discrepancy between the lesion size and the clinical deficits of the patient, actually the clinical improvement antedated the regression of the white matter lesions[] Acute disseminated encephalomyelitis was confirmed by brain MRI which showed newly developed diffuse white matter lesions.[] His clinical course was fluctuating and repeat imaging one week after presentation demonstrated interval development of characteristic white matter lesions.[]

  • CADASIL Syndrome

    matter lesions are also seen in asymptomatic individuals with the mutated gene. [8] While MRI is not used to diagnose CADASIL, it can show the progression of white matter[] matter lesions subcortical infarcts in white matter, basal ganglia, and brain stem external capsules and temporal lobes are often affected Leukoencephalopathy is often present[] Other symptoms include white matter lesions throughout the brain, cognitive deterioration, seizures, vision problems, and psychiatric problems such as severe depression and[]

  • Optic Neuritis

    Axial, fluid-attenuated inversion recovery (FLAIR) image demonstrates bilateral periventricular white matter lesions.[] While AZOOR previously has been linked to MS and demyelinating white matter lesions in the brain, our case seems unique due to concurrent development of AZOOR and retrobulbar[] Eleven of the 29 patients (38%) had white matter T2/FLAIR (fluid-attenuated inversion recovery) lesions in the brain (not including the optic nerves).[]

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