Abdominal pregnancy is a rare type of ectopic pregnancy, in which the embryo attaches to virtually any surface in the abdominal cavity. The diagnosis can often be missed until advanced fetal age is reached, while main symptoms include abdominal tenderness, an easy palpation of the limbs of the fetus and gastrointestinal complaints. Both maternal and fetal mortality rates are substantially higher in abdominal pregnancy, implicating that an early diagnosis is detrimental.
Abdominal pregnancy (AP), in which the fetus grows outside the female reproductive tract and within the peritoneum, is a very rare type of ectopic pregnancy (EP), accounting for 1% of all EPs . The incidence rate ranges considerably from study to study (1 in 400-50,000 live births), but it must be noted that abdominal pregnancy is the only type of EP that can end as a successful delivery of a full-term newborn   . AP is further divided into primary, when the fertilized ovum directly implants at a site within the peritoneal cavity (bowels, the appendix, spleen, and virtually any other organ, as well as blood vessels, uterine structures, and the omentum, are reported sites), whereas secondary implies implantation of the ovum in the peritoneum after initial adhesion in the reproductive tract and its rupture from various reasons  . Regardless of the type, the clinical presentation is comprised of the following symptoms - persistent pain, either in the abdomen or in the suprapubic area, nausea, vomiting, painful movements of the fetus, regular menstruation cycles, vaginal discharge (bloody), and malaise    . Because the fetus grows adjacent to several vital organs and blood vessels, both the mother and the fetus are at a much higher risk for complications such as severe and uncontrollable bleeding, maternal bowel obstruction, infections, pulmonary embolism, fistula formation (between the amniotic sac and the intestines) and even disseminated intravascular coagulation   . Furthermore, perinatal mortality rates reach as high as 50%, and up to half of all children born after an abdominal pregnancy have some congenital abnormality - torticollis, facial or cranial asymmetry, limb defects or deficits of the central nervous system (CNS) are most common, with oligohydramnios being the presumably pathogenic mechanism   . Maternal mortality rates, on the other hand, are somewhat lower (around 12%), but these numbers suggest that an early diagnosis can be life-saving .
Entire Body System
- Abdominal Pain
She suffered from abdominal pain at 16 weeks gestation. At admission, obstetrical examination and transabdominal ultrasonography revealed that it was uterine pregnancy with a single living fetus and oligohydramnios. [ncbi.nlm.nih.gov]
- Abdominal Mass
This case highlights the importance of excluding pregnancy in any woman of reproductive age with undiagnosed abdominal mass and utero-vaginal prolapse before any manipulation. [ncbi.nlm.nih.gov]
If she presents with an ABDOMINAL MASS and a SINUS on her abdominal wall (rare), the sinus may be arising in an ectopic pregnancy. Probe it, you may feel fetal bones. Open it with great care not to injure her gut. [web.archive.org]
On examination, there may be abnormal presentation, easily palpable fetal parts, uneffaced and displaced cervix and palpation of abdominal mass seperate from uterus . High index of suspicion is first step in the diagnosis. [ijcasereportsandimages.com]
mass, confusing the diagnosis. 2 Computerized tomography (CT) and nuclear magnetic resonance clearly define the pathology and help the diagnosis of adherence and other organs affected, although these are not absolutely necessary. 2,3,4 Some authors suggest [scielo.br]
Obstet Gynecol Surv 1991, 46: 515-525. 10.1097/00006254-199108000-00003 View Article Google Scholar Ede J, Sobnach S, Castillo F, Bhyat A, Corbett JH: The lithopedion – an unusual cause of an abdominal mass. S Afr J Surg 2011, 49: 140-141. [doi.org]
- Periumbilical Pain
We attribute the patient’s continuous periumbilical pain at presentation to irritation of the visceral peritoneum somewhere between the jejunum and transverse colon, originating from the placental attachment site. [doi.org]
[…] and edema and protein in the urine abdominal aortic aneurysm an aneurysm of the abdominal aorta associated with old age and hypertension abdominal aorta a branch of the descending aorta toxaemia of pregnancy an abnormal condition of pregnancy characterized [vocabulary.com]
Methyldopa and nifedipine were commenced for pregnancy-induced hypertension from 22 weeks of gestation. [doi.org]
Traditionally, pregnant mommies experience low blood pressure when pregnant; however, it is also likely that women may develop hypertension due to disturbance in vessels or alteration in the secretion of some hormones/neurotransmitters. [newkidscenter.com]
History and physical examination Symptoms of hepatic rupture include the following: RUQ pain and tenderness Possible history of pregnancy-induced hypertension Hemorrhagic shock Distended abdomen Workup The diagnosis can be confirmed through CT findings [emedicine.medscape.com]
- Reduced Fetal Movement
A 22-year-old woman, gravid 3 para 2 was referred to our centre from a district hospital with complaint of generalized abdominal pain and reduced fetal movements. [ncbi.nlm.nih.gov]
Case presentation A 22-year-old woman, gravid 3 para 2 was referred to our centre from a district hospital with complaint of generalized abdominal pain and reduced fetal movements. [bmcresnotes.biomedcentral.com]
- First Trimester Bleeding
The prevalence of ectopic pregnancy among women presenting to an emergency department with first trimester bleeding, pain, or both ranges from 1% to 16% . [ncbi.nlm.nih.gov]
