Xerostomia: Causes & Reasons

Possible Causes for Xerostomia

Xerostomia was significantly more common and severe in patients (46.9%) than in healthy controls, whereas the saliva flow rates did not differ. [ncbi.nlm.nih.gov]

Xerostomia is the most consistent and bothersome side effect of radiation therapy. A preventive approach and early treatment are important. [ncbi.nlm.nih.gov]

Poor oral hygiene is commonplace among this group, as is smoking and xerostomia, which also contribute to the development of denture stomatitis. [ncbi.nlm.nih.gov]

Sjögren Syndrome

Xerostomia Other names Dry mouth,[1] dry mouth syndrome[2] Xerostomia, also known as dry mouth,[1] is dryness in the mouth, which may be associated with a change in the composition [en.wikipedia.org]

Sjogren's syndrome, involving sicca symptoms with xerostomia, stomatitis, and considerable pain is a difficult-to-treat autoimmune disease where the treatment options are [ncbi.nlm.nih.gov]

Eye dryness and xerostomia were assessed by the Schirmer's test, the Fox test and the visual analogue scale (VAS). [ncbi.nlm.nih.gov]

Radiation Stomatitis

Glycerol Spray for Management of Psychotropic Drug-Induced Xerostomia Xerostomia (mouth dryness) often occurs as an unwanted effect of psychotropic drugs. [medlife.pharmacy]

Pilocarpine Troches for Xerostomia Pilocarpine is indicated for the treatment of xerostomia secondary to radiation therapy of the head and neck. [pottershouserx.com]

Archives of Oral Biology. 2011 April; 56(4): 395-400 Pilocarpine Troches for Xerostomia Pilocarpine is indicated for the treatment of xerostomia secondary to radiation therapy [medlife.pharmacy]

Triple A Syndrome

Conclusion We recommend the investigation of salivation in all patients with triple A syndrome and treatment of xerostomia in order to ease swallowing. [ncbi.nlm.nih.gov]

The importance of this case report is to highlight the necessity of referring the young patients with xerostomia from dental to medical specialists. [ncbi.nlm.nih.gov]

It has also been reported dry mouth as a consequence of xerostomia which leads to carious teeth as it is described in Sjögren syndrome [ 23 ]. [hon.ch]

Primary Biliary Cirrhosis

She was 38 years old and was admitted to our hospital for generalized pruritus, xerostomia, xerophthalmia, fatigue, and reticulonodular changes on her chest X-ray. [ncbi.nlm.nih.gov]

Pinto A: Management of xerostomia and other complications of Sjögren's syndrome. Oral Maxillofac Surg Clin North Am 2014;26:63-73. [karger.com]

(25%) Hyperpigmentation (25%) Splenomegaly (15%) Jaundice (10%) Xanthelasma (10%) - In late stages of the disease Sicca syndrome (50-75%) - Xerophthalmia (ie, dry eyes), xerostomia [emedicine.medscape.com]

Systemic Scleroderma

Abstract Scleroderma is a disorder involving oral and facial tissues, with skin hardening, thin lips, deep wrinkles, xerostomia, tongue rigidity, and microstomia. [ncbi.nlm.nih.gov]

(SSc) is an autoimmune disease that affects connective tissue, resulting in hardening skin, reduced vascular perfusion, gingival fibrosis, enlarged periodontal ligament, xerostomia [ncbi.nlm.nih.gov]

Muscle weakness Muscular weakness 0001324 Osteolysis Breakdown of bone 0002797 Pulmonary fibrosis 0002206 Skin ulcer Open skin sore 0200042 Telangiectasia of the skin 0100585 Xerostomia [rarediseases.info.nih.gov]

Lambert-Eaton Syndrome

 She also described intense muscular pain, a loss of 10 kg in 10 months, xerostomia, and reduction of the libido. 3. ??What are the signs and symptoms??? [slideshare.net]

Both patients in this report presented xerostomia and reduction of the libido. [scielo.br]

A 68‑year‑old male patient presented with a 6‑month history of progressive weakness of the proximal limbs and a 2‑month history of xerostomia. [spandidos-publications.com]

