With regard to internal causes, 30 patients presented with a positive patch test result for metals, but only 2 presented with exacerbations of the lesions after a challenge test. [emedicine.medscape.com]

• Fever

  […] with the preservation of water and glycerol, decreasing the frequency and severity of pompholyx exacerbations. [12] Atopy As many as 50% of patients with dyshidrotic eczema have reportedly had personal or familial atopic diathesis (eczema, asthma, hay fever [emedicine.medscape.com]

• Dermatitis

  Kilpikari, I., «Occupational contact dermatitis among rubber workers.» Contact Dermatitis. Vol. 8, p. 359-362. (1982). ▲8. [reptox.cnesst.gouv.qc.ca]

  Dermatitis. 2006 Dec. 17(4):165-81. [Medline]. Magina S, Barros MA, Ferreira JA, Mesquita-Guimaraes J. Atopy, nickel sensitivity, occupation, and clinical patterns in different types of hand dermatitis. Am J Contact Dermat. 2003 Jun. 14(2):63-8. [emedicine.medscape.com]

• Eczema

  In these cases, the eczema is usually more severe. [emedicine.medscape.com]

  Hervé-Bazin, B. et al., «Occupational eczema from N-isopropyl-N'-phenylparaphenylenediamine (IPPD) and N-dimethyl-1,3 butyl-N'-phenylparaphenylediamine (DMPPD).» Contact Dermatitis. Vol. 3, p. 1-15. (1977). [AP-050186] ▲5. [reptox.cnesst.gouv.qc.ca]

• Erythema

  Improvement in pruritus, erythema, vesicles, and hand dermatitis with fewer or no signs of relapse has been obtained after onabotulinumtoxinA injection. [2] Dyshidrotic eczema may be associated with atopy and familial atopy. [emedicine.medscape.com]

• Pruritus

  Improvement in pruritus, erythema, vesicles, and hand dermatitis with fewer or no signs of relapse has been obtained after onabotulinumtoxinA injection. [2] Dyshidrotic eczema may be associated with atopy and familial atopy. [emedicine.medscape.com]

• Eruptions

  Dyshidrosislike eczematous eruptions with the use of intravenous immunoglobulin (IVIG) infusions have been reported. [emedicine.medscape.com]

Further workup ruled out contact dermatitis, polymorphic light eruption, and heat as the culprit, confirming that the reaction was due to true photosensitivity rather than to photoaggravation. [14] Pompholyx caused by UVA exposure may possibly be considered [emedicine.medscape.com]

[…] of dyshidrotic eczema (pompholyx) Treatments for dyshidrotic eczema (pompholyx) are as follows: First-line treatment includes high-strength topical steroids and cold compresses; systemic steroids also used Treatment for bullae (blisters): Compresses [emedicine.medscape.com]

Prognosis of Dyshidrotic Eczema Dyshidrotic eczema follows a chronic, intermittent course, with fewer episodes occurring after middle age. Some mildly affected patients experience spontaneous resolution within 2-3 weeks. [emedicine.medscape.com]

Etiology The hypothesis of sweat gland dysfunction has been refuted because vesicles have not been shown to be associated with sweat ducts. [emedicine.medscape.com]

Dyshidrosis: epidemiology, clinical characteristics, and therapy. Dermatitis. 2006 Dec. 17(4):165-81. [Medline]. Magina S, Barros MA, Ferreira JA, Mesquita-Guimaraes J. [emedicine.medscape.com]