Presentation
Abstract Eleven patients presenting with acute necrotizing ulcerative gingivitis (ANUG) collected 24-hour urine samples during and after the course of their ANUG. [ncbi.nlm.nih.gov]
Fellow of the Dazian Foundation for Medical Research, 1952-53. 3 Present address: Lt. J. G., Naval Medical School, U. S. [jci.org]
It presents at puberty because of reduced adrenal androgen production ( hypogonadism ). Females with 17-hydroxylase deficiency present with delayed puberty : they do not menstruate, and breasts and pubic hair fail to develop. [dermnetnz.org]
In the present report, a rare case of an androgen-secreting adrenal tumor is presented. [spandidos-publications.com]
Patients almost always present with symptoms by age 5 years. Patients usually present with onset of symptoms in the first year of life but may present in early childhood. [emedicine.medscape.com]
Entire Body System
- Swelling
Following are the clinical indications for performing the 17-Hydroxycorticosteroids Urine Test: Dehydration Weight loss Altered mental status Nausea Vomiting Diarrhea Fatigue Craving for salty food Swelling of the face (“moon face”) Altered posture (“ [dovemed.com]
DI COOMBS DIRETTO TEST DI COOMBS INDIRETTO TEST DI DEGRANULAZIONE DEI BASOFILI TEST DI GRAVIDANZA TEST DI KERRY TEST DI RESISTENZA ALLA DECONDENSAZIONE CROMATINICA TEST DI SPECIFICITA' PER IGM ANTI ROSOLIA TEST DI SOPRAVVIVENZA NEMASPERMICA TEST DI SWELLING [eurolabgiovinazzo.it]
Gastrointestinal
- Vomiting
Dehydration Weight loss Change in mental state Motion sickness Vomiting Diarrhea Fatigue Savory foods cravings Facial edema (moon face) Kyphosis (buffalo hump) Abnormal hair growth What do the results of the 17-Ηydroxycorticosteroids test in urine mean [athenslab.gr]
Following are the clinical indications for performing the 17-Hydroxycorticosteroids Urine Test: Dehydration Weight loss Altered mental status Nausea Vomiting Diarrhea Fatigue Craving for salty food Swelling of the face (“moon face”) Altered posture (“ [dovemed.com]
It presents in early infancy with vomiting, salt wasting and genital ambiguity. Tests reveal: Low sodium High potassium High urinary DHEA Low urinary cortisol metabolites (namely 17 hydroxycorticosteroid). [dermnetnz.org]
" may indicate: Gastrointestinal disorder, such as malabsorption syndrome Taking these drugs may affect test results: Acetazolzmide Ammonium chloride Thiazide diuretics Other factors that may affect test results: Too much dietary potassium Excessive vomiting [cushings-help.com]
Advise parents and/or caregivers to contact their pediatric endocrinologist if vomiting or diarrhea is present and the child cannot tolerate oral fluids and medication. [emedicine.medscape.com]
- Nausea
Following are the clinical indications for performing the 17-Hydroxycorticosteroids Urine Test: Dehydration Weight loss Altered mental status Nausea Vomiting Diarrhea Fatigue Craving for salty food Swelling of the face (“moon face”) Altered posture (“ [dovemed.com]
Five days after delivery she develops anorexia, nausea, vomiting, and confusion. At this time her blood pressure is 80/40 mmHg. The physical examination is otherwise unremarkable. [ucsdlabmed.wikidot.com]
Side effects include nausea, anorexia, diarrhea, hypercholesterolemia, and hepatotoxicity. [glowm.com]
