Wide Face: Causes & Reasons

Possible Causes for Wide Face

face, and abnormal hair whorl, and other manifestations (Sujansky et al., 1993, summary by Graw et al., 2000). (179613) (Updated 05-Apr-2021) MalaCards organs/tissues related [malacards.org]

Clinical aspects Features involve head (brachycephaly, wide face, midface hypoplasia, infraorbital creases, hypertelorism, anteverted nares, thin upper lip, thick lower lip [accessanesthesiology.mhmedical.com]

Features involve head (brachycephaly, wide face, midface hypoplasia, infraorbital creases, hypertelorism, anteverted nares, thin upper lip, thick lower lip, downturn mouth [accessanesthesiology.mhmedical.com]

X-Linked Syndromic Intellectual Disability Type Nascimento

[…] a rare, genetic developmental defect during embryogenesis syndrome characterized by severe intellectual disability, distinct dysmorphic facial features (i.e. triangular face [mendelian.co]

The main facial features were, a wide mouth, thick eyebrows with synophris, a short, wide neck with low posterior hairline. The face was said to be ""myxodematous"". [fdna.health]

(wide face, synophrys, prominent supraorbital ridges, deep-set, almond-shaped eyes, upslanting palpebral fissures, hypertelorism, depressed nasal bridge, prominent columella [ojrd.biomedcentral.com]

Ehlers-Danlos Syndrome Spondylodysplastic Type 1

wide-spaced eyes, proptosis ("bulging" eyes), narrow mouth, low-set ears, sparse scalp hair, flat face, wide forehead, blue sclerae, abnormal teeth, and cleft palate/bifid [rarediseases.info.nih.gov]

[…] forehead [ more ] 0000337 Craniosynostosis 0001363 Dislocated radial head 0003083 Flared metaphysis Flared wide portion of long bone 0003015 Flat face Flat facial shape 0012368 [rarediseases.info.nih.gov]

Fragile bones from low bone mineral density (osteopenia) Mild intellectual disabilities or learning disabilities Eye problems Characteristic facial features (triangular face [rarediseases.info.nih.gov]

Frontonasal Dysplasia Type 1

Features of this disorder include widely spaced eyes (ocular hypertelorism) and/or a vertical groove down the middle of the face. [rarediseases.org]

Description Frontonasal dysplasia is a condition that results from abnormal development of the head and face before birth. [medlineplus.gov]

Major physical characteristics may include widely spaced eyes (ocular hypertelorism); a flat broad nose; and/or a vertical groove down the middle of the face. [rarediseases.org]

Frontonasal Dysplasia Type 3

Features of this disorder include widely spaced eyes (ocular hypertelorism) and/or a vertical groove down the middle of the face. [rarediseases.org]

Major physical characteristics may include widely spaced eyes (ocular hypertelorism); a flat broad nose; and/or a vertical groove down the middle of the face. [rarediseases.org]

[…] dysplasia-1 Frontonasal dysplasia-2 Frontonasal dysplasia-3 General Discussion Frontonasal dysplasia is a rare disorder characterized by abnormal development of the head and face [rarediseases.org]

Progeroid Syndrome Type Petty

OMIM : 58 Fontaine progeroid syndrome is characterized by prenatal and postnatal growth retardation, decreased subcutaneous fat tissue, sparse hair, triangular face, widely [malacards.org]

[…] calvaria with large open anterior fontanel and wide metopic suture, broad forehead, small face, micrognathia), markedly diminished subcutaneous fat, cutis laxa and wrinkled [orpha.net]

[…] a rare premature aging syndrome characterized by pre-and postnatal growth retardation, a congenital premature-aged appearance with distinctive craniofacial dysmorphism (wide [orpha.net]

Ulnar Mammary Syndrome

People with UMS may have distinct facial features, including a wide face tapering to a prominent chin, and a broad nose. It has been associated with TBX3. [en.wikipedia.org]

