White Matter Lesions Causes & Reasons

Neu starten

Ad Html Headline Ad Text Headline

Ad Label Ad Html Description Ad Text Description

Determine your risk of now. Restart test

Caution! In case of an emergency:

Seek emergency care

Caution! In case of an emergency: Seek emergency care

Hi, I'm Symptoma.

White Matter Lesions Symptom Checker: Possible causes include Late-onset Depression. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

For full functionality of this site it is necessary to enable JavaScript.

How to enable JavaScript?

Possible Causes

Late-onset Depression

The prevalence of larger subcortical white matter lesions was higher in patients with LOD compared with patients with EOD (47% vs 8%; p 0.002). [ncbi.nlm.nih.gov]

BACKGROUND: Cerebral white matter lesions (WMLs) are more common in individuals with late-onset or late-life depression. [ncbi.nlm.nih.gov]

Some white matter lesions may be vascular in origin. [ncbi.nlm.nih.gov]

Show info

Acute Intermittent Porphyria

Magnetic resonance (MR) imaging demonstrated multiple large contrast-enhancing subcortical white matter lesions, which regressed with glucose and hematin infusions. [ncbi.nlm.nih.gov]

Brain magnetic resonance imaging white-matter lesions and cerebrospinal fluid findings in patients with acute intermittent porphyria. [ncbi.nlm.nih.gov]

MRI studies in one showed white matter abnormalities that suggested selective postnatal involvement of cerebral oligodendrocytes [ Solis et al 2004 ]. [ncbi.nlm.nih.gov]

Show info

Susac Syndrome

Results: All 27 patients had multifocal supratentorial white matter lesions including the corpus callosum. [n.neurology.org]

When symptoms recurred, magnetic resonance imaging showed new scattered gray and white matter lesions, many within the corpus callosum. [ncbi.nlm.nih.gov]

Conclusions: The MR scans in SS show a rather distinctive pattern of supratentorial white matter lesions that always involve the corpus callosum. [n.neurology.org]

Show info

Primary Progressive Multiple Sclerosis

matter lesions [ncbi.nlm.nih.gov]

Additional diffusion-weighted imaging revealed restricted diffusion in the white matter lesions with a reduced apparent diffusion coefficient. [ncbi.nlm.nih.gov]

Lesion load was negatively correlated with cortical and subcortical grey matter volumes, but not with total white matter volume. [ncbi.nlm.nih.gov]

Show info

Binswanger Disease

Abstract OBJECTIVE: To identify the prevalence of MRI features of Binswanger's disease (BD), specifically MRI with diffuse white matter lesions and scattered multiple lacunes [zora.uzh.ch]

The white matter lesions are usually small, commonly grouped around the frontal and occipital horns and in the centrum semiovale. [radiopaedia.org]

[…] in the genesis of deep white matter lesions. [stroke.ahajournals.org]

Show info

CADASIL Syndrome

lesions on brain MRI. [ncbi.nlm.nih.gov]

matter lesions are also seen in asymptomatic individuals with the mutated gene. [8] While MRI is not used to diagnose CADASIL, it can show the progression of white matter [ipfs.io]

matter lesions subcortical infarcts in white matter, basal ganglia, and brain stem external capsules and temporal lobes are often affected Leukoencephalopathy is often present [en.wikibooks.org]

Show info

Microangiopathy

Classification The scale divides the white matter in periventricular and deep white matter, and region each is given a grade depending on the size and confluence of lesions [radiopaedia.org]

Scans were searched for white matter lesions and lacunar infarcts. [ncbi.nlm.nih.gov]

The Fazekas scale is used to simply quantify the amount of white matter T2 hyperintense lesions usually attributed to chronic small vessel ischemia, although clearly not all [radiopaedia.org]

Show info

Demyelinating Disease

Large, edematous white matter lesions were observed with the pathological feature of obvious demyelination yet preservation of astrocyte and axon, fundamentally different [ncbi.nlm.nih.gov]

Multiple Sclerosis (MS) -- characterized by more than one episode of neurologic deficits separated in time, attributable to CNS white matter lesions that are separated in [kobiljak.msu.edu]

MRI brain demonstrated one additional white matter lesion also consistent with a demyelinating process. Figure 1 MRI scans for case No 1 (A–I) and case No 2 (J–P). [jnnp.bmj.com]

Show info

Optic Neuritis

Axial, fluid-attenuated inversion recovery (FLAIR) image demonstrates bilateral periventricular white matter lesions. [emedicine.com]

While AZOOR previously has been linked to MS and demyelinating white matter lesions in the brain, our case seems unique due to concurrent development of AZOOR and retrobulbar [ncbi.nlm.nih.gov]

Eleven of the 29 patients (38%) had white matter T2/FLAIR (fluid-attenuated inversion recovery) lesions in the brain (not including the optic nerves). [emedicine.com]

Show info

Urea Cycle Disorder

Histopathologically, cortical atrophy, basal ganglia lesions and white matter damage may be observed. [symptoma.com]

Symmetric cystic lesions at the gray matter-white matter junction, especially in the sulcal depth of the frontal, parietal, hippocampal, and insular regions, are known early [ajnr.org]

