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Abdominal Aortic Thrombosis

Thrombosis Aorta Abdominal


Presentation

  • Abdominal aortic thrombosis needs to be considered in a patient who presents with an anterior spinal artery syndrome, which, if present, must be treated as rapidly as possible to preserve motor and sensory function.[ncbi.nlm.nih.gov]
  • We present the case of a 72-year-old-man, who referred to the emergency Department of our hospital because of persistent severe abdominal and perineal pain.[ncbi.nlm.nih.gov]
  • We present a complicated case of an otherwise healthy neonate who developed thrombosis of abdominal aorta with renal failure.[ncbi.nlm.nih.gov]
  • Case Presentation: We report a case of young male suffering from AIDS, presented with chronic diarrhea and abdominal pain. Patient was diagnosed as a case of partial abdominal aortic thrombosis.[nigjcardiol.org]
  • On clinical examination, pulsations in the right leg were absent (peripheral pulses were present upon admission). Capillary refill and skin temperature of the lower extremities were unremarkable. Waxing and waning paresis of both legs was present.[academic.oup.com]
Coronary Artery Disease
  • Mathews MJ, Liebenberg L, Mathews EH: The mechanism by which moderate alcohol consumption influences coronary artery disease .[cureus.com]
  • artery disease should always be considered in such patients according to the available guidelines, despite of being asymptomatic. [5] , [6] Conclusion Abdominal symptoms are amongst the most frequent complaints of patients with AIDS.[nigjcardiol.org]
  • Four patients required ICU stay due to underlying, significant coronary artery disease & reperfusion syndrome. Bilateral leg fasciotomy was done in 8 patients.[ispub.com]
Perineal Pain
  • We present the case of a 72-year-old-man, who referred to the emergency Department of our hospital because of persistent severe abdominal and perineal pain.[ncbi.nlm.nih.gov]
Vascular Disease
  • You are more likely to have vascular disease as you get older.[icdlist.com]
  • diseases I73.89 Other specified peripheral vascular diseases I73.9 Peripheral vascular disease, unspecified I74 Arterial embolism and thrombosis I74.0 Embolism and thrombosis of abdominal aorta I74.01 Saddle embolus of abdominal aorta I74.09 Other arterial[icd10data.com]
  • Search strategy: The Cochrane Peripheral Vascular Diseases Group searched their trials register (last searched 13 July 2009) and the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library , (last searched Issue 3, 2009).[cochrane.org]
  • Smoking is unarguably linked with peripheral vascular disease-thromboangitis obliterans. Three of the four smokers, presumed to have hypercoagulation had clinical features of peripheral vascular disease.[jpgmonline.com]
  • With regard to late cardiovascular problems, cisplatin is thought to initiate degenerative processes of vessel walls, thus causing occlusive vascular disease in the long run.[bmccancer.biomedcentral.com]

Workup

  • Workup for autoimmune diseases and inherited and acquired thrombotic diseases was all negative.[cureus.com]
  • A thorough workup of his past medical history revealed that the patient was admitted previously 22 nd August 2012, prior to current admission.[nigjcardiol.org]
  • However, we did not have a serologic workup.[jpgmonline.com]

Treatment

  • The treatment of abdominal aortic thrombosis in neonates should be considered on a case-by-case basis because the available data on the condition are limited to case report and series.[ncbi.nlm.nih.gov]
  • Other treatments include medicines and surgery.[icdlist.com]
  • Early diagnosis is essential for effective treatment.[psjd.icm.edu.pl]
  • Clinicians should be aware and alert of unprovoked thrombosis to promote timely treatment and prophylaxis.[nigjcardiol.org]
  • Treatment options include open surgical repair, axillobifemoral grafting or endovascular aortic repair. The patient received an aorto-bifemoral graft.[academic.oup.com]

Prognosis

  • Neonatal aortic arch thrombosis: analysis of thrombophilic risk factors and prognosis . Cardiol young . e-pub ahead of print, 21 January 2013, doi:10.1017/S1047951112002077. 4. Hamilton RM , Penkoske PA , Byrne P , Duncan NF .[nature.com]
  • Prognosis of abdominal aortic aneurysms: a population-based study. N Engl J Med 1989; 321:1009-1014. ‎[books.google.de]
  • Case presentation A 49 year old patient presented with advanced seminoma by bulky retroperitoneal disease and left-sided supraclavicular lymphadenopathy, corresponding to stage III (Lugano classification) and to the good prognosis group according to IGCCCG[bmccancer.biomedcentral.com]
  • The results of this study suggest that the UIP subtype on HRCT did not show a statistically significant association but could be associated with a poor prognosis.[kjim.org]
  • […] aortic injury Long-term surveillance in traumatic aortic injury Iatrogenic aortic dissection Aortic aneurysms Thoracic aortic aneurysms Abdominal aortic aneurysm Definition Risk factors Natural history Diagnosis Abdominal aortic aneurysm repair Long-term prognosis[escardio.org]