Diffuse Cutaneous Systemic Scleroderma

Rheumatoid Arthritis

Sjogren’s syndrome is an autoimmune condition that affects exocrine gland function, leading to a reduction in tear production (keratoconjunctivitis sicca), oral dryness (xerostomia [hopkinsarthritis.org]

Sjögren’s syndrome used in this and other studies, 36, 37 the frequency of the diagnosis depends heavily on the availability of specific tests for the evaluation of possible xerostomia [doi.org]

Amyloidosis

Areas of swelling, hemorrhages under the skin (purpura), hair loss (alopecia), inflammation of the tongue (glossitis) and a dry mouth (xerostomia) may also be present. [rarediseases.org]

Multicentric Castleman's Disease

Additional complaints consistent with MCD are xerostomia, rash and neurological deficits. [symptoma.com]

Radiotherapy

Intensity-modulated radiation therapy (IMRT) is an increasingly available approach to the prevention of xerostomia. [emedicine.medscape.com]

METHODS: A Markov model was used to simulate radiation therapy-induced dysphagia and xerostomia in HNCPs. [ncbi.nlm.nih.gov]

Given in a daily dose, amifostine is to be used in the prevention of radiation-induced xerostomia in the postoperative setting. [emedicine.medscape.com]

Amantadine Toxicity

[…] capsules Treatment of dyskinesia or “off” episodes in patients with Parkinson disease receiving concomitant levodopa-based therapy 100 98 Gastrointestinal: Constipation (13%), xerostomia [5minuteconsult.com]

Belladonna Tincture

Side effects include xerostomia, hoarseness, visual disorders. [tankonyvtar.hu]

[…] extract as a flavouring Hyperthyroidism Ephedra sinica Ephedra, Ma Huang Ephedrae herba Ephedra Ephedra intermedia Zhong Ma Huang Ephedra equisetina Muzei Ma Huang Dry mouth (xerostomia [tankonyvtar.hu]

Anticholinergic

OBJECTIVE: The aim was to study whether the anticholinergic burden of drugs is related to xerostomia and salivary secretion among community-dwelling elderly people. [ncbi.nlm.nih.gov]

The frequency of patients with a high AIS score, greater than 5, was significantly higher in patients who received laxatives and treatments of xerostomia. [ncbi.nlm.nih.gov]

‘The administration of antihypertensive and anticholinergic medications also impairs salivary functions and promotes xerostomia.’ [en.oxforddictionaries.com]

Diphenhydramine

While xerostomia can be a mild aggravation for the patient and may not appear to be clinically relevant, chronic xerostomia can increase the risk for dental caries as well [ebmconsult.com]

Closely All Interactions Sort By: Adverse Effects Frequency Not Defined Sedation Confusion Anticholinergic effects May decrease cognitive function in geriatric patients Xerostomia [reference.medscape.com]

Incidence not known Mild drowsiness / Early / 22.1-22.1 restlessness / Early / 1.0-10.0 asthenia / Delayed / 4.4-4.4 headache / Early / 2.5-2.5 dizziness / Early / 2.5-2.5 xerostomia [pdr.net]

Oral Candidiasis

In patients with T1D and neuropathy, more cases of xerostomia and decreased salivary flow were reported. [dentalcare.com]

[…] opportunistic pathogen linked to immune compromise–eg, with AIDS, immunosuppression in transplants, chemotherapy, corticosteroids, DM, ↑ age, poor health, inherited immune defects, xerostomia [medical-dictionary.thefreedictionary.com]

Moreover, tongue pain and xerostomia were evaluated using visual analog score (VAS). [ncbi.nlm.nih.gov]

TTR Amyloidosis with Polyneuropathy

[…] autonomic disturbances were not present in most patients when seen the first time, orthostatic hypotension, diarrhea/stypsis, erectile dysfunction, urinary incontinence, xerostomia [content.iospress.com]

Areas of swelling, hemorrhages under the skin (purpura), hair loss (alopecia), inflammation of the tongue (glossitis) and a dry mouth (xerostomia) may also be present. [rarediseases.org]

At last follow-up, autonomic involvement (orthostatic hypotension, diarrhea/stypsis, erectile dysfunction, urinary incontinence, xerostomia) paralleled sensory and motor dysfunction [content.iospress.com]