[…] pathologic lesions resulting from hyperammonemic encephalopathy ( 13, 14 ). [ajnr.org]

Show info

Baló Concentric Sclerosis

A patient with a progressive left hemiparesis had a ring-enhancing, low-density right frontal white matter lesion. [ncbi.nlm.nih.gov]

Most of the white matter lesions also enhanced with contrast material. [ajnr.org]

CT and MRI showed additional lesions, but no features unique to this process. [n.neurology.org]

Show info

Subacute Sclerosing Panencephalitis

CT or MRI may show cortical atrophy or white matter lesions. [merckmanuals.com]

MRI can reveal multifocal white-matter lesions. Treatment The course of SSPE is variable, but it can last for years. There is no definitive treatment. [epilepsy.com]

Show info

Vascular Dementia

Major diagnostic difficulties ensue from the very frequent cases with white matter lesions, since their etiology and classification remain widely unknown. [ncbi.nlm.nih.gov]

Synergic effects of the degenerative element of AD and white matter lesions might be associated with oxidative stress damage in the MD group. 2015 Japan Geriatrics Society [ncbi.nlm.nih.gov]

It is primarily seen in patients with atherosclerosis and chronic hypertension and results from the accumulation of multiple white matter lesions or cortical infarcts, although [radiopaedia.org]

Show info

Hypoglycemic Encephalopathy

In addition to these lesions, which are consistent with hypoglycemia-induced brain damage, the cerebral white matter exhibited severe loss of myelin and axons with reactive [ncbi.nlm.nih.gov]

[…] involving bilateral cerebral cortex while previous subcortical white matter lesions disappeared ( 1 ). [i-mri.org]

lesions involving bilateral cerebral cortex were found on DWI, while previous subcortical white matter lesions disappeared. [ncbi.nlm.nih.gov]

Show info

Progressive Multifocal Leukoencephalopathy

matter lesions on brain magnetic resonance imaging (MRI). [ncbi.nlm.nih.gov]

OBJECTIVE: To analyze SWI hypointensities recently described in U-fibers and cortex adjacent to the white matter lesions of PML. [ncbi.nlm.nih.gov]

All three cases demonstrated the hyper-uptake of MET around the white matter lesions and hypo-uptake of FDG inside the lesions. [ncbi.nlm.nih.gov]

Show info

Postinfectious Encephalomyelitis

Emerging white matter lesions with slight restricted diffusion but without Gadolinium (Gd) enhancement. [springerplus.springeropen.com]

Multiple lesions in the deep and subcortical white matter are common, which is characteristic of demyelination (gray matter lesions sometimes accompany white matter lesions [myelitis.org]

MRI lesion patterns are generally recognized, but in all cases lesions are multifocal and involve mainly the supratentorial white matter: 18 -multifocal lesions of less than [slideplayer.com]

Show info

Acute Disseminated Encephalomyelitis

We found a discrepancy between the lesion size and the clinical deficits of the patient, actually the clinical improvement antedated the regression of the white matter lesions [ncbi.nlm.nih.gov]

Acute disseminated encephalomyelitis was confirmed by brain MRI which showed newly developed diffuse white matter lesions. [ncbi.nlm.nih.gov]

His clinical course was fluctuating and repeat imaging one week after presentation demonstrated interval development of characteristic white matter lesions. [ncbi.nlm.nih.gov]

Show info

Alexander Disease

Here, the authors report 3 genetically confirmed Alexander disease cases with focal central white matter lesions that, upon longitudinal clinical and radiologic evaluation [ncbi.nlm.nih.gov]

Mutation analysis of GFAP should be considered in patients with remitting neurological deficits, disseminated white matter lesions and absence of inflammatory CSF changes. [ncbi.nlm.nih.gov]

There were no white matter lesions or contrast enhancing lesions. [ncbi.nlm.nih.gov]

Show info

Encephalomyelitis

MRI showed leptomeningeal, peripheral spinal cord and periventricular cerebral white matter lesions in the brain, and polymerase chain reaction on cerebrospinal fluid detected [ncbi.nlm.nih.gov]

[…] have multiple lesions in the deep and subcortical white matter, characteristic of demyelination. • The periventricular white matter is often spared. 39. [slideshare.net]

Show info

Retrobulbar Neuritis

We report the case of a 26-year-old woman who developed progressive left hemiplegia, mental dysfunction, and had extensive bilateral cerebral white matter lesions diagnosed [ncbi.nlm.nih.gov]

Axial, fluid-attenuated inversion recovery (FLAIR) image demonstrates bilateral periventricular white matter lesions. [emedicine.com]

In summary, she experienced two episodes of neurological deficit, had left hemiplegia and mental dysfunction associated with multiple lesions in bilateral cerebral white matter [ncbi.nlm.nih.gov]

Show info

Marchiafava Bignami Disease

MRI of the brain demonstrated demyelination, edema and necrosis of the corpus callosum with extensive symmetrical subcortical white matter lesions. [ncbi.nlm.nih.gov]

