This case highlights novel presentations and treatments for acanthamoebic infection. [ncbi.nlm.nih.gov]

Acanthamoeba was confirmed as the causative agent four months after presentation when positive cultures were obtained from the cornea and from the conjunctiva. [doi.org]

Interestingly, amphotericin B was the only drug presenting an increase of IC 50 as a function of treatment duration. [ncbi.nlm.nih.gov]

Acanthameoba keratitis is a serious ophthalmological condition with a potentially vision-threatening prognosis. [ncbi.nlm.nih.gov]

“The key to it … is to recognize that the earlier you can diagnose these and initiate treatment, the better the prognosis,” Kaufman said. Currently, there are no U.S. [healio.com]

“I think that the take home message is that if one can wait and try to cure the infection medically and then do the transplant, the prognosis of the graft will be better,” she said. [eyeworld.org]

Disseminated disease and GAE carry a poor prognosis, and treatment strategies are not well defined; Acanthamoeba keratitis is a sight-threatening infection that carries a favorable prognosis when diagnosed and treated early. [emedicine.medscape.com]

Chałubinskiego 5, 02-004 Warsaw, Poland Abstract Amphizoic amoebae belonging to the genus Acanthamoeba are known as etiological agents of sight-threatening Acanthamoeba keratitis. [ncbi.nlm.nih.gov]

Eight Acanthamoeba species have been isolated as etiologic agents in Acanthamoeba keratitis : A. castellanii, A. polyphaga, A. culbertsoni, A. hatchetti, A. rhysodes, A. lugdunensis, A. quina and A. griffini. [en.vircell.com]

[…] with lymphocyte predominance Elevated red blood cells (RBCs) with disease progression in primary amoebic meningoencephalitis Culture CSF examination for trophozoites with Wright or Giemsa stain Consider viral panel testing to rule out most common viral etiologies [arupconsult.com]

This is why the clinical symptoms alone, as non- pathognomonic, are not sufficient to indicate an etiological agent of human keratitis. [intechopen.com]

Selection criteria: We included randomized controlled trials ( RCTs ) of medical therapy for AK, regardless of the participants’ age, sex, or etiology of disease. [cochrane.org]

De Jonckheere, Laboratory of Protozoology, Department of Microbiology, Institute of Hygiene and Epidemiology, J. Wytsmanstraat 14, B-1050 Brussels, Belgium. Search for other works by this author on: Johan F. [doi.org]

Epidemiologic significance of A. triangularis as a keratopathogen in Korea has been discussed. Morphologic features of Acanthamoeba cysts were examined under a microscope with differential interference contrast (DIC) optics. [ncbi.nlm.nih.gov]

Aetiology of suppurative corneal ulcers in Ghana and South India and epidemiology of fungal keratitis. Br J Ophthalmol86: 1211-1215. [raredisorders.imedpub.com]

The mechanisms associated with the pathogenesis remain unclear; however pathophysiological complications involving the CNS most likely include induction of pro-inflammatory responses, invasion of the blood-brain barrier and the connective tissue and neuronal [ncbi.nlm.nih.gov]

In part, this is due to an incomplete understanding of the pathogenesis and pathophysiology of the disease, diagnostic delays and problems associated with chemotherapeutic interventions. [doi.org]

The Dot/Icm secretion system was necessary for L. pneumophila to prevent the eukaryotic proliferation. [ncbi.nlm.nih.gov]