Prior reports have neglected to discuss the implications of leaving the placenta in situ on breastfeeding and lactation. [ncbi.nlm.nih.gov]
Wu MC, Huang WC, Lin HH, Hsiao SM: Severe intra-abdominal bleeding from neglected omental implantation of ectopic tissue after methotrexate treatment for persistent ectopic pregnancy. Fertil Steril 2011;95:2435.e2431-e2433. [karger.com]
A 35-year-old, para 2, unbooked, Ethiopian Somali woman presented with amenorrhea of 9 months' duration, abdominal pain, and painful fetal movements of 4 months' duration. [ncbi.nlm.nih.gov]
The 28-year-old woman in this instance had a history of amenorrhea and pelvic inflammatory disease. She had previously undergone dilatation and curettage, as well as tuboplasty. Fertility treatment was used for her to successfully conceive. [auntminnie.com]
At 2 months amenorrhea she gave a history of acute abdominal pain associated with spotting per vaginum. Emergency ultrasound done elsewhere at that time confirmed the presence of single live intrauterine gestation. [appliedradiology.com]
Unfortunately, the diagnosis of an abdominal pregnancy is often missed, especially in the first few months of gestation, and studies report that more than 50% of cases were not diagnosed on regular ultrasonographic exams   . For this reason, clinical judgment is necessary during diagnostic workup. A high index of suspicion must be present if patients report excessive abdominal pain in the first semester, bleeding, previous pelvic surgery, and a history of infertility, implying that a properly obtained patient history is vital in making a presumptive diagnosis . A meticulous physical examination is equally important, as relatively easy palpation of fetal limbs and an abnormal lie, as well as abdominal or suprapubic tenderness, are important features of AP  . Once clinical criteria have been solidified, imaging studies are used for confirmation. Standard fetal ultrasonography, however, may not reveal any pathological findings unless the physician patiently looks for the uterus and reveals an empty uterine cavity . Insertion of a balloon catheter into the uterus is often recommended to confirm the absence of the fetus inside the uterus  . A definite diagnosis can be made by performing more advanced imaging studies, either computed tomography (CT) or magnetic resonance imaging (MRI)  . Laboratory studies are usually normal for a regular pregnancy, showing high levels of human chorionic gonadotropin (βhCG) and/or serum alpha-fetoprotein (AFP) .
Early diagnosis and treatment are advised and the choice of treatment is crucial. A successful case of conservative treatment with combined systemic and intra-amniotic methotrexate is presented. [ncbi.nlm.nih.gov]
Uterine anomalies, their imaging and diagnosis, as well as the patient's subsequent reproductive prognosis are discussed. [ncbi.nlm.nih.gov]
Treatment and prognosis It is a serious and potentially life-threatening condition. Maternal mortality associated with intra-abdominal pregnancy is estimated at 7.7 times that of other locations of ectopic pregnancy 6, with a mortality rate of 5% 8. [radiopaedia.org]
Tamarit G, Lonjedo E, Gonzalez M, Tamarit S, Domingo S, Pellicer A: Combined use of uterine artery embolization and local methotrexate injection in interstitial ectopic pregnancies with poor prognosis. Fertil Steril 2010;93:1348 e1341-e1344. [karger.com]
Ectopic pregnancies should be identified early and evaluated for the etiology of the presentation. Rarely, an ectopic pregnancy implants at an extratubal location. [ncbi.nlm.nih.gov]
The etiology and mechanism of development of idiopathic CTEV is unknown ; one can only speculate about the role of AAP in the development of CTEV. [webmedcentral.com]
[…] further clarify the disease pre-eclampsia which was previously thought (1980's) to require a uterus for it to occur, however pre-eclampsia's occurrence in abdominal pregnancy (with the conceptus outside the uterus) helped throw light on pre-eclampsia's etiology [en.wikipedia.org]
Article information Author: Gwinyai Masukume First submitted: 13 November 2014 Accepted: 20 November 2014 Last updated: 01 January 2019 Reviewer comments Author info: Division of Epidemiology and Biostatistics, School of Public Health, Faculty of Health [en.wikiversity.org]
[…] placental regression.  Complications of leaving the placenta can include residual bleeding, infection, bowel obstruction, pre-eclampsia (which may all necessitate further surgery)   and failure to breast feed due to placental hormones.  Epidemiology [doi.org]
Multiparity and poor socio-economic status are implicated as epidemiological factors 7. Clinical presentation can be variable with abdominal pain occurring at 16-17 weeks gestation 8, 9 as was observed in our patient. [ncbi.nlm.nih.gov]
However, only one of nine women who reached the hospital alive had an accurate preoperative diagnosis of abdominal pregnancy, which suggests that preventing abdominal pregnancy-related death may depend, at least in part, upon increasing physicians' awareness [ncbi.nlm.nih.gov]
Enough fluid intake Drinking sufficient quantities of water can prevent abdominal pain caused by constipation and bloating. It keeps the metabolic system up and going and prevents dehydration. [newkidscenter.com]
When an abdominal pregnancy is ended surgically, the surgeon must take steps to prevent heavy bleeding at the place of implantation. [everydayhealth.com]
Treatment and Prevention “Modern medicine can provide open treatment only and keep the tube in some cases. In case of surgical procedure, laparoscopy procedure is used. [pinkycloud.com]
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