The systemic findings seen in acne fulminans are not present. [en.wikipedia.org]

The present study is constrained by several limitations. [biomeddermatol.biomedcentral.com]

Enhancing Healthcare Team Outcomes Patients with acne usually present to their primary care provider or nurse practitioner. [ncbi.nlm.nih.gov]

A 34 year-old white male presented with chronic, large, numerous, painful draining cysts of the trunk, groin and neck of ten years duration. The patient reported excessive alcohol ingestion and suicidal thoughts due to the pain. [dialnet.unirioja.es]

A round cystic swelling, 25 mm in diameter, was present on the right frontal area. [ijdvl.com]

[…] with the situation prior to treatment. [pubmed.ncbi.nlm.nih.gov]

Treatment Acne conglobata is challenging to treat. This type of acne absolutely must be treated by a dermatologist. Isotretinoin is by far the most common treatment and is generally the first treatment prescribed. [verywellhealth.com]

Facial Acne Conglobata Before and After Treatment With Adalimumab A, Study patient with severe facial nodular inflammatory acne. B, Clearance 3 months after initiation of treatment with adalimumab, 40 mg, twice monthly. [jamanetwork.com]

Treatment options include long-term systemic antibiotics, intralesional steroid injections, systemic retinoids, systemic steroids, adalimubab, electron beam radiation, and topical treatment.1 These treatments frequently lack efficacy and may have risks [dialnet.unirioja.es]

Topical treatments Topical treatments alone won’t work for AC. However, they may be used along with oral medications for better results. [healthline.com]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team [pubmed.ncbi.nlm.nih.gov]

Prognosis[28] The prognosis is good in patients treated appropriately and recurrence of acne fulminans is rare. Scarring and fibrosis may occur. [patient.info]

The course of AC is chronic and the prognosis is poor. Squamous cell carcinoma has been reported to arise in chronic scars of AC. [9] Treatment is difficult and often ineffective. Intensive antibiotic therapy is necessary. [ijdvl.com]

Differential Diagnosis The differential diagnoses of acne conglobata include but are not limited to the following: Acne and suppurative hidradenitis (PASH) syndrome Acne fulminans Acne vulgaris Acneiform papulonodules Bromoderma Iododerma Rosacea fulminans Prognosis [ncbi.nlm.nih.gov]

Etiology It is believed that Propionibacterium acnes, the same organism implicated in acne vulgaris, may play an important role in the disease by changing its reactivity as an antigen. [ncbi.nlm.nih.gov]

This finding suggests that these clinically distinct disorders may share a genetic etiology. Etiology The primary cause of acne conglobata remains unknown. [emedicine.medscape.com]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team [pubmed.ncbi.nlm.nih.gov]

It is a systemic disease of unknown etiology characterized by necrotizing acne associated with constitutional symptoms and laboratory abnormalities. [nature.com]

Epidemiology of acne vulgaris. Br J Dermatol. 2013;168:474–85. Article CAS Google Scholar Braun-Falco M, Kovnerystyy O, Lohse P, Ruzicka T. [biomeddermatol.biomedcentral.com]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team [pubmed.ncbi.nlm.nih.gov]

Epidemiology It is a rare condition and becoming rarer, due to improved treatment of acne. The typical patient is a young male aged between 13 and 22[24]. [patient.info]

Epidemiology Acne conglobata is not very common. Overall, it is more common in men than women. [ncbi.nlm.nih.gov]

Abstract The pathophysiology and treatment of hidradenitis suppurativa, acne conglobata, and dissecting cellulitis of the scalp, which constitute the follicular occlusion triad, are reviewed. [insights.ovid.com]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team [pubmed.ncbi.nlm.nih.gov]

Furthermore, the pathophysiology of acne indicates the presence of inflammatory markers especially in severe nodulocystic acne rather than it simply being ‘blocked pores,’” says Saxon D. [dermatologytimes.com]

Whether it occurs more frequently in any specific race is not known.[7] Pathophysiology Acne conglobata presents with deep burrowing abscesses that interconnect with each other via sinus tracts. [ncbi.nlm.nih.gov]

Whether it occurs more frequently in any specific race is not known. [7] Pathophysiology Acne conglobata presents with deep burrowing abscesses that interconnect with each other via sinus tracts. [statpearls.com]

The recommended treatment is oral isotretinoin which should be commenced early to prevent scarring. Treatment is required for at least five months, and further courses are sometimes necessary. [dermnetnz.org]

As you see improvements, you’ll need to stick with your treatment plan to make sure your medications keep working to prevent new nodules from forming. Your dermatologist will see you at regular intervals to monitor your treatment. [healthline.com]

Retinoids can help prevent the formation of comedones and perform anti-inflammatory functions in the skin. However, in severe cases, these topical treatments may not be as effective as their oral counterparts. [forhers.com]

The clinical effects of treatment options for acne conglobata are often unsatisfactory because of a long course of therapy, side effects, the high rate of recurrence, and failure to prevent scar formation. [intechopen.com]