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2.1
Acquired Functional Megacolon
Acquired Megacolon

Presentation

Organized alphabetically, the book presents brief, bulleted points on disease topics in a consistent 3-column format. All topics are evidence-based and include cited evidence-based references. [books.google.de]

Overall ~75% of cases present within six weeks of birth 4, and over 90% of cases present within the first five years of life. A very small number may present in the adult population 1. [radiopaedia.org]

An algorithm for the diagnosis and management of obstructive symptoms after a pull-through for Hirschsprung disease is presented. [uthsc.pure.elsevier.com]

Clinical Vignette A 76-year-old male presented from a nursing home with progressive abdominal distention. Due to cognitive decline, the patient was only able to provide a limited history of “abdominal pain.” [ijam-web.org]

Thus it presents a survey of today's problems in proctology. G. REGEMANN President of the rd 3 International Congress Contents The Future of Proctology, J. F. MONTAGUE. 1 I. Injuries of the Colon and Rectum Injuries of the Colon and Rectum, J. [books.google.com]

Gastrointestinal

  • Constipation

    Constipation can be broadly divided into 3 classes based upon the underlying physiologic cause; normal-transit constipation, slow transit constipation, and pelvic floor dysfunction. [aboutconstipation.org]

    Figure 1 Figure 2 Discussion Chronic constipation is very common and often more difficult to remedy than an acute onset of constipation. [npplweb.com]

    Chronic constipation will lead to... (other than encopresis) After puberty, which sex is more likely to be constipated? What other disease do you have to always have to consider when it looks like constipation? Two other major ones. [quizlet.com]

    It can cause severe constipation. Megacolon can be congenital and is often hereditary, or can gradually develop over many years of poor diet, constipation and/or laxative abuse. [liverdoctor.com]

    Treatment is aimed at eliminating constipation. Occasionally, in the case of persistent long-term constipation, surgical treatment (resection of the elongated portion of the intestine). [mymedinform.com]

  • Abdominal Distension

    A 61-year-old male, with long-standing abdominal distension, presented with generalised abdominal pain, shortness of breath, and marked abdominal distension. [nzma.org.nz]

    In case of any future constipation and abdominal distension, she should report at the emergency. [ghrnet.org]

    Case Report A 76-year-old woman admitted to surgery division of our hospital with chronic abdominal pain, abdominal distension, and constipation lasting for 10 days. [ispub.com]

    Moderate to severe colitis usually causes profuse diarrhea, abdominal distension with pain and occult colonic bleeding in some cases. [revistagastroenterologiamexico.org]

    Patients present with fever, abdominal tenderness, and distension or even with an acute abdomen. [clinicalgate.com]

Treatment

Significant updates on bariatric surgery, Barrett's esophagus, endoscopic ultrasound, endosonography, treatment of liver disease, and much more keep you current on the latest advances. [books.google.com]

It has enabled to avoid surgical treatment which should be carried out in these cases in which long-term conservative treatment failed. [ncbi.nlm.nih.gov]

A stepwise, logical approach to the diagnosis and management of patients experiencing obstructive symptoms following pull-through for Hirschsprung disease can facilitate treatment. [uthsc.pure.elsevier.com]

In patients requiring hospitalization, decompression using nasogastric tubes and rectal tubes may assist in treatment. [emedicine.medscape.com]

In: Treatment of acquired megacolon in the dog and cat. JAVMA 188, 1412-1416. [vetstream.com]

Prognosis

Where this is successful, the prognosis is good. However, in 3-4% of cases, colonic perforation complicates the presentation 2 and this and its sequelae significantly increase both mortality and morbidity. [radiopaedia.org]

Prognosis Prognosis, even if treated, is uncertain due to damage caused by the acute phase of infection. Between 25 and 30% of those who are infected will have severe and possibly fatal pathology. [patient.info]

Prognosis : guarded depending on stage of disease and choice of treatment. Pathogenesis Etiology Often idiopathic - dysfunction of colonic smooth muscle, progressive post-receptor defect in excitation-contraction coupling. [vetstream.com]

Prognosis Overall, prognosis is very good. Most infants with Hirschsprung's disease achieve good bowel control after surgery, but a small percentage of children may have lingering problems with soilage or constipation. [healthofchildren.com]

Affected individuals should talk to their physician and medical team about their specific case, associated symptoms and overall prognosis. [rarediseases.org]

Etiology

There are three etiological types of megacolon: acute, chronic, and toxic megacolon. [amboss.com]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

ELECTRIQUE MOTRICITE ANORECTAL ADULTE ETIOLOGIE MALFORMATION COLON TROUBLE FONCTIONNEL EXPLORATION ANUS RECTUM HOMME PATHOLOGIE DIGESTIVE GASTROENTEROLOGIE Keyword (en) MEGACOLON CONGENITAL IDIOPATHIC MANOMETRY ELECTRICAL ACTIVITY MOTRICITY ANORECTAL ADULT ETIOLOGY [pascal-francis.inist.fr]

The use of biofeedback for a colonic inertia etiology for chronic megacolon is probably not effective, although successful treatment of functional outlet obstruction with biofeedback has been reported. [emedicine.medscape.com]

The proper treatment must necessarily depend upon the accuracy of the diagnosis as to etiology in each patient. [pediatrics.aappublications.org]

Epidemiology

Chagas megacolon. [3] Of the 34% of asymptomatic patients who demonstrated similar patterns of autoantibodies, 84% of these individuals also had levels of beta1 autoantibody that are typical for Chags cardiomyopathy, which the authors stated mirrored the epidemiologic [emedicine.medscape.com]

Epidemiology It is found in South America and the South and Southwestern USA. [patient.info]

Pathophysiology

[…] those who have undergone a major surgical procedure Idiopathic ; possible factors include: Electrolyte imbalance Trauma ; major surgery Hypothyroidism Drugs ; (e.g., anticholinergic drugs, opioid analgesics, antipsychotics, calcium channel blockers ) Pathophysiology [amboss.com]

Pathophysiology Failure of motor function or obstruction to passage of feces → loss of colonic motor activity → normal defecation prevented over prolonged period → colon distends → further muscle degeneration → colon flaccid and filled with dry, hard [vetstream.com]

The authors also discuss the pathophysiology and clinical management of this surgical condition. The following core competencies are addressed in this article: Medical knowledge, Patient care. [ijam-web.org]

The pathophysiology of chronic megacolon is incompletely understood. It likely represents an amalgam of primary disorders involving muscular and nervous systems of the intestine. Much basic science work has been performed in this area. [emedicine.medscape.com]

[…] thickening of the enteric smooth muscle, but with an intact enteric nervous system. 4 Functional abnormalities of the enteric nervous system, the autonomic nervous system, enteric smooth muscle, or the interstitial cells of Cajal, may play a role in the pathophysiology [nzma.org.nz]

Prevention

[…] vaccine but the following may help aid prevention: Improved housing. [patient.info]

Prevention of colon enlargement may be achieved by consumption of food rich in fibers and specific measures against constipation. And timely treatment of inflammatory bowel disease may be another form of prevention against colon enlargement. [ic.steadyhealth.com]

Prevention Hirschsprung's disease is a congenital abnormality that has no known means of prevention. It is important to diagnose the condition early in order to prevent the development of enterocolitis. [healthofchildren.com]

Pathophysiology Failure of motor function or obstruction to passage of feces → loss of colonic motor activity → normal defecation prevented over prolonged period → colon distends → further muscle degeneration → colon flaccid and filled with dry, hard [vetstream.com]

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