The only patient who presented a smaller maxillary sinus in the atresia side also had facial malformations that may have influenced in the development of this sinusal cavity.10 In the seven cases, the patients did not present CT scan alterations suggesting [bjorl.org]

• Heart Disease

  Choanal atresia is frequently associated with other well described malformations, making up the so called C.H.A.R.G.E. syndrome (Coloboma of the eye; Heart disease; Atresia of the choana; Retarded growth, development or CNS anomalies; Genital hypoplasia [bjorl.org]

For these reasons, both diagnosis and surgical treatment happen later on, sometimes at the adult age, after complete facial development. [bjorl.org]

In 1927, Grove7, reported a case of choanal atresia in a child, and mentioned that nasal breathing is one of the most powerful factors in sinus disease prevention. [bjorl.org]