Presentation
A 29-year-old man presented with acute glomerulonephritis five weeks following completion of combined chemotherapy (bleomycin-vinblastine) and abdominal radiation for testicular carcinoma. [ncbi.nlm.nih.gov]
Interim results from the study of 26 individuals were presented by Danielle Novetsky Friedman at the 2016 Cancer Survivorship Symposium held in San Francisco. [curetoday.com]
We report the case of a patient who presented 3 abdominal solid malignancies within 3 years, 29 years after abdominal radiotherapy for a testicular seminoma, namely 2 colon cancers and a peritoneal mesothelioma. [archive-ouverte.unige.ch]
Gastrointestinal
-
Recurrent Abdominal Pain
But we've all seen many patients who come to the ED for recurrent abdominal pain, some of whom carry known diagnoses, some of whom have repeatedly defied diagnosis. [content.time.com]
Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood. Cochrane Database Syst Rev (1): CD003019, 2008. [cancer.gov]
-
Chronic Abdominal Pain
Certainly for patients who have had chronic abdominal pain, seeing three CTs documented on the radiology system over the past year or so, we may rethink ordering that fourth CT, particularly if all other testing is normal. Dr. [content.time.com]
-
Peritoneal Disease
Whole Abdominopelvic Radiotherapy using Intensity-modulated Arc therapy in the Palliative Treatment of chemotherapy-resistant ovarian cancer with bulky peritoneal disease: A single- institution experience. [cancerjournal.net]
Neurologic
-
Meningism
If the spleen isn't functioning, then the risk of infection is higher and may be life-threatening: sepsis or meningitis. Fortunately, there is a vaccination that we can give...but it hasn't been done routine because we just didn't think of it. [slideshare.net]
Workup
METHODS: All subjects of this comparative study underwent a complete obstetrical clinical workup comprising history, general physical examination, abdominal and pelvic examination, and relevant investigations. [ncbi.nlm.nih.gov]
Inpatient Considerations Patients with suspected placental abruption should be admitted for workup until deemed clinically stable and ready for discharge/outpatient follow-up or delivered for medical indication. [unboundmedicine.com]
Campylobacter, and infectious colitis), complete blood count, and electrolyte profile.[ 30 ] This workup and treatment is also considered for patients who progress to grade 3 or 4 diarrhea while taking loperamide. [cancer.gov]
Radiological et al. [8] included enlargement of the width of the upper workup consisted of chest X-ray, CT scan of the ab- portion of the diaphragmatic boost fields to 18 to 20 cm domen and pelvis, and intravenous pyelogram (IVP). [docslide.net]
Serum
-
Creatinine Increased
Mean serum creatinine increased from 0.86 0.18 mg/dL at baseline to 1.12 0.27 mg/dL at 12-24 months (p 0.001), then stabilized. [ncbi.nlm.nih.gov]
Biopsy
-
Liver Biopsy
Hepatic veno-occlusive disease, a known complication of whole abdominal radiation and certain chemotherapy regimens, was confirmed by liver biopsy in both cases. CA-125 levels may not be reflective of disease status in this setting. [ncbi.nlm.nih.gov]
Treatment
CT treatment planning studies were obtained with the entire peritoneum identified as the target volume. Simulator designed blocks were projected over the CT scans throughout the treatment volume. [ncbi.nlm.nih.gov]
Prognosis
The Prognosis: Pittsburgh has to consider itself fortunate that Marte’s injury wasn’t worse. [sportsnaut.com]
The presence of associated concurrent fetal bradycardia carries a poorer prognosis. [radiopaedia.org]
See: Couvelaire uterus Prognosis Although maternal mortality is unusual, other than as noted, the perinatal mortality is between 20% and 30%. [medical-dictionary.thefreedictionary.com]
Placental abruption: risk factors, management and maternal-fetal prognosis. Cohort study over 10 years. Eur. J. Obstet. Gynecol. Reprod. Biol. 2014 Aug; 179 :100-4. [ PubMed : 24965988 ] 14. Rhodes AM. [ncbi.nlm.nih.gov]
Etiology
Keywords Abdomen/radiation effects — Adenocarcinoma/etiology — Cecal Neoplasms/etiology — Humans — Male — Mesothelioma/etiology — Middle Aged — Neoplasms, Second Primary/etiology — Peritoneal Neoplasms/etiology — Radiotherapy/adverse effects — Seminoma [archive-ouverte.unige.ch]