An additional role could be played by microscopic white matter lesions and/or neocortical neuronal loss, which have been occasionally observed in post-mortem studies of MBD [ncbi.nlm.nih.gov]

In addition, multiple lesions were observed in bilateral frontoparietal subcortical white matter. [ncbi.nlm.nih.gov]

Show info

Neuromyelitis Optica

white matter lesions. [ncbi.nlm.nih.gov]

Specifically, long corticospinal lesions, hemispheric cerebral white matter lesions and periependymal lesions in the diencephalon, dorsal brainstem and white matter adjacent [ncbi.nlm.nih.gov]

MRI disclosed multiple white matter lesions and a long cervical spinal cord lesion extending to the medulla oblongata. [ncbi.nlm.nih.gov]

Show info

Jacobsen Syndrome

matter lesions. [ncbi.nlm.nih.gov]

Introduction: White matter lesions can have many causes. Two half-sisters (same mother) were presented to us for further examination. [thieme-connect.com]

", number "4", } TY - JOUR T1 - A case of Jacobsen syndrome with multifocal white matter lesions AU - Yu, Fang AU - Carter, John E AU - Bazan Iii, Carlos PY - 2016/7/1 Y1 [uthscsa.influuent.utsystem.edu]

Show info

Cerebral Angiitis

KW - Cerebral angiogram KW - MR imaging KW - Vasculitis KW - White matter lesion UR - UR - U2 - 10.1007/s00415-003-1021-4 DO - 10.1007/s00415-003-1021-4 M3 - Article VL - [scholars.northwestern.edu]

Multiple small deep infarcts, extensive deep white matter lesions, tumor-like lesions, or multiple gadolinium-enhanced lesions were observed only in PACNS, whereas cervical [n.neurology.org]

Focal white-matter lesions in brain of patients with inflammatory bowel disease. Lancet. 1995;345(8954):897–8. CrossRef PubMed 25. [springermedizin.de]

Show info

Periventricular Leukomalacia

Periventricular leukomalacia, inflammation and white matter lesions within the developing nervous system. Neuropathology, 22 pp. 106–132. [oro.open.ac.uk]

Telles and Gabriel Santos, Brain white matter lesions correlated to newborns death and lethality, Revista Brasileira de Saúde Materno Infantil, 6, 2, (231), (2006). [doi.org]

Marret, Role of tissue-plasminogen activator (t-PA) in a mouse model of neonatal white matter lesions: Interaction with plasmin inhibitors and anti-inflammatory drugs, Neuroscience [doi.org]

Show info

Cerebral Cortical Atrophy

matter lesions. [stroke.ahajournals.org]

[…] volume occurred in patients with progressing white matter lesions, whereas no such decrease occurred in patients with nonprogressive white matter lesions [87, 88]. [smw.ch]

White matter lesions have been repeatedly associated with gait disturbances and mobility difficulties. [betterhealthwhileaging.net]

Show info

Optic Papillitis

matter lesions, seen in Figures 5 and 6. [webeye.ophth.uiowa.edu]

matter lesions Intravenous corticosteriods: -hastens recovery by several weeks, no effect on visual function at 1 to 3 years -Decrease risk of clinical MS attacks Interferon [quizlet.com]

Magnetic resonance imaging (T2-weighted axial cut) shows multiple white-matter lesions in both cerebral hemispheres, including the periventricular regions. [arabmedmag.com]

Show info

Spinal Demyelination

[…] in the left occipital white matter lesions. [radiologykey.com]

The lesions of multiple sclerosis (MS) the lesions are scattered in the white matter, but often clustering near the ventricles. [dartmouth.edu]

[…] of marked hypointensity within the white matter lesions. 28. [slideshare.net]

Show info

Vitamin B12 Deficiency

Vitamin B 12 status has been associated with severity of white-matter lesions, especially periventricular in some, 97 but not all studies. 98 The partial reversal of white-matter [doi.org]

lesions and the known association of white-matter lesions with bipolar disorder, 61 we believe it is very likely that manic symptoms can be associated with vitamin B 12 deficiency [doi.org]

The disease process ranges from subclinical metabolic changes, to clinical symptoms, to irreversible structural damage, such as periventricular white-matter lesions. [doi.org]

Show info

2-Hydroxyglutaric Aciduria

matter lesions. [ncbi.nlm.nih.gov]

Diffusion-weighted images demonstrated increased diffusion of water molecules in the white-matter lesions. [ncbi.nlm.nih.gov]

Brain image revealed a symmetrical, extensive subcortical white matter lesion. [ncbi.nlm.nih.gov]

Show info

⚕ Symptoma®️ is a digital health assistant but no replacement for the opinion and judgement of medical professionals. By using this website you fully understand and accept that it shall not be used as a diagnostic system for decision-making. It absolutely must not be used to obtain, replace or overrule a clinical diagnosis by a healthcare professional. It is always for the medical professional to make the final diagnosis. The medical information provided on this website is of a general nature and can not substitute for the advice of a medical professional (for example, a qualified doctor or physician)! Information from the internet could and should NOT be solely used to offer or render a medical opinion or otherwise engage in the practice of medicine.