People with UMS may have distinct facial features, including a wide face tapering to a prominent chin, and a broad nose. [1] [2] UMS is caused by mutations in the TBX3 gene [rarediseases.info.nih.gov]

face, nasal base and tip, and a protruding chin ( Fig 3 ). 5 Radiograph showing absence of the ulna and ulnar three digits. [ncbi.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 45

Luminescent gauge face. Wide 240º sweep from 0 to 400 bar. Bright, white face - easy to read. HP hose is not included. [sukelluskouluaalto.fi]

Aarskog-Scott Syndrome

including: Rounded face Wide-set eyes Slightly slanted eyes Drooping eyelids Small nose Front facing nostrils Mid-portion of the face is underdeveloped Wide groove above [knowyourdisease.com]

Rounded face. Impaired development of the mid section of the face. Wide set of eyes. Hairline resembling the peak of a widow. Crease below the lower lip. Droopy eyelids. [primehealthchannel.com]

Symptoms Short stature, rounded face, hairline has a "widow"s peak", wide set eyes with droopy eyelids, small nose with nostrils tipped forward [5], underdeveloped mid-portion [thefetus.net]

Macrocephaly Type Fryns

The most characteristic facial features for individuals with a clinical diagnosis of Fryns syndrome include a coarse face, wide-spaced eyes with cloudy corneas, a wide and [ncbi.nlm.nih.gov]

wide-set eyes, a wide and depressed nasal bridge with a broad nasal tip, a long philtrum, low-set and anomalous ears, a tented vermilion of the upper lip, wide mouth, and [ncbi.nlm.nih.gov]

[…] commonly a posterolateral Bochdalek hernia), diaphragmatic eventration, significant diaphragm hypoplasia, or diaphragm agenesis Characteristic facial appearance with a coarse face [ncbi.nlm.nih.gov]

Teebi-Naguib-Al Awadi Syndrome

Rounded face. Wide-set eyes and slightly slanted eyes with drooping eyelids. Small nose. Front-facing nostrils. Wide groove above the upper lip. [medigoo.com]

Clinical description Dysmorphic features include triangular or elongated face, hypertelorism, wide palpebral fissures, short, stubby nose with anteverted nostrils, long philtrum [orpha.net]

The face, fingers, and toes are most often affected. Symptoms Typical symptoms include: Disproportionately short stature. Underdeveloped mid-portion of the face. [medigoo.com]

Autosomal Dominant Aarskog-Scott Syndrome

Rounded face. Wide-set eyes and slightly slanted eyes with drooping eyelids. Small nose. Front-facing nostrils. Wide groove above the upper lip. [medigoo.com]

It is characterized by abnormal facial features (hypertelorism, wide philtrum, round face), short stature, genital anomalies, and skeletal dysplasia. [tp.amegroups.com]

widely spaced and prominent eyes, high anterior hairline, frontal bossing, depressed nasal bridge, short nose with anteverted nares, wide nasal bridge with a broad nasal [ncbi.nlm.nih.gov]

Frontonasal Dysplasia Type 2

Features of this disorder include widely spaced eyes (ocular hypertelorism) and/or a vertical groove down the middle of the face. [rarediseases.org]

Description Frontonasal dysplasia is a condition that results from abnormal development of the head and face before birth. [medlineplus.gov]

Major physical characteristics may include widely spaced eyes (ocular hypertelorism); a flat broad nose; and/or a vertical groove down the middle of the face. [rarediseases.org]

Monosomy 3p2

* Wide set eyes Diagnosis The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Chromosome 3, Monosomy 3p2. [checkorphan.org]

* Epicanthic folds * Droopy eyelids * Wide set eyes * Low set ears * Abnormal ears * Broad nose * Flat nose * Sunken chest * Scoliosis * Downturned mouth * Delayed puberty [checkorphan.org]

[…] below: * Growth delay * Retarded fetal growth * Severe mental retardation * Fused eyebrows * Excessive hair growth * Prominent forehead * Long head * Small head * Triangular face [checkorphan.org]

