Widely Spaced Nipples: Causes & Reasons

Possible Causes for Widely Spaced Nipples

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 30%-79% of people have these symptoms Anxiety Excessive, persistent [rarediseases.info.nih.gov]

A broad chest and widely spaced nipples. Arms that turn out slightly at the elbow. [medicinenet.com]

[…] worry and fear 0000739 Aortic arch aneurysm 0005113 Broad neck Increased width of neck Wide neck [ more ] 0000475 Dermatoglyphic ridges abnormal 0005689 Elevated hepatic [rarediseases.info.nih.gov]

Chromosome 19q13.11 Deletion Syndrome

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 5%-29% of people have these symptoms Bifid scrotum Cleft of scrotum [rarediseases.info.nih.gov]

[…] aplasia of the posterior corpus callosum, bilateral ptosis, oculomotor paralysis, down-slanting palpebral fissures, facial asymmetry, submucosal cleft palate, micrognathia, wide-spaced [pubfacts.com]

[…] lips [ more ] 0000233 Toe clinodactyly 0001863 Toe syndactyly Fused toes Webbed toes [ more ] 0001770 Underdeveloped nasal alae Underdeveloped tissue around nostril 0000430 Wide [rarediseases.info.nih.gov]

Fraser Syndrome

The patient had microphthalmia, blindness, widely spaced nipples, bifid ureter, syndactyly of the toes, and mental retardation. [ncbi.nlm.nih.gov]

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 Percent of people who have these symptoms is not available through [rarediseases.info.nih.gov]

Some of the other defects associated with Fraser Syndrome are hair growth extending from forehead to eyebrows, malformation of eyelid ducts, widely spaced nipples, along with [epainassist.com]

Noonan Syndrome

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 30%-79% of people have these symptoms Abnormal bleeding Bleeding [rarediseases.info.nih.gov]

spaced nipples Pectus excavatum or pectus carinatum (up to 90% have both, usually pectus carinatum superiorly and pectus excavatum inferiorly) Scoliosis As patients age, [pedclerk.bsd.uchicago.edu]

Clinical phenotype (facial dysmorphism, soft hair, short neck, broad chest, widely spaced nipples, mild pectus carinatum, deep palmar creases, unilateral cryptorchidism), [ncbi.nlm.nih.gov]

Cerebro-Facio-Thoracic Dysplasia

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 Wide nose Broad nose Increased breadth of nose Increased nasal breadth [rarediseases.info.nih.gov]

[…] eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Upslanted palpebral fissure Upward slanting of the opening between the eyelids 0000582 Wide [rarediseases.info.nih.gov]

Goldberg-Shprintzen Syndrome

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 Showing of 51 | Last updated: 2/1/2021 Cause Cause Goldberg-Shprintzen [rarediseases.info.nih.gov]

nipples. [jmg.bmj.com]

[…] eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Thick vermilion border Full lips Increased volume of lip Plump lips Prominent lips Thick lips [ more ] 0012471 Wide [rarediseases.info.nih.gov]

Monosomy 9p

Clinical examination showed a moon shaped face, flat occi-put, epicanthus, low nasal bridge, but also trigonocephaly, long philtrum, widely spaced nipples, dolichomesophalangy [publications.fondationlejeune.org]

Such abnormalities have included sudden episodes of uncontrolled electrical activity in the brain (seizures), widely spaced nipples, abnormal curvature of the spine, and/or [rarediseases.org]

spaced nipples 31/31 14/14 Stiff joints, scoliosis 9/21 8/22 Hernia 9/35 14/24 Cardiac murmur/cardiopathy 16/35 14/24 Abnormal external genitalia 15/36 10/24 Hand/foot Abnormal [publications.fondationlejeune.org]

2p15-p16.1 Deletion Syndrome

Some of the patients also had feeding problems in infancy, microcephaly, optic nerve hypoplasia and hydronephrosis, wide-spaced nipples, short stature, cortical dysplasia, [en.wikipedia.org]

Dysmorphic features: epicanthal folds, high narrow palate, retrognathia, cleft lip/palate, widely spaced nipples. [gene.sfari.org]

Craniosytosis Mental Retardation Syndrome of Lin and Gettig

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 Showing of 57 | Last updated: 5/1/2019 If you need medical advice [rarediseases.info.nih.gov]

Several types of combined malformations such as: KFS + frontonasal dysplasia + Sprengel deformity + widely spaced nipples + psotaxial hexadactily of the left foot, 4 KFS + [ispub.com]

[…] delayed Chiari I malformation Small downslanting palpebral fissures, posteriorly rotated ears, uveal coloboma, coloboma of the choroid and retina Fetal growth retardation, wide-spaced [thieme-connect.com]

X-Linked Syndromic Intellectual Disability Type Nascimento

Other physical features of the syndrome include excessive hair growth over the body, widely spaced nipples, dry skin or spots on the skin that are hyperpigmented, a micropenis [fdna.health]

spaced nipples, renal malformations). [ojrd.biomedcentral.com]