Acute Amphetamine Intoxication

CRC Press, 29.11.2006 - 560 Seiten The Color Atlas of Human Poisoning and Envenoming is the only full-color resource available for the immediate visual association and the rapid identification of envenoming species, resultant lesions, clinical outcomes of envenoming or poisoning, and recommended treatment strategies to[…] [books.google.de]

Acute Kidney Injury

Definition (NCI) Acute renal failure caused by the cell death of the renal tubules. Causes include nephrotoxins, cytotoxic drugs, and antibiotics. Definition (MSH) Acute kidney failure resulting from destruction of EPITHELIAL CELLS of the KIDNEY TUBULES. It is commonly attributed to exposure to toxic agents or renal[…] [fpnotebook.com]

Hemochromatosis

What is hereditary hemochromatosis? Hereditary hemochromatosis is an inherited (genetic) disorder in which there is excessive accumulation of iron in the body (iron overload). It is a common genetic disorder among Caucasians in the United States, affecting approximately 1million people in the United States. Individuals[…] [medicinenet.com]

Tricyclic Antidepressant

The blockade of these receptors gives as a result: Anticholinergic (atropine-like) effects: blurred vision, xerostomia, urinary retention, constipation and narrow angle glaucoma [pharmacologycorner.com]

Radiation Exposure

It is used clinically to prevent xerostomia in patients undergoing radiation therapy. [msdmanuals.com]

It prevents xerostomia in patients undergoing radiation therapy. [merckmanuals.com]

Dehydration

Abstract Exercise-induced dehydration can lead to impaired perfusion to multiple regional tissues and organs. We propose that the impact of dehydration on regional blood flow and metabolism is dependent on the extent of the cardiovascular demand imposed by exercise, with the greatest physiological strain seen when[…] [ncbi.nlm.nih.gov]

Panic Disorder

Snapshot A 30-year-old man arrives at the ED stating in distress that he had " a heart attack." The event started suddenly and was associated with diaphoresis, chest pain, tachycardia, and tachypnea. Troponins and ECG are within normal limits. Upon further questioning, he reports some numbing around his lips and[…] [step2.medbullets.com]

Salivary Gland Disorder

Causes severe xerostomia. 12. [slideshare.net]

Individuals with xerostomia complain of dry mouth and throat and associated difficulty with mastication and swallowing. [asams.org]

점액저류낭 Mucous retention cyst of salivary gland K11.6 두꺼비종 Ranula K11.7 침분비의 장애 Disturbances of salivary secretion K11.7 침분비저하 Hypoptyalism K11.7 침과다증 Ptyalism K11.7 구강건조증 Xerostomia [andwin.co.kr]

Sialadenitis

Sialadenitis was present in 25 patients and xerostomia in 22 patients. [ncbi.nlm.nih.gov]

Patients with diseases and/or medication causing xerostomia were excluded. Patients underwent salivary gland scintigraphy with 99Tc (10mCi). [ncbi.nlm.nih.gov]

The aim of this study is to clarify the therapeutic effects of LIPUS on xerostomia in SS. [ncbi.nlm.nih.gov]

Antidepressant

antipsychotics, dopamine antagonists, and nonpsychiatric MAOIs (eg, linezolid, IV methylene blue) May cause anticholinergic effects; use with caution in patients with xerostomia [reference.medscape.com]

Temporal Arteritis

Giant cell arteritis with arteritic anterior ischemic optic neuropathy has rarely been diagnosed in Taiwan. Recently, we encountered a 76-year-old Taiwanese patient who presented with right visual impairment and marked pale swelling of his right disc. He also suffered body weight loss, general malaise and many typical[…] [ncbi.nlm.nih.gov]

Hepatopathy

Anstee QM, Jones DEJ. Liver and biliary tract disease. In: Walker BR, Colledge NR, Ralston SH, Penman ID, eds. Davidson's Principles and Practice of Medicine. 22nd ed. Philadelphia, PA: Elsevier; 2014:chap 23. Martin P. Approach to the patient with liver disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th[…] [nlm.nih.gov]