Lissencephaly Type 8

[…] classical lissencephaly, infants with Miller-Dieker syndrome may also malformations including microcephaly with a broad, high forehead; bitemporal hollowing; a relatively wide [rarediseases.org]

face; micrognathia; a long, thin upper lip; a short nose with upturned nostrils; low-set, malformed ears; polydactyly; abnormal palmar creases; cataracts and/or malformations [rarediseases.org]

Distal Trisomy 2p

His feet (fig2) are narrow with metatarsus varus, medial deviation of the second toe, and a wide sandal gap. [jmg.bmj.com]

His face is long and triangular with semilunar palpebral fissures (length 2.8 cm). There is a bulbous tip to the nose with a high bridge. The palate is high and arched. [jmg.bmj.com]

Chromosome 4q32.1-q32.2 Triplication Syndrome

The three sons share with their mother the following facial features: long midface, myopathic face, wide nasal bridge, short nose, short palpebral fissures, and low set, small [ashg.org]

Symptoms via clinical synopsis from OMIM: 58 Head And Neck Head: macrocephaly Head And Neck Face: frontal bossing short philtrum microretrognathia long midface hypoplastic [malacards.org]

[…] zygoma Head And Neck Eyes: ptosis downslanting palpebral fissures epicanthal folds small palpebral fissures Head And Neck Nose: wide nasal bridge short nose Head And Neck [malacards.org]

Muenke Syndrome

The prematurely joined skull bones lead to an abnormal/asymmetrical head or face shape with wide-set eyes (which may droop or bulge) and flattened cheekbones. [nicklauschildrens.org]

Hypertelorism: wide-set eyes. [chop.edu]

[…] their face: One side of the face may not match the other (facial asymmetry) Droopy eyelids (ptosis) Widely spaced eyes Eyes that bulge out (proptosis) Flat cheekbones Most [seattlechildrens.org]

Hypochondrogenesis

The head is often over-proportionally large and has an oval shape; the face is flat with widely-spaced eyes. [medical-genetics.de]

Their faces have a characteristic appearance with a flat ovalshaped face, wide-set eyes (hypertelorism), small chin, and, occasionally, an infant with hypochondrogenesis will [encyclopedia.com]

The face appears flat and oval-shaped, with widely spaced eyes, a small chin, and, in some cases, an opening in the roof of the mouth called a cleft palate. [checkorphan.org]

FG Syndrome Type 3

face Broad thumbs and halluces Congenital anomaly (corpus callosum, anal, cardiac, skeletal) Hypotonia, constipation, or feeding problems Characteristic behavior (affable [en.wikipedia.org]

[…] spaced eyes * Prominent lower lip * Small ears * Simple ears * Face wrinkles * Fine hair * Sparse hair * Epicanthal folds * Short space between eyelids * Down slanting space [checkorphan.org]

[…] hair downsweep Very small forehead Downslanted palpebral fissures Very close eyes Missing part of the upper eyelids Small, simple ears (≤10th percentile) Open mouth Long wide [en.wikipedia.org]

Autosomal-Recessive Robinow Syndrome

The 2 affected brothers had short stature, mesomelic and acromelic brachymelia, characteristic face with hypertelorism, wide palpebral fissures, midface hypoplasia and large [ncbi.nlm.nih.gov]

The two affected brothers had short stature, mesomelic and acromelic brachymelia, characteristic face with hypertelorism, wide palpebral fissures, midface hypoplasia and large [cags.org.ae]

Know about the common symptoms of this disorder: Fetus-shaped appearance of the face Abnormally small head Widely spaced eyes An inverted ‘v’-like shape of the upper lip Dental [hxbenefit.com]

Pfeiffer Syndrome Type 3

For example, a child with type 1 Pfeiffer syndrome may have a: High forehead Underdeveloped mid-face Widely spaced eyes Underdeveloped upper jaw Crowded teeth People born [verywellhealth.com]

Complex craniosynostosis Bulging and wide-set eyes Downward tilt to the eyelids A short nose A sunken appearance in the middle of the face An undeveloped upper jaw, causing [childrens.com]

[…] bulging and wide-set eyes, a high forehead, an underdeveloped upper jaw, and a beaked nose; hearing loss; and dental problems. [checkorphan.org]