Skin
- Hirsutism
The frequency of late-onset CAH 21 deficiency in hirsute and PCOS women ranges from 0% to 30%. 32, 33, 34 Hirsute patients diagnosed with CAH were more likely to have severe hirsutism, virilization, short stature, family history of hirsutism, earlier [glowm.com]
On DermNet NZ Acne Hirsutism Male pattern hair loss Other websites Medscape Reference Congenital adrenal hyperplasia Congenital Adrenal Hyperplasia C-17 Hydroxylase Deficiency C-11 Hydroxylase Deficiency Adrenal disorders - Endocrine web Books about skin [dermnetnz.org]
TOC | ENDO CUSHING'S SYNDROME (HYPERCORTISOLISM) SX | DX | Causes | RX REF: Cushings2008.pdf SX: the classic Sx are moon facies, central obesity, plethora, red striae, hirsutism, ecchymoses, proximal muscle weakness, and osteoporosis; hypokalemia, hypertension [enotes.tripod.com]
If Cushing’s syndrome is suspected on clinical grounds (obesity limited to trunk, moon face, buffalo hump, abdominal purple striae, muscular weakness, osteoporosis, hypertension, dys- and amenorrhea, mental disturbances, hirsutism, virilization, diabetes [ucsdlabmed.wikidot.com]
- Alopecia
Virilisation : deepened voice, small breasts, increased muscle bulk, enlarged clitoris, increased libido Accelerated bone age Absent or irregular menstrual periods Male pattern of hair growth ( hirsutism ) Oily skin ( seborrhoea ) Acne Androgenetic alopecia [dermnetnz.org]
Diabetes mellitus (52%) Gonadal failure (12–17%) Gonadal failure (3.5–3.6%) Vitiligo (8–9%) Vitiligo (4.5%) Hypoparathyroidism (82%) Celiac disease (ND) Chronic mucocutaneous candidiasis (73–78%) Myasthenia gravis (ND) Chronic active hepatitis (11–13%) Alopecia [glowm.com]
- Acne Vulgaris
vulgaris in patients 12 years of age and older.CortisoneA naturally occurring glucocorticoid. [go.drugbank.com]
Obstet Gynecol 4: 388, 1976 89 Rose LI, Newmark SP, Strauss JS: Adrenocortical hydroxylase deficiencies in acne vulgaris. [glowm.com]
Psychiatrical
- Increased Libido
[…] muscle bulk, enlarged clitoris, increased libido Accelerated bone age Absent or irregular menstrual periods Male pattern of hair growth ( hirsutism ) Oily skin ( seborrhoea ) Acne Androgenetic alopecia Late-onset in males Premature puberty Accelerated [dermnetnz.org]
Urogenital
- Amenorrhea
If Cushing’s syndrome is suspected on clinical grounds (obesity limited to trunk, moon face, buffalo hump, abdominal purple striae, muscular weakness, osteoporosis, hypertension, dys- and amenorrhea, mental disturbances, hirsutism, virilization, diabetes [ucsdlabmed.wikidot.com]
The hirsutism typically is moderate, and may be associated with acne and amenorrhea in approximately 40% and 50% of cases, respectively. 135, 139 Highly elevated circulating levels of DHEA, DHEAS, testosterone, and androstenedione are suggestive of adrenal [glowm.com]
- Clitoromegaly
The patients with the late-onset form of CAH 21 have varying degrees of precocious puberty, hirsutism, cystic acne, clitoromegaly, short stature, male pattern baldness, anovulation, oligomenorrhea, and infertility. 5, 30, 31 Virilization is rare. [glowm.com]
Workup