Unique facial features of the syndrome include a large head, deep-set eyes, large ears and a wide mouth with downward turned lip corners, a short neck, and a low hairline. [fdna.health]

X-Linked Syndromic Mental Retardation Type Snyder-Robinson

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 X-linked recessive inheritance 0001419 Showing of 36 | Last updated [rarediseases.info.nih.gov]

Increased body height 0000098 Thick lower lip vermilion Increased volume of lower lip Plump lower lip Prominent lower lip [ more ] 0000179 Webbed neck Neck webbing 0000465 Wide [rarediseases.info.nih.gov]

Short Rib-Polydactyly Syndrome Type Beemer-Langer

[…] eyes Widely spaced eyes [ more ] 0000316 Hypoplastic nipples Small nipples 0002557 Hypoplastic scapulae Small shoulder blade 0000882 Inguinal hernia 0000023 Intestinal malrotation [rarediseases.info.nih.gov]

] 0001831 Splenomegaly Increased spleen size 0001744 Thoracic dysplasia 0006644 Ventricular septal defect Hole in heart wall separating two lower heart chambers 0001629 Wide [rarediseases.info.nih.gov]

Bohring Opitz Syndrome

Some deformities of the trunk, including scoliosis, kyphosis, short or prominent sternum, widely spaced nipples and slender ribs are usually observed. [tandfonline.com]

spaced nipples, hypotonia, and BOS posture with long clenched fingers and right positional foot deformity, but no true contractures initially. [nature.com]

[…] alveolar ridges, high palate, long uvula, prominent eyes with proptosis and hypertelorism, persistent pupillary membranes, low-set dysplastic ears, micrognathia, short neck, wide [nature.com]

Onat Syndrome

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 Wide nasal bridge Broad nasal bridge Broad nasal root Broadened nasal [rarediseases.info.nih.gov]

Disproportionately small hands 0200055 Strabismus Cross-eyed Squint Squint eyes [ more ] 0000486 Subvalvular aortic stenosis Narrowing of blood vessel below aortic heart valve 0001682 Wide [rarediseases.info.nih.gov]

ADULT Syndrome

spaced nipples Absent nipples Small or underdeveloped (hypoplastic) nipples Skeletal Missing fingers and/or toes (ectrodactyly) Fused fingers and/or toes (syndactyly) Skin [nfed.org]

The 9-year-old patient has widely spaced nipples and congenital lacrimal duct obstruction. All affected individuals have very blond, thin and sparse hair. [nature.com]

[…] teeth) Premature loss of secondary teeth (<25 years) Breasts Underdeveloped breasts (breast hypoplasia) Underdevelopment of the mammary glands (mammary gland hypoplasia) Widely [nfed.org]

Lethal Neonatal Carnitine Palmitoyl Transferase II Deficiency

spaced nipples ABDOMEN: [Liver]; Hepatomegaly; Macrovesicular steatosis; Lipid accumulation in hepatocytes; Liver calcifications; [Gastrointestinal]; Poor feeding GENITOURINARY [genome.jp]

[…] cardiomyopathy; Thickened myocardium; Arrhythmias; Lipid accumulation in heart RESPIRATORY: Respiratory distress; Apnea; Respiratory failure CHEST: [External features]; Widely [genome.jp]

Female Infertility due to Anovulation

spaced nipples, sexual infantilism. [medical-dictionary.thefreedictionary.com]

If an infant has a wide or webbed neck, a broad chest, and widely spaced nipples, or if, as a girl grows, she has a short stature and undeveloped ovaries, TS may be present [medicalnewstoday.com]

spaced nipples, cubitus valgus ;, nail dysplasia, short fourth metacarpals/metatarsals High arched palate, low-set posterior hairline Webbed neck : skin folds along the side [amboss.com]

Chromosome 18p Deletion Syndrome

spaced nipples (12%) Hand anomalies Tapered fingers (35%) Proximal thumb (33-65%) with short first metacarpal Transverse palmar creases (23%) High whorl patterns on fingertips [en.wikibooks.org]

Additional findings include a webbed neck, widely spaced nipples, clinodactyly of the fifth finger, syndactyly, and strabismus. [synapse.koreamed.org]

Mosaic Monosomy X

spaced nipples niple hypoplasia (hypoplastic nipples) axillary air absent aortic anomalies ( 12640386 ) aortic coarctation aortic cystic medial necrosis dissecting aneurysms [humpath.com]

[…] chest and widely spaced nipples arms that turn out slightly at the elbow congenital heart defects or heart murmur scoliosis (curving of the spine) or other skeletal abnormalities [rarediseases.info.nih.gov]

spaced nipples * Short neck * Low hairline * High narrow-arched palate * Short fourth metacarpals * Pigmented nevi * Hypoplastic nails * Horseshoe kidney * Mitral valve prolapse [checkorphan.org]