Etiology

  • Clinicians should also consider etiologies other than infectious as cause of abdominal pain to prevent any catastrophe. Clinicians should be aware and alert of unprovoked thrombosis to promote timely treatment and prophylaxis.[nigjcardiol.org]
  • Journal of Cardiovascular Surgery 2017 December;58(6):848-53 Changes in abdominal aortic aneurysm epidemiology Fredrik LILJA, Anders WANHAINEN, Kevin MANI * The Journal of Cardiovascular Surgery 2017 April;58(2):238-51 Overview of the current knowledge on etiology[minervamedica.it]
  • Other etiologic factors including atrial myxoma, vegetations in bacterial or fungal endocarditis, prosthetic valve thrombus may be infrequently seen [ 2 - 5 ] Its diagnosis depends on the clinical presentation including acute hypertension, abdominal symptoms[pulsus.com]
  • Article INTRODUCTION Etiological diagnosis of arterial embolisms is a complex task.[revespcardiol.org]
  • Histopathologic character and current etiologic concepts. Arch Surg 1975; 110:561-566. 38. Nader RG, Barr F, Rubin R, Hirshfeld JW, Eisen HJ, Laposata E. Aortic degenerative changes and thrombus formation.[jpgmonline.com]

Epidemiology

  • […] aortic repair Abdominal endovascular aortic repair Surgery Ascending aorta Aortic arch Thoracoabdominal aorta Abdominal aorta Acute thoracic aortic syndromes Definition Pathology and classification Acute aortic dissection Definition and classification Epidemiology[escardio.org]
  • Jean-Baptiste, RICCO, Romain BELMONTE, Guilio ILLUMINATI, Xavier BARRAL, Fabrice SCHNEIDER, Bertrand CHAVENT The Journal of Cardiovascular Surgery 2017 December;58(6):848-53 Changes in abdominal aortic aneurysm epidemiology Fredrik LILJA, Anders WANHAINEN[minervamedica.it]
  • The risk of rupture is also greater for women. [ 2 ] Epidemiology The prevalence of AAAs is estimated at 1.3-12.7% in the UK. [ 3 ] Symptomatic AAA in men has an incidence of 25 per 100,000 at age 50, which increases markedly to 78 per 100,000 in those[patient.info]
  • Epidemiology and potential for prevention of abdominal aortic aneurysm. Brit J Surg. 1998;85:55–62. Ernst CB. Abdominal Aortic Aneurysm. N Engl J Med .1993;328:1167-72. U.S. Preventive Services Task Force.[acep.org]
  • […] mortality for an already ruptured AAA has slowly decreased over several decades but remains higher than 40%. [39] However, if the AAA is surgically repaired before rupture, the post-operative mortality rate is substantially lower: approximately 1-6%. [80] Epidemiology[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • An introductory section concisely explains the complex pathophysiology of thrombosis and hemostasis.[books.google.com]
  • Thromboembolic complications in the nephrotic syndrome: Pathophysiology and clinical management. Thromb Res 2006;118:397-407. 4. Gargah T, Abidi K, Nourchene K, Zarrouk C, Lakhoua MR. Thromboembolic complications of childhood nephrotic syndrome.[sjkdt.org]
  • Of note – there are clinicians who claim that anticoagulation has no place in the treatment of mural thrombus as the pathophysiology is not one of hypercoagulability.[angiologist.com]
  • The pathophysiology of aortic thrombi is not well -defined.[revespcardiol.org]
  • Adventitial inflammatory infiltrate is present. [18] However, the degradation of the tunica media by means of a proteolytic process seems to be the basic pathophysiologic mechanism of AAA development.[en.wikipedia.org]

Prevention

  • Background: Deep vein thrombosis ( DVT ) is one of the most common, preventable complications of surgery.[cochrane.org]
  • For, as Leriche 2 pointed out, a number of cases are not reported because recovery prevented confirmation of the diagnosis.[annals.org]
  • Many conditions can cause the blood to clot too much or prevent blood clots from dissolving properly.[icdlist.com]
  • Although arterial pulsations were absent, perfusion was sufficient to prevent cyanosis and to maintain normal capillary refill. Complete TAAA is a surgical emergency.[academic.oup.com]
  • Present case justifies that vascular thrombosis should also be considered in differential diagnosis and a timely workup to be done to prevent any catastrophe. References 1. Mulaudzi TV. HIV associated vasculopathy.[nigjcardiol.org]

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