Critical illness relative corticosteroid insufficiency (CIRCI) should be considered in any patient with refractory shock after adequate restoration of circulatory volume has been achieved. [cancertherapyadvisor.com]

If the patient is undergoing cholecystectomy for acute cholecystitis, antimicrobial therapy should be discontinued within 24 hours unless there is evidence of infection outside the wall of the gallbladder. Enlarge Print Table 3. [aafp.org]

She developed periumbilical hemorrhagic bullae and finally had a fatal outcome with medical therapy. Severe intra-abdominal infection such as pneumatosis intestinalis should be suspected when periumbilical bullae increase in size. [ncbi.nlm.nih.gov]

The perceived severity of adverse effects reported were: Acute neuromuscular blockade (8.0), severe allergic reaction (7.5), ototoxicity (7.4), nephrotoxicity (7.1), antibiotic-associated colitis (7.0), peripheral neuropathy (5.3), general neurological [ncbi.nlm.nih.gov]