Etiology Etiology Pathophysiology High SAAG ascites 1.1 g/dL (obsolete term: transudate) Portal hypertension Presinusoidal Splenic or portal vein thrombosis Schistosomiasis Sinusoidal Hepatic (common) Cirrhosis Alcohol-related liver disease Liver metastases [amboss.com]
Risk of placental abruption is higher if: History placental abruption in first pregnancy Hypertensive disorders in the index pregnancy At extremes of age in the reproductive window Etiology and Pathophysiology Acute Etiology of bleeding at the decidua [unboundmedicine.com]
Placental abruption is also called abruptio placentae. [1] [2] Etiology The exact etiology of placental abruption is unknown. However, a number of factors are associated with its occurrence. [ncbi.nlm.nih.gov]
Other features include: uterine contractions and irritability lumbar pain maternal/ fetal compromise secondary to exsanguination The exact etiology is unknown, but the final pathophysiology is likely to rupture of a spiral artery with hemorrhage into [radiopaedia.org]
Epidemiology
Garner MJ, Turner MC, Ghadirian P, Krewski D (2005) Epidemiology of testicular cancer: an overview. Int J Cancer 116 (3): 331–339. [nature.com]
In fact, according to a study conducted in San Francisco and published in the journal Epidemiology, you should pay close attention to how much electromagnetic radiation you are exposed to. [smartparenting.com.ph]
Table 1 Epidemiological data and trauma mechanism. [scielo.br]
“There are major concerns with taking the atomic bomb survivor data and trying to understand what the risk might be to people exposed to CT scans,” says David Richardson, an associate professor of epidemiology at the University of North Carolina Gillings [scientificamerican.com]
Therefore, when the uterine tissue stretches suddenly, the placenta remains stable and the vascular structure connecting the uterine wall to the placenta tear away. [3] [4] Epidemiology Placental abruption is a relatively rare condition but requires emergent [ncbi.nlm.nih.gov]
Pathophysiology
The key factor in the pathophysiology is hemorrhage at the decidual-placental interface. [ncbi.nlm.nih.gov]
Other features include: uterine contractions and irritability lumbar pain maternal/ fetal compromise secondary to exsanguination The exact etiology is unknown, but the final pathophysiology is likely to rupture of a spiral artery with hemorrhage into [radiopaedia.org]
In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. . Accessed March 23, 2016. Gastric cancer. [mayoclinic.org]
Etiology Etiology Pathophysiology High SAAG ascites 1.1 g/dL (obsolete term: transudate) Portal hypertension Presinusoidal Splenic or portal vein thrombosis Schistosomiasis Sinusoidal Hepatic (common) Cirrhosis Alcohol-related liver disease Liver metastases [amboss.com]
Risk of placental abruption is higher if: History placental abruption in first pregnancy Hypertensive disorders in the index pregnancy At extremes of age in the reproductive window Etiology and Pathophysiology Acute Etiology of bleeding at the decidua [unboundmedicine.com]
Prevention
The results are useful to the National Centre for Radiation Protection in Saudi Arabia and other professional organizations elsewhere, to set up safety protocols to prevent paediatric patients from needless radiation and to establish diagnostic reference [ncbi.nlm.nih.gov]
They will help position you and apply protective coverings to prevent radiation exposure to healthy tissue. Radiation is typically applied one or more times a week for several weeks. [asbestos.com]
It's not clear what causes gastroesophageal junction or stomach cancer, so there's no way to prevent it. [mayoclinic.org]
Radiation therapy — especially when combined with chemo drugs such as 5-FU — may delay or prevent cancer recurrence after surgery and may help patients live longer. [cancer.org]
Are there options to prevent or treat these side effects? Yes. Your health care team can help you prevent or treat many side effects. Preventing and treating side effects is an important part of cancer treatment. [cancer.net]