46,XX Ovarian Dysgenesis-Short Stature Syndrome

[…] without hormonal treatment, average height is 145cm); ovarian dysgenesis (streak ovary); this is the most common cause of primary amenorrhea; infertility; shield chest with widely-spaced [wikilectures.eu]

spaced nipples, sexual infantilism. [medical-dictionary.thefreedictionary.com]

spaced nipples 758.6 Excludes pure gonadal dysgenesis ( 752.7 ) Applies To Ovarian dysgenesis Turner's syndrome XO syndrome ICD-9-CM Volume 2 Index entries containing back-references [icd9data.com]

Disproportionate Short Stature - Ptosis - Valvular Heart Lesions

For example: A broad chest with widely spaced nipples. A wide carrying angle (this is the angle between the forearm and the hip when the arm is held by the side). [patient.info]

spaced nipples, hyperconvex fingernails and toenails; may be normal appearing; decreased growth velocity and delayed puberty Follicle-stimulating hormone, karyotyping If [aafp.org]

Fetal Warfarin Syndrome

Symptoms and Signs Symptoms include low birth weight, seizures, reduced muscle tone, deafness, feeding difficulty, shortened fingers, widely spaced nipples, and failure to [dianamossop.com]

spaced nipples * Deafness * Feeding difficulty * Failure to thrive Causes - Fetal warfarin syndrome Not supplied. [checkorphan.org]

spaced nipples and the Dandy-Walker malformation. [symptoma.com]

Ring Chromosome 10

Decreased length of neck 0000470 Tapered finger Tapered fingertips Tapering fingers [ more ] 0001182 Thin vermilion border Decreased volume of lip Thin lips [ more ] 0000233 Wide [rarediseases.info.nih.gov]

Disorder of Sex Development - Intellectual Disability Syndrome

[…] neck and abdomen 0010306 Spina bifida occulta 0003298 Synophrys Monobrow Unibrow [ more ] 0000664 Thin vermilion border Decreased volume of lip Thin lips [ more ] 0000233 Wide [rarediseases.info.nih.gov]

Partial Monosomy 18q

spaced nipples (12%) Hand anomalies Tapered fingers (35%) Proximal thumb (33-65%) with short first metacarpal Transverse palmar creases (23%) High whorl patterns on fingertips [en.wikibooks.org]

Hernias Long fingers/toes Narrow feet Widely spaced nipples Irregular dental development Precocious puberty Abnormal genitalia Hypopigmentation of skin/hair Excessive drooling [9pminus.org]

Broad trunk 19 Webbed neck 16 Funnel chest 9 Hypothyroid 8 High palate 8 Abnormal toes 7 Cyclops (incompatible with life) 5% Widely spaced nipples 7 Cebocephaly (incompatible [labmed.hallym.ac.kr]

Ring Chromosome 1

[…] includes the TCF4 gene (located at 52,889,562-52,946,887), features of Pitt-Hopkins may be present, including abnormal corpus callosum; short neck; small penis; accessory and wide-spaced [en.wikipedia.org]

nipples; broad or clubbed fingers; and sacral dimple. [en.wikipedia.org]

46,XX Ovotesticular Disorder of Sex Development

spaced nipples, cubitus valgus ;, nail dysplasia, short fourth metacarpals/metatarsals High arched palate, low-set posterior hairline Webbed neck : skin folds along the side [amboss.com]

Turner's syndrome (45, XO karyotype) which is the most common form of female gonadal dysgenesis indicates physical characteristics such as webbed neck, widely spaced nipples [advbiores.net]

Parana Hard-Skin Syndrome

Additional reported features include mild spasticity, slight and nonprogressive ataxia, hyperopia, multiple pigmented nevi, widely spaced nipples, and clinodactyly. [mendelian.co]

Pigeon chest 0000768 Round face Circular face Round facial appearance Round facial shape [ more ] 0000311 Short stature Decreased body height Small stature [ more ] 0004322 Wide [rarediseases.info.nih.gov]

Ring Chromosome 18

nipples; broad or clubbed fingers; and sacral dimple. [en.wikipedia.org]

Partial Trisomy 4p Syndrome

Chest and skeletal malformations consist of widely spaced nipples, abnormal vertebral and pelvic stance, hypoplastic ribs and limb abnormalities. [moh-it.pure.elsevier.com]

[…] intermamillary distance Wide-spaced nipples Widely spaced nipples Widely-spaced nipples [ more ] 0006610 30%-79% of people have these symptoms Camptodactyly of finger Permanent [rarediseases.info.nih.gov]

* Widely spaced nipples * Absent ribs * Additional ribs * Joint contractures * Behaviour problems Causes - Chromosome 4- Trisomy 4p * Abnormal EEG * Behaviour problems * [checkorphan.org]