Monosomy 18p

wide mouth, "carp-shaped"; flat or wide nose; large, deformed, lower-than-normal ears; ocular hypertelorism, drooping of the upper eyelid (ptosis), crossed eyes; Abnormally [vinmec.com]

However, such malformations often include an abnormally small head (microcephaly); a distinctively round face (that may change with age to appear relatively long); a wide, [rarediseases.org]

[…] phát triển trí tuệ ở mức độ trung bình The degree of craniofacial abnormalities varies from case to case including: abnormally small head (microcephaly); distinctive round face [vinmec.com]

Chromosome Xq Duplication

face, a small mouth and a thin pointed nose, major axial hypotonia, severe feeding problems and proneness to infections. [semanticscholar.org]

[…] was 18 years old the weight was 42,7 Kg (− 2 DS score) and her height was 153,2 cm (− 1 DS score): physical examination showed general facial hypotonia and nistagmus, long face [link.springer.com]

[…] are compared to those observed in patients reported in the literature, a distinct phenotype emerges including severe mental retardation, facial dysmorphic features with a wide [semanticscholar.org]

Glans Penis Cancer

Numbness, weakness, or pain in your face Doctors diagnose salivary gland cancer using a physical exam, imaging tests, and a biopsy. [medlineplus.gov]

[…] or neck difficulty opening your mouth widely numbness in your mouth or jaw muscle weakness on one side of your face difficulty swallowing (late-stage symptom) It’s unclear [healthline.com]

[…] jaw, ear, or neck Difficulty swallowing or opening mouth widely Fluid draining from the ear Facial numbness Sometimes, a dentist first notices these symptoms. [webmd.com]

Craniosynostosis - Mental Retardation - Heart Defects

Individuals with Noonan syndrome may have only a few or many of the physical or developmental differences listed below:</p><h3>Face and neck</h3><ul class="akh-steps"><li> [aboutkidshealth.ca]

<figure> <img src="https://assets.aboutkidshealth.ca/AKHAssets/Noonan_Eyes.jpg" alt="Close up of widely-spaced eyes and close up of eyes with ptosis" /> <figcaption>Top: [aboutkidshealth.ca]

Cri Du Chat Syndrome

The comparative analysis of the girl's phenotype in different developmental stages has revealed that microcephaly, flat occipital region, face asymmetry, wide spaced palpebral [ncbi.nlm.nih.gov]

Other features include a round, full face (“moon face”), widely spread eyes (hypertelorism), an extra fold of skin at the inner corners of the eyes (epicanthal folds), a flattened [rollercoaster.ie]

[…] individuals with Cri du Chat syndrome will have all of facial characteristics listed below: Facial Characteristics The most common facial characteristics are: Emily Rounded face [findresources.co.uk]

Van Bogaert-Hozay Syndrome

face, flat nose, auricular deformities, accentuated zygomatic arch, hypertelorism, micrognathia Eye abnormalities such as hypoplasia of the eyelashes and eyebrows, ptosis [de.zxc.wiki]

[…] lack of cilia on the middle third of the lower lid, iris coloboma, underdevelopedorbicularis oculi muscle, cataract,optic disk hypoplasia.Systemic features are fish-like face [eophtha.com]

[…] amputation-like changes, contractures of the finger joints, possibly also of the wrist and elbow joint Hypoplasia of the ulna near the wrist Short stature Facial abnormalities such as wide [de.zxc.wiki]

Macrosomia - Microphthalmia - Cleft Palate

Referring to the characteristic features of the head and face, they may include macrocephaly, occiput front wide, hypertelorism, large and low set ears, philtrum, a dimple [tr-ex.me]

Axenfeld-Rieger Syndrome Type 1

Many affected individuals have distinctive facial features such as widely spaced eyes (hypertelorism); a flattened mid-face with a broad, flat nasal bridge; and a prominent [encyclopedia.pub]

Hypertelorism (wide-set eyes) and a flattened face shape. Axenfeld-Rieger syndrome can also cause babies to have an unusually broad, prominent brow or forehead. [my.clevelandclinic.org]