Review Topic QID: 105581 2 Begin a workup for 17 alpha-hydroxylase deficiency 3 Begin a workup for 21-hydroxylase deficiency 4 Begin a workup for 11 beta-hydroxylase deficiency M2 Select Answer to see Preferred Response PREFERRED RESPONSE 5 Sorry, this [medbullets.com]
By the end of this session the reader should be able to: Discuss the adrenal-pituitary-hypothalamus axis, including relationships between hormones and steroids in each Discuss the use of serum cortisol in the workup of hypercortisolism and hypocortisolism [ucsdlabmed.wikidot.com]
Microbiology
- Chlamydia
RICERCA SU URINE CHLAMYDIA RICERCA DIRETTA SU TAMPONE CERVICALE E URETRALE (MASCHILE E FEMMINILE) CATENE LEGGERE KAPPA E LAMBDA SIERICHE CATECOLAMINE PLASMATICHE ED URINARIE (ADRENALINA, NORADRENALINA E DOPAMINA) CARBOSSIEMOGLOBINA CARBAMAZEPINA TRANSFERRINA [labanalisicroceazzurra.it]
TRACHOMATIS IGG QUALITATIVO ANTICORPI ANTI CHLAMYDIA TRACHOMATIS IGG QUANTITATIVO ANTICORPI ANTI CHLAMYDIA TRACHOMATIS IGM QUALITATIVO ANTICORPI ANTI CHLAMYDIA TRACHOMATIS IGM QUANTITATIVO ANTICORPI ANTI CHLAMYDIA PNEUMONIAE IGG QUALITATIVO ANTICORPI [eurolabgiovinazzo.it]
Ab CHLAMYDIA Ag CHLORURE CHOLERA CHOLESTEROL CK-MB CK-TOTAL CLOSTRIDIUM DIFFICILE TOXIN A & B CMV IgG CMV IgM CO2 COAGULATION COLORATION BLEU DE METHYLENE COLORATION BLEU DE METHYLENE COLORATION ZEIHL NEELSEN COOMBS DIRECT COOMBS INDIRECT CORTISOL COTININE [ephatamedic.com]
ANTI CHLAMYDIA TRACHOMATIS Ac. ANTI CITRULLINA (Anti CCP) Ac. ANTI CYTOMEGALOVIRUS Ac. ANTI COLLOIDE Ac. ANTI CORIOMENIN. LINFOCIT. Ac. ANTI COXACHIE Ac. ANTI CUORE Ac. ANTI CUTE Ac. ANTI DNA Ac. ANTI DNA MITOCONDRIALE Ac. ANTI DNA Nativo Ac. [elkalab.com]
ANTIGENE 50 CARBOSSIEMOGLOBINA CARIOTIPO CASEINA CATECOLAMINE PLASMATICHE CATECOLAMINE URINARIE CATENE KAPPA E LAMBDA CATENE KAPPA E LAMBDA URINARIE CDT - TRANSFERRINA CARBOIDRATO CARENTE CDT-TRANSFERRINA CARBOIDRATO CARENTE CEA CERULOPLASMINA CHINIDINA CHLAMYDIA [ricerchecliniche.it]
- Toxoplasma Gondii
GONDII IgG Ab TOXOPLASMA GONDII IgM Ab TPHA TRANSAMINASES (AST + ALT) TRIGLYCERIDES TRIPLE SCREEN TROPONINE I TSH RECEPTOR Ab (TRAB) URINES – ROUTINE V.Z.V IgM VIRUS A/H1N1 VITAMINE B12 VITAMINE D, 25 OH VITESSE DE SEDIMENTATION VMA WIDAL X-RAY Zika [ephatamedic.com]
TOXOPLASMA GONDII DNA TRANSAMINASI GOT TRANSAMINASI GPT TRANSFERRINA CARBOIDRATO CARENTE TRANSFERRINA TRICHOMONAS VAGINALIS ANTIGENE TRICLOROETANOLO TOTALE TRICLOROETANOLO URINARIO TRIGLICERIDI TRIPTASI TROPONINA I TSH dosaggi seriati dopo TRH TUMOR NECROSIS [fioroni.it]
GONDII ANTICORPI - CONFERMA TOXOPLASMOSI IGG QUANTITATIVE TOXOPLASMOSI IGM QUANTITATIVE TPA - ANTIGENE POLIPEPTIDICO TISSUTALE - URINARIO TPA - ANTIGENE POLIPEPTIDICO TISSUTALE - PLASMATICO TPHA TPHA SCREENING TRACCE BIOLOGICHE - IDENTIFICAZIONE TRANSAMINASI [eurolabgiovinazzo.it]
Treatment
It is converted in the liver to...Anecortave acetateInvestigated for use/treatment in glaucoma and macular degeneration.NCX 1022Investigated for use/treatment in atopic dermatitis.TixocortolA corticosteroid used for the symptomatic treatment of rhinitis [go.drugbank.com]
In general, the higher the initial value of the serum nonprotein-bound cortisol and 17-hydroxycorticosteroid, the greater the probability of death during the first year of treatment. [nejm.org]
The levels of circulating androgens may be reduced by antiandrogen treatment. [dermnetnz.org]
Measurements of 17-hydroxycorticosteroids (17-ketogenic steroids) are used in the diagnosis and treatment of various diseases of the adrenal or pituitary glands and gonadal disorders. (b) Classification. Class I (general controls). [law.cornell.edu]
Treatment Treatment depends on the etiology of Cushing's syndrome. [glowm.com]
Prognosis
Prevention, and Complications Prognosis good to very good in most individuals if untreated, adrenal crisis can lead to death within 1-6 weeks males usually have normal fertility; females may be abnormal fertility Prevention genetic counseling may help [medbullets.com]
The prognosis is good for benign adenoma, whereas the prognosis is poor for carcinoma. 1 Adashi EY, Levin PA: Pathophysiology and evaluation of adrenal hyperandrogenism. [glowm.com]
Etiology
Treatment Treatment depends on the etiology of Cushing's syndrome. [glowm.com]
Epidemiology
Gamaleya Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the U.S.S.R., Moscow J. PLANELLES, N. OZERETSKOVSKY & O. DJEKSENBAEV Authors J. PLANELLES You can also search for this author in PubMed Google Scholar N. [nature.com]
Epidemiology Familial glucocorticoid deficiency (FGD) is a rare disease, and only isolated case reports are documented. [emedicine.medscape.com]
Pathophysiology
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Corticosterone is a steroid hormone and a precursor molecule for aldosterone. [mayomedicallaboratories.com]
• Review pathophysiology & function of adrenal hormones • Indications for adrenal disorder tests • Correlate lab findings with disorders of the adrenal medulla and adrenal cortex • Significance of specimen variables • Inner medulla secretes hormones that [quizlet.com]
View Article : Google Scholar : PubMed/NCBI 9 Lipsett MB, Hertz R and Ross GT: Clinical and pathophysiologic aspects of adrenocortical carcinoma. Am J Med. 35:374–383. 1963. [spandidos-publications.com]
(Adashi EY, Levin PA: Pathophysiology and evaluation of adrenal hyperandrogenism. [glowm.com]
Prevention
and Complications Prognosis good to very good in most individuals if untreated, adrenal crisis can lead to death within 1-6 weeks males usually have normal fertility; females may be abnormal fertility Prevention genetic counseling may help parents with [medbullets.com]
Such observations, as the fact that an indomethacin-induced intestinal ulcer can be prevented by ethylestrenol, orthat cortisol aggravates certain infections, reveal nothing about how these hormones work; but only findings of this type can tell us where [books.google.it]
The study, described by preventive medical expert Neil Nedley, MD, author of “Proof Positive,” came out in Nutrition Review in May 1986 in an article titled “Associations between nutrition and behavior” by R. J. Prinz and D. B. Riddle. [business.inquirer.net]
Loss of ACTH suppressibility by physiologic doses of glucocorticoid: 1 mg dexamethasone at hs does not prevent the 8 am rise of cortisol to greater than 10 ug/dl. [enotes.tripod.com]
Treatment of classic congenital hyperplasia Treatment of classic congenital hyperplasia aims to replace glucocorticoid (cortisol) to prevent excessive ACTH secretion, using a small dose of dexamethasone, usually 0.5mg at nighttime. [dermnetnz.org]